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The map label for this gene is map [H]

Identifier: 116690041

GI number: 116690041

Start: 2236744

End: 2237559

Strand: Direct

Name: map [H]

Synonym: Bcen2424_2020

Alternate gene names: 116690041

Gene position: 2236744-2237559 (Clockwise)

Preceding gene: 116690024

Following gene: 116690042

Centisome position: 64.2

GC content: 65.07

Gene sequence:

>816_bases
ATGGCTATTACGCTCAAAAACGAACACGATATCGCGGAGATGCGCGTCGCCTGCCGTCTCGCCAGCGAAGTGCTCGACTT
CATCACGCCGCACGTCGTCGCGGGCGTCACGACCGCCGAACTCGACCGCCTCTGCCACGAGTTCATGCTCAACGAGCAAG
GCACGATCCCCGCGCCGCTGAACTACCAGCCGCCCGGCTATCCGCCGTACCCGAAGGCCACCTGCATTTCGGTCAACGAC
GTGATCTGCCACGGCATTCCCGGCGAGAAGGTGATCAAGAACGGCGACGCGCTGAACATCGACATCACCGTGATCAAGAA
CGGCTACTTCGGCGACACCAGCCGGATGTTCATCGTCGGCGAGGGTTCGATCCTCGCGAAGCGCCTCGTGCAGACCACCT
ACGAATGCATGTGGCTCGGCATCGACCAGGTCAAGCCCGGCGCGCACCTCGGCGACATCGGCTACGCGATCCAGAAGCAC
GCGGAGGCGCAGGGCTACAGCGTCGTGCGCGAATACTGCGGCCATGGCATCGGCACGGTGTTCCACGAGGACCCGCAGGT
CGTCCACTACGGTCGCCCGGGCACCGGTATCGAACTGAAGGCCGGGATGATCTTCACGATCGAGCCGATGATCAACGCCG
GCAAGCGCGACATCCGCACGATGCCCGACCAGTGGACGGTCAAGACGCGCGACCGCAGCCTGTCCGCGCAATGGGAGCAC
ACGGTGCTCGTCACCGAAACCGGCTACGAGGTGCTGACCGTGTCGGCCGGCACGCCGGCGCGCCCCGTGTTCGCGCAATC
GGCCGCCGCCGTCTGA

Upstream 100 bases:

>100_bases
ACAATCCGCGAAAACCCGCATCCGCGCGGCCGGCAGGGGCTGCGAGGCCCGCCATAAGGTGCGATAATCCGTCAATTCAC
CGCATTCCAGGCATACCTCG

Downstream 100 bases:

>100_bases
GCGCCGTCGCGCCAGCCCGCCCCACCCCGCACCTGAACGGCCGCCCATGAGCGCTCACGCTGCCCCCTCGCCCGAAGCGC
TGTCGCGGCGCGCCGAATTC

Product: methionine aminopeptidase

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 271; Mature: 270

Protein sequence:

>271_residues
MAITLKNEHDIAEMRVACRLASEVLDFITPHVVAGVTTAELDRLCHEFMLNEQGTIPAPLNYQPPGYPPYPKATCISVND
VICHGIPGEKVIKNGDALNIDITVIKNGYFGDTSRMFIVGEGSILAKRLVQTTYECMWLGIDQVKPGAHLGDIGYAIQKH
AEAQGYSVVREYCGHGIGTVFHEDPQVVHYGRPGTGIELKAGMIFTIEPMINAGKRDIRTMPDQWTVKTRDRSLSAQWEH
TVLVTETGYEVLTVSAGTPARPVFAQSAAAV

Sequences:

>Translated_271_residues
MAITLKNEHDIAEMRVACRLASEVLDFITPHVVAGVTTAELDRLCHEFMLNEQGTIPAPLNYQPPGYPPYPKATCISVND
VICHGIPGEKVIKNGDALNIDITVIKNGYFGDTSRMFIVGEGSILAKRLVQTTYECMWLGIDQVKPGAHLGDIGYAIQKH
AEAQGYSVVREYCGHGIGTVFHEDPQVVHYGRPGTGIELKAGMIFTIEPMINAGKRDIRTMPDQWTVKTRDRSLSAQWEH
TVLVTETGYEVLTVSAGTPARPVFAQSAAAV
>Mature_270_residues
AITLKNEHDIAEMRVACRLASEVLDFITPHVVAGVTTAELDRLCHEFMLNEQGTIPAPLNYQPPGYPPYPKATCISVNDV
ICHGIPGEKVIKNGDALNIDITVIKNGYFGDTSRMFIVGEGSILAKRLVQTTYECMWLGIDQVKPGAHLGDIGYAIQKHA
EAQGYSVVREYCGHGIGTVFHEDPQVVHYGRPGTGIELKAGMIFTIEPMINAGKRDIRTMPDQWTVKTRDRSLSAQWEHT
VLVTETGYEVLTVSAGTPARPVFAQSAAAV

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI164420681, Length=262, Percent_Identity=49.236641221374, Blast_Score=244, Evalue=7e-65,
Organism=Homo sapiens, GI40385867, Length=252, Percent_Identity=38.8888888888889, Blast_Score=186, Evalue=3e-47,
Organism=Escherichia coli, GI1786364, Length=255, Percent_Identity=58.4313725490196, Blast_Score=313, Evalue=6e-87,
Organism=Escherichia coli, GI1788728, Length=254, Percent_Identity=25.1968503937008, Blast_Score=66, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71996291, Length=252, Percent_Identity=46.8253968253968, Blast_Score=221, Evalue=2e-58,
Organism=Saccharomyces cerevisiae, GI6323273, Length=262, Percent_Identity=44.2748091603053, Blast_Score=220, Evalue=2e-58,
Organism=Drosophila melanogaster, GI21355531, Length=262, Percent_Identity=45.8015267175573, Blast_Score=219, Evalue=1e-57,
Organism=Drosophila melanogaster, GI24583427, Length=249, Percent_Identity=37.7510040160643, Blast_Score=180, Evalue=8e-46,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 29649; Mature: 29518

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS00680 MAP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAITLKNEHDIAEMRVACRLASEVLDFITPHVVAGVTTAELDRLCHEFMLNEQGTIPAPL
CEEEECCCCCHHHHHHHHHHHHHHHHHHCHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCC
NYQPPGYPPYPKATCISVNDVICHGIPGEKVIKNGDALNIDITVIKNGYFGDTSRMFIVG
CCCCCCCCCCCCEEEEEECCEEEECCCCHHHHCCCCEEEEEEEEEECCCCCCCCEEEEEE
EGSILAKRLVQTTYECMWLGIDQVKPGAHLGDIGYAIQKHAEAQGYSVVREYCGHGIGTV
CCHHHHHHHHHHHHHHEEEEHHHCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCEE
FHEDPQVVHYGRPGTGIELKAGMIFTIEPMINAGKRDIRTMPDQWTVKTRDRSLSAQWEH
EECCCCEEEECCCCCCEEEECCEEEEEECCCCCCCHHHHCCCCCEEEEECCCCCCCCCCE
TVLVTETGYEVLTVSAGTPARPVFAQSAAAV
EEEEEECCCEEEEEECCCCCCCHHHHHCCCC
>Mature Secondary Structure 
AITLKNEHDIAEMRVACRLASEVLDFITPHVVAGVTTAELDRLCHEFMLNEQGTIPAPL
EEEECCCCCHHHHHHHHHHHHHHHHHHCHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCC
NYQPPGYPPYPKATCISVNDVICHGIPGEKVIKNGDALNIDITVIKNGYFGDTSRMFIVG
CCCCCCCCCCCCEEEEEECCEEEECCCCHHHHCCCCEEEEEEEEEECCCCCCCCEEEEEE
EGSILAKRLVQTTYECMWLGIDQVKPGAHLGDIGYAIQKHAEAQGYSVVREYCGHGIGTV
CCHHHHHHHHHHHHHHEEEEHHHCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCEE
FHEDPQVVHYGRPGTGIELKAGMIFTIEPMINAGKRDIRTMPDQWTVKTRDRSLSAQWEH
EECCCCEEEECCCCCCEEEECCEEEEEECCCCCCCHHHHCCCCCEEEEECCCCCCCCCCE
TVLVTETGYEVLTVSAGTPARPVFAQSAAAV
EEEEEECCCEEEEEECCCCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]