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The map label for this gene is eco [H]

Identifier: 116626826

GI number: 116626826

Start: 9777900

End: 9778364

Strand: Direct

Name: eco [H]

Synonym: Acid_7799

Alternate gene names: 116626826

Gene position: 9777900-9778364 (Clockwise)

Preceding gene: 116626825

Following gene: 116626827

Centisome position: 98.12

GC content: 61.51

Gene sequence:

>465_bases
ATGAGACTCGTCCGATTCGCGGTATTTTTGATACTGGCTTCACTCCCCGCTTTTGGGGCCGATGACCTGAAGGCGTTTCC
CCCTGCCGAGAAAGGGATGACGCGGTATGTCATCCGGCTTCGGCAAGAGAAGAACGAAGCGGCGTTGAAGGTGGAACTGA
TTGTCGGCAAGACAGTAAAGACGGACCCCGGGAACCGCTATTTCTTCGCCGGCAAGCTGGAGACGGAGAGCATACCCGGG
TGGGGCTACGACCGCTATATTCTGCGCAAACTCGGCCCGATGGCGGGGACGCTGATGGCGGTGGACCCCAACGCCCCGCA
GGTGGAGCGGTTCATCAGCGGGAGCGGCGAGACGATGCCTCGCTACAACAGCCGGCTACCGGTGGTGGTGTACGTTCCGG
AAGGTGTCGAGGTCCGCTACCGGGTTTGGAGCGCCGGCGCGACCCAGACGGCCAAACCGGAATAA

Upstream 100 bases:

>100_bases
GCTTCGGTGTGCTGCTGGCCAAGAAAAACATTGACGAACTTCTCTATAACGAACAAGGCAATGAGGTCGTGCTGGTGAAG
TATATCGATCCTAAAGCAAA

Downstream 100 bases:

>100_bases
TCCAAACTCCCAAGGGTTTCGTATCTTCCTCAGGACGGCACAGGATGGCCAAGGTCTTTGTCACCGGGGCGACCGGGTTC
ATGGGGCGGCGGCTCTGCGG

Product: proteinase inhibitor I11, ecotin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MRLVRFAVFLILASLPAFGADDLKAFPPAEKGMTRYVIRLRQEKNEAALKVELIVGKTVKTDPGNRYFFAGKLETESIPG
WGYDRYILRKLGPMAGTLMAVDPNAPQVERFISGSGETMPRYNSRLPVVVYVPEGVEVRYRVWSAGATQTAKPE

Sequences:

>Translated_154_residues
MRLVRFAVFLILASLPAFGADDLKAFPPAEKGMTRYVIRLRQEKNEAALKVELIVGKTVKTDPGNRYFFAGKLETESIPG
WGYDRYILRKLGPMAGTLMAVDPNAPQVERFISGSGETMPRYNSRLPVVVYVPEGVEVRYRVWSAGATQTAKPE
>Mature_154_residues
MRLVRFAVFLILASLPAFGADDLKAFPPAEKGMTRYVIRLRQEKNEAALKVELIVGKTVKTDPGNRYFFAGKLETESIPG
WGYDRYILRKLGPMAGTLMAVDPNAPQVERFISGSGETMPRYNSRLPVVVYVPEGVEVRYRVWSAGATQTAKPE

Specific function: General inhibitor of pancreatic serine proteases:inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases [H]

COG id: COG4574

COG function: function code R; Serine protease inhibitor ecotin

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protease inhibitor I11 (ecotin) family [H]

Homologues:

Organism=Escherichia coli, GI1788538, Length=147, Percent_Identity=40.8163265306122, Blast_Score=115, Evalue=2e-27,

Paralogues:

None

Copy number: 260 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005658
- InterPro:   IPR023189
- InterPro:   IPR023084 [H]

Pfam domain/function: PF03974 Ecotin [H]

EC number: NA

Molecular weight: Translated: 17181; Mature: 17181

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLVRFAVFLILASLPAFGADDLKAFPPAEKGMTRYVIRLRQEKNEAALKVELIVGKTVK
CHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEEEEEECCEEE
TDPGNRYFFAGKLETESIPGWGYDRYILRKLGPMAGTLMAVDPNAPQVERFISGSGETMP
CCCCCEEEEEEEEECCCCCCCCHHHHHHHHCCCCCCEEEEECCCCHHHHHHHCCCCCCCC
RYNSRLPVVVYVPEGVEVRYRVWSAGATQTAKPE
CCCCCCCEEEECCCCCEEEEEEEECCCCCCCCCC
>Mature Secondary Structure
MRLVRFAVFLILASLPAFGADDLKAFPPAEKGMTRYVIRLRQEKNEAALKVELIVGKTVK
CHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEEEEEECCEEE
TDPGNRYFFAGKLETESIPGWGYDRYILRKLGPMAGTLMAVDPNAPQVERFISGSGETMP
CCCCCEEEEEEEEECCCCCCCCHHHHHHHHCCCCCCEEEEECCCCHHHHHHHCCCCCCCC
RYNSRLPVVVYVPEGVEVRYRVWSAGATQTAKPE
CCCCCCCEEEECCCCCEEEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA