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The map label for this gene is dhaK [H]

Identifier: 116872222

GI number: 116872222

Start: 831877

End: 832845

Strand: Direct

Name: dhaK [H]

Synonym: lwe0802

Alternate gene names: 116872222

Gene position: 831877-832845 (Clockwise)

Preceding gene: 116872221

Following gene: 116872223

Centisome position: 29.56

GC content: 31.48

Gene sequence:

>969_bases
GTGCTTAATAAATTACGTAACCGCCATGTATTGATTGATAACACAGAAGATATAATTAAAAAAGAATTGCTTGGAATTAT
TAAAACAAGACCTAACTATTATGAATTAGTAGATGATGAATATGGTTTTGGCTTAATGTTAAAAAATCTGAATCAAGATA
AAGTTGGCGTTATAGCTTCAGGAGGCGGTGGTTTAGGTCGTTTATTTCCCGCTGTGGTACATGAAAATTTAGCTGATGCA
GTAAGCGCAGGAGAGATGGATACTGCCCCTAATTATTTTACTATTTATAATTTAGCTAAAAAAATTAATACAGGTAAAGG
TGTTATTCTTTTGACAAACAACTATAGCGGAGATGTCATGAATAATGAAATGGCCCAAGAAATGCTTGAAGCAGATGGAA
TTCCTGCAACCATTTGTAAAGTAACAGATAATTTCTTTAGTTCTAAGGAAAAAAACAAACGATCAGGTTTGTCTGGAATT
TTGACACTGATTAAAATTGCTCAAGCAGCTGCAAAAAAAGGATTAGACTTAAAGGAAGTTACGAGAATTGTTGAAAATGC
GAATCAAAAACTAATTTCTGTAACTGTAATGGCTAGTGAAGAAGGCGTTCTTATGTATGGCAAAGGACTAGCTGATGAGC
CCGCTAAATTTACTAGTGATTTTTCAGGTGAAAACGATTTGATTAAAGAACTTAGTAATTTTGTCATTGAGCAGATAAAA
GAAGATTCTACTAATAAAATTTCCATTCAATTAAATACAATGAAATATACTTCTTATATTGAAGGCAATGTTTTACTAAA
TGGGATAATGGATTATTTTTCTAATGAAGGATTCGATGTTGTTTTAGCTAATGTAGGTGGATATTATGACATGTTTAACT
ATCCAGGAGTAATTTTAACAGTATTATCAGTAGATGAACAGACACTAGAATTTATCAAACCTGTCACAAATTATGATTAC
ACAATATAG

Upstream 100 bases:

>100_bases
GTTGGTATTCAGATATTCTTAGGATTAGTTTAAAATAGCTATAAATTCTTATAGAATAGAATATTGTAAGCGCAATAAAA
ATTAAAAAGGAGGAATTATA

Downstream 100 bases:

>100_bases
AAAAAGGAGAGATTAATATGAATTTAAATAAATACAATTTTCGTAGCATATTTTCATCAGCTTTAGGAATAATCATTTTA
TCATTAGGGATTTCTATTAA

Product: dihydroxyacetone kinase, putative

Products: ADP; glycerone phosphate

Alternate protein names: NA

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MLNKLRNRHVLIDNTEDIIKKELLGIIKTRPNYYELVDDEYGFGLMLKNLNQDKVGVIASGGGGLGRLFPAVVHENLADA
VSAGEMDTAPNYFTIYNLAKKINTGKGVILLTNNYSGDVMNNEMAQEMLEADGIPATICKVTDNFFSSKEKNKRSGLSGI
LTLIKIAQAAAKKGLDLKEVTRIVENANQKLISVTVMASEEGVLMYGKGLADEPAKFTSDFSGENDLIKELSNFVIEQIK
EDSTNKISIQLNTMKYTSYIEGNVLLNGIMDYFSNEGFDVVLANVGGYYDMFNYPGVILTVLSVDEQTLEFIKPVTNYDY
TI

Sequences:

>Translated_322_residues
MLNKLRNRHVLIDNTEDIIKKELLGIIKTRPNYYELVDDEYGFGLMLKNLNQDKVGVIASGGGGLGRLFPAVVHENLADA
VSAGEMDTAPNYFTIYNLAKKINTGKGVILLTNNYSGDVMNNEMAQEMLEADGIPATICKVTDNFFSSKEKNKRSGLSGI
LTLIKIAQAAAKKGLDLKEVTRIVENANQKLISVTVMASEEGVLMYGKGLADEPAKFTSDFSGENDLIKELSNFVIEQIK
EDSTNKISIQLNTMKYTSYIEGNVLLNGIMDYFSNEGFDVVLANVGGYYDMFNYPGVILTVLSVDEQTLEFIKPVTNYDY
TI
>Mature_322_residues
MLNKLRNRHVLIDNTEDIIKKELLGIIKTRPNYYELVDDEYGFGLMLKNLNQDKVGVIASGGGGLGRLFPAVVHENLADA
VSAGEMDTAPNYFTIYNLAKKINTGKGVILLTNNYSGDVMNNEMAQEMLEADGIPATICKVTDNFFSSKEKNKRSGLSGI
LTLIKIAQAAAKKGLDLKEVTRIVENANQKLISVTVMASEEGVLMYGKGLADEPAKFTSDFSGENDLIKELSNFVIEQIK
EDSTNKISIQLNTMKYTSYIEGNVLLNGIMDYFSNEGFDVVLANVGGYYDMFNYPGVILTVLSVDEQTLEFIKPVTNYDY
TI

Specific function: Dihydroxyacetone binding subunit of the dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone [H]

COG id: COG2376

COG function: function code G; Dihydroxyacetone kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DhaK domain [H]

Homologues:

Organism=Homo sapiens, GI20149621, Length=323, Percent_Identity=21.671826625387, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI87081857, Length=341, Percent_Identity=21.7008797653959, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17565018, Length=318, Percent_Identity=25.1572327044025, Blast_Score=78, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6321055, Length=196, Percent_Identity=29.0816326530612, Blast_Score=82, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004006
- InterPro:   IPR012736 [H]

Pfam domain/function: PF02733 Dak1 [H]

EC number: 2.7.1.29

Molecular weight: Translated: 35585; Mature: 35585

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNKLRNRHVLIDNTEDIIKKELLGIIKTRPNYYELVDDEYGFGLMLKNLNQDKVGVIAS
CCCCCCCCEEEEECHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCEEECCCCCCEEEEEE
GGGGLGRLFPAVVHENLADAVSAGEMDTAPNYFTIYNLAKKINTGKGVILLTNNYSGDVM
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHCCCCCEEEEEECCCCCCCC
NNEMAQEMLEADGIPATICKVTDNFFSSKEKNKRSGLSGILTLIKIAQAAAKKGLDLKEV
CHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
TRIVENANQKLISVTVMASEEGVLMYGKGLADEPAKFTSDFSGENDLIKELSNFVIEQIK
HHHHHCCCCEEEEEEEEECCCCEEEECCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHH
EDSTNKISIQLNTMKYTSYIEGNVLLNGIMDYFSNEGFDVVLANVGGYYDMFNYPGVILT
CCCCCEEEEEEEEEEEEEEECCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHCCCCEEEE
VLSVDEQTLEFIKPVTNYDYTI
EECCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLNKLRNRHVLIDNTEDIIKKELLGIIKTRPNYYELVDDEYGFGLMLKNLNQDKVGVIAS
CCCCCCCCEEEEECHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCEEECCCCCCEEEEEE
GGGGLGRLFPAVVHENLADAVSAGEMDTAPNYFTIYNLAKKINTGKGVILLTNNYSGDVM
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHCCCCCEEEEEECCCCCCCC
NNEMAQEMLEADGIPATICKVTDNFFSSKEKNKRSGLSGILTLIKIAQAAAKKGLDLKEV
CHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
TRIVENANQKLISVTVMASEEGVLMYGKGLADEPAKFTSDFSGENDLIKELSNFVIEQIK
HHHHHCCCCEEEEEEEEECCCCEEEECCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHH
EDSTNKISIQLNTMKYTSYIEGNVLLNGIMDYFSNEGFDVVLANVGGYYDMFNYPGVILT
CCCCCEEEEEEEEEEEEEEECCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHCCCCEEEE
VLSVDEQTLEFIKPVTNYDYTI
EECCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; glycerone

Specific reaction: ATP + glycerone = ADP + glycerone phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]