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The map label for this gene is 116622242

Identifier: 116622242

GI number: 116622242

Start: 3976118

End: 3977404

Strand: Direct

Name: 116622242

Synonym: Acid_3135

Alternate gene names: NA

Gene position: 3976118-3977404 (Clockwise)

Preceding gene: 116622241

Following gene: 116622243

Centisome position: 39.9

GC content: 62.86

Gene sequence:

>1287_bases
ATGAAGCGGCGGGTCCTCCTGCTGGTACTCTTGTGTGCCCTGGCGGTGCCGGCGGAAGCGGCGATCCGGCTGATCGTCAG
GGTTCAAGGCGGCGCGCCGGTTCTGCAGGCGGCGTGCCTGCTGCTCGGCTGCGATGTCCAGTACCCGTTGGGCGACGACG
AAGGGCAACTCGTGCTGGTGACGGTGCCGCTCAATCTTACGGCGAACCTTTTGCTGAACGTGCCGGGGGTCCTGAGGGTC
GAGGTAGATACAGTTGGACAAACTTCAGGCGCGACCCAGTCCGGGGCTCCCGCCGCGTTGTATGATGCGACCCCGGTGAG
TTACTTCGGAACCACGGTGCGCGAGGGCTATGTCAAGCAGCCCGCCGCGCAGATCATCGGACTCGCTGCGACGCAGAACA
GGTTTGGCGTGCGGGGGGCCGGGATTGTCGCGGTGATCGATACGGGCGTGGACTCGAGCCATCCCGCGCTCGCGGGCTCA
CTCGTGCCGGGATATGACTTCACGAGGAATCGGGCAGGCGCGGATGAGAAAGGAGACGTAGGGCAATCGACCACGGCGGT
GATCGATCAATCGACGACCGCGGTGGTGGACCAATCTACAACCGCGGTGATCGACCAGTACAGCGCCGCCGCGCTGAATC
AGCCGCAGTACCAGGCCTTCGGCCATGGCACCATGGTCTCTGGCGTGGTTCACCTGGTAGCTCCGGGAGCGATGATCATG
CCGTTGAAGGCTTTCCACGCCGATGGAACCGGATACGCGTCCGATGTAATTCGGGCGGTATATTTCGCGGTACACCATCG
CGCGCGGATTCTAAATATGAGTTTCAGCTTCCAATCCTCTCCCATGGAGCTGCAGTTAGCACTGACTTACGCCAAGTTAA
ACGGAGTTATCAGCGTGGCGGCCGCAGGCAACGAAGGACGCGAGACCATGGTGTACCCGGCAGGCTATTCGGGAACCGTG
ATGGGAGTGGCGTCCACGTCCAATTCGGACACCCTGTCCACCTTCTCTAACTACGGGCAGCGCCTGGTGTGGGTGGGCGC
ACCCGGCGAGGGAATTGTCACTCTGTATCCCTATGGAACGTACGCGGCAACCTGGGGTACGTCTTTCAGCGCACCGTTTG
CGGCCGGAGCGGCGGCGCTGCTGCTCGACGTTCAGGCGATGTGCGGTGAGCCGCAGGCGGCGGATTCACTCTCGCACGCG
AGGTACATCAACCCCGACCTGGGATATGGACGGCTGGACTTGTATCAGGCCGTGCAAGCGTGGCGCCGGGCGGCGGGACT
TCAGTAA

Upstream 100 bases:

>100_bases
ATCTGACATTTGCGCCGGCGGACAACCTTATGCTCACCGTGAGTCTGGAAGGGGAGTGCGTCCTGGTATCGGTTTTGCCT
CGTTCCAACGGTGAAGGCTC

Downstream 100 bases:

>100_bases
TCGGGATATATTTTTCCGAGGCCTTCCTGATCTTGATCATCGTGAGTTCGTGGACTTCATCGCGAGCTTTCAACCAGTAA
CGGTACGGCATATCTGGGAC

Product: fervidolysin

Products: NA

Alternate protein names: Ak.1 protease [H]

Number of amino acids: Translated: 428; Mature: 428

Protein sequence:

>428_residues
MKRRVLLLVLLCALAVPAEAAIRLIVRVQGGAPVLQAACLLLGCDVQYPLGDDEGQLVLVTVPLNLTANLLLNVPGVLRV
EVDTVGQTSGATQSGAPAALYDATPVSYFGTTVREGYVKQPAAQIIGLAATQNRFGVRGAGIVAVIDTGVDSSHPALAGS
LVPGYDFTRNRAGADEKGDVGQSTTAVIDQSTTAVVDQSTTAVIDQYSAAALNQPQYQAFGHGTMVSGVVHLVAPGAMIM
PLKAFHADGTGYASDVIRAVYFAVHHRARILNMSFSFQSSPMELQLALTYAKLNGVISVAAAGNEGRETMVYPAGYSGTV
MGVASTSNSDTLSTFSNYGQRLVWVGAPGEGIVTLYPYGTYAATWGTSFSAPFAAGAAALLLDVQAMCGEPQAADSLSHA
RYINPDLGYGRLDLYQAVQAWRRAAGLQ

Sequences:

>Translated_428_residues
MKRRVLLLVLLCALAVPAEAAIRLIVRVQGGAPVLQAACLLLGCDVQYPLGDDEGQLVLVTVPLNLTANLLLNVPGVLRV
EVDTVGQTSGATQSGAPAALYDATPVSYFGTTVREGYVKQPAAQIIGLAATQNRFGVRGAGIVAVIDTGVDSSHPALAGS
LVPGYDFTRNRAGADEKGDVGQSTTAVIDQSTTAVVDQSTTAVIDQYSAAALNQPQYQAFGHGTMVSGVVHLVAPGAMIM
PLKAFHADGTGYASDVIRAVYFAVHHRARILNMSFSFQSSPMELQLALTYAKLNGVISVAAAGNEGRETMVYPAGYSGTV
MGVASTSNSDTLSTFSNYGQRLVWVGAPGEGIVTLYPYGTYAATWGTSFSAPFAAGAAALLLDVQAMCGEPQAADSLSHA
RYINPDLGYGRLDLYQAVQAWRRAAGLQ
>Mature_428_residues
MKRRVLLLVLLCALAVPAEAAIRLIVRVQGGAPVLQAACLLLGCDVQYPLGDDEGQLVLVTVPLNLTANLLLNVPGVLRV
EVDTVGQTSGATQSGAPAALYDATPVSYFGTTVREGYVKQPAAQIIGLAATQNRFGVRGAGIVAVIDTGVDSSHPALAGS
LVPGYDFTRNRAGADEKGDVGQSTTAVIDQSTTAVVDQSTTAVIDQYSAAALNQPQYQAFGHGTMVSGVVHLVAPGAMIM
PLKAFHADGTGYASDVIRAVYFAVHHRARILNMSFSFQSSPMELQLALTYAKLNGVISVAAAGNEGRETMVYPAGYSGTV
MGVASTSNSDTLSTFSNYGQRLVWVGAPGEGIVTLYPYGTYAATWGTSFSAPFAAGAAALLLDVQAMCGEPQAADSLSHA
RYINPDLGYGRLDLYQAVQAWRRAAGLQ

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6319893, Length=254, Percent_Identity=27.1653543307087, Blast_Score=63, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500
- InterPro:   IPR009020 [H]

Pfam domain/function: PF00082 Peptidase_S8 [H]

EC number: NA

Molecular weight: Translated: 44620; Mature: 44620

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS00136 SUBTILASE_ASP ; PS00138 SUBTILASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRRVLLLVLLCALAVPAEAAIRLIVRVQGGAPVLQAACLLLGCDVQYPLGDDEGQLVLV
CCCHHHHHHHHHHHHCCHHHEEEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEE
TVPLNLTANLLLNVPGVLRVEVDTVGQTSGATQSGAPAALYDATPVSYFGTTVREGYVKQ
EECCCCEEEHEECCCCEEEEEEEECCCCCCCCCCCCCEEEECCCCHHHHHHHHHCCHHCC
PAAQIIGLAATQNRFGVRGAGIVAVIDTGVDSSHPALAGSLVPGYDFTRNRAGADEKGDV
CHHHHEEEEECCCCCCCCCCCEEEEEECCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCC
GQSTTAVIDQSTTAVVDQSTTAVIDQYSAAALNQPQYQAFGHGTMVSGVVHLVAPGAMIM
CCCCEEEEECCCEEEEECCHHHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHCCCCEEE
PLKAFHADGTGYASDVIRAVYFAVHHRARILNMSFSFQSSPMELQLALTYAKLNGVISVA
EEHEECCCCCCHHHHHHHHHHHHHHHHEEEEEEEEECCCCCCEEEEEEEEEECCCEEEEE
AAGNEGRETMVYPAGYSGTVMGVASTSNSDTLSTFSNYGQRLVWVGAPGEGIVTLYPYGT
ECCCCCCEEEEEECCCCCEEEEEEECCCCCHHHHHHHCCCEEEEEECCCCCEEEEEECCC
YAATWGTSFSAPFAAGAAALLLDVQAMCGEPQAADSLSHARYINPDLGYGRLDLYQAVQA
EEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHCCCCCEECCCCCCCCHHHHHHHHHH
WRRAAGLQ
HHHHHCCC
>Mature Secondary Structure
MKRRVLLLVLLCALAVPAEAAIRLIVRVQGGAPVLQAACLLLGCDVQYPLGDDEGQLVLV
CCCHHHHHHHHHHHHCCHHHEEEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEE
TVPLNLTANLLLNVPGVLRVEVDTVGQTSGATQSGAPAALYDATPVSYFGTTVREGYVKQ
EECCCCEEEHEECCCCEEEEEEEECCCCCCCCCCCCCEEEECCCCHHHHHHHHHCCHHCC
PAAQIIGLAATQNRFGVRGAGIVAVIDTGVDSSHPALAGSLVPGYDFTRNRAGADEKGDV
CHHHHEEEEECCCCCCCCCCCEEEEEECCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCC
GQSTTAVIDQSTTAVVDQSTTAVIDQYSAAALNQPQYQAFGHGTMVSGVVHLVAPGAMIM
CCCCEEEEECCCEEEEECCHHHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHCCCCEEE
PLKAFHADGTGYASDVIRAVYFAVHHRARILNMSFSFQSSPMELQLALTYAKLNGVISVA
EEHEECCCCCCHHHHHHHHHHHHHHHHEEEEEEEEECCCCCCEEEEEEEEEECCCEEEEE
AAGNEGRETMVYPAGYSGTVMGVASTSNSDTLSTFSNYGQRLVWVGAPGEGIVTLYPYGT
ECCCCCCEEEEEECCCCCEEEEEEECCCCCHHHHHHHCCCEEEEEECCCCCEEEEEECCC
YAATWGTSFSAPFAAGAAALLLDVQAMCGEPQAADSLSHARYINPDLGYGRLDLYQAVQA
EEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHCCCCCEECCCCCCCCHHHHHHHHHH
WRRAAGLQ
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7993087; 10588904 [H]