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The map label for this gene is coaA [H]

Identifier: 116872319

GI number: 116872319

Start: 931710

End: 932630

Strand: Direct

Name: coaA [H]

Synonym: lwe0901

Alternate gene names: 116872319

Gene position: 931710-932630 (Clockwise)

Preceding gene: 116872318

Following gene: 116872320

Centisome position: 33.11

GC content: 35.18

Gene sequence:

>921_bases
ATGAATGATTACAACCACTACTTTCATTTCCCACGAGAAGAATGGCGCAAGCTGGAAGTGAGTAAGGACCAAATTTTAAC
TGCAGAGGAACTGGAAGAAATACGTGGTTTAAATGATCGTATTTCTTTACAAGACATCTCTGAAATTTATTTACCACTAA
TAAAACTAATTGCGATTCAATACCATGAAGCGATTTTTATTCATGGGGAAAAAATGGAATACTTAAAGAAAAAAGAATCA
CGTGCGCCGTTTATCATCGCCTTAGCTGGAAGTGTGGCTGTTGGGAAAAGTACGACAGCGCGTGTGTTCAAATTAATGCT
CGATCGTTGGTTTTCCAAAACAAGGCAAGTGGAGCTTGTAACAACAGACGGTTTTTTATTTCCAAACAAAGTTTTAGAAG
AGCGCGGTATTATGAACAAAAAAGGATTTCCCGAAAGTTATGATCGCGACCGTTTTGCTAAGTTTTTAACTGATTTAAAA
ACAAATAAAGAAGCTGTAGAAGTACCGCTATACTCGCATTTTACATATGATGTTTTAGATGAGACACGTATGATGCATAA
TCCGGATATCGTTATTATTGAAGGAATTAATGTACTTCAAGCCGACCAACACGAGAGTTTATTTCCAAGTGATTTTTTTG
ATTTCTCGGTTTATATGGATGCTGCTGAAGCTGACATTAAGAAATGGTATTTAGAAAGGTTCTTCATGCTTCGAGAAACC
GCTTTTCAAGACAAAAGTTCTTATTTCCACCAATATACTAAAATTAATAAAAAAGAAGCAGAAACGTTTGCTCTAGGGGT
TTGGGATACAATCAATGGAGTTAACTTAAAAGAAAATATTGAGAAAACAAAATATCGAGCAGATTTAGTCCTCCATAAAG
GGACAGATCATCTTATTTCAGACATTTATTTACGAAAATAG

Upstream 100 bases:

>100_bases
CGTAAATATTAAATCGCTACTTGCGGATTTATGCAGCTTGCGTTATCCTTAAATAAAGCTGTTTACGTTTTCACGAATGA
ATAAAAGGATGGAACATTGA

Downstream 100 bases:

>100_bases
CCGAATGCAGATAGAAGGAAACTTCTTGATGCGTTCGGTTTTTCCTTTACAACTAAAAAAAAACTGAGTACAATAGAAAG
TGAGTAATCACTCATTTTTA

Product: pantothenate kinase

Products: NA

Alternate protein names: Pantothenic acid kinase [H]

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MNDYNHYFHFPREEWRKLEVSKDQILTAEELEEIRGLNDRISLQDISEIYLPLIKLIAIQYHEAIFIHGEKMEYLKKKES
RAPFIIALAGSVAVGKSTTARVFKLMLDRWFSKTRQVELVTTDGFLFPNKVLEERGIMNKKGFPESYDRDRFAKFLTDLK
TNKEAVEVPLYSHFTYDVLDETRMMHNPDIVIIEGINVLQADQHESLFPSDFFDFSVYMDAAEADIKKWYLERFFMLRET
AFQDKSSYFHQYTKINKKEAETFALGVWDTINGVNLKENIEKTKYRADLVLHKGTDHLISDIYLRK

Sequences:

>Translated_306_residues
MNDYNHYFHFPREEWRKLEVSKDQILTAEELEEIRGLNDRISLQDISEIYLPLIKLIAIQYHEAIFIHGEKMEYLKKKES
RAPFIIALAGSVAVGKSTTARVFKLMLDRWFSKTRQVELVTTDGFLFPNKVLEERGIMNKKGFPESYDRDRFAKFLTDLK
TNKEAVEVPLYSHFTYDVLDETRMMHNPDIVIIEGINVLQADQHESLFPSDFFDFSVYMDAAEADIKKWYLERFFMLRET
AFQDKSSYFHQYTKINKKEAETFALGVWDTINGVNLKENIEKTKYRADLVLHKGTDHLISDIYLRK
>Mature_306_residues
MNDYNHYFHFPREEWRKLEVSKDQILTAEELEEIRGLNDRISLQDISEIYLPLIKLIAIQYHEAIFIHGEKMEYLKKKES
RAPFIIALAGSVAVGKSTTARVFKLMLDRWFSKTRQVELVTTDGFLFPNKVLEERGIMNKKGFPESYDRDRFAKFLTDLK
TNKEAVEVPLYSHFTYDVLDETRMMHNPDIVIIEGINVLQADQHESLFPSDFFDFSVYMDAAEADIKKWYLERFFMLRET
AFQDKSSYFHQYTKINKKEAETFALGVWDTINGVNLKENIEKTKYRADLVLHKGTDHLISDIYLRK

Specific function: Coenzyme A (CoA) biosynthesis; first step. [C]

COG id: COG1072

COG function: function code H; Panthothenate kinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic pantothenate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1790409, Length=307, Percent_Identity=46.5798045602606, Blast_Score=284, Evalue=4e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004566
- InterPro:   IPR006083 [H]

Pfam domain/function: PF00485 PRK [H]

EC number: =2.7.1.33 [H]

Molecular weight: Translated: 36139; Mature: 36139

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDYNHYFHFPREEWRKLEVSKDQILTAEELEEIRGLNDRISLQDISEIYLPLIKLIAIQ
CCCCCCCCCCCHHHHHHHCCCHHHCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
YHEAIFIHGEKMEYLKKKESRAPFIIALAGSVAVGKSTTARVFKLMLDRWFSKTRQVELV
HHCEEEEECCHHHHHHHHCCCCCEEEEEECCEEECCCHHHHHHHHHHHHHHHHCCEEEEE
TTDGFLFPNKVLEERGIMNKKGFPESYDRDRFAKFLTDLKTNKEAVEVPLYSHFTYDVLD
EECCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEECHHHCCHHHHHH
ETRMMHNPDIVIIEGINVLQADQHESLFPSDFFDFSVYMDAAEADIKKWYLERFFMLRET
HHHHHCCCCEEEECCCCEEECCCCCCCCCCCCCCHHEEECHHHHHHHHHHHHHHHHHHHH
AFQDKSSYFHQYTKINKKEAETFALGVWDTINGVNLKENIEKTKYRADLVLHKGTDHLIS
HHHHHHHHHHHHHHCCHHHHHEEEEEEHHCCCCCCHHHHHHHHHHHHEEEEECCCHHHHH
DIYLRK
HHHCCC
>Mature Secondary Structure
MNDYNHYFHFPREEWRKLEVSKDQILTAEELEEIRGLNDRISLQDISEIYLPLIKLIAIQ
CCCCCCCCCCCHHHHHHHCCCHHHCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
YHEAIFIHGEKMEYLKKKESRAPFIIALAGSVAVGKSTTARVFKLMLDRWFSKTRQVELV
HHCEEEEECCHHHHHHHHCCCCCEEEEEECCEEECCCHHHHHHHHHHHHHHHHCCEEEEE
TTDGFLFPNKVLEERGIMNKKGFPESYDRDRFAKFLTDLKTNKEAVEVPLYSHFTYDVLD
EECCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEECHHHCCHHHHHH
ETRMMHNPDIVIIEGINVLQADQHESLFPSDFFDFSVYMDAAEADIKKWYLERFFMLRET
HHHHHCCCCEEEECCCCEEECCCCCCCCCCCCCCHHEEECHHHHHHHHHHHHHHHHHHHH
AFQDKSSYFHQYTKINKKEAETFALGVWDTINGVNLKENIEKTKYRADLVLHKGTDHLIS
HHHHHHHHHHHHHHCCHHHHHEEEEEEHHCCCCCCHHHHHHHHHHHHEEEEECCCHHHHH
DIYLRK
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]