Click here to switch to the map view.

The map label for this gene is yccK [H]

Identifier: 116622026

GI number: 116622026

Start: 3691935

End: 3692927

Strand: Direct

Name: yccK [H]

Synonym: Acid_2911

Alternate gene names: 116622026

Gene position: 3691935-3692927 (Clockwise)

Preceding gene: 116622025

Following gene: 116622027

Centisome position: 37.05

GC content: 63.85

Gene sequence:

>993_bases
ATGCAAAAGCGAACACTGGGAAGAAGCGGATTGGAAGTCTCGGCGCTGGGCCTGGGCTGCATGGGAATGACGGGTGTCTA
CAATGCGCCCGTCGATCGGCAGGAGATGATCTCGTTGCTGCGCTCGGCAGTGGAGCGCGGCATTACTTTGTTCGATACGG
CGGAAGCCTACGGCCCGTTCGCGAACGAGGAACTTGTCGGTGAGGCTCTCGCTCCGGTTCGCGACCAAGTCGTGATCGCG
ACAAAGTTCGGCTTCGACATCGCCCCGGACGGGACGCGGCGGGGCGGCACGAACAGCCGCCCGGAGCACATTCGAGAAGT
TGCCGATGCCGCGCTGCGACGGTTGAAGACGGACGCAATCGATCTCTTCTATCAGCACCGCGTCGACCCCGCCGTGCCGA
TCGAGGATGTGGCTGGAGCGCTGAAAGAGCTTATCCAACAGGGGAAGGTGAGGCACTTCGGGATGTCGGAGGCCTCCGCC
GCGACCATTCGGCGCGCACATGCGGTCCAGCCGGTCACCGCCGTACAGAGCGAGTACTCGCTCTGGTGGCGCGAGGCTGA
GAAGGAGGTGCTACCAACGTGCGAGGAACTCGGAATCGGCTTCGTGCCGTTCAGCCCGCTCGGCGCGGGGTTCCTTACCG
GCAAGATCGACGAGAACACCAGCTTTGAAGGCAACGACTTCCGCAGCATGGTCCCTCGGTTCACGCCGGAAGCGCGCAAG
GCGAATCTGGCGTTTGTCGATTTGCTGCGTAGCGTTGCGGCGCGGAAGAACGCGACGCCTGCACAGATCGCGCTGGCATG
GCTGCTCGCGCAGAAGCCGTGGATCGTGCCGATTCCGGGTACGACGAAGCTGCACCGCCTGGAGGAGAACATCGGCGCTG
CATCCGTCGAACTCACGGCTGACGACCTGGGTGAGATCGCACGCGGGGCGGCCGGAATCGAGACACAGGGAGCACGCCTG
CCGCAAGCGGCGCTAGACATGGTCGGGCACTAA

Upstream 100 bases:

>100_bases
CTGGGTCATGGTTTCGGGCTCGGCATAGGTACGAGCGCCGAGGGGTGGATCTTGGACGCCATTCGGTTCTGGGCGGCGTC
CGTACGCAAGGAGAACTGAA

Downstream 100 bases:

>100_bases
GTGTGAGAGAGCGTATGAGAATCTTTGCAGCAATTCTGATCTCTGTGGGCCTGGCCGCATCAGGAGCATGGAGCCAGCCA
TCGACGGAGCAGGGTGCGAT

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MQKRTLGRSGLEVSALGLGCMGMTGVYNAPVDRQEMISLLRSAVERGITLFDTAEAYGPFANEELVGEALAPVRDQVVIA
TKFGFDIAPDGTRRGGTNSRPEHIREVADAALRRLKTDAIDLFYQHRVDPAVPIEDVAGALKELIQQGKVRHFGMSEASA
ATIRRAHAVQPVTAVQSEYSLWWREAEKEVLPTCEELGIGFVPFSPLGAGFLTGKIDENTSFEGNDFRSMVPRFTPEARK
ANLAFVDLLRSVAARKNATPAQIALAWLLAQKPWIVPIPGTTKLHRLEENIGAASVELTADDLGEIARGAAGIETQGARL
PQAALDMVGH

Sequences:

>Translated_330_residues
MQKRTLGRSGLEVSALGLGCMGMTGVYNAPVDRQEMISLLRSAVERGITLFDTAEAYGPFANEELVGEALAPVRDQVVIA
TKFGFDIAPDGTRRGGTNSRPEHIREVADAALRRLKTDAIDLFYQHRVDPAVPIEDVAGALKELIQQGKVRHFGMSEASA
ATIRRAHAVQPVTAVQSEYSLWWREAEKEVLPTCEELGIGFVPFSPLGAGFLTGKIDENTSFEGNDFRSMVPRFTPEARK
ANLAFVDLLRSVAARKNATPAQIALAWLLAQKPWIVPIPGTTKLHRLEENIGAASVELTADDLGEIARGAAGIETQGARL
PQAALDMVGH
>Mature_330_residues
MQKRTLGRSGLEVSALGLGCMGMTGVYNAPVDRQEMISLLRSAVERGITLFDTAEAYGPFANEELVGEALAPVRDQVVIA
TKFGFDIAPDGTRRGGTNSRPEHIREVADAALRRLKTDAIDLFYQHRVDPAVPIEDVAGALKELIQQGKVRHFGMSEASA
ATIRRAHAVQPVTAVQSEYSLWWREAEKEVLPTCEELGIGFVPFSPLGAGFLTGKIDENTSFEGNDFRSMVPRFTPEARK
ANLAFVDLLRSVAARKNATPAQIALAWLLAQKPWIVPIPGTTKLHRLEENIGAASVELTADDLGEIARGAAGIETQGARL
PQAALDMVGH

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=324, Percent_Identity=30.8641975308642, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI4504825, Length=321, Percent_Identity=30.8411214953271, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI27436964, Length=323, Percent_Identity=30.6501547987616, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI27436962, Length=323, Percent_Identity=30.6501547987616, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI27436966, Length=323, Percent_Identity=30.6501547987616, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI27436971, Length=322, Percent_Identity=30.7453416149068, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI223718702, Length=226, Percent_Identity=30.0884955752212, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI41152114, Length=298, Percent_Identity=26.510067114094, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI41327764, Length=197, Percent_Identity=27.9187817258883, Blast_Score=80, Evalue=2e-15,
Organism=Escherichia coli, GI1789375, Length=325, Percent_Identity=33.8461538461538, Blast_Score=156, Evalue=2e-39,
Organism=Escherichia coli, GI87081735, Length=320, Percent_Identity=32.8125, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1788070, Length=318, Percent_Identity=33.6477987421384, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1787674, Length=320, Percent_Identity=31.25, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1789199, Length=348, Percent_Identity=31.6091954022989, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI1788081, Length=308, Percent_Identity=26.2987012987013, Blast_Score=98, Evalue=7e-22,
Organism=Escherichia coli, GI48994888, Length=324, Percent_Identity=26.8518518518519, Blast_Score=88, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17566692, Length=306, Percent_Identity=27.4509803921569, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17564128, Length=326, Percent_Identity=23.0061349693252, Blast_Score=67, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6323998, Length=320, Percent_Identity=28.75, Blast_Score=120, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6325169, Length=327, Percent_Identity=28.1345565749235, Blast_Score=114, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6319958, Length=287, Percent_Identity=27.8745644599303, Blast_Score=110, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6325384, Length=342, Percent_Identity=28.9473684210526, Blast_Score=106, Evalue=6e-24,
Organism=Saccharomyces cerevisiae, GI6319951, Length=315, Percent_Identity=27.9365079365079, Blast_Score=106, Evalue=6e-24,
Organism=Saccharomyces cerevisiae, GI6322615, Length=245, Percent_Identity=29.7959183673469, Blast_Score=103, Evalue=5e-23,
Organism=Saccharomyces cerevisiae, GI6321052, Length=158, Percent_Identity=34.1772151898734, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24640980, Length=322, Percent_Identity=26.7080745341615, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI45549126, Length=322, Percent_Identity=26.7080745341615, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24646159, Length=224, Percent_Identity=28.125, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24646155, Length=162, Percent_Identity=30.8641975308642, Blast_Score=68, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 35721; Mature: 35721

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKRTLGRSGLEVSALGLGCMGMTGVYNAPVDRQEMISLLRSAVERGITLFDTAEAYGPF
CCCCCCCCCCCEEEECCCCHHCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEECHHHHCCC
ANEELVGEALAPVRDQVVIATKFGFDIAPDGTRRGGTNSRPEHIREVADAALRRLKTDAI
CCHHHHHHHHHCCCCCEEEEEECCCEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
DLFYQHRVDPAVPIEDVAGALKELIQQGKVRHFGMSEASAATIRRAHAVQPVTAVQSEYS
HHHHHHCCCCCCCHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHHHHCCHHHHHHHHHH
LWWREAEKEVLPTCEELGIGFVPFSPLGAGFLTGKIDENTSFEGNDFRSMVPRFTPEARK
HHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCEECCCCCCCCCCCCHHHHHCCCCCCCHHH
ANLAFVDLLRSVAARKNATPAQIALAWLLAQKPWIVPIPGTTKLHRLEENIGAASVELTA
CHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHCCCEEEEECH
DDLGEIARGAAGIETQGARLPQAALDMVGH
HHHHHHHHCCCCCCCCCCCCCHHHHHHHCC
>Mature Secondary Structure
MQKRTLGRSGLEVSALGLGCMGMTGVYNAPVDRQEMISLLRSAVERGITLFDTAEAYGPF
CCCCCCCCCCCEEEECCCCHHCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEECHHHHCCC
ANEELVGEALAPVRDQVVIATKFGFDIAPDGTRRGGTNSRPEHIREVADAALRRLKTDAI
CCHHHHHHHHHCCCCCEEEEEECCCEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
DLFYQHRVDPAVPIEDVAGALKELIQQGKVRHFGMSEASAATIRRAHAVQPVTAVQSEYS
HHHHHHCCCCCCCHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHHHHCCHHHHHHHHHH
LWWREAEKEVLPTCEELGIGFVPFSPLGAGFLTGKIDENTSFEGNDFRSMVPRFTPEARK
HHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCEECCCCCCCCCCCCHHHHHCCCCCCCHHH
ANLAFVDLLRSVAARKNATPAQIALAWLLAQKPWIVPIPGTTKLHRLEENIGAASVELTA
CHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHCCCEEEEECH
DDLGEIARGAAGIETQGARLPQAALDMVGH
HHHHHHHHCCCCCCCCCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9106203 [H]