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The map label for this gene is cobH [H]

Identifier: 116689695

GI number: 116689695

Start: 1859926

End: 1860552

Strand: Reverse

Name: cobH [H]

Synonym: Bcen2424_1673

Alternate gene names: 116689695

Gene position: 1860552-1859926 (Counterclockwise)

Preceding gene: 116689696

Following gene: 116689694

Centisome position: 53.4

GC content: 72.09

Gene sequence:

>627_bases
ATGCTTGACTACATTCGCGACGGGCAGGAAATCTACCGCCAGTCGTTCGCGACGATCCGCGCCGAGGCCGACCTGTCGCA
GGTTCCGCCCGATCTCGAGAAACTCGCGGTGCGCGTGATCCACGCGTGCGGGATGGTCGACGTCGTGTACGACCTGCGCT
TCTCGGCCGGCGCCGGCACGGCCGGCCGCACGGCGCTCGCGGCCGGCGCGCCGATCCTGTGCGATGCGAGGATGGTCGCC
GAAGGCATCACGCGCGCGCGGCTGCCGGCGGCCAACCGCGTGATCTGCACGCTCGGCGAGCCGGAGGTGCCCGATCTCGC
GCGCGACCTCGGCAACACGCGTTCGGCCGCCGCGCTCGAACTGTGGCGCCCGCATCTCGCGGGCAGCGTCGTCGTGATCG
GCAATGCGCCGACCGCGCTGTTCCACCTGCTCGACATGATCGACGCCGGCGCGCCGCGGCCCGCGCTGATCCTCGGTTTC
CCGGTCGGCTTCATCGGCGCGGCCGAATCGAAGGCGATGCTCGACGCCGACAGCCGCGGCGTGCCGTACGTCGCGCTGCT
CGGCCGGCGCGGCGGCAGTGCGATGGCCGCCGCCGCGGTCAATGCGCTTGCGACGGAGGTCGAATGA

Upstream 100 bases:

>100_bases
GACGCGGCCGCGGGCCTCGGCGCCCCGCTCGCGCGCCATCTGACGATTGACCAGGCCGCGGTCCGACTCATGGACGCGCG
GCACAGCCAGGACACCACCG

Downstream 100 bases:

>100_bases
CGACCGCACGCGGACGGCTGTTCGGGGTCGGCGTCGGCCCCGGCGATCCCGAGCTGATGACGATCAAGGCGCTGCGCGTG
CTGCAGGCGGCGCCGGTGGT

Product: precorrin-8X methylmutase

Products: NA

Alternate protein names: HBA synthase; Precorrin isomerase [H]

Number of amino acids: Translated: 208; Mature: 208

Protein sequence:

>208_residues
MLDYIRDGQEIYRQSFATIRAEADLSQVPPDLEKLAVRVIHACGMVDVVYDLRFSAGAGTAGRTALAAGAPILCDARMVA
EGITRARLPAANRVICTLGEPEVPDLARDLGNTRSAAALELWRPHLAGSVVVIGNAPTALFHLLDMIDAGAPRPALILGF
PVGFIGAAESKAMLDADSRGVPYVALLGRRGGSAMAAAAVNALATEVE

Sequences:

>Translated_208_residues
MLDYIRDGQEIYRQSFATIRAEADLSQVPPDLEKLAVRVIHACGMVDVVYDLRFSAGAGTAGRTALAAGAPILCDARMVA
EGITRARLPAANRVICTLGEPEVPDLARDLGNTRSAAALELWRPHLAGSVVVIGNAPTALFHLLDMIDAGAPRPALILGF
PVGFIGAAESKAMLDADSRGVPYVALLGRRGGSAMAAAAVNALATEVE
>Mature_208_residues
MLDYIRDGQEIYRQSFATIRAEADLSQVPPDLEKLAVRVIHACGMVDVVYDLRFSAGAGTAGRTALAAGAPILCDARMVA
EGITRARLPAANRVICTLGEPEVPDLARDLGNTRSAAALELWRPHLAGSVVVIGNAPTALFHLLDMIDAGAPRPALILGF
PVGFIGAAESKAMLDADSRGVPYVALLGRRGGSAMAAAAVNALATEVE

Specific function: Catalyzes the conversion of precorrin-8X to hydrogenobyrinic acid; a methyl migration reaction during the transformation of precorrin-3 to form cobyrinic acid [H]

COG id: COG2082

COG function: function code H; Precorrin isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003722 [H]

Pfam domain/function: PF02570 CbiC [H]

EC number: =5.4.1.2 [H]

Molecular weight: Translated: 21700; Mature: 21700

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDYIRDGQEIYRQSFATIRAEADLSQVPPDLEKLAVRVIHACGMVDVVYDLRFSAGAGT
CCCCHHCHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHCHHHHHHHHHCCCCCCC
AGRTALAAGAPILCDARMVAEGITRARLPAANRVICTLGEPEVPDLARDLGNTRSAAALE
CCCHHHHCCCCCEEHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHCCCCCHHHHH
LWRPHLAGSVVVIGNAPTALFHLLDMIDAGAPRPALILGFPVGFIGAAESKAMLDADSRG
HHHHHHCCCEEEECCCHHHHHHHHHHHHCCCCCCEEEEECCHHHHCCCCCCCEECCCCCC
VPYVALLGRRGGSAMAAAAVNALATEVE
CCEEEEEECCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLDYIRDGQEIYRQSFATIRAEADLSQVPPDLEKLAVRVIHACGMVDVVYDLRFSAGAGT
CCCCHHCHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHCHHHHHHHHHCCCCCCC
AGRTALAAGAPILCDARMVAEGITRARLPAANRVICTLGEPEVPDLARDLGNTRSAAALE
CCCHHHHCCCCCEEHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHCCCCCHHHHH
LWRPHLAGSVVVIGNAPTALFHLLDMIDAGAPRPALILGFPVGFIGAAESKAMLDADSRG
HHHHHHCCCEEEECCCHHHHHHHHHHHHCCCCCCEEEEECCHHHHCCCCCCCEECCCCCC
VPYVALLGRRGGSAMAAAAVNALATEVE
CCEEEEEECCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]