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The map label for this gene is rpiA [H]

Identifier: 116872376

GI number: 116872376

Start: 982047

End: 982718

Strand: Direct

Name: rpiA [H]

Synonym: lwe0958

Alternate gene names: 116872376

Gene position: 982047-982718 (Clockwise)

Preceding gene: 116872370

Following gene: 116872379

Centisome position: 34.9

GC content: 35.27

Gene sequence:

>672_bases
GTGAATCAGAAGAAAATTGCAGGAGAAAAAGCATGTGGATGGGTGAAAGATGGAATGGTTGTCGGACTTGGAACAGGGAG
TACTGTTTACTATACAATCGAAAAATTAGGAGAAATGGTACGTGACGGTCTCAATATTACTGGAATTGCTACATCTGAAG
AAACTGCAATACAAGCTAAAAAACTGGGCATCCCATTAAAATCTTTAAATGATGTAAAGCAAATAGATGTCACAATTGAT
GGAGCAGATGAAGTGAACAAAGATTTTCAAGGGATAAAAGGTGGAGGAGGAGCGCTTTTACGCGAAAAAATGGTAGCAGC
AGCTAGCTTGATGAATATTTGGGTAGTGGAAGAAAAGAAATTAGTGGAAGAACTTGGCGAATTTTCACTTCCAATAGAAG
TAATTCCATTTGGCTGGAAACAAATTAAGTGGAGTCTTGAAAAAGAAGCAATTGAAACAGAATTACGAAAAAATGATTCA
GGAAAAGTGTATCAGACAAATAATGGAAATTATATTTTGGACATTAAAAATCAAATTTTGACGAATCCAGTAGAATGGCA
AGAAAAACTAGCGGGGATTCCTGGAATTGTCGAGCATGGATTGTTTTTAGATTATGTGGATATAGTTATTTGTGGAAAAG
CAAATGGAGAAGCAATAGTAATAAAAAAATAG

Upstream 100 bases:

>100_bases
GGTTAGAAAATAGAGATATTTTGAACTTAAAAGCGTATGCGCGTATAATGAAAAGATAGATATAGCAACATGTTTTTGCT
AAGAATGGAGGGGGATTAGG

Downstream 100 bases:

>100_bases
TTATTTCTTCTATATAAAAGATAAAAGAAATAACTATTTTTTATTAAGATTTATTGGCTAATGTTTTTTTCATTTCCTTA
TGTTCGATGTTTGCATCAAG

Product: ribose-5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI [H]

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MNQKKIAGEKACGWVKDGMVVGLGTGSTVYYTIEKLGEMVRDGLNITGIATSEETAIQAKKLGIPLKSLNDVKQIDVTID
GADEVNKDFQGIKGGGGALLREKMVAAASLMNIWVVEEKKLVEELGEFSLPIEVIPFGWKQIKWSLEKEAIETELRKNDS
GKVYQTNNGNYILDIKNQILTNPVEWQEKLAGIPGIVEHGLFLDYVDIVICGKANGEAIVIKK

Sequences:

>Translated_223_residues
MNQKKIAGEKACGWVKDGMVVGLGTGSTVYYTIEKLGEMVRDGLNITGIATSEETAIQAKKLGIPLKSLNDVKQIDVTID
GADEVNKDFQGIKGGGGALLREKMVAAASLMNIWVVEEKKLVEELGEFSLPIEVIPFGWKQIKWSLEKEAIETELRKNDS
GKVYQTNNGNYILDIKNQILTNPVEWQEKLAGIPGIVEHGLFLDYVDIVICGKANGEAIVIKK
>Mature_223_residues
MNQKKIAGEKACGWVKDGMVVGLGTGSTVYYTIEKLGEMVRDGLNITGIATSEETAIQAKKLGIPLKSLNDVKQIDVTID
GADEVNKDFQGIKGGGGALLREKMVAAASLMNIWVVEEKKLVEELGEFSLPIEVIPFGWKQIKWSLEKEAIETELRKNDS
GKVYQTNNGNYILDIKNQILTNPVEWQEKLAGIPGIVEHGLFLDYVDIVICGKANGEAIVIKK

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI94536842, Length=222, Percent_Identity=34.2342342342342, Blast_Score=116, Evalue=2e-26,
Organism=Escherichia coli, GI1789280, Length=220, Percent_Identity=35.9090909090909, Blast_Score=132, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17551758, Length=230, Percent_Identity=35.6521739130435, Blast_Score=113, Evalue=7e-26,
Organism=Saccharomyces cerevisiae, GI6324669, Length=221, Percent_Identity=30.316742081448, Blast_Score=99, Evalue=4e-22,
Organism=Drosophila melanogaster, GI281364072, Length=226, Percent_Identity=37.1681415929204, Blast_Score=100, Evalue=7e-22,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR004788
- InterPro:   IPR020672 [H]

Pfam domain/function: PF00455 DeoR; PF06026 Rib_5-P_isom_A [H]

EC number: =5.3.1.6 [H]

Molecular weight: Translated: 24434; Mature: 24434

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQKKIAGEKACGWVKDGMVVGLGTGSTVYYTIEKLGEMVRDGLNITGIATSEETAIQAK
CCCCCCCCCCCCCEECCCEEEEECCCCEEEEEHHHHHHHHHCCCCEEEEECCCHHHHHHH
KLGIPLKSLNDVKQIDVTIDGADEVNKDFQGIKGGGGALLREKMVAAASLMNIWVVEEKK
HHCCCHHHCCCCEEEEEEECCHHHHCHHHCCCCCCCHHHHHHHHHHHHHHHHEEEECHHH
LVEELGEFSLPIEVIPFGWKQIKWSLEKEAIETELRKNDSGKVYQTNNGNYILDIKNQIL
HHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCEEEEECHHHH
TNPVEWQEKLAGIPGIVEHGLFLDYVDIVICGKANGEAIVIKK
CCCHHHHHHHCCCCCHHHCCHHEEEEEEEEECCCCCCEEEEEC
>Mature Secondary Structure
MNQKKIAGEKACGWVKDGMVVGLGTGSTVYYTIEKLGEMVRDGLNITGIATSEETAIQAK
CCCCCCCCCCCCCEECCCEEEEECCCCEEEEEHHHHHHHHHCCCCEEEEECCCHHHHHHH
KLGIPLKSLNDVKQIDVTIDGADEVNKDFQGIKGGGGALLREKMVAAASLMNIWVVEEKK
HHCCCHHHCCCCEEEEEEECCHHHHCHHHCCCCCCCHHHHHHHHHHHHHHHHEEEECHHH
LVEELGEFSLPIEVIPFGWKQIKWSLEKEAIETELRKNDSGKVYQTNNGNYILDIKNQIL
HHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCEEEEECHHHH
TNPVEWQEKLAGIPGIVEHGLFLDYVDIVICGKANGEAIVIKK
CCCHHHHHHHCCCCCHHHCCHHEEEEEEEEECCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]