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The map label for this gene is 116622267

Identifier: 116622267

GI number: 116622267

Start: 4004473

End: 4005714

Strand: Reverse

Name: 116622267

Synonym: Acid_3161

Alternate gene names: NA

Gene position: 4005714-4004473 (Counterclockwise)

Preceding gene: 116622268

Following gene: 116622260

Centisome position: 40.2

GC content: 64.65

Gene sequence:

>1242_bases
ATGAGGATTCTGATCGCCTGTGGAATCGCGGTGTGCGCCGCGGCGCAGACCATCGACGTGACGCCACCGAAAGTGATGAT
GGACGAGGCTGTCGCGGTGAAGGTCAGCGGCCTCGCGGCGAATGAGCATGCGACCATTCGCGCCGAGCTGACTGATGGCG
GCGGGCAGCAGTGGGCGTCCCAGGCAGAGTATGCCGCGGATGAAAACGGCGTGATCGACGTGTTGCGGCGAGCGCCGGTC
GCAGGCTCCTACAAGGAGCTGTCGCCGATGGGACTGGTGTGGTCGATGATGCCGGCATCCAAACACGTATCGACATACCA
GCCGCCGCGCGATCTCGGGCCGCAGACCATCGAGTTCACCTTGATGCGGAAGAATGAAAAGCTCGCGAAAGCGCGACTGG
AGCAGACTACGCTGGCGGAAGGTGTGCGCCGAAGGGTCGTGCGCGAGGGACCGCTGCGTGGCGTGATCTTCGCGCCACCG
GGAGAGGGGCGGCACCCGGGCGTGCTGGTGGTGGGCGGATCAAATGGCGGATTGCCGGCGAAGCAGGCGGCGTGGCTCGC
GGCACACGGATTCGCGGCGCTGGCGCTGGCCTATTTCCGCTACGAGGATCTGCCGCAGCAACTCGAAGATATTCCGCTGG
AGTACTTCGGGCGCGCGCTGGAATGGATGGCGCAGCAGAAGGAGATCGCGCCGGACCATCTGGCGGTGATGGGAACTTCG
CGCGGCGGAGAGCTGGCGCTGCAATTGGGGTCAATGTTCCCGAGTATTCGGGCGGTGGTGGCCTATGTGCCGGCAGATGT
GCGTTACGCATCGTGCTGTCTTATGAAGGGCACGGCGGCATGGACGTGGCAGGGCCAGGCGCTGCCGTATCTCGCGCCGC
GATTCGGCCGGCCGCCGGAGTTGGTAGCGCGGGCCGCCATCGAAGCGGAGCGGACCCACGGGCCGATTCTGATGATCTCG
GGCGAGGACGATCACTTGTGGCGATCGTGGGAGATGGCGGATAACGTGGTGGCCCGACTCAAGCGAGCTCACTTTCCGTA
CCGCTTCGAGAATTTGAAGTATCCGCATGCGGGGCACTCGGCGGGCAGGCCAGGGATTCAACCGGCTTGGCACGGGGCCG
TGCACAATCCCACGTCGGTCCGGGAGAATGATCTGGGCGGCTCGGCCAAGGGAGATGCGCAGTCCACCCTTGACTCCATG
CCGAAGGTGATTGAGTTTCTGACCGCGAGTACACGCGAATGA

Upstream 100 bases:

>100_bases
AGAAACCTCTGCCTGGGACCAGCGGTCCGTCCGGCCACGGTCCAAACGGCCGTGCCGGAACGGCAGGCGCCATCGAATCG
GTGAAAGGGATGGAGTTGCC

Downstream 100 bases:

>100_bases
TTCGAAACTTCCGGAAGCCCTCGTTCTGGCAGTCCCTGGTGGCCGTGTTGGCGGGAAATGCCATTTACCTGGGTGTGGAG
CGGTTCCTGCCAGTACGCGC

Product: palmitoyl-CoA hydrolase

Products: NA

Alternate protein names: Palmitoyl-CoA Hydrolase; BAAT/Acyl-CoA Thioester Hydrolase; Acyl-CoA Thioesterase; Dienelactone Hydrolase Family Protein; Bile Acid-CoAAmino Acid N-Acyltransferase; BAAT/Acyl-CoA Thioester Hydrolase Family; Thioesterase; Dienelactone Hydrolase-Like; BAAT/Acyl-CoA Thioester Hydrolase-Like Protein; Acyl CoA Thioesterase; Alpha/Beta Fold Family Hydrolase; Acyl Co A Thioester Hydrolase Protein; Acyl-CoA Thioesterase 1 Truncated; Long-Chain Fatty-Acyl-CoA Hydrolase

Number of amino acids: Translated: 413; Mature: 413

Protein sequence:

>413_residues
MRILIACGIAVCAAAQTIDVTPPKVMMDEAVAVKVSGLAANEHATIRAELTDGGGQQWASQAEYAADENGVIDVLRRAPV
AGSYKELSPMGLVWSMMPASKHVSTYQPPRDLGPQTIEFTLMRKNEKLAKARLEQTTLAEGVRRRVVREGPLRGVIFAPP
GEGRHPGVLVVGGSNGGLPAKQAAWLAAHGFAALALAYFRYEDLPQQLEDIPLEYFGRALEWMAQQKEIAPDHLAVMGTS
RGGELALQLGSMFPSIRAVVAYVPADVRYASCCLMKGTAAWTWQGQALPYLAPRFGRPPELVARAAIEAERTHGPILMIS
GEDDHLWRSWEMADNVVARLKRAHFPYRFENLKYPHAGHSAGRPGIQPAWHGAVHNPTSVRENDLGGSAKGDAQSTLDSM
PKVIEFLTASTRE

Sequences:

>Translated_413_residues
MRILIACGIAVCAAAQTIDVTPPKVMMDEAVAVKVSGLAANEHATIRAELTDGGGQQWASQAEYAADENGVIDVLRRAPV
AGSYKELSPMGLVWSMMPASKHVSTYQPPRDLGPQTIEFTLMRKNEKLAKARLEQTTLAEGVRRRVVREGPLRGVIFAPP
GEGRHPGVLVVGGSNGGLPAKQAAWLAAHGFAALALAYFRYEDLPQQLEDIPLEYFGRALEWMAQQKEIAPDHLAVMGTS
RGGELALQLGSMFPSIRAVVAYVPADVRYASCCLMKGTAAWTWQGQALPYLAPRFGRPPELVARAAIEAERTHGPILMIS
GEDDHLWRSWEMADNVVARLKRAHFPYRFENLKYPHAGHSAGRPGIQPAWHGAVHNPTSVRENDLGGSAKGDAQSTLDSM
PKVIEFLTASTRE
>Mature_413_residues
MRILIACGIAVCAAAQTIDVTPPKVMMDEAVAVKVSGLAANEHATIRAELTDGGGQQWASQAEYAADENGVIDVLRRAPV
AGSYKELSPMGLVWSMMPASKHVSTYQPPRDLGPQTIEFTLMRKNEKLAKARLEQTTLAEGVRRRVVREGPLRGVIFAPP
GEGRHPGVLVVGGSNGGLPAKQAAWLAAHGFAALALAYFRYEDLPQQLEDIPLEYFGRALEWMAQQKEIAPDHLAVMGTS
RGGELALQLGSMFPSIRAVVAYVPADVRYASCCLMKGTAAWTWQGQALPYLAPRFGRPPELVARAAIEAERTHGPILMIS
GEDDHLWRSWEMADNVVARLKRAHFPYRFENLKYPHAGHSAGRPGIQPAWHGAVHNPTSVRENDLGGSAKGDAQSTLDSM
PKVIEFLTASTRE

Specific function: Unknown

COG id: COG1073

COG function: function code R; Hydrolases of the alpha/beta superfamily

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI81230485, Length=402, Percent_Identity=31.8407960199005, Blast_Score=172, Evalue=4e-43,
Organism=Homo sapiens, GI148727286, Length=407, Percent_Identity=31.2039312039312, Blast_Score=172, Evalue=7e-43,
Organism=Homo sapiens, GI187761341, Length=417, Percent_Identity=29.9760191846523, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI189083866, Length=367, Percent_Identity=31.3351498637602, Blast_Score=142, Evalue=8e-34,
Organism=Homo sapiens, GI4502351, Length=367, Percent_Identity=31.3351498637602, Blast_Score=142, Evalue=8e-34,
Organism=Caenorhabditis elegans, GI212632908, Length=248, Percent_Identity=28.2258064516129, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17508861, Length=263, Percent_Identity=29.6577946768061, Blast_Score=111, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI71993180, Length=248, Percent_Identity=28.6290322580645, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI71992104, Length=245, Percent_Identity=29.3877551020408, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI212632910, Length=176, Percent_Identity=29.5454545454545, Blast_Score=88, Evalue=9e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 44868; Mature: 44868

Theoretical pI: Translated: 7.70; Mature: 7.70

Prosite motif: PS00678 WD_REPEATS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILIACGIAVCAAAQTIDVTPPKVMMDEAVAVKVSGLAANEHATIRAELTDGGGQQWAS
CEEEEEEHHHHHHCCCEECCCCCHHHHCCEEEEEEECEECCCCEEEEEEECCCCCHHHHH
QAEYAADENGVIDVLRRAPVAGSYKELSPMGLVWSMMPASKHVSTYQPPRDLGPQTIEFT
HHHHCCCCCCHHHHHHCCCCCCCHHHCCCHHHHEECCCCCCCCCCCCCCHHCCCCEEEEE
LMRKNEKLAKARLEQTTLAEGVRRRVVREGPLRGVIFAPPGEGRHPGVLVVGGSNGGLPA
EEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCEEEEECCCCCCCH
KQAAWLAAHGFAALALAYFRYEDLPQQLEDIPLEYFGRALEWMAQQKEIAPDHLAVMGTS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEEEECC
RGGELALQLGSMFPSIRAVVAYVPADVRYASCCLMKGTAAWTWQGQALPYLAPRFGRPPE
CCCCEEEEHHHHCHHHHHHHHHCCCCCHHHHEEEECCCEEEEECCCCCCCCCCCCCCCHH
LVARAAIEAERTHGPILMISGEDDHLWRSWEMADNVVARLKRAHFPYRFENLKYPHAGHS
HHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCC
AGRPGIQPAWHGAVHNPTSVRENDLGGSAKGDAQSTLDSMPKVIEFLTASTRE
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRILIACGIAVCAAAQTIDVTPPKVMMDEAVAVKVSGLAANEHATIRAELTDGGGQQWAS
CEEEEEEHHHHHHCCCEECCCCCHHHHCCEEEEEEECEECCCCEEEEEEECCCCCHHHHH
QAEYAADENGVIDVLRRAPVAGSYKELSPMGLVWSMMPASKHVSTYQPPRDLGPQTIEFT
HHHHCCCCCCHHHHHHCCCCCCCHHHCCCHHHHEECCCCCCCCCCCCCCHHCCCCEEEEE
LMRKNEKLAKARLEQTTLAEGVRRRVVREGPLRGVIFAPPGEGRHPGVLVVGGSNGGLPA
EEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCEEEEECCCCCCCH
KQAAWLAAHGFAALALAYFRYEDLPQQLEDIPLEYFGRALEWMAQQKEIAPDHLAVMGTS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEEEECC
RGGELALQLGSMFPSIRAVVAYVPADVRYASCCLMKGTAAWTWQGQALPYLAPRFGRPPE
CCCCEEEEHHHHCHHHHHHHHHCCCCCHHHHEEEECCCEEEEECCCCCCCCCCCCCCCHH
LVARAAIEAERTHGPILMISGEDDHLWRSWEMADNVVARLKRAHFPYRFENLKYPHAGHS
HHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCC
AGRPGIQPAWHGAVHNPTSVRENDLGGSAKGDAQSTLDSMPKVIEFLTASTRE
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA