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The map label for this gene is mrp [C]

Identifier: 116624312

GI number: 116624312

Start: 6564407

End: 6565231

Strand: Reverse

Name: mrp [C]

Synonym: Acid_5230

Alternate gene names: 116624312

Gene position: 6565231-6564407 (Counterclockwise)

Preceding gene: 116624319

Following gene: 116624310

Centisome position: 65.88

GC content: 63.64

Gene sequence:

>825_bases
ATGTCTCCCAATCAACCCGGCCAAGTGCCGAAACTGCCCATTCCAGGCGTGAAGAATCTGATCGCTGTCGGCTCCGGAAA
GGGAGGCGTCGGTAAAACCACCGTGTCGGTGAACCTCGCGGTCGGTCTCGCCGCGCTCGGTTACAAGGTTGGACTCATGG
ACGCCGATGTCTACGGCCCCAACGTGCCCCTCATGATGGGCATCAACCAGACCCCGATGGCGATCGGCGAACGCATTCAG
CCGCTCGAACAGTACGGCGTCAAGCTCATGTCGATGGGCTTCCTCAGCCCCGGCGACAAGCCCCTCGTCTGGCGCGGCCC
CATGCTCCACTCCGTCATTCAGCAATTCCTCCGCGGCGTCGATTGGGGTCAACTCGATTACCTCGTCATCGACCTCCCCC
CCGGCACCGGCGACGTGCAACTCTCCCTCATCCAGACCGCTCCCGTGACCGGCGCCATCGTCGTCACCACTCCGTCCGAT
GTTTCGCTCGAGGACGCCCGCAAAGCCGTCATGATGTTCCACCAGGTGAAGGTGCCCATCCTCGGCATCGTCGAGAACAT
GAGCTATCTCGCCTGCCCCCACTGCAACGAGCGCATCGACGTCTTCAGCCACGGCGGCGGCCGCCGCACCGCTCAGGAGA
TGCAAGTCCACTTCCTCGCCGAACTCCCGCTCGACCCCGAAGTCCGCATCGGCGGCGATAGCGGCCTGCCCATCGTGCAA
CGCAAAGGCCAGGGCGAACCCTTCCTCGAACTGGCCCGCCAGGCCGTCGCCCGCACCGAAGAGGTCGCCAAAGACGAAGG
CCCCAAAATCGAAATCACCGACTAA

Upstream 100 bases:

>100_bases
TCGGCACCCGATCACGGACGGTTCTCCCTTGAAACAATGCATTGTACACCCTCGCGGACTTCCATTGTTGGAATTGCGCT
GCTGTTACCATAGTGGCTGA

Downstream 100 bases:

>100_bases
CCATAAGCGATGACCCCGCGTTTCACTGACTCGCCAGAGACATCCCGTTGCAATTCGATTACTATGTTCTCATTCGTTCA
TCTGAGGGAGAACCACCATG

Product: cobyrinic acid a,c-diamide synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 274; Mature: 273

Protein sequence:

>274_residues
MSPNQPGQVPKLPIPGVKNLIAVGSGKGGVGKTTVSVNLAVGLAALGYKVGLMDADVYGPNVPLMMGINQTPMAIGERIQ
PLEQYGVKLMSMGFLSPGDKPLVWRGPMLHSVIQQFLRGVDWGQLDYLVIDLPPGTGDVQLSLIQTAPVTGAIVVTTPSD
VSLEDARKAVMMFHQVKVPILGIVENMSYLACPHCNERIDVFSHGGGRRTAQEMQVHFLAELPLDPEVRIGGDSGLPIVQ
RKGQGEPFLELARQAVARTEEVAKDEGPKIEITD

Sequences:

>Translated_274_residues
MSPNQPGQVPKLPIPGVKNLIAVGSGKGGVGKTTVSVNLAVGLAALGYKVGLMDADVYGPNVPLMMGINQTPMAIGERIQ
PLEQYGVKLMSMGFLSPGDKPLVWRGPMLHSVIQQFLRGVDWGQLDYLVIDLPPGTGDVQLSLIQTAPVTGAIVVTTPSD
VSLEDARKAVMMFHQVKVPILGIVENMSYLACPHCNERIDVFSHGGGRRTAQEMQVHFLAELPLDPEVRIGGDSGLPIVQ
RKGQGEPFLELARQAVARTEEVAKDEGPKIEITD
>Mature_273_residues
SPNQPGQVPKLPIPGVKNLIAVGSGKGGVGKTTVSVNLAVGLAALGYKVGLMDADVYGPNVPLMMGINQTPMAIGERIQP
LEQYGVKLMSMGFLSPGDKPLVWRGPMLHSVIQQFLRGVDWGQLDYLVIDLPPGTGDVQLSLIQTAPVTGAIVVTTPSDV
SLEDARKAVMMFHQVKVPILGIVENMSYLACPHCNERIDVFSHGGGRRTAQEMQVHFLAELPLDPEVRIGGDSGLPIVQR
KGQGEPFLELARQAVARTEEVAKDEGPKIEITD

Specific function: Not Known. [C]

COG id: COG0489

COG function: function code D; ATPases involved in chromosome partitioning

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Mrp/NBP35 ATP-binding proteins family [H]

Homologues:

Organism=Homo sapiens, GI157384956, Length=252, Percent_Identity=48.4126984126984, Blast_Score=234, Evalue=5e-62,
Organism=Homo sapiens, GI6912540, Length=237, Percent_Identity=43.0379746835443, Blast_Score=182, Evalue=2e-46,
Organism=Homo sapiens, GI118572611, Length=228, Percent_Identity=42.9824561403509, Blast_Score=181, Evalue=6e-46,
Organism=Escherichia coli, GI87082045, Length=257, Percent_Identity=47.4708171206226, Blast_Score=227, Evalue=7e-61,
Organism=Caenorhabditis elegans, GI25143050, Length=264, Percent_Identity=39.7727272727273, Blast_Score=175, Evalue=3e-44,
Organism=Saccharomyces cerevisiae, GI6322188, Length=284, Percent_Identity=38.0281690140845, Blast_Score=189, Evalue=3e-49,
Organism=Saccharomyces cerevisiae, GI6321347, Length=266, Percent_Identity=37.593984962406, Blast_Score=158, Evalue=1e-39,
Organism=Drosophila melanogaster, GI221511043, Length=230, Percent_Identity=46.5217391304348, Blast_Score=221, Evalue=4e-58,
Organism=Drosophila melanogaster, GI24667611, Length=222, Percent_Identity=43.6936936936937, Blast_Score=182, Evalue=2e-46,
Organism=Drosophila melanogaster, GI19921440, Length=254, Percent_Identity=37.7952755905512, Blast_Score=139, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019591
- InterPro:   IPR000808 [H]

Pfam domain/function: PF10609 ParA [H]

EC number: NA

Molecular weight: Translated: 29345; Mature: 29213

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: PS01215 MRP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPNQPGQVPKLPIPGVKNLIAVGSGKGGVGKTTVSVNLAVGLAALGYKVGLMDADVYGP
CCCCCCCCCCCCCCCCCCCEEEECCCCCCCCEEEEEEEHHHHHHHHCEEEEEEECCCCCC
NVPLMMGINQTPMAIGERIQPLEQYGVKLMSMGFLSPGDKPLVWRGPMLHSVIQQFLRGV
CCCEEECCCCCCHHHHHHCCHHHHHCHHEEECCCCCCCCCCEEEECHHHHHHHHHHHHCC
DWGQLDYLVIDLPPGTGDVQLSLIQTAPVTGAIVVTTPSDVSLEDARKAVMMFHQVKVPI
CCCCEEEEEEECCCCCCCEEEEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCH
LGIVENMSYLACPHCNERIDVFSHGGGRRTAQEMQVHFLAELPLDPEVRIGGDSGLPIVQ
HHHHHCCCEEECCCCCCCEEEEECCCCCCCHHHHHEEEEEECCCCCCEEECCCCCCCEEE
RKGQGEPFLELARQAVARTEEVAKDEGPKIEITD
ECCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECC
>Mature Secondary Structure 
SPNQPGQVPKLPIPGVKNLIAVGSGKGGVGKTTVSVNLAVGLAALGYKVGLMDADVYGP
CCCCCCCCCCCCCCCCCCEEEECCCCCCCCEEEEEEEHHHHHHHHCEEEEEEECCCCCC
NVPLMMGINQTPMAIGERIQPLEQYGVKLMSMGFLSPGDKPLVWRGPMLHSVIQQFLRGV
CCCEEECCCCCCHHHHHHCCHHHHHCHHEEECCCCCCCCCCEEEECHHHHHHHHHHHHCC
DWGQLDYLVIDLPPGTGDVQLSLIQTAPVTGAIVVTTPSDVSLEDARKAVMMFHQVKVPI
CCCCEEEEEEECCCCCCCEEEEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCH
LGIVENMSYLACPHCNERIDVFSHGGGRRTAQEMQVHFLAELPLDPEVRIGGDSGLPIVQ
HHHHHCCCEEECCCCCCCEEEEECCCCCCCHHHHHEEEEEECCCCCCEEECCCCCCCEEE
RKGQGEPFLELARQAVARTEEVAKDEGPKIEITD
ECCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]