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The map label for this gene is ackA

Identifier: 116622149

GI number: 116622149

Start: 3838371

End: 3839615

Strand: Direct

Name: ackA

Synonym: Acid_3041

Alternate gene names: 116622149

Gene position: 3838371-3839615 (Clockwise)

Preceding gene: 116622148

Following gene: 116622153

Centisome position: 38.52

GC content: 59.52

Gene sequence:

>1245_bases
ATGAATGTTCTCGTGCTCAACGCGGGTAGTTCGAGTCTGAAATTCCAGATCATCGCTACCGACCTCGAACGCATCCAACG
CGATAGCGACGAGCGCTTGTGCCACGGCTATGTCGAAAGGATCGGTGGTGAGGCCATTATCACGGTCGAGCCGCGCGGTG
GCCCTCGAAAAAAAGTGACGGCCCCGGTTCGCAATATCGCGGCGGCCCTTGACTACGTACTGCGATGGCTGGCTTCCGAT
CAGTCAGGGGTCGCGGAAATCCGCAGCCTGAGTGATGTGCACGCAGTGGGGCACCGCGTGGTCCATGGCGGTGAGGTGTT
TCGCGAGTCGGCGGTGATAACCGATGAAGTTCTGCAAGGGATAGAGGACTGCATCGACCTGGCGCCTTTGCACAATCCGA
ACAACATAAAGGGTATCCTCGCGGCGCGCGATGCCTTTGGCAGCGGCATGCCGCAAGTAGCGGTCTTCGATACGGCCTTT
CACACCTCGCTTCCCGATCACGCCTACTTGTATGCGATGCCCTATCACTTGTATGCGCGGCACCGCATCCGGCGTTACGG
CTTCCACGGGACATCCAACCGGTACGTCGCCTATCGCTATCGGACCCTTCGGCAACTGACGCGGGAGCAGACCAATATCA
TCACCCTGCACTTGGGCAACGGCTGTTCCGCCACCGCAATCCGAAACGGTCGATCGATGGATACCTCGATGGGCATGACC
CCCCTGGAAGGTTTGGTGATGGGGACACGGTCGGGCGATCTCGATCCCGCGATCCTCAGTCTGATTGCCACGAAGGAGGG
CTTGTCCCCAACCGAAGTTGAGGCCCTGCTGAACACGCAGTGCGGACTGCTGGGAATCTCCGGCGTGACCAACGATATGA
AAGTATTGTTGCAGGAACTGCGAGAGCACGATGACCGGCGCATCCGCCTGGCAATCGAGATCTTCTGCTATCGTGCACGG
AAGTACATTGGAGCGCTGCTGGCTTGCATGGGCGGAGCCGACGCGGTGATCTTTACTGGAGGAATCGGCGAGAACGCACC
CGAGATTCGCGCGCGTATTTGCGCGGGGCTCGAGTGGGCTGGGCTGGAGATCGATTCCGACCAAAATGCCCAAACCATGG
GGCGGCCACAGCAAATTAGCAAACCCGAATCCAGGTTGCAGGCATGGGTCATCCCGACCGACGAAGAACTGCTCATCGCC
CGTGATACCGTGCGCTGCATTCTAGGCGAGCCCCACCCTGCGTAG

Upstream 100 bases:

>100_bases
AAAGGTAAAGAGCCTGAGACTGGTAAAGCCGCCCAAACCCAAAGCGCGCTAACAACAAGCGTTCGCTGGATCTGGATCTG
TGAGAATGGTGGTGACACTT

Downstream 100 bases:

>100_bases
GTCGTACGAGTTTCTACGCCGGCAACTGAGTAGGACCGGCCGCTTTGGCCGGTCCATCCCGGCTCACAGATATCTGCCCA
CCAGATTTTCGATCATCTCC

Product: acetate kinase

Products: NA

Alternate protein names: Acetokinase

Number of amino acids: Translated: 414; Mature: 414

Protein sequence:

>414_residues
MNVLVLNAGSSSLKFQIIATDLERIQRDSDERLCHGYVERIGGEAIITVEPRGGPRKKVTAPVRNIAAALDYVLRWLASD
QSGVAEIRSLSDVHAVGHRVVHGGEVFRESAVITDEVLQGIEDCIDLAPLHNPNNIKGILAARDAFGSGMPQVAVFDTAF
HTSLPDHAYLYAMPYHLYARHRIRRYGFHGTSNRYVAYRYRTLRQLTREQTNIITLHLGNGCSATAIRNGRSMDTSMGMT
PLEGLVMGTRSGDLDPAILSLIATKEGLSPTEVEALLNTQCGLLGISGVTNDMKVLLQELREHDDRRIRLAIEIFCYRAR
KYIGALLACMGGADAVIFTGGIGENAPEIRARICAGLEWAGLEIDSDQNAQTMGRPQQISKPESRLQAWVIPTDEELLIA
RDTVRCILGEPHPA

Sequences:

>Translated_414_residues
MNVLVLNAGSSSLKFQIIATDLERIQRDSDERLCHGYVERIGGEAIITVEPRGGPRKKVTAPVRNIAAALDYVLRWLASD
QSGVAEIRSLSDVHAVGHRVVHGGEVFRESAVITDEVLQGIEDCIDLAPLHNPNNIKGILAARDAFGSGMPQVAVFDTAF
HTSLPDHAYLYAMPYHLYARHRIRRYGFHGTSNRYVAYRYRTLRQLTREQTNIITLHLGNGCSATAIRNGRSMDTSMGMT
PLEGLVMGTRSGDLDPAILSLIATKEGLSPTEVEALLNTQCGLLGISGVTNDMKVLLQELREHDDRRIRLAIEIFCYRAR
KYIGALLACMGGADAVIFTGGIGENAPEIRARICAGLEWAGLEIDSDQNAQTMGRPQQISKPESRLQAWVIPTDEELLIA
RDTVRCILGEPHPA
>Mature_414_residues
MNVLVLNAGSSSLKFQIIATDLERIQRDSDERLCHGYVERIGGEAIITVEPRGGPRKKVTAPVRNIAAALDYVLRWLASD
QSGVAEIRSLSDVHAVGHRVVHGGEVFRESAVITDEVLQGIEDCIDLAPLHNPNNIKGILAARDAFGSGMPQVAVFDTAF
HTSLPDHAYLYAMPYHLYARHRIRRYGFHGTSNRYVAYRYRTLRQLTREQTNIITLHLGNGCSATAIRNGRSMDTSMGMT
PLEGLVMGTRSGDLDPAILSLIATKEGLSPTEVEALLNTQCGLLGISGVTNDMKVLLQELREHDDRRIRLAIEIFCYRAR
KYIGALLACMGGADAVIFTGGIGENAPEIRARICAGLEWAGLEIDSDQNAQTMGRPQQISKPESRLQAWVIPTDEELLIA
RDTVRCILGEPHPA

Specific function: Involved In The Activation Of Acetate To Acetyl CoA And The Secretion Of Acetate. During Anaerobic Growth Of The Organism, This Enzyme Is Also Involved In The Synthesis Of Most Of The ATP Formed Catabolically. [C]

COG id: COG0282

COG function: function code C; Acetate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetokinase family

Homologues:

Organism=Escherichia coli, GI1788633, Length=411, Percent_Identity=43.5523114355231, Blast_Score=298, Evalue=3e-82,
Organism=Escherichia coli, GI145693184, Length=409, Percent_Identity=42.2982885085575, Blast_Score=291, Evalue=7e-80,

Paralogues:

None

Copy number: 1,800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ACKA_SOLUE (Q022T0)

Other databases:

- EMBL:   CP000473
- RefSeq:   YP_824305.1
- ProteinModelPortal:   Q022T0
- SMR:   Q022T0
- STRING:   Q022T0
- GeneID:   4428759
- GenomeReviews:   CP000473_GR
- KEGG:   sus:Acid_3041
- NMPDR:   fig|234267.9.peg.2885
- eggNOG:   COG0282
- HOGENOM:   HBG285863
- OMA:   PHLKDKN
- PhylomeDB:   Q022T0
- ProtClustDB:   PRK00180
- GO:   GO:0005737
- HAMAP:   MF_00020
- InterPro:   IPR000890
- InterPro:   IPR004372
- PANTHER:   PTHR21060
- PANTHER:   PTHR21060:SF11
- PIRSF:   PIRSF000722
- PRINTS:   PR00471
- TIGRFAMs:   TIGR00016

Pfam domain/function: PF00871 Acetate_kinase

EC number: =2.7.2.1

Molecular weight: Translated: 45488; Mature: 45488

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: PS01075 ACETATE_KINASE_1; PS01076 ACETATE_KINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVLVLNAGSSSLKFQIIATDLERIQRDSDERLCHGYVERIGGEAIITVEPRGGPRKKVT
CEEEEEECCCCCEEEEEEEHHHHHHHCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCHH
APVRNIAAALDYVLRWLASDQSGVAEIRSLSDVHAVGHRVVHGGEVFRESAVITDEVLQG
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHH
IEDCIDLAPLHNPNNIKGILAARDAFGSGMPQVAVFDTAFHTSLPDHAYLYAMPYHLYAR
HHHHHHHCCCCCCCCCEEEEEEHHHHCCCCCCEEEEEHHHHCCCCCCEEEEEEHHHHHHH
HRIRRYGFHGTSNRYVAYRYRTLRQLTREQTNIITLHLGNGCSATAIRNGRSMDTSMGMT
HHHHHHCCCCCCCCEEEHHHHHHHHHHHCCCCEEEEEECCCCCCCEECCCCCCCCCCCCC
PLEGLVMGTRSGDLDPAILSLIATKEGLSPTEVEALLNTQCGLLGISGVTNDMKVLLQEL
CHHHEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHCCCCCEEECCCCCHHHHHHHHHH
REHDDRRIRLAIEIFCYRARKYIGALLACMGGADAVIFTGGIGENAPEIRARICAGLEWA
HHCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHCCCEEE
GLEIDSDQNAQTMGRPQQISKPESRLQAWVIPTDEELLIARDTVRCILGEPHPA
CEEECCCCCHHHCCCCHHCCCCHHHCEEEEECCCCCEEEEHHHHHHCCCCCCCC
>Mature Secondary Structure
MNVLVLNAGSSSLKFQIIATDLERIQRDSDERLCHGYVERIGGEAIITVEPRGGPRKKVT
CEEEEEECCCCCEEEEEEEHHHHHHHCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCHH
APVRNIAAALDYVLRWLASDQSGVAEIRSLSDVHAVGHRVVHGGEVFRESAVITDEVLQG
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHH
IEDCIDLAPLHNPNNIKGILAARDAFGSGMPQVAVFDTAFHTSLPDHAYLYAMPYHLYAR
HHHHHHHCCCCCCCCCEEEEEEHHHHCCCCCCEEEEEHHHHCCCCCCEEEEEEHHHHHHH
HRIRRYGFHGTSNRYVAYRYRTLRQLTREQTNIITLHLGNGCSATAIRNGRSMDTSMGMT
HHHHHHCCCCCCCCEEEHHHHHHHHHHHCCCCEEEEEECCCCCCCEECCCCCCCCCCCCC
PLEGLVMGTRSGDLDPAILSLIATKEGLSPTEVEALLNTQCGLLGISGVTNDMKVLLQEL
CHHHEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHCCCCCEEECCCCCHHHHHHHHHH
REHDDRRIRLAIEIFCYRARKYIGALLACMGGADAVIFTGGIGENAPEIRARICAGLEWA
HHCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHCCCEEE
GLEIDSDQNAQTMGRPQQISKPESRLQAWVIPTDEELLIARDTVRCILGEPHPA
CEEECCCCCHHHCCCCHHCCCCHHHCEEEEECCCCCEEEEHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA