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The map label for this gene is asnC

Identifier: 116621920

GI number: 116621920

Start: 3554700

End: 3556085

Strand: Reverse

Name: asnC

Synonym: Acid_2805

Alternate gene names: 116621920

Gene position: 3556085-3554700 (Counterclockwise)

Preceding gene: 116621921

Following gene: 116621919

Centisome position: 35.68

GC content: 61.47

Gene sequence:

>1386_bases
ATGATTCAACCAGACAGTTACGTACGGAGCCTGCTGAAACGCTCCCCCGGAGAAAGCGTCACCGCCCGGGGCTGGGTCAA
GACCCGCCGCGACAGCAAGAACGTCCATTTTATTCAGCTCAACGACGGGTCGTCGCCGGTCGACCTTCAGGTCGTGCTCG
ACGCCGGAGTCGTGCCCGAAGACGTGGTCGCCAAAATCACCACCGGCGCGTGCATCAGCGTGGAAGGCGATCTCGTCGCT
TCCATGGGCAAGGGCCAGGCGGTCGAAATCAAGGCGCGCGCTCTCACTGTCCACGGCACTGCCGACCCCGAACACTATCC
GCTGCAGAAGAAAAAACACACGCTCGAAACGCTACGTGAGCTCGGCCACCTGCGCACCCGCTCCAACACCTTCGGCGCGG
TCTTCCGCGTACGCAACGCCCTCGCTTGCGCCATCCACAAATTCTTCCAGGATCGCGGCTTCATGTACGTACACACCCCC
GTGATTTCGGCGTCGGACGCCGAAGGCGCGGGCAGTATGTTCCAGGTCACCACGCTCGACCTGCAATCCCCCAAGCCGGC
CGATTTCACCGGGGATTTTTTCGGCAAGCACACTTACCTGACGGTCAGCGGACAGCTGGAGGCCGAGATCTTCGCCCACG
CCTTCGCCAACGTCTATACCTTCGGCCCTACCTTCCGCGCCGAAAACTCAAACACCCCGCGCCACCTCGCCGAGTTCTAC
ATGATCGAGCCCGAGATGGCCTTCTGCGATCTCAAGGACAATCAGGATCTCGCCGAAGCCTTCCTCAAGAGCCAGGTGGA
ATACGTGGTCAACGCCTGCGGCCCTGACCTTGATTTCCTCGCCAAATGGTACGACCCCGAACTCCGCAAGACGCTCGACG
GCCTCATGAACGCGAGCTTCGAACGCATCACCTACACCGAAGCCATCGACCTGCTCCAGAGGTCCGGCCGCTCGTTTGAA
TTCCCCACCCAGTGGGGTTCCGACATGCAGAGCGAACATGAGCGCTATCTCACCGAAGAGGTCTTCAATAAACCGGTGAT
CGTCACCGACTATCCGAAGGACATCAAGGCCTTCTATATGCGCGGCAACGACGACGGCAAGACCGTGGCCGCCATGGACG
TGCTCGCTCCGCGCATTGGAGAAATCATCGGCGGCAGCCAGCGCGAAGAGCGCCACGACGTCCTGCTGCAGCGCATCCGC
GAAATGGCCGCCCACGGCCTCCGCGAGGAGGCCTACTGGTGGTATCTCGACCTGCGACGCTTCGGAGGCGTGGAGCACGC
CGGCTTCGGCATGGGCTTTGAGCGCATGCTCATGTACCTCACCGGCATGAAAAACATCCGCGACGTAATTCCCTTCCCGC
GCACTCCGGGGAACGCCGAGTTCTAG

Upstream 100 bases:

>100_bases
TTGAACTCAAGGAGAAACCTGAGTTCGCCGCCAACCCGCTCGAAAGCGCAAGGCTCTCCTTCGAGCGCCTGGAAGCGCAG
TAACGAAGGCCACCATCCAG

Downstream 100 bases:

>100_bases
TCATGGCGGCGCCATCGGTCGAAAAACTGCCGCTGCGGCTGGTCTCGTTGGATGCCTTCCGCGGCGCGACCATCGCCCTC
ATGGTGCTCGTCAACAATGC

Product: asparaginyl-tRNA synthetase

Products: NA

Alternate protein names: Asparagine--tRNA ligase; AsnRS

Number of amino acids: Translated: 461; Mature: 461

Protein sequence:

>461_residues
MIQPDSYVRSLLKRSPGESVTARGWVKTRRDSKNVHFIQLNDGSSPVDLQVVLDAGVVPEDVVAKITTGACISVEGDLVA
SMGKGQAVEIKARALTVHGTADPEHYPLQKKKHTLETLRELGHLRTRSNTFGAVFRVRNALACAIHKFFQDRGFMYVHTP
VISASDAEGAGSMFQVTTLDLQSPKPADFTGDFFGKHTYLTVSGQLEAEIFAHAFANVYTFGPTFRAENSNTPRHLAEFY
MIEPEMAFCDLKDNQDLAEAFLKSQVEYVVNACGPDLDFLAKWYDPELRKTLDGLMNASFERITYTEAIDLLQRSGRSFE
FPTQWGSDMQSEHERYLTEEVFNKPVIVTDYPKDIKAFYMRGNDDGKTVAAMDVLAPRIGEIIGGSQREERHDVLLQRIR
EMAAHGLREEAYWWYLDLRRFGGVEHAGFGMGFERMLMYLTGMKNIRDVIPFPRTPGNAEF

Sequences:

>Translated_461_residues
MIQPDSYVRSLLKRSPGESVTARGWVKTRRDSKNVHFIQLNDGSSPVDLQVVLDAGVVPEDVVAKITTGACISVEGDLVA
SMGKGQAVEIKARALTVHGTADPEHYPLQKKKHTLETLRELGHLRTRSNTFGAVFRVRNALACAIHKFFQDRGFMYVHTP
VISASDAEGAGSMFQVTTLDLQSPKPADFTGDFFGKHTYLTVSGQLEAEIFAHAFANVYTFGPTFRAENSNTPRHLAEFY
MIEPEMAFCDLKDNQDLAEAFLKSQVEYVVNACGPDLDFLAKWYDPELRKTLDGLMNASFERITYTEAIDLLQRSGRSFE
FPTQWGSDMQSEHERYLTEEVFNKPVIVTDYPKDIKAFYMRGNDDGKTVAAMDVLAPRIGEIIGGSQREERHDVLLQRIR
EMAAHGLREEAYWWYLDLRRFGGVEHAGFGMGFERMLMYLTGMKNIRDVIPFPRTPGNAEF
>Mature_461_residues
MIQPDSYVRSLLKRSPGESVTARGWVKTRRDSKNVHFIQLNDGSSPVDLQVVLDAGVVPEDVVAKITTGACISVEGDLVA
SMGKGQAVEIKARALTVHGTADPEHYPLQKKKHTLETLRELGHLRTRSNTFGAVFRVRNALACAIHKFFQDRGFMYVHTP
VISASDAEGAGSMFQVTTLDLQSPKPADFTGDFFGKHTYLTVSGQLEAEIFAHAFANVYTFGPTFRAENSNTPRHLAEFY
MIEPEMAFCDLKDNQDLAEAFLKSQVEYVVNACGPDLDFLAKWYDPELRKTLDGLMNASFERITYTEAIDLLQRSGRSFE
FPTQWGSDMQSEHERYLTEEVFNKPVIVTDYPKDIKAFYMRGNDDGKTVAAMDVLAPRIGEIIGGSQREERHDVLLQRIR
EMAAHGLREEAYWWYLDLRRFGGVEHAGFGMGFERMLMYLTGMKNIRDVIPFPRTPGNAEF

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI226491502, Length=449, Percent_Identity=44.3207126948775, Blast_Score=399, Evalue=1e-111,
Organism=Homo sapiens, GI4758762, Length=463, Percent_Identity=28.7257019438445, Blast_Score=173, Evalue=3e-43,
Organism=Homo sapiens, GI45439306, Length=492, Percent_Identity=27.2357723577236, Blast_Score=122, Evalue=9e-28,
Organism=Escherichia coli, GI1787161, Length=451, Percent_Identity=55.6541019955654, Blast_Score=497, Evalue=1e-142,
Organism=Caenorhabditis elegans, GI17556372, Length=422, Percent_Identity=31.7535545023697, Blast_Score=189, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI71984122, Length=451, Percent_Identity=28.8248337028825, Blast_Score=182, Evalue=3e-46,
Organism=Caenorhabditis elegans, GI17551876, Length=493, Percent_Identity=25.3549695740365, Blast_Score=110, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6319872, Length=471, Percent_Identity=36.0934182590234, Blast_Score=288, Evalue=2e-78,
Organism=Saccharomyces cerevisiae, GI6321807, Length=460, Percent_Identity=29.3478260869565, Blast_Score=193, Evalue=6e-50,
Organism=Saccharomyces cerevisiae, GI6323011, Length=345, Percent_Identity=31.8840579710145, Blast_Score=130, Evalue=6e-31,
Organism=Drosophila melanogaster, GI19922416, Length=461, Percent_Identity=35.3579175704989, Blast_Score=254, Evalue=8e-68,
Organism=Drosophila melanogaster, GI19921528, Length=455, Percent_Identity=28.1318681318681, Blast_Score=168, Evalue=7e-42,
Organism=Drosophila melanogaster, GI17136276, Length=468, Percent_Identity=26.2820512820513, Blast_Score=112, Evalue=8e-25,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): SYN_SOLUE (Q023P9)

Other databases:

- EMBL:   CP000473
- RefSeq:   YP_824076.1
- ProteinModelPortal:   Q023P9
- SMR:   Q023P9
- STRING:   Q023P9
- GeneID:   4429026
- GenomeReviews:   CP000473_GR
- KEGG:   sus:Acid_2805
- NMPDR:   fig|234267.9.peg.2681
- eggNOG:   COG0017
- HOGENOM:   HBG745843
- OMA:   EPEMAFC
- PhylomeDB:   Q023P9
- ProtClustDB:   PRK03932
- GO:   GO:0005737
- HAMAP:   MF_00534
- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR004522
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365
- Gene3D:   G3DSA:2.40.50.140
- PANTHER:   PTHR22594
- PRINTS:   PR01042
- TIGRFAMs:   TIGR00457

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti; SSF50249 Nucleic_acid_OB

EC number: =6.1.1.22

Molecular weight: Translated: 51964; Mature: 51964

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQPDSYVRSLLKRSPGESVTARGWVKTRRDSKNVHFIQLNDGSSPVDLQVVLDAGVVPE
CCCCHHHHHHHHHCCCCCCCEECCHHHCCCCCCCEEEEEECCCCCCEEEEEEEECCCCCH
DVVAKITTGACISVEGDLVASMGKGQAVEIKARALTVHGTADPEHYPLQKKKHTLETLRE
HHHHHHCCCEEEEECCHHHHCCCCCCEEEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHH
LGHLRTRSNTFGAVFRVRNALACAIHKFFQDRGFMYVHTPVISASDAEGAGSMFQVTTLD
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCEEECCCCCCCCCEEEEEEEE
LQSPKPADFTGDFFGKHTYLTVSGQLEAEIFAHAFANVYTFGPTFRAENSNTPRHLAEFY
CCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHEECCCEEECCCCCCHHHHHHHH
MIEPEMAFCDLKDNQDLAEAFLKSQVEYVVNACGPDLDFLAKWYDPELRKTLDGLMNASF
EECCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHCCCH
ERITYTEAIDLLQRSGRSFEFPTQWGSDMQSEHERYLTEEVFNKPVIVTDYPKDIKAFYM
HHHHHHHHHHHHHHCCCCCCCCHHCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEEE
RGNDDGKTVAAMDVLAPRIGEIIGGSQREERHDVLLQRIREMAAHGLREEAYWWYLDLRR
ECCCCCCEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHH
FGGVEHAGFGMGFERMLMYLTGMKNIRDVIPFPRTPGNAEF
HCCCCCCCCCCCHHHHHHHHHCHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MIQPDSYVRSLLKRSPGESVTARGWVKTRRDSKNVHFIQLNDGSSPVDLQVVLDAGVVPE
CCCCHHHHHHHHHCCCCCCCEECCHHHCCCCCCCEEEEEECCCCCCEEEEEEEECCCCCH
DVVAKITTGACISVEGDLVASMGKGQAVEIKARALTVHGTADPEHYPLQKKKHTLETLRE
HHHHHHCCCEEEEECCHHHHCCCCCCEEEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHH
LGHLRTRSNTFGAVFRVRNALACAIHKFFQDRGFMYVHTPVISASDAEGAGSMFQVTTLD
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCEEECCCCCCCCCEEEEEEEE
LQSPKPADFTGDFFGKHTYLTVSGQLEAEIFAHAFANVYTFGPTFRAENSNTPRHLAEFY
CCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHEECCCEEECCCCCCHHHHHHHH
MIEPEMAFCDLKDNQDLAEAFLKSQVEYVVNACGPDLDFLAKWYDPELRKTLDGLMNASF
EECCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHCCCH
ERITYTEAIDLLQRSGRSFEFPTQWGSDMQSEHERYLTEEVFNKPVIVTDYPKDIKAFYM
HHHHHHHHHHHHHHCCCCCCCCHHCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEEE
RGNDDGKTVAAMDVLAPRIGEIIGGSQREERHDVLLQRIREMAAHGLREEAYWWYLDLRR
ECCCCCCEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHH
FGGVEHAGFGMGFERMLMYLTGMKNIRDVIPFPRTPGNAEF
HCCCCCCCCCCCHHHHHHHHHCHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA