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The map label for this gene is ccrM [H]

Identifier: 116622013

GI number: 116622013

Start: 3676104

End: 3676994

Strand: Direct

Name: ccrM [H]

Synonym: Acid_2898

Alternate gene names: 116622013

Gene position: 3676104-3676994 (Clockwise)

Preceding gene: 116622010

Following gene: 116622014

Centisome position: 36.89

GC content: 60.61

Gene sequence:

>891_bases
ATGATAGAACTCGACCAAGTAACCCAGATGGATTGCCTCAAAGCACTAGCGGACCTCCCGGACCAAGCCGTGGACGTCAC
CCTGACCGACCCACCATACCCGAACCGACTCAACCTCTTCAGTGACTCAATCGTCGACGGCTACGCCGGCCTGTACCTTG
CGTGCAAGAAGACGAAGAACTACGTCGTGTTCTTCTGGAGCAACGACAACATTCCCCAGGCACCGCCTGGCTGGTATGAG
GTCGCGCGCCACGTGTGGCACAAACCCGACTGCAAATCAATAACACACTATGAGCTCATCATCGTGTGGAGCCGCGACTA
CAAGCGAAAAACCAGCCGCGTGTGGAGCATCCCCATCCTCGATTACCGAAGTCTTCGGGATTGGAAGCCGCACCCCACAC
AAAAACCCGTCCGCCTCATCCGGTACCTCCTGGAGCAGTACACGAAAGAAGGCGACACCGTCTTGGACCCCTTCGTCGGC
ACCGGTACCACCGCCGTCGCATGCAAACAAATGCGCCGGCATTTCATCGCCATCGACAACGACCCTGCCTACATCAAAAT
GGCAACAGCCCGACTCACCACGCGTAGCAAACAAGACGACGCAGCACCGCAGGAAGCCACCGTCAAGGGCGAGGACGCAC
CGCCCGAAGACCCGGACGCAAGTTCCGAGGACGAGATCGCCGAGCACGCCGCACAAGACCAACCCATCGAAGACGAGACC
AACGACGAACCCGCACCAGACAATGCGGATGAAGCCCCGCCTCGCCACGCAGCGCGGACCACCTCACGCACACCGCGACC
AGCACAACGACCAGCAGAGAAGCCCCGGCGACCACCCAAACCCGCCAGCCGCGCCACACCGGCGCGGGAACCAGCGTACG
CAAAACGGTGA

Upstream 100 bases:

>100_bases
GGTGGGACCGAGGATAAAGACGTGCCGCAACATTTCCTGCCGCCGCAACCGGACATCGAACAACCCCTACCGGGGAGCGC
AACGGCGCTCCCCGTTTCTG

Downstream 100 bases:

>100_bases
AGAGTGATGCCTTCGCTGCAACTCTCCCGCCCCAACTTGCGCAAGCTCGCCCTTATCCTCGAACTGCACGACATCGATGC
CAAAGACAACGCAACATACA

Product: DNA methylase N-4/N-6 domain-containing protein

Products: NA

Alternate protein names: M.BabI; Adenine-specific methyltransferase BabI; DNA methyltransferase CcrM; M.CcrMI ortholog [H]

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MIELDQVTQMDCLKALADLPDQAVDVTLTDPPYPNRLNLFSDSIVDGYAGLYLACKKTKNYVVFFWSNDNIPQAPPGWYE
VARHVWHKPDCKSITHYELIIVWSRDYKRKTSRVWSIPILDYRSLRDWKPHPTQKPVRLIRYLLEQYTKEGDTVLDPFVG
TGTTAVACKQMRRHFIAIDNDPAYIKMATARLTTRSKQDDAAPQEATVKGEDAPPEDPDASSEDEIAEHAAQDQPIEDET
NDEPAPDNADEAPPRHAARTTSRTPRPAQRPAEKPRRPPKPASRATPAREPAYAKR

Sequences:

>Translated_296_residues
MIELDQVTQMDCLKALADLPDQAVDVTLTDPPYPNRLNLFSDSIVDGYAGLYLACKKTKNYVVFFWSNDNIPQAPPGWYE
VARHVWHKPDCKSITHYELIIVWSRDYKRKTSRVWSIPILDYRSLRDWKPHPTQKPVRLIRYLLEQYTKEGDTVLDPFVG
TGTTAVACKQMRRHFIAIDNDPAYIKMATARLTTRSKQDDAAPQEATVKGEDAPPEDPDASSEDEIAEHAAQDQPIEDET
NDEPAPDNADEAPPRHAARTTSRTPRPAQRPAEKPRRPPKPASRATPAREPAYAKR
>Mature_296_residues
MIELDQVTQMDCLKALADLPDQAVDVTLTDPPYPNRLNLFSDSIVDGYAGLYLACKKTKNYVVFFWSNDNIPQAPPGWYE
VARHVWHKPDCKSITHYELIIVWSRDYKRKTSRVWSIPILDYRSLRDWKPHPTQKPVRLIRYLLEQYTKEGDTVLDPFVG
TGTTAVACKQMRRHFIAIDNDPAYIKMATARLTTRSKQDDAAPQEATVKGEDAPPEDPDASSEDEIAEHAAQDQPIEDET
NDEPAPDNADEAPPRHAARTTSRTPRPAQRPAEKPRRPPKPASRATPAREPAYAKR

Specific function: This methylase recognizes the double-stranded sequence GANTC and causes specific methylation on A-2 on both strands. CcrM-mediated methylation has important cellular functions. Appears to contribute to the accurate cell-cycle control of DNA replication an

COG id: COG0863

COG function: function code L; DNA modification methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI87082238, Length=264, Percent_Identity=25.7575757575758, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002941
- InterPro:   IPR002052
- InterPro:   IPR001091 [H]

Pfam domain/function: PF01555 N6_N4_Mtase [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 33597; Mature: 33597

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIELDQVTQMDCLKALADLPDQAVDVTLTDPPYPNRLNLFSDSIVDGYAGLYLACKKTKN
CCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHCEEEEEECCCC
YVVFFWSNDNIPQAPPGWYEVARHVWHKPDCKSITHYELIIVWSRDYKRKTSRVWSIPIL
EEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCEEEEEEEECCCHHHHHCEEEECCCC
DYRSLRDWKPHPTQKPVRLIRYLLEQYTKEGDTVLDPFVGTGTTAVACKQMRRHFIAIDN
CHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHEEEECC
DPAYIKMATARLTTRSKQDDAAPQEATVKGEDAPPEDPDASSEDEIAEHAAQDQPIEDET
CCCEEEEEHHHHHHCCCCCCCCCCCCEECCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCC
NDEPAPDNADEAPPRHAARTTSRTPRPAQRPAEKPRRPPKPASRATPAREPAYAKR
CCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MIELDQVTQMDCLKALADLPDQAVDVTLTDPPYPNRLNLFSDSIVDGYAGLYLACKKTKN
CCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHCEEEEEECCCC
YVVFFWSNDNIPQAPPGWYEVARHVWHKPDCKSITHYELIIVWSRDYKRKTSRVWSIPIL
EEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCEEEEEEEECCCHHHHHCEEEECCCC
DYRSLRDWKPHPTQKPVRLIRYLLEQYTKEGDTVLDPFVGTGTTAVACKQMRRHFIAIDN
CHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHEEEECC
DPAYIKMATARLTTRSKQDDAAPQEATVKGEDAPPEDPDASSEDEIAEHAAQDQPIEDET
CCCEEEEEHHHHHHCCCCCCCCCCCCEECCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCC
NDEPAPDNADEAPPRHAARTTSRTPRPAQRPAEKPRRPPKPASRATPAREPAYAKR
CCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11756688 [H]