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The map label for this gene is dhaL [H]

Identifier: 116872224

GI number: 116872224

Start: 833537

End: 834109

Strand: Direct

Name: dhaL [H]

Synonym: lwe0804

Alternate gene names: 116872224

Gene position: 833537-834109 (Clockwise)

Preceding gene: 116872223

Following gene: 116872225

Centisome position: 29.62

GC content: 36.47

Gene sequence:

>573_bases
ATGGTAACTGTAAATTGTGAGTTTATGAAAAATTGGATTTCAGCATGGACGGAAGATTTATTAAACAACACTGATTATTT
AAATGAATTAGATACCCCAATTGGTGATGATGATCATGGAACCAATATGGAACGTGGAGCAATAGCGGTGCGAGAAGTAT
TGACACAGGAGTTTGATAATCCACAAGAATTAACTAAAAAAATTGCTATGGCTTTACTCACGAAGGTTGGAGGAGCTTCA
GGTGTTATTTATGGAACTGCTTTTTTGGAAATGAGTAAAGAAACAGAGTTATCCTCTATGATTAATGCTGGACTTTCTGG
AATAGTAAAGCGTGGCAAAGCTGAAGCGGGTGATAAGACACTCCTAGATGTTTGGATTCCTGTATCAGATTTTATCAAAC
AAAAATCTTTAACGGATGAACAAATTCAAGATGCCGTAGAGGCAACAAAACCTATGCTTGCTAAAAAAGGTCGTGCAGAA
TTTGTGGGAGAGCAATCTATTGGACATATTGATCCAGGTTCAGTATCTAGCGGTTATTTATTTAAAGCTCTAGCCAAAGA
GGTAAATAAATGA

Upstream 100 bases:

>100_bases
GTACGGTTCTAACAGCTTTTGGTACGGGTCCATTTATCGGTTTCTTTAATAAAACAATATCAGCTTGGATTGTTGGTAAA
GGTAATAAGGAGGCTGAGTG

Downstream 100 bases:

>100_bases
GTCAGTATGGTATTGTGATTGTTTCCCATGTCCCTGAAATTACATCAGGAATAAAGCGTTTAATCGAACAAGTGGCAAGC
AATGTATGTGTGACTATTGC

Product: dihydroxyacetone kinase family protein

Products: ADP; glycerone phosphate

Alternate protein names: NA

Number of amino acids: Translated: 190; Mature: 190

Protein sequence:

>190_residues
MVTVNCEFMKNWISAWTEDLLNNTDYLNELDTPIGDDDHGTNMERGAIAVREVLTQEFDNPQELTKKIAMALLTKVGGAS
GVIYGTAFLEMSKETELSSMINAGLSGIVKRGKAEAGDKTLLDVWIPVSDFIKQKSLTDEQIQDAVEATKPMLAKKGRAE
FVGEQSIGHIDPGSVSSGYLFKALAKEVNK

Sequences:

>Translated_190_residues
MVTVNCEFMKNWISAWTEDLLNNTDYLNELDTPIGDDDHGTNMERGAIAVREVLTQEFDNPQELTKKIAMALLTKVGGAS
GVIYGTAFLEMSKETELSSMINAGLSGIVKRGKAEAGDKTLLDVWIPVSDFIKQKSLTDEQIQDAVEATKPMLAKKGRAE
FVGEQSIGHIDPGSVSSGYLFKALAKEVNK
>Mature_190_residues
MVTVNCEFMKNWISAWTEDLLNNTDYLNELDTPIGDDDHGTNMERGAIAVREVLTQEFDNPQELTKKIAMALLTKVGGAS
GVIYGTAFLEMSKETELSSMINAGLSGIVKRGKAEAGDKTLLDVWIPVSDFIKQKSLTDEQIQDAVEATKPMLAKKGRAE
FVGEQSIGHIDPGSVSSGYLFKALAKEVNK

Specific function: ADP-binding subunit of the dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone [H]

COG id: COG2376

COG function: function code G; Dihydroxyacetone kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DhaL domain [H]

Homologues:

Organism=Homo sapiens, GI20149621, Length=174, Percent_Identity=34.4827586206897, Blast_Score=75, Evalue=4e-14,
Organism=Escherichia coli, GI1787449, Length=196, Percent_Identity=38.265306122449, Blast_Score=128, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004007
- InterPro:   IPR012737 [H]

Pfam domain/function: PF02734 Dak2 [H]

EC number: 2.7.1.29

Molecular weight: Translated: 20744; Mature: 20744

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTVNCEFMKNWISAWTEDLLNNTDYLNELDTPIGDDDHGTNMERGAIAVREVLTQEFDN
CEEECHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCC
PQELTKKIAMALLTKVGGASGVIYGTAFLEMSKETELSSMINAGLSGIVKRGKAEAGDKT
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
LLDVWIPVSDFIKQKSLTDEQIQDAVEATKPMLAKKGRAEFVGEQSIGHIDPGSVSSGYL
HHHEECCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCHHH
FKALAKEVNK
HHHHHHHHCC
>Mature Secondary Structure
MVTVNCEFMKNWISAWTEDLLNNTDYLNELDTPIGDDDHGTNMERGAIAVREVLTQEFDN
CEEECHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCC
PQELTKKIAMALLTKVGGASGVIYGTAFLEMSKETELSSMINAGLSGIVKRGKAEAGDKT
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
LLDVWIPVSDFIKQKSLTDEQIQDAVEATKPMLAKKGRAEFVGEQSIGHIDPGSVSSGYL
HHHEECCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCHHH
FKALAKEVNK
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; glycerone

Specific reaction: ATP + glycerone = ADP + glycerone phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]