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The map label for this gene is thrC [H]

Identifier: 116619681

GI number: 116619681

Start: 657907

End: 659130

Strand: Direct

Name: thrC [H]

Synonym: Acid_0546

Alternate gene names: 116619681

Gene position: 657907-659130 (Clockwise)

Preceding gene: 116619680

Following gene: 116619682

Centisome position: 6.6

GC content: 64.05

Gene sequence:

>1224_bases
ATGCCTAAAGCGACCCATCTGGAGTGCAGCCTTTGCGCGACGAAGTTCGACGCCGGGGCAGCCGCCAACCTCTGCGCGTG
CGGAGGCCCTTTGCTGGTCCGGTACGATCTGGCCACTATCCGACACCGCTGGCTGCGGCGCGAGGTCTCCAATGGCCCGG
CTACGATGTGGCGTTATGCGCCGGTGCTGCCGCCATCCGATGCTTCGGTGGTGACACTCGGCGAAGGCTGGACGCCGCTG
GTGCGCACCAAGCGCCTGGGTGCGCGGATCGGAGCTGATTCGCTCTGGGTCAAAGACGAAGGGCTCAACCCCACGGCGTC
GTTCAAAGCTCGCGGGCTCTCCTGCGCGGTATCGATGTGCGTGGAACTCGGAATCAAGAAGGTCGCAATTCCCTCCGCGG
GGAACGCGGCGAGCGCGATGGCGGCGTACGCGGCGGCCGCCGGCATTGAGGCTCACATTTTCATGCCGCGCGACGTTCCG
CAAGCCAATTACCTGGAGTGCAAGGCGTACGGCGCGCACGTCACGCTGATTGACGGGCTAATCAGCGATTGCGGCCGCAT
GGTTGCCGAACAAGGCCCCAAGGAAGGCTGGTTCGACGTTTCGACATTGAAGGAGCCATACCGCATCGAGGGCAAGAAGA
CGATGGGGTACGAGGTGGCGGAGCAGATGGGTTGGGAACTGCCGGAAGCGATTTTCTATCCGACCGGCGGCGGCGTGGGC
ATGATCGGCATGTGGAAGGCGTTCGACGAAATGGAAAGGCTGGGCTGGATCGGCGGACGGCGTCCCAAAATGATCGCGGT
GCAGGCGGAAGGCTGCCAGCCGGTGGTGCGTGCATTCGAAGCGGGCGAGCAGCGCAGCAAATTCTTCGAAGGCGCTCATA
CGGTGGCGAGCGGACTCCGCGTCCCCAAACCGCTCGGCGATTTTCTGGTGCTGAACGCGGTCCGGGAGAGCGGTGGTACG
GCCATCGCGGTGTGCGACGAAGATATGTTGACCGCCGGAGTGCACCTGGCCAGCGACGAGGGCATCTACGCGGCACCGGA
GGGCGCAGCCTGTGTGTGCGCCGCGCAACGCCTGCTGAAATCCGGATTCCTCAAGAGCACTGATCGCATGGTGATCTACA
ATACGGGATCGGGTTTGAAGTACCCCGAAGCGTATTCGACGCGATTCCCGCGGACGGCGGCGAGCGAGCAGGACAAACTA
GGCGGGCTGATCACGCCGCGGTAG

Upstream 100 bases:

>100_bases
TCACAGGACTTTTGCGCTTTTTCGGGGGGCATGGCGGAGCGGGCTGGTACTTTTGACGCGATTCGGCAGGCGTGGAGCCA
GATGTTAGACTTTCTACTGA

Downstream 100 bases:

>100_bases
TGAAGAATGGCACCGTCTCACGCCCCGGAACAGGTCGCGCGACGCCCCCGGCTGCAATGCCTGTTTTACGCCATTCTGGC
GGCCGGGCTCGGCCTGGCAT

Product: threonine synthase

Products: NA

Alternate protein names: TS [H]

Number of amino acids: Translated: 407; Mature: 406

Protein sequence:

>407_residues
MPKATHLECSLCATKFDAGAAANLCACGGPLLVRYDLATIRHRWLRREVSNGPATMWRYAPVLPPSDASVVTLGEGWTPL
VRTKRLGARIGADSLWVKDEGLNPTASFKARGLSCAVSMCVELGIKKVAIPSAGNAASAMAAYAAAAGIEAHIFMPRDVP
QANYLECKAYGAHVTLIDGLISDCGRMVAEQGPKEGWFDVSTLKEPYRIEGKKTMGYEVAEQMGWELPEAIFYPTGGGVG
MIGMWKAFDEMERLGWIGGRRPKMIAVQAEGCQPVVRAFEAGEQRSKFFEGAHTVASGLRVPKPLGDFLVLNAVRESGGT
AIAVCDEDMLTAGVHLASDEGIYAAPEGAACVCAAQRLLKSGFLKSTDRMVIYNTGSGLKYPEAYSTRFPRTAASEQDKL
GGLITPR

Sequences:

>Translated_407_residues
MPKATHLECSLCATKFDAGAAANLCACGGPLLVRYDLATIRHRWLRREVSNGPATMWRYAPVLPPSDASVVTLGEGWTPL
VRTKRLGARIGADSLWVKDEGLNPTASFKARGLSCAVSMCVELGIKKVAIPSAGNAASAMAAYAAAAGIEAHIFMPRDVP
QANYLECKAYGAHVTLIDGLISDCGRMVAEQGPKEGWFDVSTLKEPYRIEGKKTMGYEVAEQMGWELPEAIFYPTGGGVG
MIGMWKAFDEMERLGWIGGRRPKMIAVQAEGCQPVVRAFEAGEQRSKFFEGAHTVASGLRVPKPLGDFLVLNAVRESGGT
AIAVCDEDMLTAGVHLASDEGIYAAPEGAACVCAAQRLLKSGFLKSTDRMVIYNTGSGLKYPEAYSTRFPRTAASEQDKL
GGLITPR
>Mature_406_residues
PKATHLECSLCATKFDAGAAANLCACGGPLLVRYDLATIRHRWLRREVSNGPATMWRYAPVLPPSDASVVTLGEGWTPLV
RTKRLGARIGADSLWVKDEGLNPTASFKARGLSCAVSMCVELGIKKVAIPSAGNAASAMAAYAAAAGIEAHIFMPRDVPQ
ANYLECKAYGAHVTLIDGLISDCGRMVAEQGPKEGWFDVSTLKEPYRIEGKKTMGYEVAEQMGWELPEAIFYPTGGGVGM
IGMWKAFDEMERLGWIGGRRPKMIAVQAEGCQPVVRAFEAGEQRSKFFEGAHTVASGLRVPKPLGDFLVLNAVRESGGTA
IAVCDEDMLTAGVHLASDEGIYAAPEGAACVCAAQRLLKSGFLKSTDRMVIYNTGSGLKYPEAYSTRFPRTAASEQDKLG
GLITPR

Specific function: Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine [H]

COG id: COG0498

COG function: function code E; Threonine synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR000634
- InterPro:   IPR004450 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.3.1 [H]

Molecular weight: Translated: 43588; Mature: 43456

Theoretical pI: Translated: 7.82; Mature: 7.82

Prosite motif: PS00165 DEHYDRATASE_SER_THR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKATHLECSLCATKFDAGAAANLCACGGPLLVRYDLATIRHRWLRREVSNGPATMWRYA
CCCCCCEEHHHHHHHCCCCCCCCHHHCCCCEEEEEHHHHHHHHHHHHHHCCCCCEEEEEC
PVLPPSDASVVTLGEGWTPLVRTKRLGARIGADSLWVKDEGLNPTASFKARGLSCAVSMC
CCCCCCCCCEEEECCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHCCHHHHHHHH
VELGIKKVAIPSAGNAASAMAAYAAAAGIEAHIFMPRDVPQANYLECKAYGAHVTLIDGL
HHHCCCEEECCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEEECCCEEHHHHHH
ISDCGRMVAEQGPKEGWFDVSTLKEPYRIEGKKTMGYEVAEQMGWELPEAIFYPTGGGVG
HHHHHHHHHHCCCCCCCEEHHHCCCCEEECCCCCCHHHHHHHCCCCCCCEEEECCCCCCC
MIGMWKAFDEMERLGWIGGRRPKMIAVQAEGCQPVVRAFEAGEQRSKFFEGAHTVASGLR
HHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHCCHHHHHHHHHHHHHHHCCC
VPKPLGDFLVLNAVRESGGTAIAVCDEDMLTAGVHLASDEGIYAAPEGAACVCAAQRLLK
CCCCCHHHHHHHHHHHCCCCEEEEECCCHHHHCEEEECCCCEEECCCCCHHHHHHHHHHH
SGFLKSTDRMVIYNTGSGLKYPEAYSTRFPRTAASEQDKLGGLITPR
HCCCCCCCCEEEEECCCCCCCCHHHHCCCCCCCCCCHHHCCCCCCCC
>Mature Secondary Structure 
PKATHLECSLCATKFDAGAAANLCACGGPLLVRYDLATIRHRWLRREVSNGPATMWRYA
CCCCCEEHHHHHHHCCCCCCCCHHHCCCCEEEEEHHHHHHHHHHHHHHCCCCCEEEEEC
PVLPPSDASVVTLGEGWTPLVRTKRLGARIGADSLWVKDEGLNPTASFKARGLSCAVSMC
CCCCCCCCCEEEECCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHCCHHHHHHHH
VELGIKKVAIPSAGNAASAMAAYAAAAGIEAHIFMPRDVPQANYLECKAYGAHVTLIDGL
HHHCCCEEECCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEEECCCEEHHHHHH
ISDCGRMVAEQGPKEGWFDVSTLKEPYRIEGKKTMGYEVAEQMGWELPEAIFYPTGGGVG
HHHHHHHHHHCCCCCCCEEHHHCCCCEEECCCCCCHHHHHHHCCCCCCCEEEECCCCCCC
MIGMWKAFDEMERLGWIGGRRPKMIAVQAEGCQPVVRAFEAGEQRSKFFEGAHTVASGLR
HHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHCCHHHHHHHHHHHHHHHCCC
VPKPLGDFLVLNAVRESGGTAIAVCDEDMLTAGVHLASDEGIYAAPEGAACVCAAQRLLK
CCCCCHHHHHHHHHHHCCCCEEEEECCCHHHHCEEEECCCCEEECCCCCHHHHHHHHHHH
SGFLKSTDRMVIYNTGSGLKYPEAYSTRFPRTAASEQDKLGGLITPR
HCCCCCCCCEEEEECCCCCCCCHHHHCCCCCCCCCCHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]