Click here to switch to the map view.

The map label for this gene is ttcA [H]

Identifier: 116622294

GI number: 116622294

Start: 4036918

End: 4037700

Strand: Reverse

Name: ttcA [H]

Synonym: Acid_3188

Alternate gene names: 116622294

Gene position: 4037700-4036918 (Counterclockwise)

Preceding gene: 116622305

Following gene: 116622293

Centisome position: 40.52

GC content: 60.66

Gene sequence:

>783_bases
GTGGACCTGGAAAAAACGCTGCTGCACAAGGTAGGGGAAGCGATTCACCGCTTCAAGATGATTCGCGATGGCGACCGCGT
GGCTGTGGCACTCTCCGGCGGTAAGGACTCTGCCACCATGCTCGAAGCCCTCCTGCTGCTGCAGAAGCGCGCGCCCATCG
ATTTCTCGGTGGTCTCCTTCACCGTCGAGCAGGGGAAATTCCTCCGCCCGATCGAACCCGTCGGGGAGTATCTGAAACAG
CGCGGAATTCCCTGGACTTACTTCCGCGATGACCCTTCCATGCGCCTGCTCGAAGAACAGCCCGACCACGGCTGCGATTT
GTGCAGCCGCTACCGCCGCCGCGCCGTCTACGAAATCGCCCGCGACCTGGGTGTCAATGTCATCGCCTTCGGCCACACCG
CCGATGATTTCTGCGAAGCCCTGTTACGCAACACCATGTTCACCGGAAAGCTCAGTTCCCTGCCCCCGGTCACCTGGTCG
CGCAATCGCGATTACCGCCTCATCCGGCCCCTGTGCTTCGTCACCGAAGACATCACCACGGCCTACGCCGCGTCAATGGG
TATCCCCGTCATTCCCTGCGGCTGCTCGCAGCGTACCGGTACGGTGCGGCGCGCGCTCCGCGACCTGTTCGCCGGGTTGG
AGCAGGAACATCCTCATCTCAAAGAAAACATGCTTTCCGCCATGGGTAACGTGGATACTTCCCGCCTCCTGGACACCCGC
TTTCTCAACGACGCCCCGGAAACAAAAACCGAGGAATTGTTCCCGATTGTCACCGAAATGTAA

Upstream 100 bases:

>100_bases
CTTCCGCCATTTGCCTTAGTTAATCCGTTGATCTTCTCCGCGCTACTCTGCGGGTCTCCGTGAAATTGGAAATTTCCGCA
ATAGTGCCATAATTGATCCA

Downstream 100 bases:

>100_bases
TTCTGGGTCGATTGACCCTGGGCCTGCATACCGATTACCATGAGTCTCTCGAAATCCAAGCCCAACTTATGAGATTGCTT
CCACGCGAGGAGAAGTTTTA

Product: PP-loop domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MDLEKTLLHKVGEAIHRFKMIRDGDRVAVALSGGKDSATMLEALLLLQKRAPIDFSVVSFTVEQGKFLRPIEPVGEYLKQ
RGIPWTYFRDDPSMRLLEEQPDHGCDLCSRYRRRAVYEIARDLGVNVIAFGHTADDFCEALLRNTMFTGKLSSLPPVTWS
RNRDYRLIRPLCFVTEDITTAYAASMGIPVIPCGCSQRTGTVRRALRDLFAGLEQEHPHLKENMLSAMGNVDTSRLLDTR
FLNDAPETKTEELFPIVTEM

Sequences:

>Translated_260_residues
MDLEKTLLHKVGEAIHRFKMIRDGDRVAVALSGGKDSATMLEALLLLQKRAPIDFSVVSFTVEQGKFLRPIEPVGEYLKQ
RGIPWTYFRDDPSMRLLEEQPDHGCDLCSRYRRRAVYEIARDLGVNVIAFGHTADDFCEALLRNTMFTGKLSSLPPVTWS
RNRDYRLIRPLCFVTEDITTAYAASMGIPVIPCGCSQRTGTVRRALRDLFAGLEQEHPHLKENMLSAMGNVDTSRLLDTR
FLNDAPETKTEELFPIVTEM
>Mature_260_residues
MDLEKTLLHKVGEAIHRFKMIRDGDRVAVALSGGKDSATMLEALLLLQKRAPIDFSVVSFTVEQGKFLRPIEPVGEYLKQ
RGIPWTYFRDDPSMRLLEEQPDHGCDLCSRYRRRAVYEIARDLGVNVIAFGHTADDFCEALLRNTMFTGKLSSLPPVTWS
RNRDYRLIRPLCFVTEDITTAYAASMGIPVIPCGCSQRTGTVRRALRDLFAGLEQEHPHLKENMLSAMGNVDTSRLLDTR
FLNDAPETKTEELFPIVTEM

Specific function: Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) [H]

COG id: COG0037

COG function: function code D; Predicted ATPase of the PP-loop superfamily implicated in cell cycle control

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TtcA family [H]

Homologues:

Organism=Escherichia coli, GI1787606, Length=244, Percent_Identity=37.7049180327869, Blast_Score=165, Evalue=4e-42,
Organism=Caenorhabditis elegans, GI193211090, Length=236, Percent_Identity=30.9322033898305, Blast_Score=101, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012089
- InterPro:   IPR014729
- InterPro:   IPR011063 [H]

Pfam domain/function: PF01171 ATP_bind_3 [H]

EC number: NA

Molecular weight: Translated: 29480; Mature: 29480

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLEKTLLHKVGEAIHRFKMIRDGDRVAVALSGGKDSATMLEALLLLQKRAPIDFSVVSF
CCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCCCCHHEEE
TVEQGKFLRPIEPVGEYLKQRGIPWTYFRDDPSMRLLEEQPDHGCDLCSRYRRRAVYEIA
ECCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHH
RDLGVNVIAFGHTADDFCEALLRNTMFTGKLSSLPPVTWSRNRDYRLIRPLCFVTEDITT
HHCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
AYAASMGIPVIPCGCSQRTGTVRRALRDLFAGLEQEHPHLKENMLSAMGNVDTSRLLDTR
HHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHH
FLNDAPETKTEELFPIVTEM
HHCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MDLEKTLLHKVGEAIHRFKMIRDGDRVAVALSGGKDSATMLEALLLLQKRAPIDFSVVSF
CCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCCCCHHEEE
TVEQGKFLRPIEPVGEYLKQRGIPWTYFRDDPSMRLLEEQPDHGCDLCSRYRRRAVYEIA
ECCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHH
RDLGVNVIAFGHTADDFCEALLRNTMFTGKLSSLPPVTWSRNRDYRLIRPLCFVTEDITT
HHCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
AYAASMGIPVIPCGCSQRTGTVRRALRDLFAGLEQEHPHLKENMLSAMGNVDTSRLLDTR
HHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHH
FLNDAPETKTEELFPIVTEM
HHCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA