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The map label for this gene is yacO [H]

Identifier: 116621924

GI number: 116621924

Start: 3560518

End: 3561231

Strand: Reverse

Name: yacO [H]

Synonym: Acid_2809

Alternate gene names: 116621924

Gene position: 3561231-3560518 (Counterclockwise)

Preceding gene: 116621925

Following gene: 116621922

Centisome position: 35.74

GC content: 66.39

Gene sequence:

>714_bases
ATGGCCCTGTTGAGCGGTATTCATCCGGTTGTCGAAGCGCTGCGCGCGGGCAATCCCCTGGAGCGGATCGTGATCGCGCA
GGGTGCCGGCGGTCCGCGACTGCAGGAGATCATCGATCTCGCGCGCCAGGCAAAAATCCCCGTGCGATTCGAACCGCGCC
CTTCACTGGACCGCCTCGCCGGCTCATCCGCTCACCAGGGCGTGGTCGGACTAGGCGCCGCCCGCAAGTACGCCGACCTG
GATTCCGTCGCTGAAAGCGAGATGCTCGTGGTGCTCGATGGCGTGGAAGATCCGCACAATCTCGGCGCCATCGTGCGCAC
CGCCCATGCAGCCGGTGCCGGTGCCGTGATCGTGCCGGAGCGCCGCGCCGCCGGCGTCACCGACGTCGTCGCCAAGGCCG
CCGCCGGAGCGCTGGAGCACCTCCCGGTCGTCCGCGTCACCAACATCAATCGCGCGCTGGAAGATTTGAAGGAGCGCGGC
ATGTGGATCTACGGCCTGGACGAACGCGGCACCGAGTCCTACGACCAGATCGATTACGCGAAGAAGAGCGTGCTCGTTCT
CGGCGGCGAAGGCAAAGGTCTCCACGAGCAGGTCCGCAAACACTGCGACGTCCTGGTCCGCATACCGATGGCGGGCCAGA
TCTCATCGCTCAACGTCTCCGTCGCTGCCGGCGTAGTCCTCTTCGAATGGCGCCGACGGCGGCCAGTCCGTTAA

Upstream 100 bases:

>100_bases
CGCACGAACAGATCGTCGAAATCACCCTGGTGATCGCCATGGCCAACTTCACCAATCGCTTCAATAACGGCCTCGCGATT
CTGCCTGAGGCCTGATCGCG

Downstream 100 bases:

>100_bases
CCGCGGCTGCCAGCGGCCGGTGTCTAGTTGGCCGGCGCAATCGTTATTGGAAAGCTGACGGTAGCAGTCTGCATTGGCGA
ACTGGAGTCGGTTACTTTGA

Product: RNA methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 236

Protein sequence:

>237_residues
MALLSGIHPVVEALRAGNPLERIVIAQGAGGPRLQEIIDLARQAKIPVRFEPRPSLDRLAGSSAHQGVVGLGAARKYADL
DSVAESEMLVVLDGVEDPHNLGAIVRTAHAAGAGAVIVPERRAAGVTDVVAKAAAGALEHLPVVRVTNINRALEDLKERG
MWIYGLDERGTESYDQIDYAKKSVLVLGGEGKGLHEQVRKHCDVLVRIPMAGQISSLNVSVAAGVVLFEWRRRRPVR

Sequences:

>Translated_237_residues
MALLSGIHPVVEALRAGNPLERIVIAQGAGGPRLQEIIDLARQAKIPVRFEPRPSLDRLAGSSAHQGVVGLGAARKYADL
DSVAESEMLVVLDGVEDPHNLGAIVRTAHAAGAGAVIVPERRAAGVTDVVAKAAAGALEHLPVVRVTNINRALEDLKERG
MWIYGLDERGTESYDQIDYAKKSVLVLGGEGKGLHEQVRKHCDVLVRIPMAGQISSLNVSVAAGVVLFEWRRRRPVR
>Mature_236_residues
ALLSGIHPVVEALRAGNPLERIVIAQGAGGPRLQEIIDLARQAKIPVRFEPRPSLDRLAGSSAHQGVVGLGAARKYADLD
SVAESEMLVVLDGVEDPHNLGAIVRTAHAAGAGAVIVPERRAAGVTDVVAKAAAGALEHLPVVRVTNINRALEDLKERGM
WIYGLDERGTESYDQIDYAKKSVLVLGGEGKGLHEQVRKHCDVLVRIPMAGQISSLNVSVAAGVVLFEWRRRRPVR

Specific function: Unknown

COG id: COG0566

COG function: function code J; rRNA methylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase TrmH family [H]

Homologues:

Organism=Homo sapiens, GI40068479, Length=254, Percent_Identity=30.7086614173228, Blast_Score=104, Evalue=7e-23,
Organism=Homo sapiens, GI110825988, Length=154, Percent_Identity=31.1688311688312, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI1790623, Length=239, Percent_Identity=38.9121338912134, Blast_Score=163, Evalue=1e-41,
Organism=Escherichia coli, GI1790083, Length=154, Percent_Identity=33.1168831168831, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1788935, Length=207, Percent_Identity=27.536231884058, Blast_Score=73, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17555908, Length=243, Percent_Identity=31.2757201646091, Blast_Score=94, Evalue=6e-20,
Organism=Saccharomyces cerevisiae, GI6324775, Length=162, Percent_Identity=28.3950617283951, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004441
- InterPro:   IPR001537
- InterPro:   IPR013123 [H]

Pfam domain/function: PF00588 SpoU_methylase; PF08032 SpoU_sub_bind [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 25367; Mature: 25235

Theoretical pI: Translated: 9.06; Mature: 9.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALLSGIHPVVEALRAGNPLERIVIAQGAGGPRLQEIIDLARQAKIPVRFEPRPSLDRLA
CCHHHHHHHHHHHHHCCCCHHEEEEECCCCCHHHHHHHHHHHHCCCCEEECCCCCHHHHC
GSSAHQGVVGLGAARKYADLDSVAESEMLVVLDGVEDPHNLGAIVRTAHAAGAGAVIVPE
CCCCCCCEEECCCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCEEEECC
RRAAGVTDVVAKAAAGALEHLPVVRVTNINRALEDLKERGMWIYGLDERGTESYDQIDYA
HHHCCHHHHHHHHHHHHHHHCCEEEECCHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHC
KKSVLVLGGEGKGLHEQVRKHCDVLVRIPMAGQISSLNVSVAAGVVLFEWRRRRPVR
CCEEEEECCCCCCHHHHHHHHCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
ALLSGIHPVVEALRAGNPLERIVIAQGAGGPRLQEIIDLARQAKIPVRFEPRPSLDRLA
CHHHHHHHHHHHHHCCCCHHEEEEECCCCCHHHHHHHHHHHHCCCCEEECCCCCHHHHC
GSSAHQGVVGLGAARKYADLDSVAESEMLVVLDGVEDPHNLGAIVRTAHAAGAGAVIVPE
CCCCCCCEEECCCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCEEEECC
RRAAGVTDVVAKAAAGALEHLPVVRVTNINRALEDLKERGMWIYGLDERGTESYDQIDYA
HHHCCHHHHHHHHHHHHHHHCCEEEECCHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHC
KKSVLVLGGEGKGLHEQVRKHCDVLVRIPMAGQISSLNVSVAAGVVLFEWRRRRPVR
CCEEEEECCCCCCHHHHHHHHCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 7510287; 3145906 [H]