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The map label for this gene is barA [H]

Identifier: 116624414

GI number: 116624414

Start: 6688339

End: 6692388

Strand: Reverse

Name: barA [H]

Synonym: Acid_5336

Alternate gene names: 116624414

Gene position: 6692388-6688339 (Counterclockwise)

Preceding gene: 116624415

Following gene: 116624413

Centisome position: 67.15

GC content: 63.95

Gene sequence:

>4050_bases
TTGTTTGACACTGTGCAGAGGTTATCGCCCCGCCAAGAAACCGGAATCCTTGTGGCCTGCCTGGCCGTCGCGGCCGGAGT
CGTCCAACTGCGGGCCGAGGATCGCTTCGCCTGGCGTTCCTGGGGGGTCCGCGAAGGCCTGACCGAAACCTATTCGTTTG
CCCTGAGCGTGACGCCCGGCCAAGGCGCATTCATCCGCCATGGCGCCGTGCCTTCTATGAGCGTATTTGACGGCATTGGC
GTGACCCGTCTGCCGGATCCGCGCGGCGGCGGCCAGCCGGACTGGCCATCCACGCGTCGCGTGTATCCTGCCCCAAGTGG
CACCCCTGCTGGCACGCCCTGGACGTCCACTCCAAAGGCCCTGCTCCAATACAAGGAGGGAAAGTGGCGTGTCCGCTACA
CCGCTCCAGCGGGACAGCAGCTGATGGCTGCGGTCCCGGCGGGTCGGCGCGTACTCGTGCTTCTCGATGACAGCCTCCGC
GAGTTCGATCCCGAATCGGGGACGTGGCGGGAACTGCGGAGCGTGCGGAATTCCAGGGTCGGCCCCTTCCGTGGGATGTG
TTCCGGTGGAGTCGGCGAATGGTACATCACTGCGGAACAGGGTCTCGCCAGACTGCGCCTGGAGCGCGACGGCGGAGCCT
TCGAGTGGACCGAAATCAACAGTCGGGCCTCCGGCCTCCGCAGCTTCAACTACCCCATCGCCGGAAGCGGCGAGGTGTTC
GCGCAGGCAACCTCCGCCCGCGATCCGCGCCGCGTGATCGTGCGCTGGTCGGGCGGCGAACTCGAGGTGGTTTACGCCGC
ACAGTCGGATAACCTGCGCGGCTGGCGCGCCGGCGATGGCAGCTTGTGGATCCTCGAGGGCGGGGACCTTTTCTTTCTGC
TCAACGGCCACCGGTATCCGGTGGAGAGAACGGGTGTCCTCAGCGGCAACATCTTCGATGTCTATTCCGAAGCGGGCAAC
GCGTTCTGGGTGGCGACATCGGAAGGCATCACGCGCCATACGCCGTCGTTATGGCAGGCGCCCGCCGGACTCGCCGGTTT
CGACCTTCCGGTTCATTCGATCGCGGAAGACCGGCAAGGCCGGATCTGGATGAGCGCTACGGAGTATCTGTTGGAACAGG
TAGGCGACGGGTGGAAATTTCACAAGCTGCCCTTCGGCTTCCGCACCCATACCGTTCAAACCGAAAGTCTTGCGCCGCTG
CCCGATGGCAGAGTATTGGTCAAAGTAGTTCGGGCCGACCGCTCCGACGCGGTCCTGGCGCTGGACCCGGTTAGCGGCCG
TTTCTCCGAACTTGCCCAACCTGAAGGGCGCCGGATCACTCTTCTGGAGCGGCGCCCCGCCGGCGGCGTATGGGCTGGCA
GCGAAGTCGATGGCAAGCCCGGCTTCCGCCTCGAATTCTATGATGGCCGTGACTTTCGAAAAGTCCTCGAACTGGGCAGC
GAGTGGCACGGAGCCAACCTGCGCTGTGTGCTCGAACGTGACGGAGAGATCTGGCTGGGCGGCTCGGCGGGCGGCGGCCT
CTACCGCGGTGGCCGGTTCTCAGAGCCTCTGCAAGCCGCGAATGGCTATCCCGGGACCGCCGTCTTCGTGCTCGGCCTGA
CGCCTGGCGGCGAACTTGTTGCCGGCGGACGCGACCAAATCTTCAAATTCGACGACAGATCCTGGACGGTAGTGCGTCAA
GATCTGGACCGCATTCGCCAGTTCAGCCACACGCGCGATGGCGCCCTCTGGGTGGCCTCCGCCTCCGGCGTTCACCGCTA
CAAGGATGGAAGCTGGATCACTCATCAGGCCGAAGAAGGACTTCCCTCGGTCATTGCCTATACCGTGTTCGAGGACAGCC
GGGGACGCCTATGGGCCGGGACTACGCGCGGAGTGGCAATGTATCATCCCGAGGCCGATCCCGATCCTCCGCGAACCACT
CTGGATCCCGGGGCCAATCTTACCGAAGCCTCGTTATCCGGAGAGGCGCGAATCACCTTTGGCGGGATCGATAAGTGGAG
CCTGACTCCTGCCGATCGCCTGCTGTTCTCCTATCGCCTGGATGGAGGGCCATGGTCGCCTTTCGAGGACGTCGATCTAG
CAACCTATCACGGCCTGCGCGCCGGGACGCACCATTTCGATGTGCGCTCCATGGATCGCAACGGCAACATCGATCGCGCC
GGCCAGTCGTTTGCCTTTGCGGTGCCATGGCCCTGGTTTCGCCAACTCGGATTTCTCGCCTTGCTGAGCGTGGGCTCGTG
CGCAATCATCGTGCTCGCCTGCGTCGCCGCGATCCAGTACCGCCGCCGCGGCAGCCTGATCCTGGAATTGAACCGCGCCA
AGGAACAGGCCGAGGCCGCCAGCCGGCACAAGACCGAATTCCTCGCGAATATGAGCCACGAGATTCGTACGCCGATGAAT
GGCGTCATCGGGATGACCGGCCTTCTCCTCGATACCGAACTGACCACCGAGCAGCGCGATTATGCCGGCACGGTGCGCCG
TTCGGGCGAGTCGCTGTTGACCCTCATCAACGACATCCTCGATTTCTCCAAGGTCGAAGCCGGCAAACTGGCGATCGAGG
CCAGTGCGTTCGACCTGCGCTCTACGATCGAAGAGGTGGACGAAATGCTGGCACCTAAAATTGAAAACCGCAAACTCGAC
CTGGTGCTCCAGTACCCGGTCGGTGCACCCCGCCATTTCGTTGGCGACGCCGGCCGCATTCGTCAGGTAGTGACCAACCT
GGTGGGCAATGCGATCAAGTTCACCGGCGAAGGCAGCATCGTGATCGAGGTCGTTTGCGAGTCGCAGGATGAGGCACGGG
CCGTCATGCGCGTGGCCATTCACGACACCGGCCCCGGCATTCCCTCGGAGAAGATCGGCTCGTTATTCGAGAAATTCAGC
CAGTTGGATGGGTCCACGACCAGAAAGTACGGCGGTACCGGCCTCGGGCTCGCGATCTCGAAGCAATTGGTGAGCCTGAT
GGGCGGTTCCATGGCGGTAAGCAGCCGGCTCGGCGAGGGTTCCACCTTCTCTTTCACCCTGCCCCTGCCGCTGGACGCCA
ACTCACCCGTCGAGCCCCTCACGGCCGCCGGCCTGCGCGGCCTTCGCGCCCTGATTGTGGACGATAACGAAATCAATCGG
CGCGTGCTGCACGAACAGATCATCGGTTGGGGCATGCGCAATGGGAGTTTCGCCGCCGGCGAAGAGGCCTTGGTCGCGCT
GCGCGCCGCGCATGCCGCCGGCGATCCATACCACTTCGCGATCCTGGATTACCGCATGCCCGGTATGGACGGCGTCGAAG
TTGCGCGCGCCATTAAGGCGGACGATGAACTCCGTGAAACCGTGGTCGTGCTCCTGACCTCAGTCGGTCAGTGGAGCGAG
GCCAGGCAGAAAGAGAGCGGCATCGTCGATGCTTCCCTGGTCAAGCCGGTACGGCAATCGCAGTTGTTGAATATTCTCTC
CTCCTGCTGGGTGAGAACAAACAGCATCACGGCCGCGCCTGCAGTCCGGCCCGAGCCTCCGGTGAACGAAATGCGCGCTG
CTCTTGCCTTGCGTTTCGGTGGTGTGCCGGTCCGCGTGCTGGTGGCCGAAGATAACGTCGTCAACCAAAAGGTCTCCGCG
CGCATGCTGGACAAACTGGGTATTCGCGCCGATGTGGCGGCCGATGGGCGCGAGGCCGTGGCCCTGTTCGGACTGGTGCC
CTACGACTTGATCTTCATGGATTGCCAGATGCCCGAGATGGATGGCTACGCCGCCACCCGGGAGATTCGCCGCCGCGAAG
GCCCTGGCCGGCGGGTACCGATTGCCGCCATGACCGCGGAGGTGCTGGGCGGCTGCCGCGAACTCTGCCTGGCGGCCGGC
ATGGACGACCACATCCCCAAGCCGGTCAAGATGGAGGTCCTCTTCGAGACCCTTCGCCGCTGGATTCCCGCGCGCAACTG
CCCCGAACCCGGCGATTCCGCCATGCTAACCTCTGGCTGTGCTGCTTCCCGTGATGGTGGCAATGTTTCTCCAGACCGAC
CCGCAGGCGCTGCTCCCCTTGTACGAGCAGGCCCTCCAGCGGCGCCGTAA

Upstream 100 bases:

>100_bases
CGGCCGGGTGTACGTGGACGCCAAGTCCCGCGTCGATGTCTACGGCTTGTTGTCCAACCGCTGAATATTCCTAATCAAAA
TCCCAGGAATTGCCGATGAG

Downstream 100 bases:

>100_bases
GGAATTCGGCGCGGCCGATCCGCGGACCGCCCAGGCCGCGCGAGATCTCGGGCTCTTCCTCGCCGGAATCGGCGATCCCG
CGGCCGCGCGCCCGGCGCTG

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 1349; Mature: 1349

Protein sequence:

>1349_residues
MFDTVQRLSPRQETGILVACLAVAAGVVQLRAEDRFAWRSWGVREGLTETYSFALSVTPGQGAFIRHGAVPSMSVFDGIG
VTRLPDPRGGGQPDWPSTRRVYPAPSGTPAGTPWTSTPKALLQYKEGKWRVRYTAPAGQQLMAAVPAGRRVLVLLDDSLR
EFDPESGTWRELRSVRNSRVGPFRGMCSGGVGEWYITAEQGLARLRLERDGGAFEWTEINSRASGLRSFNYPIAGSGEVF
AQATSARDPRRVIVRWSGGELEVVYAAQSDNLRGWRAGDGSLWILEGGDLFFLLNGHRYPVERTGVLSGNIFDVYSEAGN
AFWVATSEGITRHTPSLWQAPAGLAGFDLPVHSIAEDRQGRIWMSATEYLLEQVGDGWKFHKLPFGFRTHTVQTESLAPL
PDGRVLVKVVRADRSDAVLALDPVSGRFSELAQPEGRRITLLERRPAGGVWAGSEVDGKPGFRLEFYDGRDFRKVLELGS
EWHGANLRCVLERDGEIWLGGSAGGGLYRGGRFSEPLQAANGYPGTAVFVLGLTPGGELVAGGRDQIFKFDDRSWTVVRQ
DLDRIRQFSHTRDGALWVASASGVHRYKDGSWITHQAEEGLPSVIAYTVFEDSRGRLWAGTTRGVAMYHPEADPDPPRTT
LDPGANLTEASLSGEARITFGGIDKWSLTPADRLLFSYRLDGGPWSPFEDVDLATYHGLRAGTHHFDVRSMDRNGNIDRA
GQSFAFAVPWPWFRQLGFLALLSVGSCAIIVLACVAAIQYRRRGSLILELNRAKEQAEAASRHKTEFLANMSHEIRTPMN
GVIGMTGLLLDTELTTEQRDYAGTVRRSGESLLTLINDILDFSKVEAGKLAIEASAFDLRSTIEEVDEMLAPKIENRKLD
LVLQYPVGAPRHFVGDAGRIRQVVTNLVGNAIKFTGEGSIVIEVVCESQDEARAVMRVAIHDTGPGIPSEKIGSLFEKFS
QLDGSTTRKYGGTGLGLAISKQLVSLMGGSMAVSSRLGEGSTFSFTLPLPLDANSPVEPLTAAGLRGLRALIVDDNEINR
RVLHEQIIGWGMRNGSFAAGEEALVALRAAHAAGDPYHFAILDYRMPGMDGVEVARAIKADDELRETVVVLLTSVGQWSE
ARQKESGIVDASLVKPVRQSQLLNILSSCWVRTNSITAAPAVRPEPPVNEMRAALALRFGGVPVRVLVAEDNVVNQKVSA
RMLDKLGIRADVAADGREAVALFGLVPYDLIFMDCQMPEMDGYAATREIRRREGPGRRVPIAAMTAEVLGGCRELCLAAG
MDDHIPKPVKMEVLFETLRRWIPARNCPEPGDSAMLTSGCAASRDGGNVSPDRPAGAAPLVRAGPPAAP

Sequences:

>Translated_1349_residues
MFDTVQRLSPRQETGILVACLAVAAGVVQLRAEDRFAWRSWGVREGLTETYSFALSVTPGQGAFIRHGAVPSMSVFDGIG
VTRLPDPRGGGQPDWPSTRRVYPAPSGTPAGTPWTSTPKALLQYKEGKWRVRYTAPAGQQLMAAVPAGRRVLVLLDDSLR
EFDPESGTWRELRSVRNSRVGPFRGMCSGGVGEWYITAEQGLARLRLERDGGAFEWTEINSRASGLRSFNYPIAGSGEVF
AQATSARDPRRVIVRWSGGELEVVYAAQSDNLRGWRAGDGSLWILEGGDLFFLLNGHRYPVERTGVLSGNIFDVYSEAGN
AFWVATSEGITRHTPSLWQAPAGLAGFDLPVHSIAEDRQGRIWMSATEYLLEQVGDGWKFHKLPFGFRTHTVQTESLAPL
PDGRVLVKVVRADRSDAVLALDPVSGRFSELAQPEGRRITLLERRPAGGVWAGSEVDGKPGFRLEFYDGRDFRKVLELGS
EWHGANLRCVLERDGEIWLGGSAGGGLYRGGRFSEPLQAANGYPGTAVFVLGLTPGGELVAGGRDQIFKFDDRSWTVVRQ
DLDRIRQFSHTRDGALWVASASGVHRYKDGSWITHQAEEGLPSVIAYTVFEDSRGRLWAGTTRGVAMYHPEADPDPPRTT
LDPGANLTEASLSGEARITFGGIDKWSLTPADRLLFSYRLDGGPWSPFEDVDLATYHGLRAGTHHFDVRSMDRNGNIDRA
GQSFAFAVPWPWFRQLGFLALLSVGSCAIIVLACVAAIQYRRRGSLILELNRAKEQAEAASRHKTEFLANMSHEIRTPMN
GVIGMTGLLLDTELTTEQRDYAGTVRRSGESLLTLINDILDFSKVEAGKLAIEASAFDLRSTIEEVDEMLAPKIENRKLD
LVLQYPVGAPRHFVGDAGRIRQVVTNLVGNAIKFTGEGSIVIEVVCESQDEARAVMRVAIHDTGPGIPSEKIGSLFEKFS
QLDGSTTRKYGGTGLGLAISKQLVSLMGGSMAVSSRLGEGSTFSFTLPLPLDANSPVEPLTAAGLRGLRALIVDDNEINR
RVLHEQIIGWGMRNGSFAAGEEALVALRAAHAAGDPYHFAILDYRMPGMDGVEVARAIKADDELRETVVVLLTSVGQWSE
ARQKESGIVDASLVKPVRQSQLLNILSSCWVRTNSITAAPAVRPEPPVNEMRAALALRFGGVPVRVLVAEDNVVNQKVSA
RMLDKLGIRADVAADGREAVALFGLVPYDLIFMDCQMPEMDGYAATREIRRREGPGRRVPIAAMTAEVLGGCRELCLAAG
MDDHIPKPVKMEVLFETLRRWIPARNCPEPGDSAMLTSGCAASRDGGNVSPDRPAGAAPLVRAGPPAAP
>Mature_1349_residues
MFDTVQRLSPRQETGILVACLAVAAGVVQLRAEDRFAWRSWGVREGLTETYSFALSVTPGQGAFIRHGAVPSMSVFDGIG
VTRLPDPRGGGQPDWPSTRRVYPAPSGTPAGTPWTSTPKALLQYKEGKWRVRYTAPAGQQLMAAVPAGRRVLVLLDDSLR
EFDPESGTWRELRSVRNSRVGPFRGMCSGGVGEWYITAEQGLARLRLERDGGAFEWTEINSRASGLRSFNYPIAGSGEVF
AQATSARDPRRVIVRWSGGELEVVYAAQSDNLRGWRAGDGSLWILEGGDLFFLLNGHRYPVERTGVLSGNIFDVYSEAGN
AFWVATSEGITRHTPSLWQAPAGLAGFDLPVHSIAEDRQGRIWMSATEYLLEQVGDGWKFHKLPFGFRTHTVQTESLAPL
PDGRVLVKVVRADRSDAVLALDPVSGRFSELAQPEGRRITLLERRPAGGVWAGSEVDGKPGFRLEFYDGRDFRKVLELGS
EWHGANLRCVLERDGEIWLGGSAGGGLYRGGRFSEPLQAANGYPGTAVFVLGLTPGGELVAGGRDQIFKFDDRSWTVVRQ
DLDRIRQFSHTRDGALWVASASGVHRYKDGSWITHQAEEGLPSVIAYTVFEDSRGRLWAGTTRGVAMYHPEADPDPPRTT
LDPGANLTEASLSGEARITFGGIDKWSLTPADRLLFSYRLDGGPWSPFEDVDLATYHGLRAGTHHFDVRSMDRNGNIDRA
GQSFAFAVPWPWFRQLGFLALLSVGSCAIIVLACVAAIQYRRRGSLILELNRAKEQAEAASRHKTEFLANMSHEIRTPMN
GVIGMTGLLLDTELTTEQRDYAGTVRRSGESLLTLINDILDFSKVEAGKLAIEASAFDLRSTIEEVDEMLAPKIENRKLD
LVLQYPVGAPRHFVGDAGRIRQVVTNLVGNAIKFTGEGSIVIEVVCESQDEARAVMRVAIHDTGPGIPSEKIGSLFEKFS
QLDGSTTRKYGGTGLGLAISKQLVSLMGGSMAVSSRLGEGSTFSFTLPLPLDANSPVEPLTAAGLRGLRALIVDDNEINR
RVLHEQIIGWGMRNGSFAAGEEALVALRAAHAAGDPYHFAILDYRMPGMDGVEVARAIKADDELRETVVVLLTSVGQWSE
ARQKESGIVDASLVKPVRQSQLLNILSSCWVRTNSITAAPAVRPEPPVNEMRAALALRFGGVPVRVLVAEDNVVNQKVSA
RMLDKLGIRADVAADGREAVALFGLVPYDLIFMDCQMPEMDGYAATREIRRREGPGRRVPIAAMTAEVLGGCRELCLAAG
MDDHIPKPVKMEVLFETLRRWIPARNCPEPGDSAMLTSGCAASRDGGNVSPDRPAGAAPLVRAGPPAAP

Specific function: Member of the two-component regulatory system UvrY/BarA involved in the regulation of carbon metabolism via the CsrA/CsrB regulatory system. Phosphorylates UvrY, probably via a four-step phosphorelay [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=548, Percent_Identity=36.4963503649635, Blast_Score=309, Evalue=8e-85,
Organism=Escherichia coli, GI87081816, Length=338, Percent_Identity=36.6863905325444, Blast_Score=201, Evalue=4e-52,
Organism=Escherichia coli, GI48994928, Length=338, Percent_Identity=31.9526627218935, Blast_Score=186, Evalue=1e-47,
Organism=Escherichia coli, GI1788713, Length=385, Percent_Identity=32.2077922077922, Blast_Score=163, Evalue=7e-41,
Organism=Escherichia coli, GI145693157, Length=264, Percent_Identity=36.7424242424242, Blast_Score=162, Evalue=1e-40,
Organism=Escherichia coli, GI1786600, Length=242, Percent_Identity=30.1652892561983, Blast_Score=102, Evalue=1e-22,
Organism=Escherichia coli, GI1786783, Length=246, Percent_Identity=28.4552845528455, Blast_Score=100, Evalue=6e-22,
Organism=Escherichia coli, GI1788393, Length=256, Percent_Identity=26.171875, Blast_Score=95, Evalue=3e-20,
Organism=Escherichia coli, GI1786912, Length=248, Percent_Identity=27.8225806451613, Blast_Score=94, Evalue=6e-20,
Organism=Escherichia coli, GI1790436, Length=281, Percent_Identity=25.6227758007117, Blast_Score=88, Evalue=4e-18,
Organism=Escherichia coli, GI87082128, Length=238, Percent_Identity=27.7310924369748, Blast_Score=77, Evalue=1e-14,
Organism=Escherichia coli, GI1788549, Length=238, Percent_Identity=25.2100840336134, Blast_Score=74, Evalue=6e-14,
Organism=Escherichia coli, GI1790551, Length=216, Percent_Identity=31.0185185185185, Blast_Score=74, Evalue=8e-14,
Organism=Escherichia coli, GI1788279, Length=226, Percent_Identity=23.4513274336283, Blast_Score=68, Evalue=4e-12,
Organism=Escherichia coli, GI1787894, Length=250, Percent_Identity=27.2, Blast_Score=66, Evalue=1e-11,
Organism=Escherichia coli, GI1790346, Length=199, Percent_Identity=27.6381909547739, Blast_Score=64, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=127, Percent_Identity=39.3700787401575, Blast_Score=82, Evalue=8e-16,
Organism=Saccharomyces cerevisiae, GI6322000, Length=137, Percent_Identity=31.3868613138686, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR019247
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF09984 DUF2222; PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 146834; Mature: 146834

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00037 MYB_1 ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDTVQRLSPRQETGILVACLAVAAGVVQLRAEDRFAWRSWGVREGLTETYSFALSVTPG
CCCCHHHCCCCHHCCHHHHHHHHHHHHHEEECCCCHHHHHCCHHHCCCCEEEEEEEECCC
QGAFIRHGAVPSMSVFDGIGVTRLPDPRGGGQPDWPSTRRVYPAPSGTPAGTPWTSTPKA
CCCEEECCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCHHH
LLQYKEGKWRVRYTAPAGQQLMAAVPAGRRVLVLLDDSLREFDPESGTWRELRSVRNSRV
HHHCCCCCEEEEEECCCCCHHHHCCCCCCEEEEEECCHHHHCCCCCCCHHHHHHHHHCCC
GPFRGMCSGGVGEWYITAEQGLARLRLERDGGAFEWTEINSRASGLRSFNYPIAGSGEVF
CCCCCCCCCCCCCEEEECCCCCEEEEEECCCCEEEEEECCCHHHHHHHCCCCCCCCCHHE
AQATSARDPRRVIVRWSGGELEVVYAAQSDNLRGWRAGDGSLWILEGGDLFFLLNGHRYP
EEECCCCCCEEEEEEECCCCEEEEEEECCCCCCCEECCCCCEEEEECCCEEEEECCCCCC
VERTGVLSGNIFDVYSEAGNAFWVATSEGITRHTPSLWQAPAGLAGFDLPVHSIAEDRQG
CCCCCEECCCHHHHHHCCCCEEEEEECCCCCCCCCHHHCCCCCCCCCCCCHHHHHCCCCC
RIWMSATEYLLEQVGDGWKFHKLPFGFRTHTVQTESLAPLPDGRVLVKVVRADRSDAVLA
EEEEHHHHHHHHHHCCCCEEEECCCCCEEEEEECCCCCCCCCCCEEEEEECCCCCCCEEE
LDPVSGRFSELAQPEGRRITLLERRPAGGVWAGSEVDGKPGFRLEFYDGRDFRKVLELGS
ECCCCCHHHHHCCCCCCEEEEEEECCCCCEECCCCCCCCCCEEEEEECCHHHHHHHHCCC
EWHGANLRCVLERDGEIWLGGSAGGGLYRGGRFSEPLQAANGYPGTAVFVLGLTPGGELV
CCCCCCEEEEEECCCCEEECCCCCCCCCCCCCCCCHHHHCCCCCCEEEEEEEECCCCCEE
AGGRDQIFKFDDRSWTVVRQDLDRIRQFSHTRDGALWVASASGVHRYKDGSWITHQAEEG
ECCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEECCCCEEEEHHHCC
LPSVIAYTVFEDSRGRLWAGTTRGVAMYHPEADPDPPRTTLDPGANLTEASLSGEARITF
CCCEEEEEEEECCCCCEEECCCCCEEEECCCCCCCCCCCCCCCCCCCCHHCCCCCEEEEE
GGIDKWSLTPADRLLFSYRLDGGPWSPFEDVDLATYHGLRAGTHHFDVRSMDRNGNIDRA
CCCCCCCCCHHHHEEEEEEECCCCCCCCCCCCHHHHCCCCCCCCEEEEEECCCCCCCCCC
GQSFAFAVPWPWFRQLGFLALLSVGSCAIIVLACVAAIQYRRRGSLILELNRAKEQAEAA
CCCEEEECCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHH
SRHKTEFLANMSHEIRTPMNGVIGMTGLLLDTELTTEQRDYAGTVRRSGESLLTLINDIL
HHHHHHHHHHHHHHHCCCCCHHHHHHHEEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHH
DFSKVEAGKLAIEASAFDLRSTIEEVDEMLAPKIENRKLDLVLQYPVGAPRHFVGDAGRI
HHHHCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHCCCHHHH
RQVVTNLVGNAIKFTGEGSIVIEVVCESQDEARAVMRVAIHDTGPGIPSEKIGSLFEKFS
HHHHHHHHCCCEEEECCCCEEEEEEECCCHHHHHEEEEEEECCCCCCCHHHHHHHHHHHH
QLDGSTTRKYGGTGLGLAISKQLVSLMGGSMAVSSRLGEGSTFSFTLPLPLDANSPVEPL
HCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHCCCCCEEEEEEECCCCCCCCCCHH
TAAGLRGLRALIVDDNEINRRVLHEQIIGWGMRNGSFAAGEEALVALRAAHAAGDPYHFA
HHHHHCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEE
ILDYRMPGMDGVEVARAIKADDELRETVVVLLTSVGQWSEARQKESGIVDASLVKPVRQS
EEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHH
QLLNILSSCWVRTNSITAAPAVRPEPPVNEMRAALALRFGGVPVRVLVAEDNVVNQKVSA
HHHHHHHHHHEECCCEEECCCCCCCCCHHHHHHHHHHEECCCEEEEEEECCCHHHHHHHH
RMLDKLGIRADVAADGREAVALFGLVPYDLIFMDCQMPEMDGYAATREIRRREGPGRRVP
HHHHHCCCEEEECCCCCCEEEEEECCCEEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCC
IAAMTAEVLGGCRELCLAAGMDDHIPKPVKMEVLFETLRRWIPARNCPEPGDSAMLTSGC
HHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCC
AASRDGGNVSPDRPAGAAPLVRAGPPAAP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MFDTVQRLSPRQETGILVACLAVAAGVVQLRAEDRFAWRSWGVREGLTETYSFALSVTPG
CCCCHHHCCCCHHCCHHHHHHHHHHHHHEEECCCCHHHHHCCHHHCCCCEEEEEEEECCC
QGAFIRHGAVPSMSVFDGIGVTRLPDPRGGGQPDWPSTRRVYPAPSGTPAGTPWTSTPKA
CCCEEECCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCHHH
LLQYKEGKWRVRYTAPAGQQLMAAVPAGRRVLVLLDDSLREFDPESGTWRELRSVRNSRV
HHHCCCCCEEEEEECCCCCHHHHCCCCCCEEEEEECCHHHHCCCCCCCHHHHHHHHHCCC
GPFRGMCSGGVGEWYITAEQGLARLRLERDGGAFEWTEINSRASGLRSFNYPIAGSGEVF
CCCCCCCCCCCCCEEEECCCCCEEEEEECCCCEEEEEECCCHHHHHHHCCCCCCCCCHHE
AQATSARDPRRVIVRWSGGELEVVYAAQSDNLRGWRAGDGSLWILEGGDLFFLLNGHRYP
EEECCCCCCEEEEEEECCCCEEEEEEECCCCCCCEECCCCCEEEEECCCEEEEECCCCCC
VERTGVLSGNIFDVYSEAGNAFWVATSEGITRHTPSLWQAPAGLAGFDLPVHSIAEDRQG
CCCCCEECCCHHHHHHCCCCEEEEEECCCCCCCCCHHHCCCCCCCCCCCCHHHHHCCCCC
RIWMSATEYLLEQVGDGWKFHKLPFGFRTHTVQTESLAPLPDGRVLVKVVRADRSDAVLA
EEEEHHHHHHHHHHCCCCEEEECCCCCEEEEEECCCCCCCCCCCEEEEEECCCCCCCEEE
LDPVSGRFSELAQPEGRRITLLERRPAGGVWAGSEVDGKPGFRLEFYDGRDFRKVLELGS
ECCCCCHHHHHCCCCCCEEEEEEECCCCCEECCCCCCCCCCEEEEEECCHHHHHHHHCCC
EWHGANLRCVLERDGEIWLGGSAGGGLYRGGRFSEPLQAANGYPGTAVFVLGLTPGGELV
CCCCCCEEEEEECCCCEEECCCCCCCCCCCCCCCCHHHHCCCCCCEEEEEEEECCCCCEE
AGGRDQIFKFDDRSWTVVRQDLDRIRQFSHTRDGALWVASASGVHRYKDGSWITHQAEEG
ECCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEECCCCEEEEHHHCC
LPSVIAYTVFEDSRGRLWAGTTRGVAMYHPEADPDPPRTTLDPGANLTEASLSGEARITF
CCCEEEEEEEECCCCCEEECCCCCEEEECCCCCCCCCCCCCCCCCCCCHHCCCCCEEEEE
GGIDKWSLTPADRLLFSYRLDGGPWSPFEDVDLATYHGLRAGTHHFDVRSMDRNGNIDRA
CCCCCCCCCHHHHEEEEEEECCCCCCCCCCCCHHHHCCCCCCCCEEEEEECCCCCCCCCC
GQSFAFAVPWPWFRQLGFLALLSVGSCAIIVLACVAAIQYRRRGSLILELNRAKEQAEAA
CCCEEEECCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHH
SRHKTEFLANMSHEIRTPMNGVIGMTGLLLDTELTTEQRDYAGTVRRSGESLLTLINDIL
HHHHHHHHHHHHHHHCCCCCHHHHHHHEEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHH
DFSKVEAGKLAIEASAFDLRSTIEEVDEMLAPKIENRKLDLVLQYPVGAPRHFVGDAGRI
HHHHCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHCCCHHHH
RQVVTNLVGNAIKFTGEGSIVIEVVCESQDEARAVMRVAIHDTGPGIPSEKIGSLFEKFS
HHHHHHHHCCCEEEECCCCEEEEEEECCCHHHHHEEEEEEECCCCCCCHHHHHHHHHHHH
QLDGSTTRKYGGTGLGLAISKQLVSLMGGSMAVSSRLGEGSTFSFTLPLPLDANSPVEPL
HCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHCCCCCEEEEEEECCCCCCCCCCHH
TAAGLRGLRALIVDDNEINRRVLHEQIIGWGMRNGSFAAGEEALVALRAAHAAGDPYHFA
HHHHHCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEE
ILDYRMPGMDGVEVARAIKADDELRETVVVLLTSVGQWSEARQKESGIVDASLVKPVRQS
EEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHH
QLLNILSSCWVRTNSITAAPAVRPEPPVNEMRAALALRFGGVPVRVLVAEDNVVNQKVSA
HHHHHHHHHHEECCCEEECCCCCCCCCHHHHHHHHHHEECCCEEEEEEECCCHHHHHHHH
RMLDKLGIRADVAADGREAVALFGLVPYDLIFMDCQMPEMDGYAATREIRRREGPGRRVP
HHHHHCCCEEEECCCCCCEEEEEECCCEEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCC
IAAMTAEVLGGCRELCLAAGMDDHIPKPVKMEVLFETLRRWIPARNCPEPGDSAMLTSGC
HHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCC
AASRDGGNVSPDRPAGAAPLVRAGPPAAP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]