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The map label for this gene is qheDH [H]

Identifier: 116622229

GI number: 116622229

Start: 3957321

End: 3958877

Strand: Reverse

Name: qheDH [H]

Synonym: Acid_3122

Alternate gene names: 116622229

Gene position: 3958877-3957321 (Counterclockwise)

Preceding gene: 116622230

Following gene: 116622228

Centisome position: 39.73

GC content: 62.88

Gene sequence:

>1557_bases
GTGAAACGCAAGCTGTGGATCGCGGTATTTGCGCTCGCTGCTATCGGGGGAGCGGAAACGGGCTGGCAGATGTATGCCGG
CAACTACGCCGGATGGCGCTACAGCGAGCTCGCGCAGATCAATACCTCCAACGTCGCCGCGCTCGCACCCCGGTGGATCT
TCCAGACCCACGTGCCCGGTAATATGGAAACCACGCCGCTGGTGCAAAACGGGCTGATGTACCTGACGGCGCCTTCGAAC
CACGCCTTTGCGCTCGACCTGCGGACCGGCCACGCGATCTGGCACTACTCGCGGACTCCGCCCCACCCGCTGAACCTGTG
CTGCGGCGAAGTGAATCGCGGCTTCGCGGTTCTGGGCAACCGGCTTTTCAAAGTGACGATCGAAGACACGCTGCTCGCGC
TCGATATCGCGACCGGCAAGCCGCTCTGGGAGACCACGCTCGGCGATTACCGGAAGGGATACAGCGGCACGCTCGCGCCA
CTCGTGGTCAAGGACAAGGTCCTGGTGGGAACAGCCGGCGCCGAGTTCGGCATCCGCGGTTTTGTGGATGCCTATTCACC
GGAGACGGGCGAGCGCCTCTGGCGTTTCTACACGATCCCGTTGGCCGGTGAACCGGGCGGCGAAACATGGGGTAAGGAGT
CTAACTTGCGCGTCGGCGGCTCCACGTGGATTACGGGCACTTACGACCCCGAGTTAAATCTGACTTACTGGGGCACCGGC
AATCCCGGCCCCGACATGGACGGCGACGTACGGCCGGGAGACAACCTTTACACGTGCAGCTTGGTGGCGCTCGACGCGGA
CACCGGGAAGATGAAATGGCACTTCCAATTCACGCCCCACGACACGCACGATTGGGATGCCATCAGTGACCCCGTGCTGG
TGGATCTCGCGATTGAAGGGCGGAAAGTGAAGGCGGTGATCCAGGCCAACCGGAATGGGTACTTCTACGCGATCGACCGC
ACCAACGGGAAGTTCCTGTTCGCGCAGCCGTATACCAAGATCACGTGGGCCAGAGGCATCGGAGCGGATGGGCGGCCACA
AGTCATCCCGAACCTGGATCCGAGCCACGAGGGGACACGGGTCTGTCCCGGGCTGGGCGGCGGACATAACTGGCAGGCGA
CTGCGTACAGCCCGCTGGCGGGACTCTATTACTTCAGCAGCACGGATGGATGCCAGAATTTCTTCAAGAACGAGGGCGAG
TTCGTAGCCGGCGATTGGTACCAGCTGAGCGGCACGAAGGAAGTCCCGGGCGAGCAGCCGGCGGGTTCGTTCATCGCGAT
GGATCCCGCGACTGGAAAGGTGCGATGGCGCTTCGAAATGCTGCGCAATCCTTCCGGCGGAGCGCTGGCCACGGCCGGCG
GGCTGGTGTTCATCGGGGATAGCAATGGGAACCTGATCGGTTTCGACGCCAAGAGCGGCAAGGTGCTGTGGCGCTTCCAA
ACTGGAGCGCAGATTAGCGCGCCTCCGGTCAGCTACAGCTTCGAGGGAAAGCAGTACATCGCGCTGGCTTCGGGCGGAGC
GGTGATCGCGTTCGGGTTGCCGGAAAGCGGTAAGTGA

Upstream 100 bases:

>100_bases
CGCGCGACGCGGAATCCCTGATGCCGACCTACGGCAAGCAACTTTCCGCGAACGAACTCAATGATGTTGTGGTCTATCTC
TCGACTCTCGAGGTCAAGCC

Downstream 100 bases:

>100_bases
GATCACGTGGCGGCTCGGCATGAGGACGATCCTCAATGCGCTTTCCGTGAGCCCGAAGCGGAACTTAAGTGGGTCCGCCA
GTGTCCAACTTCGGGAGCAG

Product: pyrrolo-quinoline quinone

Products: NA

Alternate protein names: QH-EDH1; Quinohaemoprotein ethanol dehydrogenase type I [H]

Number of amino acids: Translated: 518; Mature: 518

Protein sequence:

>518_residues
MKRKLWIAVFALAAIGGAETGWQMYAGNYAGWRYSELAQINTSNVAALAPRWIFQTHVPGNMETTPLVQNGLMYLTAPSN
HAFALDLRTGHAIWHYSRTPPHPLNLCCGEVNRGFAVLGNRLFKVTIEDTLLALDIATGKPLWETTLGDYRKGYSGTLAP
LVVKDKVLVGTAGAEFGIRGFVDAYSPETGERLWRFYTIPLAGEPGGETWGKESNLRVGGSTWITGTYDPELNLTYWGTG
NPGPDMDGDVRPGDNLYTCSLVALDADTGKMKWHFQFTPHDTHDWDAISDPVLVDLAIEGRKVKAVIQANRNGYFYAIDR
TNGKFLFAQPYTKITWARGIGADGRPQVIPNLDPSHEGTRVCPGLGGGHNWQATAYSPLAGLYYFSSTDGCQNFFKNEGE
FVAGDWYQLSGTKEVPGEQPAGSFIAMDPATGKVRWRFEMLRNPSGGALATAGGLVFIGDSNGNLIGFDAKSGKVLWRFQ
TGAQISAPPVSYSFEGKQYIALASGGAVIAFGLPESGK

Sequences:

>Translated_518_residues
MKRKLWIAVFALAAIGGAETGWQMYAGNYAGWRYSELAQINTSNVAALAPRWIFQTHVPGNMETTPLVQNGLMYLTAPSN
HAFALDLRTGHAIWHYSRTPPHPLNLCCGEVNRGFAVLGNRLFKVTIEDTLLALDIATGKPLWETTLGDYRKGYSGTLAP
LVVKDKVLVGTAGAEFGIRGFVDAYSPETGERLWRFYTIPLAGEPGGETWGKESNLRVGGSTWITGTYDPELNLTYWGTG
NPGPDMDGDVRPGDNLYTCSLVALDADTGKMKWHFQFTPHDTHDWDAISDPVLVDLAIEGRKVKAVIQANRNGYFYAIDR
TNGKFLFAQPYTKITWARGIGADGRPQVIPNLDPSHEGTRVCPGLGGGHNWQATAYSPLAGLYYFSSTDGCQNFFKNEGE
FVAGDWYQLSGTKEVPGEQPAGSFIAMDPATGKVRWRFEMLRNPSGGALATAGGLVFIGDSNGNLIGFDAKSGKVLWRFQ
TGAQISAPPVSYSFEGKQYIALASGGAVIAFGLPESGK
>Mature_518_residues
MKRKLWIAVFALAAIGGAETGWQMYAGNYAGWRYSELAQINTSNVAALAPRWIFQTHVPGNMETTPLVQNGLMYLTAPSN
HAFALDLRTGHAIWHYSRTPPHPLNLCCGEVNRGFAVLGNRLFKVTIEDTLLALDIATGKPLWETTLGDYRKGYSGTLAP
LVVKDKVLVGTAGAEFGIRGFVDAYSPETGERLWRFYTIPLAGEPGGETWGKESNLRVGGSTWITGTYDPELNLTYWGTG
NPGPDMDGDVRPGDNLYTCSLVALDADTGKMKWHFQFTPHDTHDWDAISDPVLVDLAIEGRKVKAVIQANRNGYFYAIDR
TNGKFLFAQPYTKITWARGIGADGRPQVIPNLDPSHEGTRVCPGLGGGHNWQATAYSPLAGLYYFSSTDGCQNFFKNEGE
FVAGDWYQLSGTKEVPGEQPAGSFIAMDPATGKVRWRFEMLRNPSGGALATAGGLVFIGDSNGNLIGFDAKSGKVLWRFQ
TGAQISAPPVSYSFEGKQYIALASGGAVIAFGLPESGK

Specific function: Catalyzes the dye-linked oxidation of primary alcohols to the corresponding aldehydes and the (subsequent) oxidation of the aldehydes to carboxylic acids [H]

COG id: COG4993

COG function: function code G; Glucose dehydrogenase

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cytochrome c domain [H]

Homologues:

Organism=Escherichia coli, GI1786316, Length=407, Percent_Identity=27.7641277641278, Blast_Score=135, Evalue=7e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009056
- InterPro:   IPR019556
- InterPro:   IPR019551
- InterPro:   IPR018391
- InterPro:   IPR017512
- InterPro:   IPR002372
- InterPro:   IPR011047
- InterPro:   IPR001479 [H]

Pfam domain/function: PF01011 PQQ; PF10535 PQQ_C; PF10527 PQQ_N [H]

EC number: =1.1.98.1 [H]

Molecular weight: Translated: 56261; Mature: 56261

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRKLWIAVFALAAIGGAETGWQMYAGNYAGWRYSELAQINTSNVAALAPRWIFQTHVPG
CCCEEEEEEEEHHHCCCCCCCCEEEECCCCCCCHHHHEEECCCCEEEECCCEEEEEECCC
NMETTPLVQNGLMYLTAPSNHAFALDLRTGHAIWHYSRTPPHPLNLCCGEVNRGFAVLGN
CCCCCCCHHCCEEEEECCCCCEEEEEECCCCEEEEECCCCCCCHHHEECCCCCCCEEECC
RLFKVTIEDTLLALDIATGKPLWETTLGDYRKGYSGTLAPLVVKDKVLVGTAGAEFGIRG
EEEEEEEECEEEEEEECCCCCHHHHHHHHHHCCCCCCEEEEEEECEEEEEECCCCCCCEE
FVDAYSPETGERLWRFYTIPLAGEPGGETWGKESNLRVGGSTWITGTYDPELNLTYWGTG
EEECCCCCCCCEEEEEEEEEECCCCCCCCCCCCCCEEECCCEEEEEEECCCEEEEEEECC
NPGPDMDGDVRPGDNLYTCSLVALDADTGKMKWHFQFTPHDTHDWDAISDPVLVDLAIEG
CCCCCCCCCCCCCCCEEEEEEEEEECCCCCEEEEEEECCCCCCCCCCCCCCEEEEEEECC
RKVKAVIQANRNGYFYAIDRTNGKFLFAQPYTKITWARGIGADGRPQVIPNLDPSHEGTR
CEEEEEEEECCCCEEEEEECCCCEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCCCE
VCPGLGGGHNWQATAYSPLAGLYYFSSTDGCQNFFKNEGEFVAGDWYQLSGTKEVPGEQP
ECCCCCCCCCCCEEEECCCEEEEEEECCHHHHHHHCCCCCEEECCEEEECCCCCCCCCCC
AGSFIAMDPATGKVRWRFEMLRNPSGGALATAGGLVFIGDSNGNLIGFDAKSGKVLWRFQ
CCCEEEECCCCCEEEEEEEEECCCCCCEEEECCCEEEEECCCCCEEEEECCCCEEEEEEE
TGAQISAPPVSYSFEGKQYIALASGGAVIAFGLPESGK
CCCEECCCCCEEEECCCEEEEEECCCEEEEEECCCCCC
>Mature Secondary Structure
MKRKLWIAVFALAAIGGAETGWQMYAGNYAGWRYSELAQINTSNVAALAPRWIFQTHVPG
CCCEEEEEEEEHHHCCCCCCCCEEEECCCCCCCHHHHEEECCCCEEEECCCEEEEEECCC
NMETTPLVQNGLMYLTAPSNHAFALDLRTGHAIWHYSRTPPHPLNLCCGEVNRGFAVLGN
CCCCCCCHHCCEEEEECCCCCEEEEEECCCCEEEEECCCCCCCHHHEECCCCCCCEEECC
RLFKVTIEDTLLALDIATGKPLWETTLGDYRKGYSGTLAPLVVKDKVLVGTAGAEFGIRG
EEEEEEEECEEEEEEECCCCCHHHHHHHHHHCCCCCCEEEEEEECEEEEEECCCCCCCEE
FVDAYSPETGERLWRFYTIPLAGEPGGETWGKESNLRVGGSTWITGTYDPELNLTYWGTG
EEECCCCCCCCEEEEEEEEEECCCCCCCCCCCCCCEEECCCEEEEEEECCCEEEEEEECC
NPGPDMDGDVRPGDNLYTCSLVALDADTGKMKWHFQFTPHDTHDWDAISDPVLVDLAIEG
CCCCCCCCCCCCCCCEEEEEEEEEECCCCCEEEEEEECCCCCCCCCCCCCCEEEEEEECC
RKVKAVIQANRNGYFYAIDRTNGKFLFAQPYTKITWARGIGADGRPQVIPNLDPSHEGTR
CEEEEEEEECCCCEEEEEECCCCEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCCCE
VCPGLGGGHNWQATAYSPLAGLYYFSSTDGCQNFFKNEGEFVAGDWYQLSGTKEVPGEQP
ECCCCCCCCCCCEEEECCCEEEEEEECCHHHHHHHCCCCCEEECCEEEECCCCCCCCCCC
AGSFIAMDPATGKVRWRFEMLRNPSGGALATAGGLVFIGDSNGNLIGFDAKSGKVLWRFQ
CCCEEEECCCCCEEEEEEEEECCCCCCEEEECCCEEEEECCCCCEEEEECCCCEEEEEEE
TGAQISAPPVSYSFEGKQYIALASGGAVIAFGLPESGK
CCCEECCCCCEEEECCCEEEEEECCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8654419; 7601151; 3521592; 11679760; 11714714 [H]