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The map label for this gene is pip [H]

Identifier: 117918769

GI number: 117918769

Start: 350384

End: 351289

Strand: Direct

Name: pip [H]

Synonym: Shewana3_0312

Alternate gene names: 117918769

Gene position: 350384-351289 (Clockwise)

Preceding gene: 117918768

Following gene: 117918770

Centisome position: 7.05

GC content: 49.12

Gene sequence:

>906_bases
ATGATGGGCAATGGGCAGCAGTTGCATCTTGCACAATATGGTAATCCGCAGGGTATTCCACTGCTGTATTTGCATGGCGG
TCCAGGGGCGGGAGCTTCGGTCAGTGAACTGAGTTTATTTAACCCCGAGCACTACTGGATTTTACTGCTAGATCAACGTG
GTGCGGGACAATCACTGCCTACTGGCGAGTTGGAGCATAATCATTTAAATGGACTTATCAGCGATATTGAGGCGATTCGC
ATTCACTTAGGCATAGAACGTTGGTGCTTAGCGGGTGGCTCATTTGGCGCCACCTTAGCCTTAATTTACAGTGGTTTATT
TCCCCATCGAGTGATTGCCCAAGTGCTGTGGGCGGTGTTTATTCCCTCAGAGGCCGGTATTGAATGGCTCTATGCCCCCT
CGGGCGCAGCGCAGTTATATCCGCAGGCTTACCGTGAATTTGCTGCACCTTCTATTGGTTTGGCGGATTTATTTACGCAC
TATCAGCTAGGATTTAACGCCCAAGATGAAGCAACCCGTCATGAATTTGCCCGTCGCTGGATCCAATGGGAATTAACCTT
AGCGGGCGTACCAACAGGCTTGCCGAAGCGGCTTGCGGCGCCTTTGCTAGCCTTAGCTCAAATTGAGTTGCACTATGCAA
AAAATGATTACTTCAATATGTTCAGCATATTACAGCGGGTGACATCACAAGTCACAGCGCGTACCCTGCTATTACAAGGC
ACACAGGATGCTGTCTGTCCGGCACGTTTATTAGCCGCATTTTTGGCAAAAATCGACAACCCTAGGATACAAATTCATAC
CATTGTCGATGGTGGGCATTCGCTGAATAGTGACATACTCCCACTTGCCGTCACACTCGAGATCCAAGCCATGTGGACTT
GGATAAAGCGACAGGAGCTAGCATGA

Upstream 100 bases:

>100_bases
GTAGCTAAGTTGTCATCCACCAAGACATTTAACGAGCCTTATCCCGCCAATGATCACTGACGCCCATCAGCTTGCTCCTT
TTATCCGCCGTGATTGGTTG

Downstream 100 bases:

>100_bases
AATTAGCCGTTATTATTGCCGCCATTTTGGGATTAACTGCCTGCGCGGCCACCTCATCTCCTACCCCGGAGTCTCAATCC
TCATCTTCTGTGGTTGAGTC

Product: prolyl aminopeptidase

Products: NA

Alternate protein names: PIP; Prolyl aminopeptidase; PAP [H]

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MMGNGQQLHLAQYGNPQGIPLLYLHGGPGAGASVSELSLFNPEHYWILLLDQRGAGQSLPTGELEHNHLNGLISDIEAIR
IHLGIERWCLAGGSFGATLALIYSGLFPHRVIAQVLWAVFIPSEAGIEWLYAPSGAAQLYPQAYREFAAPSIGLADLFTH
YQLGFNAQDEATRHEFARRWIQWELTLAGVPTGLPKRLAAPLLALAQIELHYAKNDYFNMFSILQRVTSQVTARTLLLQG
TQDAVCPARLLAAFLAKIDNPRIQIHTIVDGGHSLNSDILPLAVTLEIQAMWTWIKRQELA

Sequences:

>Translated_301_residues
MMGNGQQLHLAQYGNPQGIPLLYLHGGPGAGASVSELSLFNPEHYWILLLDQRGAGQSLPTGELEHNHLNGLISDIEAIR
IHLGIERWCLAGGSFGATLALIYSGLFPHRVIAQVLWAVFIPSEAGIEWLYAPSGAAQLYPQAYREFAAPSIGLADLFTH
YQLGFNAQDEATRHEFARRWIQWELTLAGVPTGLPKRLAAPLLALAQIELHYAKNDYFNMFSILQRVTSQVTARTLLLQG
TQDAVCPARLLAAFLAKIDNPRIQIHTIVDGGHSLNSDILPLAVTLEIQAMWTWIKRQELA
>Mature_301_residues
MMGNGQQLHLAQYGNPQGIPLLYLHGGPGAGASVSELSLFNPEHYWILLLDQRGAGQSLPTGELEHNHLNGLISDIEAIR
IHLGIERWCLAGGSFGATLALIYSGLFPHRVIAQVLWAVFIPSEAGIEWLYAPSGAAQLYPQAYREFAAPSIGLADLFTH
YQLGFNAQDEATRHEFARRWIQWELTLAGVPTGLPKRLAAPLLALAQIELHYAKNDYFNMFSILQRVTSQVTARTLLLQG
TQDAVCPARLLAAFLAKIDNPRIQIHTIVDGGHSLNSDILPLAVTLEIQAMWTWIKRQELA

Specific function: Specifically catalyzes the removal of N-terminal proline residues from peptides [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S33 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR005944
- InterPro:   IPR002410 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.4.11.5 [H]

Molecular weight: Translated: 33214; Mature: 33214

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMGNGQQLHLAQYGNPQGIPLLYLHGGPGAGASVSELSLFNPEHYWILLLDQRGAGQSLP
CCCCCCEEEEEECCCCCCCEEEEEECCCCCCCCHHHHEEECCCEEEEEEEECCCCCCCCC
TGELEHNHLNGLISDIEAIRIHLGIERWCLAGGSFGATLALIYSGLFPHRVIAQVLWAVF
CCCCCHHHHHHHHHHHHHHHHEECHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHH
IPSEAGIEWLYAPSGAAQLYPQAYREFAAPSIGLADLFTHYQLGFNAQDEATRHEFARRW
CCCCCCCEEEECCCCCHHHCHHHHHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHH
IQWELTLAGVPTGLPKRLAAPLLALAQIELHYAKNDYFNMFSILQRVTSQVTARTLLLQG
EEEEEEEECCCCCCHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHEEEC
TQDAVCPARLLAAFLAKIDNPRIQIHTIVDGGHSLNSDILPLAVTLEIQAMWTWIKRQEL
CCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCEEEEEEEEHHHHHHHHHHHCC
A
C
>Mature Secondary Structure
MMGNGQQLHLAQYGNPQGIPLLYLHGGPGAGASVSELSLFNPEHYWILLLDQRGAGQSLP
CCCCCCEEEEEECCCCCCCEEEEEECCCCCCCCHHHHEEECCCEEEEEEEECCCCCCCCC
TGELEHNHLNGLISDIEAIRIHLGIERWCLAGGSFGATLALIYSGLFPHRVIAQVLWAVF
CCCCCHHHHHHHHHHHHHHHHEECHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHH
IPSEAGIEWLYAPSGAAQLYPQAYREFAAPSIGLADLFTHYQLGFNAQDEATRHEFARRW
CCCCCCCEEEECCCCCHHHCHHHHHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHH
IQWELTLAGVPTGLPKRLAAPLLALAQIELHYAKNDYFNMFSILQRVTSQVTARTLLLQG
EEEEEEEECCCCCCHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHEEEC
TQDAVCPARLLAAFLAKIDNPRIQIHTIVDGGHSLNSDILPLAVTLEIQAMWTWIKRQEL
CCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCEEEEEEEEHHHHHHHHHHHCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]