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The map label for this gene is licA [H]

Identifier: 116516692

GI number: 116516692

Start: 220444

End: 220764

Strand: Direct

Name: licA [H]

Synonym: SPD_0232

Alternate gene names: 116516692

Gene position: 220444-220764 (Clockwise)

Preceding gene: 116517202

Following gene: 116515458

Centisome position: 10.77

GC content: 32.4

Gene sequence:

>321_bases
ATGGAAATGATTGTTCCAGATCAAATTATCATGGGTTTAATTTTATATGCTGGCGATGCGAAACAACATATTTATAAAGC
ATTAGATTACATAAAGAACGGTACATGTGAACGATGTGAAGAAGAAATCCAGTTAGCTGATGCAGCCTTATTAGAAGCTC
ATAATCTACAAACAAAATTCTTGGCACAGGAAGCGTCTGGTACAAAGACAGAAATTACAGCTCTCTTTGTTCATTCACAA
GATCATCTCATGACTAGTATGACGGAGATTAATTTAATCAAAGAAATTATTAGTTTGAGAAAAGAACTTCATAAAAAATA
A

Upstream 100 bases:

>100_bases
TTGACAACTTTATTATGTAGTTGTATTCTATAGTTACAAAAGAAAATTTTAAAATTTCAAATGAAAAAAGCTTTTTACAT
AGTGAAATGAGGAGGAATTT

Downstream 100 bases:

>100_bases
TACTAGAGTATTATCATTGTTATTAACATAGAGGAGGAAAACATAATGGTGAAGATTGGTTTGTTTTGTGCAGCAGGTTT
TTCTACTGGTATGCTTGTAA

Product: PTS system, IIA component

Products: protein histidine; sugar phosphate

Alternate protein names: EIIA-Lic; EIII-Lic; PTS system lichenan-specific EIIA component [H]

Number of amino acids: Translated: 106; Mature: 106

Protein sequence:

>106_residues
MEMIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQLADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQ
DHLMTSMTEINLIKEIISLRKELHKK

Sequences:

>Translated_106_residues
MEMIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQLADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQ
DHLMTSMTEINLIKEIISLRKELHKK
>Mature_106_residues
MEMIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQLADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQ
DHLMTSMTEINLIKEIISLRKELHKK

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: COG1447

COG function: function code G; Phosphotransferase system cellobiose-specific component IIA

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIA type-3 domain [H]

Homologues:

Organism=Escherichia coli, GI1788031, Length=97, Percent_Identity=38.1443298969072, Blast_Score=67, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003188 [H]

Pfam domain/function: PF02255 PTS_IIA [H]

EC number: 2.7.1.69

Molecular weight: Translated: 12042; Mature: 12042

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: PS51095 PTS_EIIA_TYPE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEMIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQLADAALLEAHNLQTKF
CCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHH
LAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKELHKK
HHHHCCCCHHHHHEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEMIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQLADAALLEAHNLQTKF
CCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHH
LAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKELHKK
HHHHCCCCHHHHHEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: protein N(pi)-phosphohistidine; sugar

Specific reaction: protein N(pi)-phosphohistidine + sugar = protein histidine + sugar phosphate

General reaction: Transferring phosphorus-containing groups [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8990303; 8969509; 9384377 [H]