Click here to switch to the map view.

The map label for this gene is udk [H]

Identifier: 116622288

GI number: 116622288

Start: 4032070

End: 4032693

Strand: Direct

Name: udk [H]

Synonym: Acid_3182

Alternate gene names: 116622288

Gene position: 4032070-4032693 (Clockwise)

Preceding gene: 116622287

Following gene: 116622289

Centisome position: 40.46

GC content: 62.5

Gene sequence:

>624_bases
ATGAGTGCACACATTATTGGTGTAGCGGGTCCGTCCAGCTCCGGGAAATCCGAGCTGGCGCGGCAACTGGCAGAGAGATT
GCCCGGGACCTCCATCGTTTCCCTGGATTCGTACTACCGAGGAATGGAAGAGATCCCGCTCGAGGAGCGGAAGAAGGTCA
ATTTCGACCATCCCGATTCCCTGGACTGGGAGTTGTTGCACGAGCACCTTGTGGCGATCGCCGCCGGTCGCGCGTTCGAC
GAACCGGTTTACAGTTTCGCGGATTATGAGCGAACCACGGAGACGCGGCGCATCGAACCGACGGAGTTCCTGATTGTGGA
GGGCCTCTTCGTGCTCTACTGGCCCGAGCTTCGCAAGATGCTGGACACCAAAGTCTACGTGCAGACGGATTCCGCGGTCT
GTTTTCAGCGGCGGTTGTCGCGCGATGTAGCGGAGCGCGGGCGCACTCCGGAGAGCGTGCGCGAGCAGTACGAGCGCACG
GTACGGCCGAGCGCGGAGTGGTTCGTGTACCCGACGGAGAAGTACGCCGATTTGCGGGTAAGCGGTGAAGAGCCGTTCGA
GCGTTCGACGGCGGCGGTGCTGAAGGCGCTGCACCGGGCCAAAGCGGCGGCGGGCGGAGCGTAA

Upstream 100 bases:

>100_bases
TCGGAGTGGCGGTAACGGTGGAAGCGCGGCCATTTACGGTGGATGGACTTGTCGATGCAGTGCTCGAGTTGTACACTGAA
ATGACTCCCCCGTCAACTGA

Downstream 100 bases:

>100_bases
AGCCGCGCTACCATTGTTCTCATGCTGACTCGTGAACAGGCGTGGGAAATCGTCTGCGAATTTACCAAATCCGAGGGCTT
GCGCAAGCATGCGCTGGCGG

Product: uridine kinase

Products: NA

Alternate protein names: Cytidine monophosphokinase; Uridine monophosphokinase [H]

Number of amino acids: Translated: 207; Mature: 206

Protein sequence:

>207_residues
MSAHIIGVAGPSSSGKSELARQLAERLPGTSIVSLDSYYRGMEEIPLEERKKVNFDHPDSLDWELLHEHLVAIAAGRAFD
EPVYSFADYERTTETRRIEPTEFLIVEGLFVLYWPELRKMLDTKVYVQTDSAVCFQRRLSRDVAERGRTPESVREQYERT
VRPSAEWFVYPTEKYADLRVSGEEPFERSTAAVLKALHRAKAAAGGA

Sequences:

>Translated_207_residues
MSAHIIGVAGPSSSGKSELARQLAERLPGTSIVSLDSYYRGMEEIPLEERKKVNFDHPDSLDWELLHEHLVAIAAGRAFD
EPVYSFADYERTTETRRIEPTEFLIVEGLFVLYWPELRKMLDTKVYVQTDSAVCFQRRLSRDVAERGRTPESVREQYERT
VRPSAEWFVYPTEKYADLRVSGEEPFERSTAAVLKALHRAKAAAGGA
>Mature_206_residues
SAHIIGVAGPSSSGKSELARQLAERLPGTSIVSLDSYYRGMEEIPLEERKKVNFDHPDSLDWELLHEHLVAIAAGRAFDE
PVYSFADYERTTETRRIEPTEFLIVEGLFVLYWPELRKMLDTKVYVQTDSAVCFQRRLSRDVAERGRTPESVREQYERTV
RPSAEWFVYPTEKYADLRVSGEEPFERSTAAVLKALHRAKAAAGGA

Specific function: Pyrimidine salvage pathway. [C]

COG id: COG0572

COG function: function code F; Uridine kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uridine kinase family [H]

Homologues:

Organism=Homo sapiens, GI301129207, Length=182, Percent_Identity=35.7142857142857, Blast_Score=127, Evalue=9e-30,
Organism=Homo sapiens, GI57863312, Length=182, Percent_Identity=35.7142857142857, Blast_Score=126, Evalue=1e-29,
Organism=Homo sapiens, GI18699734, Length=187, Percent_Identity=35.2941176470588, Blast_Score=124, Evalue=4e-29,
Organism=Homo sapiens, GI13899253, Length=185, Percent_Identity=36.2162162162162, Blast_Score=120, Evalue=7e-28,
Organism=Homo sapiens, GI209863022, Length=181, Percent_Identity=32.0441988950276, Blast_Score=90, Evalue=1e-18,
Organism=Escherichia coli, GI87082034, Length=182, Percent_Identity=42.3076923076923, Blast_Score=154, Evalue=5e-39,
Organism=Caenorhabditis elegans, GI17539894, Length=180, Percent_Identity=36.1111111111111, Blast_Score=129, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17539892, Length=180, Percent_Identity=36.1111111111111, Blast_Score=129, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI71981181, Length=188, Percent_Identity=35.1063829787234, Blast_Score=110, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6324339, Length=155, Percent_Identity=34.1935483870968, Blast_Score=105, Evalue=5e-24,
Organism=Drosophila melanogaster, GI45550449, Length=180, Percent_Identity=36.6666666666667, Blast_Score=134, Evalue=6e-32,
Organism=Drosophila melanogaster, GI28573516, Length=180, Percent_Identity=36.6666666666667, Blast_Score=130, Evalue=4e-31,
Organism=Drosophila melanogaster, GI28573514, Length=180, Percent_Identity=36.6666666666667, Blast_Score=130, Evalue=4e-31,
Organism=Drosophila melanogaster, GI28573512, Length=180, Percent_Identity=36.6666666666667, Blast_Score=130, Evalue=4e-31,
Organism=Drosophila melanogaster, GI221458995, Length=196, Percent_Identity=35.2040816326531, Blast_Score=119, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24649624, Length=196, Percent_Identity=35.2040816326531, Blast_Score=119, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006083
- InterPro:   IPR000764 [H]

Pfam domain/function: PF00485 PRK [H]

EC number: =2.7.1.48 [H]

Molecular weight: Translated: 23540; Mature: 23409

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAHIIGVAGPSSSGKSELARQLAERLPGTSIVSLDSYYRGMEEIPLEERKKVNFDHPDS
CCCEEEEEECCCCCCHHHHHHHHHHHCCCCEEEEHHHHHCCHHHCCCHHHHCCCCCCCCC
LDWELLHEHLVAIAAGRAFDEPVYSFADYERTTETRRIEPTEFLIVEGLFVLYWPELRKM
CCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
LDTKVYVQTDSAVCFQRRLSRDVAERGRTPESVREQYERTVRPSAEWFVYPTEKYADLRV
HCCEEEEECCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCEEEE
SGEEPFERSTAAVLKALHRAKAAAGGA
CCCCCHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SAHIIGVAGPSSSGKSELARQLAERLPGTSIVSLDSYYRGMEEIPLEERKKVNFDHPDS
CCEEEEEECCCCCCHHHHHHHHHHHCCCCEEEEHHHHHCCHHHCCCHHHHCCCCCCCCC
LDWELLHEHLVAIAAGRAFDEPVYSFADYERTTETRRIEPTEFLIVEGLFVLYWPELRKM
CCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
LDTKVYVQTDSAVCFQRRLSRDVAERGRTPESVREQYERTVRPSAEWFVYPTEKYADLRV
HCCEEEEECCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCEEEE
SGEEPFERSTAAVLKALHRAKAAAGGA
CCCCCHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA