Click here to switch to the map view.

The map label for this gene is ompR [H]

Identifier: 116689959

GI number: 116689959

Start: 2154283

End: 2155017

Strand: Direct

Name: ompR [H]

Synonym: Bcen2424_1938

Alternate gene names: 116689959

Gene position: 2154283-2155017 (Clockwise)

Preceding gene: 116689955

Following gene: 116689960

Centisome position: 61.84

GC content: 65.58

Gene sequence:

>735_bases
ATGCCGATCATGGAAACGAAAAACCCCTCCAAGATTCTCGTCGTCGACGACGACCCTCGCCTGCGCGATCTGCTGCGCCG
CTATCTCGGCGAACAGGGTTTCAACGTCTACGTCGCGGAAAACGCGACCGCGATGAACAAGCTCTGGGTGCGCGAGCGTT
TCGACCTGCTCGTGCTCGACCTGATGCTGCCCGGCGAGGACGGCCTGTCGATCTGCCGCCGGCTGCGCGGCAGCAACGAC
CGCACGCCGATCATCATGCTCACCGCGAAGGGCGAGGACGTCGATCGCATCGTCGGCCTCGAGATGGGCGCCGACGATTA
CCTGCCGAAGCCGTTCAACCCGCGCGAACTGGTCGCGCGCATTCACGCGGTGCTGCGCCGCCAGGCGCCGGCCGAACTGC
CGGGCGCCCCGTCGGAAACCACCGAGGTGTTCGAGTTCGGCGAATTCTCGCTGAATCTCGCCACGCGCACGCTGACGAAA
TCCGGCCAGGAAATTCCGCTGACCACCGGCGAATTCTCGGTGCTGAAAGTGTTCGCGCGTCATCCGCGCCAGCCGCTGTC
GCGTGAAAAGCTGATGGAGCTCGCCCGCGGCCGCGAATACGAAGTGTTCGACCGCAGCCTCGACGTGCAGATCTCGCGCC
TGCGCAAGCTGATCGAACCCGATCCGGGCAGCCCGCGCTTCATCCAGACCGTCTGGGGCCTCGGCTACGTGTTCATCCCG
GACGGCGCCGCCTGA

Upstream 100 bases:

>100_bases
ATAGCCTGCCTTTACTCGGCGCGACACTACGGGTAAATTTTGTAACCGACTGTAACGCACGAAAATCCCCGGCCGTGCGT
CAATTCCCATTCGCGATAAG

Downstream 100 bases:

>100_bases
GCTTTTTCCTTCCCGGCTTCGCCCCGTCCACGGCCCGTCCCATGCGTATCGACCGGCGCCTTTTGCAGCTCGCGTTCGGC
GGGCTGTTCTGGCGCACCTT

Product: osmolarity response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 244; Mature: 243

Protein sequence:

>244_residues
MPIMETKNPSKILVVDDDPRLRDLLRRYLGEQGFNVYVAENATAMNKLWVRERFDLLVLDLMLPGEDGLSICRRLRGSND
RTPIIMLTAKGEDVDRIVGLEMGADDYLPKPFNPRELVARIHAVLRRQAPAELPGAPSETTEVFEFGEFSLNLATRTLTK
SGQEIPLTTGEFSVLKVFARHPRQPLSREKLMELARGREYEVFDRSLDVQISRLRKLIEPDPGSPRFIQTVWGLGYVFIP
DGAA

Sequences:

>Translated_244_residues
MPIMETKNPSKILVVDDDPRLRDLLRRYLGEQGFNVYVAENATAMNKLWVRERFDLLVLDLMLPGEDGLSICRRLRGSND
RTPIIMLTAKGEDVDRIVGLEMGADDYLPKPFNPRELVARIHAVLRRQAPAELPGAPSETTEVFEFGEFSLNLATRTLTK
SGQEIPLTTGEFSVLKVFARHPRQPLSREKLMELARGREYEVFDRSLDVQISRLRKLIEPDPGSPRFIQTVWGLGYVFIP
DGAA
>Mature_243_residues
PIMETKNPSKILVVDDDPRLRDLLRRYLGEQGFNVYVAENATAMNKLWVRERFDLLVLDLMLPGEDGLSICRRLRGSNDR
TPIIMLTAKGEDVDRIVGLEMGADDYLPKPFNPRELVARIHAVLRRQAPAELPGAPSETTEVFEFGEFSLNLATRTLTKS
GQEIPLTTGEFSVLKVFARHPRQPLSREKLMELARGREYEVFDRSLDVQISRLRKLIEPDPGSPRFIQTVWGLGYVFIPD
GAA

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=233, Percent_Identity=68.6695278969957, Blast_Score=329, Evalue=1e-91,
Organism=Escherichia coli, GI2367329, Length=231, Percent_Identity=42.8571428571429, Blast_Score=154, Evalue=5e-39,
Organism=Escherichia coli, GI1786599, Length=234, Percent_Identity=41.4529914529915, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI1788394, Length=244, Percent_Identity=37.2950819672131, Blast_Score=151, Evalue=4e-38,
Organism=Escherichia coli, GI1786784, Length=233, Percent_Identity=38.1974248927039, Blast_Score=151, Evalue=4e-38,
Organism=Escherichia coli, GI1790863, Length=232, Percent_Identity=34.051724137931, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI1787229, Length=234, Percent_Identity=35.4700854700855, Blast_Score=139, Evalue=1e-34,
Organism=Escherichia coli, GI145693140, Length=235, Percent_Identity=37.0212765957447, Blast_Score=138, Evalue=4e-34,
Organism=Escherichia coli, GI1790860, Length=228, Percent_Identity=34.6491228070175, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI1786911, Length=230, Percent_Identity=32.6086956521739, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI87082012, Length=230, Percent_Identity=30.4347826086957, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1787375, Length=232, Percent_Identity=33.1896551724138, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI1789402, Length=228, Percent_Identity=31.140350877193, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1790552, Length=234, Percent_Identity=34.1880341880342, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1788550, Length=120, Percent_Identity=31.6666666666667, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1790299, Length=110, Percent_Identity=32.7272727272727, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788905, Length=126, Percent_Identity=31.7460317460317, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27677; Mature: 27546

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIMETKNPSKILVVDDDPRLRDLLRRYLGEQGFNVYVAENATAMNKLWVRERFDLLVLD
CCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHCEEEEE
LMLPGEDGLSICRRLRGSNDRTPIIMLTAKGEDVDRIVGLEMGADDYLPKPFNPRELVAR
EECCCCHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHEEEECCCCCCCCCCCCHHHHHHH
IHAVLRRQAPAELPGAPSETTEVFEFGEFSLNLATRTLTKSGQEIPLTTGEFSVLKVFAR
HHHHHHHCCCCCCCCCCCCHHHHHHHCCEEEHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
HPRQPLSREKLMELARGREYEVFDRSLDVQISRLRKLIEPDPGSPRFIQTVWGLGYVFIP
CCCCCCCHHHHHHHHCCCCEEEHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHCCCEEEEC
DGAA
CCCC
>Mature Secondary Structure 
PIMETKNPSKILVVDDDPRLRDLLRRYLGEQGFNVYVAENATAMNKLWVRERFDLLVLD
CCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHCEEEEE
LMLPGEDGLSICRRLRGSNDRTPIIMLTAKGEDVDRIVGLEMGADDYLPKPFNPRELVAR
EECCCCHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHEEEECCCCCCCCCCCCHHHHHHH
IHAVLRRQAPAELPGAPSETTEVFEFGEFSLNLATRTLTKSGQEIPLTTGEFSVLKVFAR
HHHHHHHCCCCCCCCCCCCHHHHHHHCCEEEHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
HPRQPLSREKLMELARGREYEVFDRSLDVQISRLRKLIEPDPGSPRFIQTVWGLGYVFIP
CCCCCCCHHHHHHHHCCCCEEEHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHCCCEEEEC
DGAA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]