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The map label for this gene is rbsK [H]

Identifier: 116689632

GI number: 116689632

Start: 1771300

End: 1772235

Strand: Direct

Name: rbsK [H]

Synonym: Bcen2424_1610

Alternate gene names: 116689632

Gene position: 1771300-1772235 (Clockwise)

Preceding gene: 116689631

Following gene: 116689633

Centisome position: 50.84

GC content: 75.85

Gene sequence:

>936_bases
ATGACGGCGACCGTAACGGGCGCCGGCCGCGTGACGGTGGTCGGCAGCCTCAACATGGATCTCGTCGTGCGGGCGCCGCG
GCTGCCGCTGCCGGGCGAAACGCTCGCCGGGCACGCCTTCGCGCAGGCGGCGGGCGGCAAGGGCGGCAACCAGGCCGTCG
CCGCCGCCCGGCTCGGCGCGCAGGTCGCGATGATCGGCTGCGTCGGCGCGGATGCGCACGGCGCGGCACTGCGCGCGGGC
CTCGAGGCCGAGGGCATCGACTGCGCGGGGCTCGCGACGAGCGCGTCGGCGTCGACCGGCGTCGCGCTGATCGTCGTCGA
CGATGGGAGCCAGAACGCGATCGTGATCGTCGCGGGTGGCAACGGCGAGGTCACGACCGACACGATCGCGCGGCACGAGG
CCGCGCTGGCGGCGGCCGACGTGCTGATCTGCCAGCTCGAGACGCCGCCGGACACGGTGTTCGCGGCACTGTCGGCCGGA
CGCCGGCTCGGCCGCACGGTGGTGCTCAATCCGGCCCCGGCCGTCGCGCCGCTGCCGGACGGCTGGCTGCCGCTCGTCGA
TTACCTGATCCCGAACGAGGTCGAGGCGGCCGCGCTGACGGGGCTGCGCGTGCGCGATCCGGCCGAAGCCGAAGCCGCCG
CGCGGGCGCTCCAGGCCGGCGGCGCGCGCAACGTGCTGGTGACGCTCGGCGCACGCGGCGTGCTCGCGTTGACGGCCGAC
GGCACCGCGCGGCACTATCCGGCGCCGGTCGTGCAGGCGGTCGACACGACGGCCGCCGGCGACACCTTCATCGGCGGCTT
TTCCGCACGGCTCGCGGCCGGCGCGGACGTCGACACGGCCATCCGCTTCGCGCAATGTGCGGCGGCGCTGTCGGTCACGC
GCGCGGGCGCTCAGCCGTCGATTCCGACGCGCTCCGAACTGGCCGATCAGGCCTGA

Upstream 100 bases:

>100_bases
CGAGCGCCGTGCCGAGCCGCCGTCGCGTCGTGTCGCCGCGCCTCGTGCTGCGCGAATCGACGGCCATCTACCGTGAGCCG
GCCGCGCCGGGCGCTCGCGC

Downstream 100 bases:

>100_bases
CCCCAGGATCGCGGTTCCGTCTCGTGGCCGGTTCGTCGCACGAGACGGCCGGCCGCACCTCGCCGACCGCACCTGCCTGA
ACCTGCCGGTGCCTCGCCGG

Product: ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MTATVTGAGRVTVVGSLNMDLVVRAPRLPLPGETLAGHAFAQAAGGKGGNQAVAAARLGAQVAMIGCVGADAHGAALRAG
LEAEGIDCAGLATSASASTGVALIVVDDGSQNAIVIVAGGNGEVTTDTIARHEAALAAADVLICQLETPPDTVFAALSAG
RRLGRTVVLNPAPAVAPLPDGWLPLVDYLIPNEVEAAALTGLRVRDPAEAEAAARALQAGGARNVLVTLGARGVLALTAD
GTARHYPAPVVQAVDTTAAGDTFIGGFSARLAAGADVDTAIRFAQCAAALSVTRAGAQPSIPTRSELADQA

Sequences:

>Translated_311_residues
MTATVTGAGRVTVVGSLNMDLVVRAPRLPLPGETLAGHAFAQAAGGKGGNQAVAAARLGAQVAMIGCVGADAHGAALRAG
LEAEGIDCAGLATSASASTGVALIVVDDGSQNAIVIVAGGNGEVTTDTIARHEAALAAADVLICQLETPPDTVFAALSAG
RRLGRTVVLNPAPAVAPLPDGWLPLVDYLIPNEVEAAALTGLRVRDPAEAEAAARALQAGGARNVLVTLGARGVLALTAD
GTARHYPAPVVQAVDTTAAGDTFIGGFSARLAAGADVDTAIRFAQCAAALSVTRAGAQPSIPTRSELADQA
>Mature_310_residues
TATVTGAGRVTVVGSLNMDLVVRAPRLPLPGETLAGHAFAQAAGGKGGNQAVAAARLGAQVAMIGCVGADAHGAALRAGL
EAEGIDCAGLATSASASTGVALIVVDDGSQNAIVIVAGGNGEVTTDTIARHEAALAAADVLICQLETPPDTVFAALSAGR
RLGRTVVLNPAPAVAPLPDGWLPLVDYLIPNEVEAAALTGLRVRDPAEAEAAARALQAGGARNVLVTLGARGVLALTADG
TARHYPAPVVQAVDTTAAGDTFIGGFSARLAAGADVDTAIRFAQCAAALSVTRAGAQPSIPTRSELADQA

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=296, Percent_Identity=40.2027027027027, Blast_Score=191, Evalue=9e-49,
Organism=Escherichia coli, GI1790193, Length=303, Percent_Identity=44.5544554455446, Blast_Score=209, Evalue=1e-55,
Organism=Escherichia coli, GI87082343, Length=303, Percent_Identity=32.3432343234323, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI87081971, Length=303, Percent_Identity=26.4026402640264, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1789775, Length=260, Percent_Identity=28.8461538461538, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17532905, Length=303, Percent_Identity=38.9438943894389, Blast_Score=185, Evalue=2e-47,
Organism=Saccharomyces cerevisiae, GI6319884, Length=334, Percent_Identity=32.3353293413174, Blast_Score=146, Evalue=4e-36,
Organism=Saccharomyces cerevisiae, GI6322565, Length=278, Percent_Identity=28.7769784172662, Blast_Score=74, Evalue=3e-14,
Organism=Drosophila melanogaster, GI20128807, Length=301, Percent_Identity=38.8704318936877, Blast_Score=167, Evalue=1e-41,
Organism=Drosophila melanogaster, GI24583886, Length=301, Percent_Identity=32.2259136212625, Blast_Score=142, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 30680; Mature: 30549

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTATVTGAGRVTVVGSLNMDLVVRAPRLPLPGETLAGHAFAQAAGGKGGNQAVAAARLGA
CCEEEECCCEEEEEEECCCEEEEECCCCCCCCCHHCCHHHHHHCCCCCCCHHHHHHHHCC
QVAMIGCVGADAHGAALRAGLEAEGIDCAGLATSASASTGVALIVVDDGSQNAIVIVAGG
EEEEEEEECCCCCCHHHHCCCCCCCCCEECCCCCCCCCCCEEEEEEECCCCCEEEEEECC
NGEVTTDTIARHEAALAAADVLICQLETPPDTVFAALSAGRRLGRTVVLNPAPAVAPLPD
CCCEEHHHHHHHHHHHHEEEEEEEEECCCHHHHHHHHHHHHHHCCEEEECCCCCCCCCCC
GWLPLVDYLIPNEVEAAALTGLRVRDPAEAEAAARALQAGGARNVLVTLGARGVLALTAD
CHHHHHHHHCCCCCCHHHHCCCEECCCHHHHHHHHHHHCCCCCEEEEEECCCEEEEEEEC
GTARHYPAPVVQAVDTTAAGDTFIGGFSARLAAGADVDTAIRFAQCAAALSVTRAGAQPS
CCCCCCCCHHHHHHCCCCCCCCEECCCHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
IPTRSELADQA
CCCHHHHCCCC
>Mature Secondary Structure 
TATVTGAGRVTVVGSLNMDLVVRAPRLPLPGETLAGHAFAQAAGGKGGNQAVAAARLGA
CEEEECCCEEEEEEECCCEEEEECCCCCCCCCHHCCHHHHHHCCCCCCCHHHHHHHHCC
QVAMIGCVGADAHGAALRAGLEAEGIDCAGLATSASASTGVALIVVDDGSQNAIVIVAGG
EEEEEEEECCCCCCHHHHCCCCCCCCCEECCCCCCCCCCCEEEEEEECCCCCEEEEEECC
NGEVTTDTIARHEAALAAADVLICQLETPPDTVFAALSAGRRLGRTVVLNPAPAVAPLPD
CCCEEHHHHHHHHHHHHEEEEEEEEECCCHHHHHHHHHHHHHHCCEEEECCCCCCCCCCC
GWLPLVDYLIPNEVEAAALTGLRVRDPAEAEAAARALQAGGARNVLVTLGARGVLALTAD
CHHHHHHHHCCCCCCHHHHCCCEECCCHHHHHHHHHHHCCCCCEEEEEECCCEEEEEEEC
GTARHYPAPVVQAVDTTAAGDTFIGGFSARLAAGADVDTAIRFAQCAAALSVTRAGAQPS
CCCCCCCCHHHHHHCCCCCCCCEECCCHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
IPTRSELADQA
CCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]