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The map label for this gene is rpe [H]

Identifier: 116622297

GI number: 116622297

Start: 4040611

End: 4041285

Strand: Direct

Name: rpe [H]

Synonym: Acid_3191

Alternate gene names: 116622297

Gene position: 4040611-4041285 (Clockwise)

Preceding gene: 116622296

Following gene: 116622298

Centisome position: 40.55

GC content: 57.63

Gene sequence:

>675_bases
ATGATTGAAATCGTTCCCTCCATCCTGTCTGCCGATTTCGCCAGACTGGCAGATGAAATCGCCCGCGTCGAGCGTGGCGG
TGCGCGTATGCTGCACCTTGACGTGATGGACGGGCATTTCGTGGACAACCTCACGATCGGCCCGCCGGTAGTGGAGTCGG
TCCGGAAAAACACCAGCCTCCACCTGGACGTCCACCTGATGATCGAAAACCCCGAAAGGTACGTGGAATCTTTCGCCCGG
GCGGGGGCCAATTCGATCTCGGTTCACTATGAAGCGGTACGGCATTTGGACGGTGTTCTCGGCCTGATTCGAAAGGCCGG
AGCAATGGCCGGAGTGGTGCTGAATCCAGCCACCCCGGTAGGTGTACTGGAAGATGTCCTGGGAATGGCGGATTACGTGC
TCCTTATGAGCGTGAATCCGGGATTCGGCGGTCAGAAACTCATACCCTACGTGCTGGATAAAGTACGCAAACTCGACAGC
ATGCGTAGGGAGAAGAAGTTAGCGCTGCTGATTGAAATCGATGGCGGCGTCCACAAGGAAAATCTGGCCGAAGTGGTGCG
GGCGGGGTGTGACTGGATCGTCACAGGGTCCGCAATCTTTCACAGTCCGGATCCGGAAGCCACGATGCGTGAGATGCGGG
AAATCGCGGCTCATGCCACCGCGGTCCAGTGTTAA

Upstream 100 bases:

>100_bases
GCCGTTCAGGCGCGTGTGGAGCGGACCGAGCAGCGGCTTCCCGGCCGTGAAGCCGGGGACGGTTTCTATGCTGCTGTGAT
AAAATGCGATATAGCCGTAA

Downstream 100 bases:

>100_bases
TCGTTTGGGTAAGCAGCAGTATTTCTTGGGGTGATTGATTGATTATGGTTCGAAAAGGATTTCGTTTTACCGCCGCGATG
GTCGCGGTTGCGGTGCTTCT

Product: ribulose-5-phosphate 3-epimerase

Products: NA

Alternate protein names: Pentose-5-phosphate 3-epimerase; PPE; R5P3E [H]

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MIEIVPSILSADFARLADEIARVERGGARMLHLDVMDGHFVDNLTIGPPVVESVRKNTSLHLDVHLMIENPERYVESFAR
AGANSISVHYEAVRHLDGVLGLIRKAGAMAGVVLNPATPVGVLEDVLGMADYVLLMSVNPGFGGQKLIPYVLDKVRKLDS
MRREKKLALLIEIDGGVHKENLAEVVRAGCDWIVTGSAIFHSPDPEATMREMREIAAHATAVQC

Sequences:

>Translated_224_residues
MIEIVPSILSADFARLADEIARVERGGARMLHLDVMDGHFVDNLTIGPPVVESVRKNTSLHLDVHLMIENPERYVESFAR
AGANSISVHYEAVRHLDGVLGLIRKAGAMAGVVLNPATPVGVLEDVLGMADYVLLMSVNPGFGGQKLIPYVLDKVRKLDS
MRREKKLALLIEIDGGVHKENLAEVVRAGCDWIVTGSAIFHSPDPEATMREMREIAAHATAVQC
>Mature_224_residues
MIEIVPSILSADFARLADEIARVERGGARMLHLDVMDGHFVDNLTIGPPVVESVRKNTSLHLDVHLMIENPERYVESFAR
AGANSISVHYEAVRHLDGVLGLIRKAGAMAGVVLNPATPVGVLEDVLGMADYVLLMSVNPGFGGQKLIPYVLDKVRKLDS
MRREKKLALLIEIDGGVHKENLAEVVRAGCDWIVTGSAIFHSPDPEATMREMREIAAHATAVQC

Specific function: Unknown

COG id: COG0036

COG function: function code G; Pentose-5-phosphate-3-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribulose-phosphate 3-epimerase family [H]

Homologues:

Organism=Homo sapiens, GI40385883, Length=219, Percent_Identity=41.0958904109589, Blast_Score=160, Evalue=6e-40,
Organism=Homo sapiens, GI219879828, Length=219, Percent_Identity=39.2694063926941, Blast_Score=148, Evalue=4e-36,
Organism=Homo sapiens, GI24307923, Length=174, Percent_Identity=32.183908045977, Blast_Score=93, Evalue=2e-19,
Organism=Escherichia coli, GI1789788, Length=211, Percent_Identity=49.2890995260664, Blast_Score=201, Evalue=4e-53,
Organism=Escherichia coli, GI1790523, Length=226, Percent_Identity=35.3982300884956, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1790754, Length=207, Percent_Identity=30.4347826086957, Blast_Score=102, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17552948, Length=232, Percent_Identity=43.1034482758621, Blast_Score=167, Evalue=5e-42,
Organism=Saccharomyces cerevisiae, GI6322341, Length=224, Percent_Identity=39.7321428571429, Blast_Score=169, Evalue=3e-43,
Organism=Drosophila melanogaster, GI24586301, Length=214, Percent_Identity=40.1869158878505, Blast_Score=155, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000056
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00834 Ribul_P_3_epim [H]

EC number: =5.1.3.1 [H]

Molecular weight: Translated: 24408; Mature: 24408

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: PS01085 RIBUL_P_3_EPIMER_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEIVPSILSADFARLADEIARVERGGARMLHLDVMDGHFVDNLTIGPPVVESVRKNTSL
CCEEHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEECCCCCCCHHHHHHHCCCEE
HLDVHLMIENPERYVESFARAGANSISVHYEAVRHLDGVLGLIRKAGAMAGVVLNPATPV
EEEEEEEEECHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHCEEECCCCCH
GVLEDVLGMADYVLLMSVNPGFGGQKLIPYVLDKVRKLDSMRREKKLALLIEIDGGVHKE
HHHHHHHHHHHEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCHH
NLAEVVRAGCDWIVTGSAIFHSPDPEATMREMREIAAHATAVQC
HHHHHHHCCCCEEEECCEEEECCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIEIVPSILSADFARLADEIARVERGGARMLHLDVMDGHFVDNLTIGPPVVESVRKNTSL
CCEEHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEECCCCCCCHHHHHHHCCCEE
HLDVHLMIENPERYVESFARAGANSISVHYEAVRHLDGVLGLIRKAGAMAGVVLNPATPV
EEEEEEEEECHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHCEEECCCCCH
GVLEDVLGMADYVLLMSVNPGFGGQKLIPYVLDKVRKLDSMRREKKLALLIEIDGGVHKE
HHHHHHHHHHHEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCHH
NLAEVVRAGCDWIVTGSAIFHSPDPEATMREMREIAAHATAVQC
HHHHHHHCCCCEEEECCEEEECCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]