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The map label for this gene is sun [H]

Identifier: 116517030

GI number: 116517030

Start: 1566366

End: 1567679

Strand: Reverse

Name: sun [H]

Synonym: SPD_1544

Alternate gene names: 116517030

Gene position: 1567679-1566366 (Counterclockwise)

Preceding gene: 116515769

Following gene: 116515932

Centisome position: 76.62

GC content: 44.37

Gene sequence:

>1314_bases
GTGACTAAAGTAGAAACGGCTAGAAGTTTAGCTCTAGCAGTGCTAGAGGATGTTTTTGTGAACCAAGCATATTCAAATAT
CGCCTTAAATAAACACCTCAAGGGGAGTCAGCTCTCTGCAGCAGACAAGGGCTTAGTGACCGAGCTAGTCTATGGAACGG
TAGCCCGTAAACTGACTCTGGAATGGTACCTATCCCACTTTATCGAAGACAGAGACCAGTTAGACAGCTGGCTCTATGTC
CTTCTTCTCATGAGTGCCTACCAACTCCGCTATTTGGACAAGATTCCAGATCATGCTGTGGTCAATGAAGCAGTGGAATT
GGCCAAACTCCGTAAAAAAGGCAGTGAAAAATTGGTCAACGCTGTCCTTCGCCGTATCTTGCGTGAAGACTGGCCAGATA
TTGCTAGCATCAAGCGAAAAAACAAGCGTGACTCCATTGCCTATTCTCTCCCAGTTTGGCTAGTTGCCAAACTCAAGGAA
GAATACGGAGAGGAGAGAGCAAAAGCCATCTTTGAAAGCCTGTTAGTGCGAAACAAAGCCAGTATTCGTGTAACAGACCT
AAGTCGAAAAGAGGAAATCCAAGCCTTGTTGGAGGCGAATAATTCCCTTTTAGCAACCACTGGTCTGGTTAAGGAGCAGG
GGCATTTTGCAGGGCATAATTTGTTTGCGGATGGAGCCATTACCATCCAAGATGAGTCCAGTCAGCTGGTTGCTCCGACG
CTTGATTTACAAGGTGATGAGCGAGTGCTTGATGCCTGTGCGGCTCCAGGTGGGAAAACAGCCCATATAGCCTCTTATCT
TACGACAGGTCAGGTTACTGCTCTGGACTTGTACGACCACAAGTTGGATTTAATTCAAGAAAATGCCCAACGTCTGGGAG
TTGAAGATCGGGTTCAAACTCAAAAATTGGATGCCAGAAAGGTGCATGAGTTTTTTGACCAGGATTCCTTTGATAAGATT
TTGGTGGATGCTCCTTGTTCAGGAATCGGTCTTTTGCGCCGAAAACCAGATATCAAATACAATAAAGAAACGGCAGATTT
CGCGTCCTTGCAGGAAATTCAGTTAGAAATATTAGGTAGTGTTTGTCAAATACTAGGCAAAGGTGGTATAATAACTTATA
GCACCTGCACTATCGTCTCAGAGGAGAATTTTCAAGTCGTTAAGGCCTTTTTAGAGAGTCATCCCGAGTTCGAGCAGGTA
AAACTAGAACATGAATGTAAGGATATCATGAAAGACGGCTGTATCCTCATTACACCTGAATTGTATGGAAGTGATGGATT
CTTCATCAGTCAATTTCGCAAGATATCGGATTAG

Upstream 100 bases:

>100_bases
CTATCCCTCAAACAAGTGCAGCCAGCTGGTAAGCCTAAGATGGACATTGCTTCCTTCCTCAACGGAGTTGGACGTACATT
GACTGTAGGAGAACGATTTG

Downstream 100 bases:

>100_bases
GAAGGAACTGACACATGGAAATTTCATTATTAACAGATGTTGGTCAGAAACGAACAAATAACCAAGACTATGTCAACCAC
TATGTCAATAGAGCTGGACG

Product: ribosomal RNA small subunit methyltransferase B

Products: NA

Alternate protein names: rRNA (cytosine-C(5)-)-methyltransferase rsmB [H]

Number of amino acids: Translated: 437; Mature: 436

Protein sequence:

>437_residues
MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLSAADKGLVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYV
LLLMSAYQLRYLDKIPDHAVVNEAVELAKLRKKGSEKLVNAVLRRILREDWPDIASIKRKNKRDSIAYSLPVWLVAKLKE
EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANNSLLATTGLVKEQGHFAGHNLFADGAITIQDESSQLVAPT
LDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALDLYDHKLDLIQENAQRLGVEDRVQTQKLDARKVHEFFDQDSFDKI
LVDAPCSGIGLLRRKPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLESHPEFEQV
KLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD

Sequences:

>Translated_437_residues
MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLSAADKGLVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYV
LLLMSAYQLRYLDKIPDHAVVNEAVELAKLRKKGSEKLVNAVLRRILREDWPDIASIKRKNKRDSIAYSLPVWLVAKLKE
EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANNSLLATTGLVKEQGHFAGHNLFADGAITIQDESSQLVAPT
LDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALDLYDHKLDLIQENAQRLGVEDRVQTQKLDARKVHEFFDQDSFDKI
LVDAPCSGIGLLRRKPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLESHPEFEQV
KLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD
>Mature_436_residues
TKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLSAADKGLVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVL
LLMSAYQLRYLDKIPDHAVVNEAVELAKLRKKGSEKLVNAVLRRILREDWPDIASIKRKNKRDSIAYSLPVWLVAKLKEE
YGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANNSLLATTGLVKEQGHFAGHNLFADGAITIQDESSQLVAPTL
DLQGDERVLDACAAPGGKTAHIASYLTTGQVTALDLYDHKLDLIQENAQRLGVEDRVQTQKLDARKVHEFFDQDSFDKIL
VDAPCSGIGLLRRKPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLESHPEFEQVK
LEHECKDIMKDGCILITPELYGSDGFFISQFRKISD

Specific function: Unknown

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI32698918, Length=223, Percent_Identity=34.9775784753363, Blast_Score=109, Evalue=5e-24,
Organism=Homo sapiens, GI76150625, Length=333, Percent_Identity=29.7297297297297, Blast_Score=109, Evalue=6e-24,
Organism=Homo sapiens, GI76150623, Length=333, Percent_Identity=29.7297297297297, Blast_Score=109, Evalue=6e-24,
Organism=Homo sapiens, GI23199998, Length=239, Percent_Identity=28.8702928870293, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI270288816, Length=239, Percent_Identity=28.8702928870293, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI8922322, Length=239, Percent_Identity=28.8702928870293, Blast_Score=80, Evalue=6e-15,
Organism=Homo sapiens, GI270288818, Length=239, Percent_Identity=28.8702928870293, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI11545785, Length=168, Percent_Identity=31.547619047619, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI39995082, Length=188, Percent_Identity=29.7872340425532, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI301336155, Length=188, Percent_Identity=29.7872340425532, Blast_Score=73, Evalue=5e-13,
Organism=Escherichia coli, GI2367212, Length=453, Percent_Identity=31.5673289183223, Blast_Score=186, Evalue=3e-48,
Organism=Escherichia coli, GI87081985, Length=218, Percent_Identity=32.1100917431193, Blast_Score=107, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17536757, Length=239, Percent_Identity=31.3807531380753, Blast_Score=99, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI71998419, Length=241, Percent_Identity=29.8755186721992, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI115534021, Length=241, Percent_Identity=29.8755186721992, Blast_Score=79, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6324268, Length=312, Percent_Identity=28.525641025641, Blast_Score=102, Evalue=9e-23,
Organism=Saccharomyces cerevisiae, GI6319447, Length=198, Percent_Identity=28.2828282828283, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6324306, Length=276, Percent_Identity=25.3623188405797, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI22024126, Length=244, Percent_Identity=30.327868852459, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI24668781, Length=271, Percent_Identity=30.2583025830258, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI21356513, Length=238, Percent_Identity=31.9327731092437, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI21355201, Length=189, Percent_Identity=32.2751322751323, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI21356579, Length=241, Percent_Identity=26.9709543568465, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI19920494, Length=188, Percent_Identity=29.2553191489362, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: NA

Molecular weight: Translated: 49058; Mature: 48926

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: PS01153 NOL1_NOP2_SUN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLSAADKGLVTELVYGTVARKLTL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
EWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVNEAVELAKLRKKGSEKLVN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHH
AVLRRILREDWPDIASIKRKNKRDSIAYSLPVWLVAKLKEEYGEERAKAIFESLLVRNKA
HHHHHHHHHCCCCHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SIRVTDLSRKEEIQALLEANNSLLATTGLVKEQGHFAGHNLFADGAITIQDESSQLVAPT
CEEEECCCHHHHHHHHHHCCCCEEEECCHHHHCCCCCCCCEEECCEEEEECCCCCEEEEE
LDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALDLYDHKLDLIQENAQRLGVEDRVQT
CCCCCCHHHHHHHCCCCCCHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHCCCHHHHHH
QKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRRKPDIKYNKETADFASLQEIQLEILGS
HHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHH
VCQILGKGGIITYSTCTIVSEENFQVVKAFLESHPEFEQVKLEHECKDIMKDGCILITPE
HHHHHCCCCEEEEEEEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEECH
LYGSDGFFISQFRKISD
HCCCCCHHHHHHHHCCC
>Mature Secondary Structure 
TKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLSAADKGLVTELVYGTVARKLTL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
EWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVNEAVELAKLRKKGSEKLVN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHH
AVLRRILREDWPDIASIKRKNKRDSIAYSLPVWLVAKLKEEYGEERAKAIFESLLVRNKA
HHHHHHHHHCCCCHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SIRVTDLSRKEEIQALLEANNSLLATTGLVKEQGHFAGHNLFADGAITIQDESSQLVAPT
CEEEECCCHHHHHHHHHHCCCCEEEECCHHHHCCCCCCCCEEECCEEEEECCCCCEEEEE
LDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALDLYDHKLDLIQENAQRLGVEDRVQT
CCCCCCHHHHHHHCCCCCCHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHCCCHHHHHH
QKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRRKPDIKYNKETADFASLQEIQLEILGS
HHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHH
VCQILGKGGIITYSTCTIVSEENFQVVKAFLESHPEFEQVKLEHECKDIMKDGCILITPE
HHHHHCCCCEEEEEEEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEECH
LYGSDGFFISQFRKISD
HCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377; 9086272 [H]