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The map label for this gene is cps2D [H]

Identifier: 116517023

GI number: 116517023

Start: 316633

End: 317313

Strand: Direct

Name: cps2D [H]

Synonym: SPD_0318

Alternate gene names: 116517023

Gene position: 316633-317313 (Clockwise)

Preceding gene: 116517039

Following gene: 116516773

Centisome position: 15.47

GC content: 39.06

Gene sequence:

>681_bases
ATGCCAACGTTAGAAATCTCACAGGCAAAATTGGATTTTGTAAAAAAGGCAGAGGAATATTATAACTCTTTGTGCACGAA
CCTACAGTTAAGTGGAGATGGTTTGAAAGTATTTTCTATCACTTCTGTGAAACTAGGAGAAGGAAAATCAACGACTTCCA
CCAATATCGCTTGGGCTTTTGCGCGTGCAGGTTACAAAACGCTGCTGATTGATGGAGATATTCGCAATTCTGTTATGTTA
GGTGTCTTTAAAGCAAGGGATAAGATTACAGGCCTGACAGAATTTTTATCAGGAACTACAGACCTATCACAAGGGCTTTG
TGATACCAATATCGAAAATCTCTTTGTAATTCAGGCTGGCTCTGTGTCACCGAATCCGACAGCTCTTCTTCAAAGGAAGA
ATTTCAGTACAATGCTTGAAACCTTGCGTAAATATTTTGATTACATCATTGTAGATACAGCTCCTGTCGGTGTCGTGATT
GATGCGGCTATTATTACGCGAAAATGCGATGCTTCTATTTTAGTGACGGAGGCAGGTGAAATAAATCGACGGGATATTCA
AAAAGCAAAAGAACAGTTGGAACACACAGGGAAGCCGTTTTTGGGAGTTGTGTTGAATAAATTCGATACTTCAGTAGACA
AATACGGTTCTTATGGAGATTACGGGAAAAATAAAAAATAG

Upstream 100 bases:

>100_bases
CGACACCCGTGTGAAACGTCCTGAAGATATTGAAGATGTACTGCAAATTCCACTTTTAGGGCTCGTTCCAGATTTGGACA
AAATGAAATAGGAGGAAGTT

Downstream 100 bases:

>100_bases
GTCGGGGGATAGAGATGAATGGAAAAACAGTAAAGTCTTCATTGGCCATAATCCAGAGTTTTCTTATTATTTTATTGACT
TATCTACTTAGTGCTGTGAG

Product: tyrosine-protein kinase Cps2D cytosolic ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 225

Protein sequence:

>226_residues
MPTLEISQAKLDFVKKAEEYYNSLCTNLQLSGDGLKVFSITSVKLGEGKSTTSTNIAWAFARAGYKTLLIDGDIRNSVML
GVFKARDKITGLTEFLSGTTDLSQGLCDTNIENLFVIQAGSVSPNPTALLQRKNFSTMLETLRKYFDYIIVDTAPVGVVI
DAAIITRKCDASILVTEAGEINRRDIQKAKEQLEHTGKPFLGVVLNKFDTSVDKYGSYGDYGKNKK

Sequences:

>Translated_226_residues
MPTLEISQAKLDFVKKAEEYYNSLCTNLQLSGDGLKVFSITSVKLGEGKSTTSTNIAWAFARAGYKTLLIDGDIRNSVML
GVFKARDKITGLTEFLSGTTDLSQGLCDTNIENLFVIQAGSVSPNPTALLQRKNFSTMLETLRKYFDYIIVDTAPVGVVI
DAAIITRKCDASILVTEAGEINRRDIQKAKEQLEHTGKPFLGVVLNKFDTSVDKYGSYGDYGKNKK
>Mature_225_residues
PTLEISQAKLDFVKKAEEYYNSLCTNLQLSGDGLKVFSITSVKLGEGKSTTSTNIAWAFARAGYKTLLIDGDIRNSVMLG
VFKARDKITGLTEFLSGTTDLSQGLCDTNIENLFVIQAGSVSPNPTALLQRKNFSTMLETLRKYFDYIIVDTAPVGVVID
AAIITRKCDASILVTEAGEINRRDIQKAKEQLEHTGKPFLGVVLNKFDTSVDKYGSYGDYGKNKK

Specific function: Involved in the regulation of capsular polysaccharide biosynthesis. Autophosphorylation of CpsD attenuates its activity and reduces the level of encapsulation. May be part of a complex that directs the coordinated polymerization and export to the cell sur

COG id: COG0489

COG function: function code D; ATPases involved in chromosome partitioning

Gene ontology:

Cell location: Inner membrane (Probable) [C]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CpsD/CapB family [H]

Homologues:

Organism=Escherichia coli, GI87082032, Length=188, Percent_Identity=29.2553191489362, Blast_Score=94, Evalue=6e-21,
Organism=Escherichia coli, GI1787216, Length=170, Percent_Identity=31.1764705882353, Blast_Score=90, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR005702 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: =2.7.10.2 [H]

Molecular weight: Translated: 24828; Mature: 24696

Theoretical pI: Translated: 8.42; Mature: 8.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTLEISQAKLDFVKKAEEYYNSLCTNLQLSGDGLKVFSITSVKLGEGKSTTSTNIAWAF
CCCCCCHHHHHHHHHHHHHHHHHHHCCEEECCCCEEEEEEEEEEECCCCCCCCCHHEEEE
ARAGYKTLLIDGDIRNSVMLGVFKARDKITGLTEFLSGTTDLSQGLCDTNIENLFVIQAG
HHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCEEEEEEEC
SVSPNPTALLQRKNFSTMLETLRKYFDYIIVDTAPVGVVIDAAIITRKCDASILVTEAGE
CCCCCCHHEEECCCHHHHHHHHHHHHCEEEECCCCCCCEEHHHHHHHCCCCEEEEECCCC
INRRDIQKAKEQLEHTGKPFLGVVLNKFDTSVDKYGSYGDYGKNKK
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHCCCCCCCCCCCC
>Mature Secondary Structure 
PTLEISQAKLDFVKKAEEYYNSLCTNLQLSGDGLKVFSITSVKLGEGKSTTSTNIAWAF
CCCCCHHHHHHHHHHHHHHHHHHHCCEEECCCCEEEEEEEEEEECCCCCCCCCHHEEEE
ARAGYKTLLIDGDIRNSVMLGVFKARDKITGLTEFLSGTTDLSQGLCDTNIENLFVIQAG
HHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCEEEEEEEC
SVSPNPTALLQRKNFSTMLETLRKYFDYIIVDTAPVGVVIDAAIITRKCDASILVTEAGE
CCCCCCHHEEECCCHHHHHHHHHHHHCEEEECCCCCCCEEHHHHHHHCCCCEEEEECCCC
INRRDIQKAKEQLEHTGKPFLGVVLNKFDTSVDKYGSYGDYGKNKK
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11179285; 11463916 [H]