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The map label for this gene is atoS [C]

Identifier: 116622957

GI number: 116622957

Start: 4892837

End: 4894897

Strand: Reverse

Name: atoS [C]

Synonym: Acid_3859

Alternate gene names: 116622957

Gene position: 4894897-4892837 (Counterclockwise)

Preceding gene: 116622959

Following gene: 116622956

Centisome position: 49.12

GC content: 62.74

Gene sequence:

>2061_bases
ATGGGCCTGGCTTATTCTGGCGATCAGGACGGACCGCGTCTCGCCGCGCTGCGTAACTACCGTGTTCTCGATACCTTGGA
AGACGCTGCCTTCGATCGCGTAACCGAGATGACCGCCCGCCTTTTCCAGGCGCCCATAGCGGTCATTTCCTTCGTGGAAC
AGTCCCGCCTCTTTTTTAAGTCTCATTTCGGGCTGGAAATCTCCCAGATCTCGTCCCATGGGTCGTTCTGCGCCCACACC
ATTCTGTCCAACGACGTCATGGTTGTGCCCGACGCTGCCAAGGACCCGCGCTTCGCCTCAGCGCCCGTCACCGTCGGTGG
CCTTCGTATCCGTTTCTATGCCGGCGCTCCCCTCATCACCCCCGCGGGCTACCGGCTCGGCGCACTCGCCGTCATGGATA
CCCGCCCCCGCCCCGCGCTAACCGAAGACGAGACCGCGACGCTTGTGGATCTCGCCGGCCTTGTCATGCACGATCTGAAC
GGCCGTCAGGAGCTGGCGCGCGCCCGCAACCTACCCGGCATGGCCGCTGAGGCAGAGGCCAAGTTTACCGCCTTCATGGA
ATCGGCCTCCCAGGCGATCATCGCCATCAATCATCACGGCGAAATCGAGGTCGTGAACCATAAGGCCGAGGAGCTCTTCG
GCTACGTGCGTGAAGAAATGGTCGGCCAGCGCCTCGAGCTGCTCCTCCCCGACTCCCTCCGCCACGCTCACGCCGCTCAT
CGAAAGGATTTCTTCGCCCACCCACACGCCCGCCCCATGGGGATAGGCATGGACTTGGCCGGTCAGCGCAAGAGCGGCCA
CCAGTTCCCGGTCGAGATCAGCCTCAATCACGTCGAGGTCGGCAGCCGCGCCCTGGCCTTCGCCTTCATCACCGACATCA
CCGCCCGCCTGCGTCTCGAGCAGCAGTTGCGGCAGTCACAGAAGCTCGAGGCCGTCGGCCAGCTCGCCGGCGGAGTGGCC
CACGATTTCAACAACCTCCTCACCGTCATCCACGGTTACAGCTCCATGTCGCTCGATTCGCTCGCGGCCGACAGCCCTCT
GCGGGAACCCATCGAAGAGATCGAAAAGGCTGCCGTCAGCGCCGCCTCTCTCACCCGTCAGTTGCTTGCCTTCAGCCGGC
GCAATGTGGTCCGCCCTCAGATCCTCAACCTCAACACAGTCATCAGCCACATGCAAAAGATGCTCGTCCGCGTCCTCGGG
GAAGACGTCGAACTCATCATGGAAATGGGCGCCGCCCTTGACACCATCCGCGCCGATCCCGGCCTGATCGAGCAGATTCT
GATGAACCTCGCAGTCAATTCCCGAGATGCCATGCCGCACGGCGGCAAACTCATCCTCGAGACCGCCAACCTCTACCTCG
ACAAGGAATACGCCGGCGCCCACCTCGCCGTCAAAACCGGCCCCCACGCCATGCTCGCCGTCACCGATACCGGCAGCGGC
ATGAGCGAGGAAATCCGCTCCCGCATTTTCGAACCCTTCTTCACCACCAAGCCGCAGGGGCAGGGAACGGGCCTCGGCCT
AGCCACCGTCTACGGCATCGTCCAGCAGATGGAGGGTTCCATCTGGGTTTACAGCGAACCCGGTAAAGGCACTACTTTCA
AGATCCTGTTTCCGTCCGCCGAGAAGGGCGAACTCGCAGACTCCGCGGCACAGCCGCGACAGGTTGATACGCGGGGCAAG
GAAGGCATCCTGCTCGTTGAAGACGAGAGCGCCGTCCGCAAATTCGTCCGCGCCCTCCTGGAACGCCAGGGCTACACTGT
CTTCGAAGCGGCCGATTCCGATGCCGCCTTCAAAATTGCTAACGATCCGGCCGCGACATTCGACCTCCTCCTCACCGACG
TCGTCATGCCCCGCATGAACGGCCCCCAGATCGCCGCCCAAATCGAAGCAGTCCGTCCCGGCCTGCGCGTCCTCTACATG
TCCGGCTATACCGACCGCACCATCCACCTCCACGACCAAATCGGCATCCACTCCAATTTCATCCAAAAACCCTTCACTCC
CGCCGGCCTCGCCCAAAAACTCCGCGAACTCCTCACCTCCTCCTCCGACGCCCAGGCATAA

Upstream 100 bases:

>100_bases
CCTGCCTGCTGTTTTCACGTGTATCTTTCGGGTATTACAATTTCTTTCGATTTCTTTTTGCTCTTTTCGTCGCGTATTTC
GTACAATCCAATCAGCACTC

Downstream 100 bases:

>100_bases
GACAGACTGAGTGGGACAGGCAATCCTGCGTTCGCCTGCTTGCTCCGCACCGAGGCGGCCGTACTTGAAAGACGGTGCAC
GCAAGCCCGAATCCGGCCGT

Product: PAS/PAC sensor hybrid histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 686; Mature: 685

Protein sequence:

>686_residues
MGLAYSGDQDGPRLAALRNYRVLDTLEDAAFDRVTEMTARLFQAPIAVISFVEQSRLFFKSHFGLEISQISSHGSFCAHT
ILSNDVMVVPDAAKDPRFASAPVTVGGLRIRFYAGAPLITPAGYRLGALAVMDTRPRPALTEDETATLVDLAGLVMHDLN
GRQELARARNLPGMAAEAEAKFTAFMESASQAIIAINHHGEIEVVNHKAEELFGYVREEMVGQRLELLLPDSLRHAHAAH
RKDFFAHPHARPMGIGMDLAGQRKSGHQFPVEISLNHVEVGSRALAFAFITDITARLRLEQQLRQSQKLEAVGQLAGGVA
HDFNNLLTVIHGYSSMSLDSLAADSPLREPIEEIEKAAVSAASLTRQLLAFSRRNVVRPQILNLNTVISHMQKMLVRVLG
EDVELIMEMGAALDTIRADPGLIEQILMNLAVNSRDAMPHGGKLILETANLYLDKEYAGAHLAVKTGPHAMLAVTDTGSG
MSEEIRSRIFEPFFTTKPQGQGTGLGLATVYGIVQQMEGSIWVYSEPGKGTTFKILFPSAEKGELADSAAQPRQVDTRGK
EGILLVEDESAVRKFVRALLERQGYTVFEAADSDAAFKIANDPAATFDLLLTDVVMPRMNGPQIAAQIEAVRPGLRVLYM
SGYTDRTIHLHDQIGIHSNFIQKPFTPAGLAQKLRELLTSSSDAQA

Sequences:

>Translated_686_residues
MGLAYSGDQDGPRLAALRNYRVLDTLEDAAFDRVTEMTARLFQAPIAVISFVEQSRLFFKSHFGLEISQISSHGSFCAHT
ILSNDVMVVPDAAKDPRFASAPVTVGGLRIRFYAGAPLITPAGYRLGALAVMDTRPRPALTEDETATLVDLAGLVMHDLN
GRQELARARNLPGMAAEAEAKFTAFMESASQAIIAINHHGEIEVVNHKAEELFGYVREEMVGQRLELLLPDSLRHAHAAH
RKDFFAHPHARPMGIGMDLAGQRKSGHQFPVEISLNHVEVGSRALAFAFITDITARLRLEQQLRQSQKLEAVGQLAGGVA
HDFNNLLTVIHGYSSMSLDSLAADSPLREPIEEIEKAAVSAASLTRQLLAFSRRNVVRPQILNLNTVISHMQKMLVRVLG
EDVELIMEMGAALDTIRADPGLIEQILMNLAVNSRDAMPHGGKLILETANLYLDKEYAGAHLAVKTGPHAMLAVTDTGSG
MSEEIRSRIFEPFFTTKPQGQGTGLGLATVYGIVQQMEGSIWVYSEPGKGTTFKILFPSAEKGELADSAAQPRQVDTRGK
EGILLVEDESAVRKFVRALLERQGYTVFEAADSDAAFKIANDPAATFDLLLTDVVMPRMNGPQIAAQIEAVRPGLRVLYM
SGYTDRTIHLHDQIGIHSNFIQKPFTPAGLAQKLRELLTSSSDAQA
>Mature_685_residues
GLAYSGDQDGPRLAALRNYRVLDTLEDAAFDRVTEMTARLFQAPIAVISFVEQSRLFFKSHFGLEISQISSHGSFCAHTI
LSNDVMVVPDAAKDPRFASAPVTVGGLRIRFYAGAPLITPAGYRLGALAVMDTRPRPALTEDETATLVDLAGLVMHDLNG
RQELARARNLPGMAAEAEAKFTAFMESASQAIIAINHHGEIEVVNHKAEELFGYVREEMVGQRLELLLPDSLRHAHAAHR
KDFFAHPHARPMGIGMDLAGQRKSGHQFPVEISLNHVEVGSRALAFAFITDITARLRLEQQLRQSQKLEAVGQLAGGVAH
DFNNLLTVIHGYSSMSLDSLAADSPLREPIEEIEKAAVSAASLTRQLLAFSRRNVVRPQILNLNTVISHMQKMLVRVLGE
DVELIMEMGAALDTIRADPGLIEQILMNLAVNSRDAMPHGGKLILETANLYLDKEYAGAHLAVKTGPHAMLAVTDTGSGM
SEEIRSRIFEPFFTTKPQGQGTGLGLATVYGIVQQMEGSIWVYSEPGKGTTFKILFPSAEKGELADSAAQPRQVDTRGKE
GILLVEDESAVRKFVRALLERQGYTVFEAADSDAAFKIANDPAATFDLLLTDVVMPRMNGPQIAAQIEAVRPGLRVLYMS
GYTDRTIHLHDQIGIHSNFIQKPFTPAGLAQKLRELLTSSSDAQA

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=361, Percent_Identity=30.4709141274238, Blast_Score=146, Evalue=3e-36,
Organism=Escherichia coli, GI1790436, Length=253, Percent_Identity=30.0395256916996, Blast_Score=113, Evalue=4e-26,
Organism=Escherichia coli, GI1788713, Length=227, Percent_Identity=28.6343612334802, Blast_Score=84, Evalue=4e-17,
Organism=Escherichia coli, GI145693157, Length=341, Percent_Identity=23.7536656891496, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI48994928, Length=543, Percent_Identity=21.1786372007366, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1790300, Length=248, Percent_Identity=28.6290322580645, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1786912, Length=256, Percent_Identity=26.171875, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI87081921, Length=128, Percent_Identity=27.34375, Blast_Score=63, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 74865; Mature: 74733

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS50112 PAS ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLAYSGDQDGPRLAALRNYRVLDTLEDAAFDRVTEMTARLFQAPIAVISFVEQSRLFFK
CCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SHFGLEISQISSHGSFCAHTILSNDVMVVPDAAKDPRFASAPVTVGGLRIRFYAGAPLIT
HHCCEEEEHHHCCCCHHHHHHHCCCEEEECCCCCCCCCCCCCEEECCEEEEEEECCCEEC
PAGYRLGALAVMDTRPRPALTEDETATLVDLAGLVMHDLNGRQELARARNLPGMAAEAEA
CCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHH
KFTAFMESASQAIIAINHHGEIEVVNHKAEELFGYVREEMVGQRLELLLPDSLRHAHAAH
HHHHHHHCCCCEEEEEECCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
RKDFFAHPHARPMGIGMDLAGQRKSGHQFPVEISLNHVEVGSRALAFAFITDITARLRLE
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECEEECCCHHHHHHHHHHHHHHHHHH
QQLRQSQKLEAVGQLAGGVAHDFNNLLTVIHGYSSMSLDSLAADSPLREPIEEIEKAAVS
HHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCHHHHHCCCHHHHHHHHHHHHHHH
AASLTRQLLAFSRRNVVRPQILNLNTVISHMQKMLVRVLGEDVELIMEMGAALDTIRADP
HHHHHHHHHHHHHCCCCCCHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCC
GLIEQILMNLAVNSRDAMPHGGKLILETANLYLDKEYAGAHLAVKTGPHAMLAVTDTGSG
HHHHHHHHHHHCCCCCCCCCCCEEEEEEECEEEECCCCCCEEEEECCCCEEEEEECCCCC
MSEEIRSRIFEPFFTTKPQGQGTGLGLATVYGIVQQMEGSIWVYSEPGKGTTFKILFPSA
HHHHHHHHHCCCHHCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCEEEEEECCC
EKGELADSAAQPRQVDTRGKEGILLVEDESAVRKFVRALLERQGYTVFEAADSDAAFKIA
CCCCCCCCCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHCCCEEEEECCCCCEEEEC
NDPAATFDLLLTDVVMPRMNGPQIAAQIEAVRPGLRVLYMSGYTDRTIHLHDQIGIHSNF
CCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEEEECCCCCCEEEEECCCCCCHHH
IQKPFTPAGLAQKLRELLTSSSDAQA
HCCCCCHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
GLAYSGDQDGPRLAALRNYRVLDTLEDAAFDRVTEMTARLFQAPIAVISFVEQSRLFFK
CCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SHFGLEISQISSHGSFCAHTILSNDVMVVPDAAKDPRFASAPVTVGGLRIRFYAGAPLIT
HHCCEEEEHHHCCCCHHHHHHHCCCEEEECCCCCCCCCCCCCEEECCEEEEEEECCCEEC
PAGYRLGALAVMDTRPRPALTEDETATLVDLAGLVMHDLNGRQELARARNLPGMAAEAEA
CCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHH
KFTAFMESASQAIIAINHHGEIEVVNHKAEELFGYVREEMVGQRLELLLPDSLRHAHAAH
HHHHHHHCCCCEEEEEECCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
RKDFFAHPHARPMGIGMDLAGQRKSGHQFPVEISLNHVEVGSRALAFAFITDITARLRLE
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECEEECCCHHHHHHHHHHHHHHHHHH
QQLRQSQKLEAVGQLAGGVAHDFNNLLTVIHGYSSMSLDSLAADSPLREPIEEIEKAAVS
HHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCHHHHHCCCHHHHHHHHHHHHHHH
AASLTRQLLAFSRRNVVRPQILNLNTVISHMQKMLVRVLGEDVELIMEMGAALDTIRADP
HHHHHHHHHHHHHCCCCCCHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCC
GLIEQILMNLAVNSRDAMPHGGKLILETANLYLDKEYAGAHLAVKTGPHAMLAVTDTGSG
HHHHHHHHHHHCCCCCCCCCCCEEEEEEECEEEECCCCCCEEEEECCCCEEEEEECCCCC
MSEEIRSRIFEPFFTTKPQGQGTGLGLATVYGIVQQMEGSIWVYSEPGKGTTFKILFPSA
HHHHHHHHHCCCHHCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCEEEEEECCC
EKGELADSAAQPRQVDTRGKEGILLVEDESAVRKFVRALLERQGYTVFEAADSDAAFKIA
CCCCCCCCCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHCCCEEEEECCCCCEEEEC
NDPAATFDLLLTDVVMPRMNGPQIAAQIEAVRPGLRVLYMSGYTDRTIHLHDQIGIHSNF
CCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEEEECCCCCCEEEEECCCCCCHHH
IQKPFTPAGLAQKLRELLTSSSDAQA
HCCCCCHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA