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The map label for this gene is fabI [H]

Identifier: 116626829

GI number: 116626829

Start: 9779676

End: 9780446

Strand: Direct

Name: fabI [H]

Synonym: Acid_7802

Alternate gene names: 116626829

Gene position: 9779676-9780446 (Clockwise)

Preceding gene: 116626827

Following gene: 116626830

Centisome position: 98.13

GC content: 61.61

Gene sequence:

>771_bases
ATGTCGAAACTTCTAGAGGGCAAATTCGCCCTCATCCTGGGAATTGCCAACAAGTGGAGTCTGGCATATGCGATCGCGCA
GGCATTCTCGCGCGAAGGCGCCACGCTGGTTTTGACTTACCTTGGCGAGAAGCAGAAGGAAGCCATCGAGGACCTTTCCA
AAGACCTCAACGTGGCGGCGATCCTGCCGTGCGATGTTACCAAGGACGATGACCTCGCGGCGCTCACCGAATCGCTGCAG
GGCTTCCAGCGTCCGCTGCACGCGGTGGTGCACAGCCTGGCATTCGCCAACCGCGAAGATTTGAGCCGTCCCTTCATGGA
GACCAGCCGCTCCGGCTTCCTGCTGGCGCAGGACGTGAGTGCCTATTCGCTGGTCGCGGTGGCGCGCGCGGTGGCGCCGG
TGATGACCGAGGGTGGTTCGCTCAGCACGCTGACCTATGTCGGGTCCACGCGCGTGATCACGAACTATAACGTGATGGGC
GTGGCCAAGGCCTCGCTGGAAGCCGGGGTGCGTTACCTGGCAAGCGAGATGGGCGCTAAGGGAATCCGCGTGAATGCGAT
TTCCGCCGGACCGATCAAGACGGTGTCGGCGCGCGCCGTGAAAGATTTTTCGACCGTGCTGGAAGCGATCCAGACGCGCG
CCCCGTTGAAGCGCAATACGGACGCCTCGGAAGTCGCCGATACCGCGGTGTTCCTGGCCAGCGACCTGGGACGGGGTGTG
ACGGCAAACTGCCTGTTTGTTGATGCAGGCATGCAAGTATTGGGCTTCTAA

Upstream 100 bases:

>100_bases
ACTGGGCGGCGGACTGGCCATCGAAGGTCTTCATATCCCCAAGTGCCCCTATGATAGCCCAATGGGGCCTGGCTCAACAG
GTTACACTATAGGGACATTC

Downstream 100 bases:

>100_bases
GCGCGATAATAGAGTTTCGGACCTCTCAAATATGAAAGTCGAAGTGGTTCTCACGGAAGCCGACATTGCTCAAGAGTTCG
CGGAGGCCATTGAGGCTCGC

Product: enoyl-[acyl-carrier-protein] reductase [NADH]

Products: NA

Alternate protein names: Cold shock-induced protein 15; CSI15; NADH-dependent enoyl-ACP reductase; Vegetative protein 241; VEG241 [H]

Number of amino acids: Translated: 256; Mature: 255

Protein sequence:

>256_residues
MSKLLEGKFALILGIANKWSLAYAIAQAFSREGATLVLTYLGEKQKEAIEDLSKDLNVAAILPCDVTKDDDLAALTESLQ
GFQRPLHAVVHSLAFANREDLSRPFMETSRSGFLLAQDVSAYSLVAVARAVAPVMTEGGSLSTLTYVGSTRVITNYNVMG
VAKASLEAGVRYLASEMGAKGIRVNAISAGPIKTVSARAVKDFSTVLEAIQTRAPLKRNTDASEVADTAVFLASDLGRGV
TANCLFVDAGMQVLGF

Sequences:

>Translated_256_residues
MSKLLEGKFALILGIANKWSLAYAIAQAFSREGATLVLTYLGEKQKEAIEDLSKDLNVAAILPCDVTKDDDLAALTESLQ
GFQRPLHAVVHSLAFANREDLSRPFMETSRSGFLLAQDVSAYSLVAVARAVAPVMTEGGSLSTLTYVGSTRVITNYNVMG
VAKASLEAGVRYLASEMGAKGIRVNAISAGPIKTVSARAVKDFSTVLEAIQTRAPLKRNTDASEVADTAVFLASDLGRGV
TANCLFVDAGMQVLGF
>Mature_255_residues
SKLLEGKFALILGIANKWSLAYAIAQAFSREGATLVLTYLGEKQKEAIEDLSKDLNVAAILPCDVTKDDDLAALTESLQG
FQRPLHAVVHSLAFANREDLSRPFMETSRSGFLLAQDVSAYSLVAVARAVAPVMTEGGSLSTLTYVGSTRVITNYNVMGV
AKASLEAGVRYLASEMGAKGIRVNAISAGPIKTVSARAVKDFSTVLEAIQTRAPLKRNTDASEVADTAVFLASDLGRGVT
ANCLFVDAGMQVLGF

Specific function: Fatty acid biosynthesis pathway; second reduction step. [C]

COG id: COG0623

COG function: function code I; Enoyl-[acyl-carrier-protein] reductase (NADH)

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787545, Length=251, Percent_Identity=42.2310756972112, Blast_Score=210, Evalue=9e-56,
Organism=Escherichia coli, GI1790717, Length=255, Percent_Identity=25.8823529411765, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1787905, Length=249, Percent_Identity=25.3012048192771, Blast_Score=62, Evalue=5e-11,
Organism=Drosophila melanogaster, GI23397609, Length=255, Percent_Identity=26.6666666666667, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 240 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR014358
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.3.1.9 [H]

Molecular weight: Translated: 27138; Mature: 27007

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKLLEGKFALILGIANKWSLAYAIAQAFSREGATLVLTYLGEKQKEAIEDLSKDLNVAA
CCCCCCCCEEEEEEECCHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHCCCEEE
ILPCDVTKDDDLAALTESLQGFQRPLHAVVHSLAFANREDLSRPFMETSRSGFLLAQDVS
EEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCHHHHCCCCCEEEEECCH
AYSLVAVARAVAPVMTEGGSLSTLTYVGSTRVITNYNVMGVAKASLEAGVRYLASEMGAK
HHHHHHHHHHHHHHHCCCCCEEEEEEECCEEEEECCCEEEEHHHHHHHHHHHHHHHHCCC
GIRVNAISAGPIKTVSARAVKDFSTVLEAIQTRAPLKRNTDASEVADTAVFLASDLGRGV
CEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCC
TANCLFVDAGMQVLGF
EEEEEEEECCHHHHCC
>Mature Secondary Structure 
SKLLEGKFALILGIANKWSLAYAIAQAFSREGATLVLTYLGEKQKEAIEDLSKDLNVAA
CCCCCCCEEEEEEECCHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHCCCEEE
ILPCDVTKDDDLAALTESLQGFQRPLHAVVHSLAFANREDLSRPFMETSRSGFLLAQDVS
EEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCHHHHCCCCCEEEEECCH
AYSLVAVARAVAPVMTEGGSLSTLTYVGSTRVITNYNVMGVAKASLEAGVRYLASEMGAK
HHHHHHHHHHHHHHHCCCCCEEEEEEECCEEEEECCCEEEEHHHHHHHHHHHHHHHHCCC
GIRVNAISAGPIKTVSARAVKDFSTVLEAIQTRAPLKRNTDASEVADTAVFLASDLGRGV
CEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCC
TANCLFVDAGMQVLGF
EEEEEEEECCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377; 8755892; 9298659 [H]