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The map label for this gene is pgi [H]

Identifier: 116689938

GI number: 116689938

Start: 2128489

End: 2130159

Strand: Direct

Name: pgi [H]

Synonym: Bcen2424_1917

Alternate gene names: 116689938

Gene position: 2128489-2130159 (Clockwise)

Preceding gene: 116689937

Following gene: 116689940

Centisome position: 61.09

GC content: 67.32

Gene sequence:

>1671_bases
ATGAGCCGGCGCGGCATTCCTCCCGATTCACGCTTCACTCGAACCGCCATGACGCTGAAATCGCTCCCCGCCTGGACTGC
CCTTCAATCCCACTTCGAACAGATCCGCCACGCGCGGCTGCGCGACTGGTTCGCGCCGGAAAACGATCGCGCGCCGACCC
GCGCCGAACGCTTCACGATTCCGGGCGGCGGTCTCGCGGCCGATTTCTCGAAGAATCGCATCGACGACGAAACGCTGCGC
CTGCTCGTGCAGCTCGCGCGCGACGCCGGCGTCGAGGCGCGCCGCGACGCGATGTTCGCGGGCGAGATCGTCAACCCGAC
CGAAGGCCGCGCCGCGCTGCACACCGCGCTGCGCGCGACCGACCCGCAAGCGCCGTTCCATGCGCAGGTGAGCGCCGAGC
GCGCGAAGATGGCGACGTTCGCGCGCGCCGTGCGCAGCGGCACGTGGACGGGCTATACGGGCAAGCGCATTCGCCACGTG
ATCAACATCGGCATCGGCGGCTCCGATCTCGGCCCGAAGATGGTCGTGCATGCGCTGCACCACGTCGCGACGCCCGAGAT
CTCGACGCACTTCGTGTCGAACGTCGACGGCGCCGATCTCGCGCGCGTGCTCGAACAGGTCGATCCCGAGGAAACGCTCG
CGATCATCGTGTCGAAGACCTTCACGACGCTCGAGACGATGACGAACGCACGCTCGCTGCGCGACTGGTTCGTCGCGCGC
GGCTGCCCCGAGGATGCGCTCGCGAAGCACTTCGTCGGCGTGTCGGCGAACCCGGCCGAAGTCGTGAAGTTCGGCATCGC
CGCGGACAACGTGTTCGAAATGTGGGACTGGGTCGGCGGCCGCTATTCGCTGTGGTCGGCGGTCGGCCTGTCGATCATGA
TCGCGATCGGCCCCGAACAGTTCGACGAACTGCTGGCCGGCGCGAACGACATGGACCGCCACTTCCGCGAAGCGCCGCTC
GAGCGCAACCTCCCGGTGCTGCTCGGCCTGATCGGCATCTGGTACCGGAATTTCTTCGGCTCGCAGAGCTATCTCGTCGC
GCCGTATTCGGAAGCGCTGCACTACCTGCCGTCTTACCTGCAGCAGCTCGAAATGGAGAGCAACGGCAAATCCGCGCGCC
TCGACGGCACCTTCGTCGACTACCCGACGTCGGCCGTCACGTGGGGTGAGCCGGGCACCAACGGCCAGCATGCGTTCTTC
CAGATGCTGCACCAGGGGCCGACGATCGTGCCGATCGACTTCATCGCGGTGCTGACGCCCGAACATCCGCTCGCGGGCCA
TCATCCGAAGCTGCTCGCGAACTGCTTCGCGCAGAGCGAAGCGCTGATGCTCGGCCGCACGCTCGAGGAAGCGCGCAAGG
TCGCCGGGCCCGGCAAGGAAGCGCTCGCGCCGCACCTGACGTTCCCCGGCAACCGCCCGACCACGACGCTGCTCGTCGAT
GCGCTGACACCGCGCACGCTCGGCGCGTTGATCGCGCTTTACGAGCACAAGGTGCTCGTGCAGGCGACGGTGTGGGACAT
CAATCCGTTCGACCAGTGGGGCGTCGAGCTCGGCAAGATTCTCGGCAAGGTGGTCGAAGGCGACCTGTCGGCCGAATCGG
TCGATCCGGCGAAGCACGACTCGTCGACCACGGCGCTGATCGAGCGCGCCCGCGCGGCACTCAAGCGTTGA

Upstream 100 bases:

>100_bases
TCGCCTTTTTTACCCGTCGCCGCGCGCCGACACGTAACGCCGCTATACTGACTGCCCCGCCGCACGGCGGGCCTTCTCGT
CCGCCGGCTTTCCGATCCCG

Downstream 100 bases:

>100_bases
CGCGCTGACGCGACGGCGTCATGCCCGTGCCGGCCGTGCGATTGACGCCGCGCGGCCGGCACGACCATTCACGCGTTGCG
CGATGCCGCGTGCGGCGCGA

Product: glucose-6-phosphate isomerase

Products: NA

Alternate protein names: GPI; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHI [H]

Number of amino acids: Translated: 556; Mature: 555

Protein sequence:

>556_residues
MSRRGIPPDSRFTRTAMTLKSLPAWTALQSHFEQIRHARLRDWFAPENDRAPTRAERFTIPGGGLAADFSKNRIDDETLR
LLVQLARDAGVEARRDAMFAGEIVNPTEGRAALHTALRATDPQAPFHAQVSAERAKMATFARAVRSGTWTGYTGKRIRHV
INIGIGGSDLGPKMVVHALHHVATPEISTHFVSNVDGADLARVLEQVDPEETLAIIVSKTFTTLETMTNARSLRDWFVAR
GCPEDALAKHFVGVSANPAEVVKFGIAADNVFEMWDWVGGRYSLWSAVGLSIMIAIGPEQFDELLAGANDMDRHFREAPL
ERNLPVLLGLIGIWYRNFFGSQSYLVAPYSEALHYLPSYLQQLEMESNGKSARLDGTFVDYPTSAVTWGEPGTNGQHAFF
QMLHQGPTIVPIDFIAVLTPEHPLAGHHPKLLANCFAQSEALMLGRTLEEARKVAGPGKEALAPHLTFPGNRPTTTLLVD
ALTPRTLGALIALYEHKVLVQATVWDINPFDQWGVELGKILGKVVEGDLSAESVDPAKHDSSTTALIERARAALKR

Sequences:

>Translated_556_residues
MSRRGIPPDSRFTRTAMTLKSLPAWTALQSHFEQIRHARLRDWFAPENDRAPTRAERFTIPGGGLAADFSKNRIDDETLR
LLVQLARDAGVEARRDAMFAGEIVNPTEGRAALHTALRATDPQAPFHAQVSAERAKMATFARAVRSGTWTGYTGKRIRHV
INIGIGGSDLGPKMVVHALHHVATPEISTHFVSNVDGADLARVLEQVDPEETLAIIVSKTFTTLETMTNARSLRDWFVAR
GCPEDALAKHFVGVSANPAEVVKFGIAADNVFEMWDWVGGRYSLWSAVGLSIMIAIGPEQFDELLAGANDMDRHFREAPL
ERNLPVLLGLIGIWYRNFFGSQSYLVAPYSEALHYLPSYLQQLEMESNGKSARLDGTFVDYPTSAVTWGEPGTNGQHAFF
QMLHQGPTIVPIDFIAVLTPEHPLAGHHPKLLANCFAQSEALMLGRTLEEARKVAGPGKEALAPHLTFPGNRPTTTLLVD
ALTPRTLGALIALYEHKVLVQATVWDINPFDQWGVELGKILGKVVEGDLSAESVDPAKHDSSTTALIERARAALKR
>Mature_555_residues
SRRGIPPDSRFTRTAMTLKSLPAWTALQSHFEQIRHARLRDWFAPENDRAPTRAERFTIPGGGLAADFSKNRIDDETLRL
LVQLARDAGVEARRDAMFAGEIVNPTEGRAALHTALRATDPQAPFHAQVSAERAKMATFARAVRSGTWTGYTGKRIRHVI
NIGIGGSDLGPKMVVHALHHVATPEISTHFVSNVDGADLARVLEQVDPEETLAIIVSKTFTTLETMTNARSLRDWFVARG
CPEDALAKHFVGVSANPAEVVKFGIAADNVFEMWDWVGGRYSLWSAVGLSIMIAIGPEQFDELLAGANDMDRHFREAPLE
RNLPVLLGLIGIWYRNFFGSQSYLVAPYSEALHYLPSYLQQLEMESNGKSARLDGTFVDYPTSAVTWGEPGTNGQHAFFQ
MLHQGPTIVPIDFIAVLTPEHPLAGHHPKLLANCFAQSEALMLGRTLEEARKVAGPGKEALAPHLTFPGNRPTTTLLVDA
LTPRTLGALIALYEHKVLVQATVWDINPFDQWGVELGKILGKVVEGDLSAESVDPAKHDSSTTALIERARAALKR

Specific function: Involved in glycolysis and in gluconeogenesis. [C]

COG id: COG0166

COG function: function code G; Glucose-6-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPI family [H]

Homologues:

Organism=Homo sapiens, GI18201905, Length=541, Percent_Identity=48.9833641404806, Blast_Score=516, Evalue=1e-146,
Organism=Homo sapiens, GI296080693, Length=557, Percent_Identity=44.7037701974865, Blast_Score=459, Evalue=1e-129,
Organism=Escherichia coli, GI1790457, Length=542, Percent_Identity=49.2619926199262, Blast_Score=522, Evalue=1e-149,
Organism=Caenorhabditis elegans, GI71996708, Length=556, Percent_Identity=48.3812949640288, Blast_Score=510, Evalue=1e-145,
Organism=Caenorhabditis elegans, GI71996703, Length=552, Percent_Identity=48.3695652173913, Blast_Score=506, Evalue=1e-144,
Organism=Saccharomyces cerevisiae, GI6319673, Length=544, Percent_Identity=47.7941176470588, Blast_Score=510, Evalue=1e-145,
Organism=Drosophila melanogaster, GI24651916, Length=553, Percent_Identity=48.6437613019892, Blast_Score=516, Evalue=1e-146,
Organism=Drosophila melanogaster, GI24651914, Length=553, Percent_Identity=48.6437613019892, Blast_Score=516, Evalue=1e-146,
Organism=Drosophila melanogaster, GI17737445, Length=553, Percent_Identity=48.6437613019892, Blast_Score=516, Evalue=1e-146,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001672
- InterPro:   IPR023096
- InterPro:   IPR018189 [H]

Pfam domain/function: PF00342 PGI [H]

EC number: =5.3.1.9 [H]

Molecular weight: Translated: 61089; Mature: 60958

Theoretical pI: Translated: 6.77; Mature: 6.77

Prosite motif: PS00765 P_GLUCOSE_ISOMERASE_1 ; PS00174 P_GLUCOSE_ISOMERASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRRGIPPDSRFTRTAMTLKSLPAWTALQSHFEQIRHARLRDWFAPENDRAPTRAERFTI
CCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEC
PGGGLAADFSKNRIDDETLRLLVQLARDAGVEARRDAMFAGEIVNPTEGRAALHTALRAT
CCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHCC
DPQAPFHAQVSAERAKMATFARAVRSGTWTGYTGKRIRHVINIGIGGSDLGPKMVVHALH
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHEECCCCCCCCHHHHHHHHH
HVATPEISTHFVSNVDGADLARVLEQVDPEETLAIIVSKTFTTLETMTNARSLRDWFVAR
HHCCCCHHHHHHCCCCHHHHHHHHHHCCCHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHC
GCPEDALAKHFVGVSANPAEVVKFGIAADNVFEMWDWVGGRYSLWSAVGLSIMIAIGPEQ
CCCHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHCCEEEEEECHHH
FDELLAGANDMDRHFREAPLERNLPVLLGLIGIWYRNFFGSQSYLVAPYSEALHYLPSYL
HHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHH
QQLEMESNGKSARLDGTFVDYPTSAVTWGEPGTNGQHAFFQMLHQGPTIVPIDFIAVLTP
HHHHHCCCCCCEEECCEEEECCCCEEECCCCCCCCHHHHHHHHHCCCCEEEEEEEEEECC
EHPLAGHHPKLLANCFAQSEALMLGRTLEEARKVAGPGKEALAPHLTFPGNRPTTTLLVD
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCEEEEE
ALTPRTLGALIALYEHKVLVQATVWDINPFDQWGVELGKILGKVVEGDLSAESVDPAKHD
CCCHHHHHHHHHHHHCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
SSTTALIERARAALKR
CHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SRRGIPPDSRFTRTAMTLKSLPAWTALQSHFEQIRHARLRDWFAPENDRAPTRAERFTI
CCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEC
PGGGLAADFSKNRIDDETLRLLVQLARDAGVEARRDAMFAGEIVNPTEGRAALHTALRAT
CCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHCC
DPQAPFHAQVSAERAKMATFARAVRSGTWTGYTGKRIRHVINIGIGGSDLGPKMVVHALH
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHEECCCCCCCCHHHHHHHHH
HVATPEISTHFVSNVDGADLARVLEQVDPEETLAIIVSKTFTTLETMTNARSLRDWFVAR
HHCCCCHHHHHHCCCCHHHHHHHHHHCCCHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHC
GCPEDALAKHFVGVSANPAEVVKFGIAADNVFEMWDWVGGRYSLWSAVGLSIMIAIGPEQ
CCCHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHCCEEEEEECHHH
FDELLAGANDMDRHFREAPLERNLPVLLGLIGIWYRNFFGSQSYLVAPYSEALHYLPSYL
HHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHH
QQLEMESNGKSARLDGTFVDYPTSAVTWGEPGTNGQHAFFQMLHQGPTIVPIDFIAVLTP
HHHHHCCCCCCEEECCEEEECCCCEEECCCCCCCCHHHHHHHHHCCCCEEEEEEEEEECC
EHPLAGHHPKLLANCFAQSEALMLGRTLEEARKVAGPGKEALAPHLTFPGNRPTTTLLVD
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCEEEEE
ALTPRTLGALIALYEHKVLVQATVWDINPFDQWGVELGKILGKVVEGDLSAESVDPAKHD
CCCHHHHHHHHHHHHCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
SSTTALIERARAALKR
CHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA