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The map label for this gene is yleA [C]

Identifier: 116622276

GI number: 116622276

Start: 4013325

End: 4014659

Strand: Reverse

Name: yleA [C]

Synonym: Acid_3170

Alternate gene names: 116622276

Gene position: 4014659-4013325 (Counterclockwise)

Preceding gene: 116622278

Following gene: 116622270

Centisome position: 40.29

GC content: 66.44

Gene sequence:

>1335_bases
GTGGGGAAATTCTTCGTTCAAAACTTCGGCTGCCGGGCCACTCAGGCCGATGGCGCAGCCCTGGAGTCGCTGCTCGCGGC
CAAGGGTCTGGAAGCCACCGGCGCGCGTGCCGGCGCCGATCTGGTGGTGCTCAACACCTGCACCGTGACGGCCTCCGCCG
ACGACGACGTGCGCCAGACCATCCGCCGCGTCCATCGCGAAAACCCCGCCGCGCGGATTCTCGTCACCGGCTGCTACGCG
CAGCGCGCGCCCGAAGAACTCATCGCCCTCCCCGGCGTCGAATGGGTGGTCGGCAATTCCCACAAGACTCAGATCGCCGA
GATCGTGACCGCCGCGCCCGTCACCGAAGCGTTCTATCACGGCAACATTCACATCGGCGACATCTTCGCGCAGCATGATT
TTCTCTCCGCGCCGGTCGAAGACGCCGCCGGAGATCGCACGCGTCCGAACCTCAAAATTCAAGACGGCTGCAACAATCGC
TGCTCCTTCTGCATAATCCCGTTTGTCCGCGGACGCAGCCGAAGCGCTCCCGCCGCGCAGGTGGTGGAACAGGTGCGCGC
GCTTGCCGCCCGCTATCACGAGGTCGTCCTCAGCGGAATCAATCTGGGACGCTGGGGCCGCGAACCCGGCAGCAGCATGC
GGCTCGCCGGCCTTTTGCGGCTGCTGCTGGCCGAGACCGACGTCGCGCGGCTGCGGCTGAGTTCGGTCGAGCCGATGGAT
TTCTCCGAAGACCTGCTGCATCTGATGGCCGCCTCCCCGCGCATCGCCAATCACGTCCACGCGCCCCTGCAAAGCGGCAG
CGACCGCGTGCTCCGCCGCATGCACCGCAAGTATCGCCCGCGCCATTACGCCGACCGCGTGCTGAAGGCGCGCGCACTCA
TGCCCGACGGCGCCATCGGCGCCGACGTCATGGTCGGTTTTCCCGGGGAAACCGACGCGGAGTTTGAAGAGAGCCGCCGC
TTCATCGAGCAGCTGCCCTTCACTTACCTGCACGTCTTCACCTACTCGGAAAGGCCGGGTACGCCGGCGGCGGAAAGTGA
GCACCCGGTGCCGATGCCAGTTCGAAAGGAGCGGAACCGGGTGCTGCGGGAACTCGCCGCCGCCAAAAATCTTGCATTCC
GCGAGAGCATGATCGGTCGCACGTTATCGGCTGTCACGCTCGCGGAGACGGGAATCGCGCTGACGGAAAATTACCTGAAA
GTGGAACTGGCCTCCCCGCGCGAGCCCGGAGCGCTGGTGGATTTGCACATCGGCGGGCTCGCCTCCGCGGGGCTGCGCGA
GCAGGCGCTCTGCCAGGTGCTGCCCGCGCTGTCCGTCTCTACGCAGCGTCTCTGA

Upstream 100 bases:

>100_bases
GATGCTCCTGGTCCACCATAATACTCTCCATCACGTCCACCGGCACTCCCCAGCCCACGGAGCGATCGGGAGTATTTTCG
ATCTCCTATACTAATTAAAG

Downstream 100 bases:

>100_bases
GCACTGCGGACGCCACCGGCGATCCGGGAATTCCGGCGTTGAACGCGAGCTGCACCGGCACTTCACGGAGATGCATCGGA
TCAATGCCGCGGGCAGGTTG

Product: MiaB-like tRNA modifying protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 444; Mature: 443

Protein sequence:

>444_residues
MGKFFVQNFGCRATQADGAALESLLAAKGLEATGARAGADLVVLNTCTVTASADDDVRQTIRRVHRENPAARILVTGCYA
QRAPEELIALPGVEWVVGNSHKTQIAEIVTAAPVTEAFYHGNIHIGDIFAQHDFLSAPVEDAAGDRTRPNLKIQDGCNNR
CSFCIIPFVRGRSRSAPAAQVVEQVRALAARYHEVVLSGINLGRWGREPGSSMRLAGLLRLLLAETDVARLRLSSVEPMD
FSEDLLHLMAASPRIANHVHAPLQSGSDRVLRRMHRKYRPRHYADRVLKARALMPDGAIGADVMVGFPGETDAEFEESRR
FIEQLPFTYLHVFTYSERPGTPAAESEHPVPMPVRKERNRVLRELAAAKNLAFRESMIGRTLSAVTLAETGIALTENYLK
VELASPREPGALVDLHIGGLASAGLREQALCQVLPALSVSTQRL

Sequences:

>Translated_444_residues
MGKFFVQNFGCRATQADGAALESLLAAKGLEATGARAGADLVVLNTCTVTASADDDVRQTIRRVHRENPAARILVTGCYA
QRAPEELIALPGVEWVVGNSHKTQIAEIVTAAPVTEAFYHGNIHIGDIFAQHDFLSAPVEDAAGDRTRPNLKIQDGCNNR
CSFCIIPFVRGRSRSAPAAQVVEQVRALAARYHEVVLSGINLGRWGREPGSSMRLAGLLRLLLAETDVARLRLSSVEPMD
FSEDLLHLMAASPRIANHVHAPLQSGSDRVLRRMHRKYRPRHYADRVLKARALMPDGAIGADVMVGFPGETDAEFEESRR
FIEQLPFTYLHVFTYSERPGTPAAESEHPVPMPVRKERNRVLRELAAAKNLAFRESMIGRTLSAVTLAETGIALTENYLK
VELASPREPGALVDLHIGGLASAGLREQALCQVLPALSVSTQRL
>Mature_443_residues
GKFFVQNFGCRATQADGAALESLLAAKGLEATGARAGADLVVLNTCTVTASADDDVRQTIRRVHRENPAARILVTGCYAQ
RAPEELIALPGVEWVVGNSHKTQIAEIVTAAPVTEAFYHGNIHIGDIFAQHDFLSAPVEDAAGDRTRPNLKIQDGCNNRC
SFCIIPFVRGRSRSAPAAQVVEQVRALAARYHEVVLSGINLGRWGREPGSSMRLAGLLRLLLAETDVARLRLSSVEPMDF
SEDLLHLMAASPRIANHVHAPLQSGSDRVLRRMHRKYRPRHYADRVLKARALMPDGAIGADVMVGFPGETDAEFEESRRF
IEQLPFTYLHVFTYSERPGTPAAESEHPVPMPVRKERNRVLRELAAAKNLAFRESMIGRTLSAVTLAETGIALTENYLKV
ELASPREPGALVDLHIGGLASAGLREQALCQVLPALSVSTQRL

Specific function: Unknown

COG id: COG0621

COG function: function code J; 2-methylthioadenine synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MTTase N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI93277076, Length=366, Percent_Identity=29.7814207650273, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI28872784, Length=405, Percent_Identity=26.1728395061728, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI28872782, Length=483, Percent_Identity=25.2587991718427, Blast_Score=137, Evalue=3e-32,
Organism=Escherichia coli, GI1786882, Length=444, Percent_Identity=29.954954954955, Blast_Score=192, Evalue=4e-50,
Organism=Escherichia coli, GI1787057, Length=390, Percent_Identity=25.8974358974359, Blast_Score=111, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17553146, Length=402, Percent_Identity=26.865671641791, Blast_Score=142, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI71996771, Length=203, Percent_Identity=35.4679802955665, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI21356207, Length=392, Percent_Identity=28.5714285714286, Blast_Score=155, Evalue=6e-38,
Organism=Drosophila melanogaster, GI19922432, Length=373, Percent_Identity=30.0268096514745, Blast_Score=137, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR005839
- InterPro:   IPR020612
- InterPro:   IPR013848
- InterPro:   IPR006467
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM; PF00919 UPF0004 [H]

EC number: NA

Molecular weight: Translated: 48481; Mature: 48350

Theoretical pI: Translated: 8.10; Mature: 8.10

Prosite motif: PS01278 UPF0004

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKFFVQNFGCRATQADGAALESLLAAKGLEATGARAGADLVVLNTCTVTASADDDVRQT
CCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEEEECCCHHHHHH
IRRVHRENPAARILVTGCYAQRAPEELIALPGVEWVVGNSHKTQIAEIVTAAPVTEAFYH
HHHHHCCCCCEEEEEEEHHHHHCCHHHHCCCCCEEEECCCCHHHHHHHHHHCHHHHHHHC
GNIHIGDIFAQHDFLSAPVEDAAGDRTRPNLKIQDGCNNRCSFCIIPFVRGRSRSAPAAQ
CCEEEEHHHHHCCHHCCCHHHCCCCCCCCCEEECCCCCCCCCEEEEECCCCCCCCCCHHH
VVEQVRALAARYHEVVLSGINLGRWGREPGSSMRLAGLLRLLLAETDVARLRLSSVEPMD
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHCCCCCCC
FSEDLLHLMAASPRIANHVHAPLQSGSDRVLRRMHRKYRPRHYADRVLKARALMPDGAIG
HHHHHHHHHHCCCHHHHHHHCHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCC
ADVMVGFPGETDAEFEESRRFIEQLPFTYLHVFTYSERPGTPAAESEHPVPMPVRKERNR
CCEEEECCCCCCCHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHH
VLRELAAAKNLAFRESMIGRTLSAVTLAETGIALTENYLKVELASPREPGALVDLHIGGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEECCEEEEEECCCCCCCCEEEEEECCC
ASAGLREQALCQVLPALSVSTQRL
CCCCHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
GKFFVQNFGCRATQADGAALESLLAAKGLEATGARAGADLVVLNTCTVTASADDDVRQT
CCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEEEECCCHHHHHH
IRRVHRENPAARILVTGCYAQRAPEELIALPGVEWVVGNSHKTQIAEIVTAAPVTEAFYH
HHHHHCCCCCEEEEEEEHHHHHCCHHHHCCCCCEEEECCCCHHHHHHHHHHCHHHHHHHC
GNIHIGDIFAQHDFLSAPVEDAAGDRTRPNLKIQDGCNNRCSFCIIPFVRGRSRSAPAAQ
CCEEEEHHHHHCCHHCCCHHHCCCCCCCCCEEECCCCCCCCCEEEEECCCCCCCCCCHHH
VVEQVRALAARYHEVVLSGINLGRWGREPGSSMRLAGLLRLLLAETDVARLRLSSVEPMD
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHCCCCCCC
FSEDLLHLMAASPRIANHVHAPLQSGSDRVLRRMHRKYRPRHYADRVLKARALMPDGAIG
HHHHHHHHHHCCCHHHHHHHCHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCC
ADVMVGFPGETDAEFEESRRFIEQLPFTYLHVFTYSERPGTPAAESEHPVPMPVRKERNR
CCEEEECCCCCCCHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHH
VLRELAAAKNLAFRESMIGRTLSAVTLAETGIALTENYLKVELASPREPGALVDLHIGGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEECCEEEEEECCCCCCCCEEEEEECCC
ASAGLREQALCQVLPALSVSTQRL
CCCCHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]