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The map label for this gene is uxaC

Identifier: 116624408

GI number: 116624408

Start: 6680046

End: 6681449

Strand: Reverse

Name: uxaC

Synonym: Acid_5330

Alternate gene names: 116624408

Gene position: 6681449-6680046 (Counterclockwise)

Preceding gene: 116624413

Following gene: 116624407

Centisome position: 67.04

GC content: 61.47

Gene sequence:

>1404_bases
ATGTCTTTTATCCACGACGATTTTCTACTCAGCAGCAAAACTGCGCGGCGTTTCTATCACACGTTCGCCGAAGATCAGCC
GATTCTGGACTATCACTGCCATCTGCCGCCTCAGGACGTGGCCGCGAATCGCCAATTTAAGGATCTCTTCGAAATCTGGC
TGGAGGGCGACCACTATAAATGGCGCGCCATGCGTGCCAACGGAGTGCCGGAGTCGCACTGCACGGGCAACGCTCCGGCT
TACGAGAAATTCATGGCCTGGGCGAAGACCGTGCCGGCCACCCTGCGCAACCCCCTGTACCACTGGACCCACCTGGAGCT
GAAGCGCTATTTCGGCATCGACGAGCTCCTGAACGAGCAGAGCGCCGCGCGCGTATGGGAGCAGGCCAACGCCGTGCTGG
CAACTCCCGAATTGACCGCCCACCGCATCCTCGAAAAGTTTCATGTGAAGGCCGTCTGCACCACCGACGACCCCACCGAC
GACCTGGCCGCGCACCAGGCTATCGCGGCGTCCGGCCTCGCGACCAAGGTCTTTCCCACCTTCCGCCCCGACAAAGCTCT
GCACGTTCACGCGCCCGAGCTGTTTAATCCCTGGGTGGACCGCTTGCAGGTAGCCGCCGACACCCACATCTCGACCATGG
CGGAGTTCCTGGACGCCATCAAGAAGCGGCACGACTTCTTCCACGCCATGGGCGGCCGCCTCAGCGATCACGGAATCAAT
CACGCCTTCAGCGATTTTCCAAGCGAGCACGAGGCCGCGCGCATCTTCGGACGCGCGCGCTGCGGCCACGCCGCCACCAG
CGAGGAGCACGGCAAATTCGCGGCCTACATGATGCTCGTCTTCGGCCGCCTGGACGCCGAAAAGGGCTGGACCAAGCAAC
TCCACCTGGGCGCGCGCCGCAATAACAGCACCCGCCGCTTCCGCGAGCTCGGCGCCGACACCGGCTGGGATTCGATCGGC
GACTGGCCGCAGGCCGACGCCCTCGGTACCTACCTGGACCGCCTGGACCTGGAGAATGCCCTTCCCAAAACCGTAATCTA
TAACCTCAATCCCGCCGACAACTATGTGATCGCCACCATGATCGGCAATTTCCAGGATGGGGTCACGGCAGGCAAGGTGC
AGTTCGGCAGCGGCTGGTGGTTCCTGGATCAAAAGGAAGCCATGCAGTGGCAGATGAATGCGCTCTCCAACTGCGGCATG
TTCTCGAAGTTTCTCGGCATGCTGACGGACTCGCGCTCTTTTATGAGCTATCCCCGGCACGAGTATTTCCGGCGCGTGCT
CTGCGACCTCTTCGGACGTGACGTGGAGAACGGGGAGTTACCCGATAATGACGAACTGATTGGTCCGGTGATCCGGGATA
TCTGCTACGGCAATGCGCAGCGGTTCCTGGGCTTGAACGTCTAA

Upstream 100 bases:

>100_bases
GAGCAGACAGACAGCAGGCAGCCTCTTCATTTTGCTCTCATTATCGTACGAACTCCAAAAGCCCGGTGAAGTGTGATTCA
ATCAGCTTTTACCGCTCTAT

Downstream 100 bases:

>100_bases
GAACGCGTCAGACTACGAGATCGCTTCGTGACGTGTGCGGCTCCCATCAGAGCCGCGACCGTTAGGGAGCGATCTCTAGG
AATCACGTCAGATTAAGCTT

Product: glucuronate isomerase

Products: NA

Alternate protein names: Glucuronate isomerase; Uronic isomerase

Number of amino acids: Translated: 467; Mature: 466

Protein sequence:

>467_residues
MSFIHDDFLLSSKTARRFYHTFAEDQPILDYHCHLPPQDVAANRQFKDLFEIWLEGDHYKWRAMRANGVPESHCTGNAPA
YEKFMAWAKTVPATLRNPLYHWTHLELKRYFGIDELLNEQSAARVWEQANAVLATPELTAHRILEKFHVKAVCTTDDPTD
DLAAHQAIAASGLATKVFPTFRPDKALHVHAPELFNPWVDRLQVAADTHISTMAEFLDAIKKRHDFFHAMGGRLSDHGIN
HAFSDFPSEHEAARIFGRARCGHAATSEEHGKFAAYMMLVFGRLDAEKGWTKQLHLGARRNNSTRRFRELGADTGWDSIG
DWPQADALGTYLDRLDLENALPKTVIYNLNPADNYVIATMIGNFQDGVTAGKVQFGSGWWFLDQKEAMQWQMNALSNCGM
FSKFLGMLTDSRSFMSYPRHEYFRRVLCDLFGRDVENGELPDNDELIGPVIRDICYGNAQRFLGLNV

Sequences:

>Translated_467_residues
MSFIHDDFLLSSKTARRFYHTFAEDQPILDYHCHLPPQDVAANRQFKDLFEIWLEGDHYKWRAMRANGVPESHCTGNAPA
YEKFMAWAKTVPATLRNPLYHWTHLELKRYFGIDELLNEQSAARVWEQANAVLATPELTAHRILEKFHVKAVCTTDDPTD
DLAAHQAIAASGLATKVFPTFRPDKALHVHAPELFNPWVDRLQVAADTHISTMAEFLDAIKKRHDFFHAMGGRLSDHGIN
HAFSDFPSEHEAARIFGRARCGHAATSEEHGKFAAYMMLVFGRLDAEKGWTKQLHLGARRNNSTRRFRELGADTGWDSIG
DWPQADALGTYLDRLDLENALPKTVIYNLNPADNYVIATMIGNFQDGVTAGKVQFGSGWWFLDQKEAMQWQMNALSNCGM
FSKFLGMLTDSRSFMSYPRHEYFRRVLCDLFGRDVENGELPDNDELIGPVIRDICYGNAQRFLGLNV
>Mature_466_residues
SFIHDDFLLSSKTARRFYHTFAEDQPILDYHCHLPPQDVAANRQFKDLFEIWLEGDHYKWRAMRANGVPESHCTGNAPAY
EKFMAWAKTVPATLRNPLYHWTHLELKRYFGIDELLNEQSAARVWEQANAVLATPELTAHRILEKFHVKAVCTTDDPTDD
LAAHQAIAASGLATKVFPTFRPDKALHVHAPELFNPWVDRLQVAADTHISTMAEFLDAIKKRHDFFHAMGGRLSDHGINH
AFSDFPSEHEAARIFGRARCGHAATSEEHGKFAAYMMLVFGRLDAEKGWTKQLHLGARRNNSTRRFRELGADTGWDSIGD
WPQADALGTYLDRLDLENALPKTVIYNLNPADNYVIATMIGNFQDGVTAGKVQFGSGWWFLDQKEAMQWQMNALSNCGMF
SKFLGMLTDSRSFMSYPRHEYFRRVLCDLFGRDVENGELPDNDELIGPVIRDICYGNAQRFLGLNV

Specific function: Hexuronate conversion to KDG. [C]

COG id: COG1904

COG function: function code G; Glucuronate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uronate isomerase family

Homologues:

Organism=Escherichia coli, GI2367192, Length=467, Percent_Identity=48.6081370449679, Blast_Score=469, Evalue=1e-133,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UXAC_SOLUE (Q01VN6)

Other databases:

- EMBL:   CP000473
- RefSeq:   YP_826564.1
- ProteinModelPortal:   Q01VN6
- SMR:   Q01VN6
- STRING:   Q01VN6
- GeneID:   4426484
- GenomeReviews:   CP000473_GR
- KEGG:   sus:Acid_5330
- NMPDR:   fig|234267.9.peg.5061
- eggNOG:   COG1904
- HOGENOM:   HBG297087
- OMA:   AWAKTVP
- PhylomeDB:   Q01VN6
- ProtClustDB:   PRK02925
- HAMAP:   MF_00675
- InterPro:   IPR003766
- InterPro:   IPR023177
- Gene3D:   G3DSA:1.10.2020.10

Pfam domain/function: PF02614 UxaC

EC number: =5.3.1.12

Molecular weight: Translated: 53199; Mature: 53067

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFIHDDFLLSSKTARRFYHTFAEDQPILDYHCHLPPQDVAANRQFKDLFEIWLEGDHYK
CCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHCCCHHHHHHHHHHCCCCEE
WRAMRANGVPESHCTGNAPAYEKFMAWAKTVPATLRNPLYHWTHLELKRYFGIDELLNEQ
EEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHCCHHHHHCHH
SAARVWEQANAVLATPELTAHRILEKFHVKAVCTTDDPTDDLAAHQAIAASGLATKVFPT
HHHHHHHHCCCEEECCCHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHCCCHHHCCCC
FRPDKALHVHAPELFNPWVDRLQVAADTHISTMAEFLDAIKKRHDFFHAMGGRLSDHGIN
CCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
HAFSDFPSEHEAARIFGRARCGHAATSEEHGKFAAYMMLVFGRLDAEKGWTKQLHLGARR
HHHHCCCCHHHHHHHHHHHHCCCCCCCHHCCHHHHHHHHHHHHCCCCCCCCHHHHCCCCC
NNSTRRFRELGADTGWDSIGDWPQADALGTYLDRLDLENALPKTVIYNLNPADNYVIATM
CCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEE
IGNFQDGVTAGKVQFGSGWWFLDQKEAMQWQMNALSNCGMFSKFLGMLTDSRSFMSYPRH
CCCCCCCCCCCEEEECCCEEEECHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHCCCHH
EYFRRVLCDLFGRDVENGELPDNDELIGPVIRDICYGNAQRFLGLNV
HHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHCCCCC
>Mature Secondary Structure 
SFIHDDFLLSSKTARRFYHTFAEDQPILDYHCHLPPQDVAANRQFKDLFEIWLEGDHYK
CCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHCCCHHHHHHHHHHCCCCEE
WRAMRANGVPESHCTGNAPAYEKFMAWAKTVPATLRNPLYHWTHLELKRYFGIDELLNEQ
EEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHCCHHHHHCHH
SAARVWEQANAVLATPELTAHRILEKFHVKAVCTTDDPTDDLAAHQAIAASGLATKVFPT
HHHHHHHHCCCEEECCCHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHCCCHHHCCCC
FRPDKALHVHAPELFNPWVDRLQVAADTHISTMAEFLDAIKKRHDFFHAMGGRLSDHGIN
CCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
HAFSDFPSEHEAARIFGRARCGHAATSEEHGKFAAYMMLVFGRLDAEKGWTKQLHLGARR
HHHHCCCCHHHHHHHHHHHHCCCCCCCHHCCHHHHHHHHHHHHCCCCCCCCHHHHCCCCC
NNSTRRFRELGADTGWDSIGDWPQADALGTYLDRLDLENALPKTVIYNLNPADNYVIATM
CCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEE
IGNFQDGVTAGKVQFGSGWWFLDQKEAMQWQMNALSNCGMFSKFLGMLTDSRSFMSYPRH
CCCCCCCCCCCEEEECCCEEEECHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHCCCHH
EYFRRVLCDLFGRDVENGELPDNDELIGPVIRDICYGNAQRFLGLNV
HHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA