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The map label for this gene is qheDH [H]

Identifier: 116622178

GI number: 116622178

Start: 3877371

End: 3879008

Strand: Reverse

Name: qheDH [H]

Synonym: Acid_3070

Alternate gene names: 116622178

Gene position: 3879008-3877371 (Counterclockwise)

Preceding gene: 116622179

Following gene: 116622177

Centisome position: 38.92

GC content: 62.09

Gene sequence:

>1638_bases
ATGAAATTGCGCCGGCTTCTGCTCCTCATTCTTTTCGCGCCCGTGCTGTTGGCGCCCGTGCTGTTGGCGCCCGTGCTCCA
GGCTCAAGGCCTTGACCCCGGCGCTTTGACTCTCTTTCACCAGCCTAAGGACGCCTGGCCGACTTACAACGGAGATTATT
CCGGCCGACGCTTCTCGGAGTTGGACCAGATCAACCAAGCAACGGTCGATCTGCTCAAGATCGAGTGGATGTACCGCCTC
AACGTGGGACCGCAGCGCGGCGTCGGGGGTCCCACGATCAAATCCACACCCCTGCTGGTGAACGGCATCCTCTACTTCAC
GATTCCCGATCACATCTTCGCGGTCAACGCCCGCACCGGCGAACACCTCTGGCAGTACGATTTCGAAGACAAGGGCGGCC
ACCTCGTGGGCCAGCGCGGAGTCGGCATTTATGGAGAGTGGCTCTACTTCGTCAGCCCCGACGGCTGGTTCATCTCGGTG
AACGCCAAAGACGGCAAAGAGCGCTGGAAGAAGAAGATCGCCGATGAGAAACTTCAGTACTTCACCACCATGGCGCCGCT
CATCGTGAAGAACCACGTCCTGGTCGGAATCGGCGGCGACGCGATGGATGTTCGGGGCTATCTGGAATCGCGCGATCCCG
AGACCGGCGAGTTGCAATGGCGCTGGTACACCACGCCTGAGAAAATGGGCGACCCGGGATCGGAGACGTGGCCCAACCTC
GAAGCAATGCATCACGGCGGCGGCATGACGTGGCTTCCCGGCACCTACGATCCCGACCTCAACCTGCTGTACTGGGGCAC
CGGCAATGCCAATCCGGTTTTCGCAGGCCAAGGCAGAAAAGGCGCGAATCTCTGGACCGCGTCGATCGTGGCGCTGAATC
CGGATACCGGCAAACTCGCCTGGTATTTCCAGGCATCGCCGCACGACACGCACGACTGGGACAACGTAGAGACGCCCGTA
TTGCTCGACGCCACCATCAACGGCCAACCGCGCAAACTGTTGGCGCAGGCGGCGCGCGCCGGATGGTTCTTCGTTCTGGA
CCGCACCAACGGGAAGAACCTGGTGTCGAAACCGTTCGCAGGCACCGGTAACTGGGCGCTCGGCGTCGATCCCAAGGGCC
AGCCGATTCCGAATCCGGAAAAGGAGCCGAAGGTCAATGGCGCCATGATCGATATGCCGGCCATGGGAGCCACGAACTGG
CCCCCGCCGAGCTACGATCCGCAGACCGAGTTGTTCTACTTCAACGGCACCACGGGCTACGGCGTGGCGTACCTCTACGA
CACCTCCGACAAACCCGAGGGCTACGGCGGTGGCGGCGGAGGCAATTTCGATTCGCACTCCGCACTTTTCGCAATGGACA
TTCGCACGGGAGCCATCAAGTGGAAACATGAGCATGGCGGCGAAGGCGGCGCCGCAATGAGCGGAGGTGTCCTGACCACG
GCGGGCAAGCTGCTGTTCACGGGCGATTCCGGCGAACTCGTGGCGTTCGACCCCGCGACCGGCAAGCCCATGTGGCGCCA
GCGCATGACGCAGTCTTTGAGCAACGGACCGTCGTCCTGGATGTTGGACGGGAAGCAGTACCTGATCGTCGCCGGCGGAG
ACACGCTCTATGCGCTCACGCTGGCCGGGAAACGGTGA

Upstream 100 bases:

>100_bases
AAGTCGAAATCGAAGACCGCTTGACCGGCCACCGCGCCCTGCTGCCGAAGTACACCGACGCGGACATCCATAACCTCACA
GCCTATCTGGTGACTCTGAA

Downstream 100 bases:

>100_bases
CGCGATGAAGCGACTCGCACTCGGCATCGGACTGGCGGCCGCTGCTTTCGCGCAGCAGGCGCCGCGCCGCATCCTCTCTC
CGGAAGTACTGCCCGATCGC

Product: pyrrolo-quinoline quinone

Products: NA

Alternate protein names: QH-EDH1; Quinohaemoprotein ethanol dehydrogenase type I [H]

Number of amino acids: Translated: 545; Mature: 545

Protein sequence:

>545_residues
MKLRRLLLLILFAPVLLAPVLLAPVLQAQGLDPGALTLFHQPKDAWPTYNGDYSGRRFSELDQINQATVDLLKIEWMYRL
NVGPQRGVGGPTIKSTPLLVNGILYFTIPDHIFAVNARTGEHLWQYDFEDKGGHLVGQRGVGIYGEWLYFVSPDGWFISV
NAKDGKERWKKKIADEKLQYFTTMAPLIVKNHVLVGIGGDAMDVRGYLESRDPETGELQWRWYTTPEKMGDPGSETWPNL
EAMHHGGGMTWLPGTYDPDLNLLYWGTGNANPVFAGQGRKGANLWTASIVALNPDTGKLAWYFQASPHDTHDWDNVETPV
LLDATINGQPRKLLAQAARAGWFFVLDRTNGKNLVSKPFAGTGNWALGVDPKGQPIPNPEKEPKVNGAMIDMPAMGATNW
PPPSYDPQTELFYFNGTTGYGVAYLYDTSDKPEGYGGGGGGNFDSHSALFAMDIRTGAIKWKHEHGGEGGAAMSGGVLTT
AGKLLFTGDSGELVAFDPATGKPMWRQRMTQSLSNGPSSWMLDGKQYLIVAGGDTLYALTLAGKR

Sequences:

>Translated_545_residues
MKLRRLLLLILFAPVLLAPVLLAPVLQAQGLDPGALTLFHQPKDAWPTYNGDYSGRRFSELDQINQATVDLLKIEWMYRL
NVGPQRGVGGPTIKSTPLLVNGILYFTIPDHIFAVNARTGEHLWQYDFEDKGGHLVGQRGVGIYGEWLYFVSPDGWFISV
NAKDGKERWKKKIADEKLQYFTTMAPLIVKNHVLVGIGGDAMDVRGYLESRDPETGELQWRWYTTPEKMGDPGSETWPNL
EAMHHGGGMTWLPGTYDPDLNLLYWGTGNANPVFAGQGRKGANLWTASIVALNPDTGKLAWYFQASPHDTHDWDNVETPV
LLDATINGQPRKLLAQAARAGWFFVLDRTNGKNLVSKPFAGTGNWALGVDPKGQPIPNPEKEPKVNGAMIDMPAMGATNW
PPPSYDPQTELFYFNGTTGYGVAYLYDTSDKPEGYGGGGGGNFDSHSALFAMDIRTGAIKWKHEHGGEGGAAMSGGVLTT
AGKLLFTGDSGELVAFDPATGKPMWRQRMTQSLSNGPSSWMLDGKQYLIVAGGDTLYALTLAGKR
>Mature_545_residues
MKLRRLLLLILFAPVLLAPVLLAPVLQAQGLDPGALTLFHQPKDAWPTYNGDYSGRRFSELDQINQATVDLLKIEWMYRL
NVGPQRGVGGPTIKSTPLLVNGILYFTIPDHIFAVNARTGEHLWQYDFEDKGGHLVGQRGVGIYGEWLYFVSPDGWFISV
NAKDGKERWKKKIADEKLQYFTTMAPLIVKNHVLVGIGGDAMDVRGYLESRDPETGELQWRWYTTPEKMGDPGSETWPNL
EAMHHGGGMTWLPGTYDPDLNLLYWGTGNANPVFAGQGRKGANLWTASIVALNPDTGKLAWYFQASPHDTHDWDNVETPV
LLDATINGQPRKLLAQAARAGWFFVLDRTNGKNLVSKPFAGTGNWALGVDPKGQPIPNPEKEPKVNGAMIDMPAMGATNW
PPPSYDPQTELFYFNGTTGYGVAYLYDTSDKPEGYGGGGGGNFDSHSALFAMDIRTGAIKWKHEHGGEGGAAMSGGVLTT
AGKLLFTGDSGELVAFDPATGKPMWRQRMTQSLSNGPSSWMLDGKQYLIVAGGDTLYALTLAGKR

Specific function: Catalyzes the dye-linked oxidation of primary alcohols to the corresponding aldehydes and the (subsequent) oxidation of the aldehydes to carboxylic acids [H]

COG id: COG4993

COG function: function code G; Glucose dehydrogenase

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cytochrome c domain [H]

Homologues:

Organism=Escherichia coli, GI1786316, Length=353, Percent_Identity=31.1614730878187, Blast_Score=134, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009056
- InterPro:   IPR019556
- InterPro:   IPR019551
- InterPro:   IPR018391
- InterPro:   IPR017512
- InterPro:   IPR002372
- InterPro:   IPR011047
- InterPro:   IPR001479 [H]

Pfam domain/function: PF01011 PQQ; PF10535 PQQ_C; PF10527 PQQ_N [H]

EC number: =1.1.98.1 [H]

Molecular weight: Translated: 59734; Mature: 59734

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLRRLLLLILFAPVLLAPVLLAPVLQAQGLDPGALTLFHQPKDAWPTYNGDYSGRRFSE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHH
LDQINQATVDLLKIEWMYRLNVGPQRGVGGPTIKSTPLLVNGILYFTIPDHIFAVNARTG
HHHHHHHHEEEEEEEEEEEECCCCCCCCCCCCCCCCCEEEEEEEEEEECCEEEEEECCCC
EHLWQYDFEDKGGHLVGQRGVGIYGEWLYFVSPDGWFISVNAKDGKERWKKKIADEKLQY
CCEEEECCCCCCCEEEECCCCCEEEEEEEEECCCCEEEEEECCCHHHHHHHHHHHHHHHH
FTTMAPLIVKNHVLVGIGGDAMDVRGYLESRDPETGELQWRWYTTPEKMGDPGSETWPNL
HHHHHHHHHCCEEEEEECCCCEEHHHHHHCCCCCCCEEEEEEECCHHHCCCCCCCCCCCC
EAMHHGGGMTWLPGTYDPDLNLLYWGTGNANPVFAGQGRKGANLWTASIVALNPDTGKLA
CEEECCCCEEECCCCCCCCCCEEEEECCCCCEEEECCCCCCCCEEEEEEEEECCCCCCEE
WYFQASPHDTHDWDNVETPVLLDATINGQPRKLLAQAARAGWFFVLDRTNGKNLVSKPFA
EEEECCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCEEEEEECCCCCCHHCCCCC
GTGNWALGVDPKGQPIPNPEKEPKVNGAMIDMPAMGATNWPPPSYDPQTELFYFNGTTGY
CCCCEEEECCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCC
GVAYLYDTSDKPEGYGGGGGGNFDSHSALFAMDIRTGAIKWKHEHGGEGGAAMSGGVLTT
EEEEEEECCCCCCCCCCCCCCCCCCCCEEEEEEEECCEEEEECCCCCCCCCEECCCEEEE
AGKLLFTGDSGELVAFDPATGKPMWRQRMTQSLSNGPSSWMLDGKQYLIVAGGDTLYALT
CCEEEEECCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCEEECCCEEEEEECCCEEEEEE
LAGKR
EECCC
>Mature Secondary Structure
MKLRRLLLLILFAPVLLAPVLLAPVLQAQGLDPGALTLFHQPKDAWPTYNGDYSGRRFSE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHH
LDQINQATVDLLKIEWMYRLNVGPQRGVGGPTIKSTPLLVNGILYFTIPDHIFAVNARTG
HHHHHHHHEEEEEEEEEEEECCCCCCCCCCCCCCCCCEEEEEEEEEEECCEEEEEECCCC
EHLWQYDFEDKGGHLVGQRGVGIYGEWLYFVSPDGWFISVNAKDGKERWKKKIADEKLQY
CCEEEECCCCCCCEEEECCCCCEEEEEEEEECCCCEEEEEECCCHHHHHHHHHHHHHHHH
FTTMAPLIVKNHVLVGIGGDAMDVRGYLESRDPETGELQWRWYTTPEKMGDPGSETWPNL
HHHHHHHHHCCEEEEEECCCCEEHHHHHHCCCCCCCEEEEEEECCHHHCCCCCCCCCCCC
EAMHHGGGMTWLPGTYDPDLNLLYWGTGNANPVFAGQGRKGANLWTASIVALNPDTGKLA
CEEECCCCEEECCCCCCCCCCEEEEECCCCCEEEECCCCCCCCEEEEEEEEECCCCCCEE
WYFQASPHDTHDWDNVETPVLLDATINGQPRKLLAQAARAGWFFVLDRTNGKNLVSKPFA
EEEECCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCEEEEEECCCCCCHHCCCCC
GTGNWALGVDPKGQPIPNPEKEPKVNGAMIDMPAMGATNWPPPSYDPQTELFYFNGTTGY
CCCCEEEECCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCC
GVAYLYDTSDKPEGYGGGGGGNFDSHSALFAMDIRTGAIKWKHEHGGEGGAAMSGGVLTT
EEEEEEECCCCCCCCCCCCCCCCCCCCEEEEEEEECCEEEEECCCCCCCCCEECCCEEEE
AGKLLFTGDSGELVAFDPATGKPMWRQRMTQSLSNGPSSWMLDGKQYLIVAGGDTLYALT
CCEEEEECCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCEEECCCEEEEEECCCEEEEEE
LAGKR
EECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8654419; 7601151; 3521592; 11679760; 11714714 [H]