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The map label for this gene is ubiE [C]

Identifier: 116624352

GI number: 116624352

Start: 6609648

End: 6610562

Strand: Reverse

Name: ubiE [C]

Synonym: Acid_5272

Alternate gene names: 116624352

Gene position: 6610562-6609648 (Counterclockwise)

Preceding gene: 116624355

Following gene: 116624349

Centisome position: 66.33

GC content: 61.42

Gene sequence:

>915_bases
ATGGCGTCAATCCTGAAATCGCTGCGGCTGGCAGCCGACCCCAACCGTTTGCGGATGCTTCTTCTGCTGGAGCGCGAAGA
ATTGTCTGTTGCGGAACTGCAGGAGATTCTGGCGCGGGGGCAGAGCCAGATTTCCACCCACCTTGCGCAGCTCAAGCAGG
CCGGCCTGGTGGAAGACCGGCGTATGGGAAAGAACGCTTTCTACCGGCTGACGGCTCCCGCCGAATTGATGGAATTGCTG
CGCCAGGCGCACGGTGAAATTCCGGAAACCGCGCAGGACCAGGAGGCGTTGCGGCTGGCGCTGCGCAAGCGCACCGACAA
CATGCGGCGCTATTTCGACGAGCTGGCCGGCAAATTCGGGCGGCAGTACGTGCCGGGCAGGTCCTGGAAGGGGATCGCGG
AGGCGCTCTTGAAGCTGATGCCGCCCATGGTGATCGCCGATCTCGGGGCAGGGGAAGGCACCATATCGCAATTGATGGCC
CAGCGCGCCAAACGCGTGATCGCGATCGATAACTCCGAGAAGATGGTCGAGTTCGGCGCGGAATTGGCGCGCAAGCACGG
CATCGCCAATCTGGAATACCGGCTCGGGGACCTGGAAGATGTACCGATTCGCACGGGTACGGTGGATTTGGCGTTCCTGA
GCCAGGCGCTGCATCACGCGGTGCATCCGGAGCGGGCAATTGCGGAGGCGTCGCGCATTCTCAAGAAGGGCGGCAGAATC
GCGATTCTCGATCTCAGCAGGCATCATTTCGAGGAGGCGCGCGAGATGTACGCAGACCTCTGGCTGGGCTTCACGGAATT
GGAAATCGAGCGCTTCTTGAAGGGTGCGGGATTCAAGAATGTAGAGACGGCGGTGGTGCACCGGGAGCAGGAAGCACCCT
ACTTTGAGACGATTCTGGCGACGGGCGAGAAATGA

Upstream 100 bases:

>100_bases
GGCGTCGGAGAGTTTTTCGGTTGCGGTGCCCATAATCGATTTTCTTTTATTCCCTCGTATCAATAAATCTTGATAGATTG
ATATTAGACCCTTTGGACCT

Downstream 100 bases:

>100_bases
AAAGGAGAACTCATGGCCGACGGCTGCGAGGAACGCACAGAACGCGAAATGCGCATTGAACAGGAGAAGCTGAAGGATCG
CGAAGACCGTATCGACCGGG

Product: transcriptional regulator

Products: S-Adenosyl-L-Homocysteine; @OCTA02.txt*2- Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol!; Menaquinol. [C]

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MASILKSLRLAADPNRLRMLLLLEREELSVAELQEILARGQSQISTHLAQLKQAGLVEDRRMGKNAFYRLTAPAELMELL
RQAHGEIPETAQDQEALRLALRKRTDNMRRYFDELAGKFGRQYVPGRSWKGIAEALLKLMPPMVIADLGAGEGTISQLMA
QRAKRVIAIDNSEKMVEFGAELARKHGIANLEYRLGDLEDVPIRTGTVDLAFLSQALHHAVHPERAIAEASRILKKGGRI
AILDLSRHHFEEAREMYADLWLGFTELEIERFLKGAGFKNVETAVVHREQEAPYFETILATGEK

Sequences:

>Translated_304_residues
MASILKSLRLAADPNRLRMLLLLEREELSVAELQEILARGQSQISTHLAQLKQAGLVEDRRMGKNAFYRLTAPAELMELL
RQAHGEIPETAQDQEALRLALRKRTDNMRRYFDELAGKFGRQYVPGRSWKGIAEALLKLMPPMVIADLGAGEGTISQLMA
QRAKRVIAIDNSEKMVEFGAELARKHGIANLEYRLGDLEDVPIRTGTVDLAFLSQALHHAVHPERAIAEASRILKKGGRI
AILDLSRHHFEEAREMYADLWLGFTELEIERFLKGAGFKNVETAVVHREQEAPYFETILATGEK
>Mature_303_residues
ASILKSLRLAADPNRLRMLLLLEREELSVAELQEILARGQSQISTHLAQLKQAGLVEDRRMGKNAFYRLTAPAELMELLR
QAHGEIPETAQDQEALRLALRKRTDNMRRYFDELAGKFGRQYVPGRSWKGIAEALLKLMPPMVIADLGAGEGTISQLMAQ
RAKRVIAIDNSEKMVEFGAELARKHGIANLEYRLGDLEDVPIRTGTVDLAFLSQALHHAVHPERAIAEASRILKKGGRIA
ILDLSRHHFEEAREMYADLWLGFTELEIERFLKGAGFKNVETAVVHREQEAPYFETILATGEK

Specific function: Methyltransferase Required For The Conversion Of Dimethylmenaquinone (Dmkh2) To Menaquinone (Mkh2) And The Conversion Of 2-Polyprenyl-6-Methoxy-1,4-Benzoquinol (Ddmqh2) To 2-Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol (Dmqh2). [C]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013216
- InterPro:   IPR005149
- InterPro:   IPR011991 [H]

Pfam domain/function: PF08241 Methyltransf_11; PF03551 PadR [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 34256; Mature: 34125

Theoretical pI: Translated: 7.38; Mature: 7.38

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASILKSLRLAADPNRLRMLLLLEREELSVAELQEILARGQSQISTHLAQLKQAGLVEDR
CHHHHHHHHHHCCHHHHEEHHEECCCCCCHHHHHHHHHHCHHHHHHHHHHHHHCCCHHHH
RMGKNAFYRLTAPAELMELLRQAHGEIPETAQDQEALRLALRKRTDNMRRYFDELAGKFG
HCCCCCEEEECCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RQYVPGRSWKGIAEALLKLMPPMVIADLGAGEGTISQLMAQRAKRVIAIDNSEKMVEFGA
CCCCCCCCHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHCEEEEECCCHHHHHHHH
ELARKHGIANLEYRLGDLEDVPIRTGTVDLAFLSQALHHAVHPERAIAEASRILKKGGRI
HHHHHCCCCCCCEECCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCE
AILDLSRHHFEEAREMYADLWLGFTELEIERFLKGAGFKNVETAVVHREQEAPYFETILA
EEEECHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCHHHHHHH
TGEK
CCCC
>Mature Secondary Structure 
ASILKSLRLAADPNRLRMLLLLEREELSVAELQEILARGQSQISTHLAQLKQAGLVEDR
HHHHHHHHHHCCHHHHEEHHEECCCCCCHHHHHHHHHHCHHHHHHHHHHHHHCCCHHHH
RMGKNAFYRLTAPAELMELLRQAHGEIPETAQDQEALRLALRKRTDNMRRYFDELAGKFG
HCCCCCEEEECCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RQYVPGRSWKGIAEALLKLMPPMVIADLGAGEGTISQLMAQRAKRVIAIDNSEKMVEFGA
CCCCCCCCHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHCEEEEECCCHHHHHHHH
ELARKHGIANLEYRLGDLEDVPIRTGTVDLAFLSQALHHAVHPERAIAEASRILKKGGRI
HHHHHCCCCCCCEECCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCE
AILDLSRHHFEEAREMYADLWLGFTELEIERFLKGAGFKNVETAVVHREQEAPYFETILA
EEEECHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCHHHHHHH
TGEK
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-Methionine; 2-Polyprenyl-6- Methoxy-1,4-Benzoquinol; Demethylmenaquinol [C]

Specific reaction: S-Adenosyl-L-Methionine + @OCTA02.txt*2-Polyprenyl-6- Methoxy-1,4-Benzoquinol! = S-Adenosyl-L-Homocysteine + 2- Polyprenyl-3-Methyl-6-Methoxy -1,4-Benzoquinol S-Adenosyl-L-Methionine + Demethylmenaquinol = S-Adenosyl-L-Homocysteine + Menaquinol. [C]

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2155856 [H]