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The map label for this gene is prsA

Identifier: 116517083

GI number: 116517083

Start: 882753

End: 883694

Strand: Direct

Name: prsA

Synonym: SPD_0868

Alternate gene names: 116517083

Gene position: 882753-883694 (Clockwise)

Preceding gene: 116516018

Following gene: 116516172

Centisome position: 43.14

GC content: 36.94

Gene sequence:

>942_bases
ATGAAGAAAAAATTATTGGCAGGTGCCATCACACTATTATCAGTAGCAACTTTAGCAGCTTGTTCGAAAGGGTCAGAAGG
AGCAGACCTTATCAGCATGAAAGGGGATGTCATCACAGAACATCAATTTTATGAGCAAGTGAAAAACAACCCTTCAGCCC
AACAAGTCTTGTTAAATATGACCATCCAAAAAGTTTTTGAAAAACAATATGGCTCAGAGCTTGATGATAAAGAGGTTGAT
GATACTATTGCCGAAGAAAAAAAACAATATGGCGAAAACTACCAACGTGTCTTGTCACAAGCAGGTATGACTCTTGAAAC
ACGTAAAGCTCAAATTCGTACAAGTAAATTAGTTGAGTTGGCAGTTAAGAAGGTAGCAGAAGCTGAATTGACAGATGAAG
CCTATAAGAAAGCCTTTGATGAGTACACTCCAGATGTAACGGCTCAAATCATCCGTCTTAATAATGAAGATAAGGCCAAA
GAAGTTCTCGAAAAAGCCAAGGCAGAAGGTGCTGATTTTGCTCAATTAGCCAAAGATAATTCAACTGATGAAAAAACAAA
AGAAAATGGTGGAGAAATTACCTTTGATTCTGCTTCAACAGAAGTACCTGAGCAAGTCAAAAAAGCCGCTTTCGCTTTAG
ATGTGGATGGTGTTTCTGATGTGATTACAGCAACTGGCACACAAGCCTACAGTAGCCAATATTACATTGTAAAACTCACT
AAGAAAACAGAAAAATCATCTAATATTGATGACTACAAAGAAAAATTAAAAACTGTTATCTTGACTCAAAAACAAAATGA
TTCAACATTTGTTCAAAGCATTATCGGAAAAGAATTGCAAGCAGCCAATATCAAGGTTAAGGACCAAGCCTTCCAAAATA
TCTTTACCCAATATATCGGTGGTGGAGATTCAAGCTCAAGCAGTAGTACATCAAACGAATAG

Upstream 100 bases:

>100_bases
TGTAGCAGATGTTCAACTGTCTGAAAGCGAATGATTTTCAGAAAAATTTAAGAAAAAATAGTAAAATAGATAGAGTAACA
CTTATCTCAAAGGAGTAGAC

Downstream 100 bases:

>100_bases
TCCAAATCAATGAGTCAGGGAAAAAACTCGACTTCAGGAAAAAATGAAGCAAACATTCCCACAATAAAACGCATAGTACA
AGGTTTGTACTGCCCCCCAA

Product: foldase protein PrsA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFYEQVKNNPSAQQVLLNMTIQKVFEKQYGSELDDKEVD
DTIAEEKKQYGENYQRVLSQAGMTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGVSDVITATGTQAYSSQYYIVKLT
KKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIGKELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE

Sequences:

>Translated_313_residues
MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFYEQVKNNPSAQQVLLNMTIQKVFEKQYGSELDDKEVD
DTIAEEKKQYGENYQRVLSQAGMTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGVSDVITATGTQAYSSQYYIVKLT
KKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIGKELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE
>Mature_313_residues
MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFYEQVKNNPSAQQVLLNMTIQKVFEKQYGSELDDKEVD
DTIAEEKKQYGENYQRVLSQAGMTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGVSDVITATGTQAYSSQYYIVKLT
KKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIGKELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE

Specific function: Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRSA_STRP2 (Q04KU8)

Other databases:

- EMBL:   CP000410
- RefSeq:   YP_816350.1
- ProteinModelPortal:   Q04KU8
- SMR:   Q04KU8
- STRING:   Q04KU8
- PhosSite:   Q04KU8
- EnsemblBacteria:   EBSTRT00000019711
- GeneID:   4441933
- GenomeReviews:   CP000410_GR
- KEGG:   spd:SPD_0868
- eggNOG:   COG0760
- GeneTree:   EBGT00050000028078
- HOGENOM:   HBG712792
- OMA:   MLVEYAV
- ProtClustDB:   PRK01326
- HAMAP:   MF_01145
- InterPro:   IPR023059
- InterPro:   IPR000297

Pfam domain/function: PF00639 Rotamase

EC number: =5.2.1.8

Molecular weight: Translated: 34440; Mature: 34440

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS01096 PPIC_PPIASE_1; PS50198 PPIC_PPIASE_2; PS51257 PROKAR_LIPOPROTEIN; PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFYEQVKNNPSAQQVLLNM
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHHHCCCHHHHHHHHH
TIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAGMTLETRKAQIRTSKLVEL
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHH
AVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAKEVLEKAKAEGADFAQLAKDN
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHCCC
STDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGVSDVITATGTQAYSSQYYIVKLT
CCCHHHHHCCCEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHCCCEEEEEEE
KKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIGKELQAANIKVKDQAFQNIFTQYIG
CCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHC
GGDSSSSSSTSNE
CCCCCCCCCCCCC
>Mature Secondary Structure
MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFYEQVKNNPSAQQVLLNM
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHHHCCCHHHHHHHHH
TIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAGMTLETRKAQIRTSKLVEL
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHH
AVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAKEVLEKAKAEGADFAQLAKDN
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHCCC
STDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGVSDVITATGTQAYSSQYYIVKLT
CCCHHHHHCCCEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHCCCEEEEEEE
KKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIGKELQAANIKVKDQAFQNIFTQYIG
CCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHC
GGDSSSSSSTSNE
CCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA