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The map label for this gene is ktrB [H]

Identifier: 116516800

GI number: 116516800

Start: 76686

End: 78065

Strand: Direct

Name: ktrB [H]

Synonym: SPD_0076

Alternate gene names: 116516800

Gene position: 76686-78065 (Clockwise)

Preceding gene: 116516250

Following gene: 116515848

Centisome position: 3.75

GC content: 41.45

Gene sequence:

>1380_bases
ATGTTATTCAAATTATCTAAGGAAAAAATAGAGCTAGGCTTATCTCGTTTATCGCCAGCCCGTCGTATTTTTTTGAGTTT
TGCCTTGGTCATTTTACTAGGCTCTCTTCTTTTGAGCTTGCCCTTTGTCCAAGTTGAAAGCTCACGAGCGACTTATTTTG
ATCATCTTTTCACTGCTGTCTCTGCAGTCTGTGTGACAGGTCTCTCAACCCTTCCAGTAGCTCACACCTATAATATCTGG
GGCCAAATAATCTGTTTGCTCTTGATTCAGATCGGTGGTCTAGGGCTCATGACTTTTATTGGGGTTTTCTATATCCAGAG
CAAGCAAAAGCTTAGTCTTCGTAGCCGTGCAACTATTCAGGATAGTTTTAGTTATGGAGAAACTCGATCTTTGAGAAAGT
TTGTCTATTCTATTTTTCTCACGACCTTTTTGGTTGAGAGCTTGGGAGCTATTTTGCTTAGTTTTCGCCTTATTCCTCAA
CTTGGCTGGGGACGTGGTCTTTTTAGTTCCATTTTTCTAGCGATCTCAGCCTTCTGTAATGCCGGTTTTGATAATTTAGG
GAGCACCAGTTTATTTGCTTTTCAGACCGATTTACTGGTCAATCTGGTGATTGCAGGCTTGATTATTACAGGCGGCCTTG
GTTTTATGGTCTGGTTTGATTTGGCTGGTCATGTAGGAAGAAAGAAAAAAGGACGTCTGCACTTTCATACGAAGCTTGTA
CTATTATTGACTATAGGTTTGTTGTTATTTGGAACAGCAACTACTCTCTTTCTTGAGTGGAACAATGCTGGAACGATTGG
CAATCTCCCTGTTGCCGATAAGGTTTTAGTTAGCTTTTTTCAAACAGTGACGATGCGAACAGCTGGCTTTTCTACGATAG
ATTATACTCAGGCTCATCCTGTGACTCTTTTGATTTATATCTTACAGATGTTTCTAGGTGGGGCACCTGGAGGAACAGCT
GGGGGACTCAAGATTACGACATTTTTTGTCCTCTTGGTCTTTGCACGAAGTGAGCTTCTAGGCTTGCCTCATGCCAATGT
TGCGAGACGAACGATCGCGCCGCGAACGGTTCAAAAATCCTTTAGTGTCTTTATTATCTTTTTGATGAGCTTCTTGATAG
GATTGATTCTGCTAGGGATAACAGCCAAAGGCAATCCTCCCTTTATCCACCTCGTATTTGAAACCATTTCAGCTCTTAGT
ACAGTTGGTGTAACGGCAAATCTGACTCCTGACCTTGGGAAATTGGCTCTCAGTGTTATCATGCCACTTATGTTTATGGG
ACGAATTGGTCCCTTGACCTTGTTTGTTAGCTTGGCAGATTACCATCCAGAAAAGAAAGATATGATTCACTATATGAAAG
CAGATATTAGTATTGGTTAA

Upstream 100 bases:

>100_bases
AAGCTATCAATAAAAAGGTGGCATTTTTTAGGCTTGGTGTTAGTGAATTTTGCCTTATCCTATCTAAGTCATTTCGAGCT
TTTTATGGTACAATGGAAAC

Downstream 100 bases:

>100_bases
GAAAGGAAAGAGCATGTCAGATCGTACGATTGGAATTTTGGGCTTGGGAATTTTTGGGAGCAGTGTCCTAGCTGCCCTAG
CCAAGCAGGATATGAATATT

Product: potassium uptake protein, Trk family protein

Products: Proton [Cytoplasm]; K (I) [Cytoplasm] [C]

Alternate protein names: K(+)-uptake protein ktrB [H]

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQVESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIW
GQIICLLLIQIGGLGLMTFIGVFYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVWFDLAGHVGRKKKGRLHFHTKLV
LLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVLVSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTA
GGLKITTFFVLLVFARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLVFETISALS
TVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIHYMKADISIG

Sequences:

>Translated_459_residues
MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQVESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIW
GQIICLLLIQIGGLGLMTFIGVFYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVWFDLAGHVGRKKKGRLHFHTKLV
LLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVLVSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTA
GGLKITTFFVLLVFARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLVFETISALS
TVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIHYMKADISIG
>Mature_459_residues
MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQVESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIW
GQIICLLLIQIGGLGLMTFIGVFYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVWFDLAGHVGRKKKGRLHFHTKLV
LLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVLVSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTA
GGLKITTFFVLLVFARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLVFETISALS
TVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIHYMKADISIG

Specific function: Integral membrane subunit of the KtrAB potassium uptake transporter. The 2 major potassium transporter complexes KtrAB and KtrCD confer resistance to both suddenly imposed and prolonged osmotic stress [H]

COG id: COG0168

COG function: function code P; Trk-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trkH potassium transport family. Ktr (TC 2.A.38.4) subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003445
- InterPro:   IPR004772 [H]

Pfam domain/function: PF02386 TrkH [H]

EC number: NA

Molecular weight: Translated: 50166; Mature: 50166

Theoretical pI: Translated: 10.46; Mature: 10.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure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HHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Periplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Periplasm] = Proton [Cytoplasm] + K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]