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The map label for this gene is nanM [H]

Identifier: 116516633

GI number: 116516633

Start: 1200079

End: 1201002

Strand: Reverse

Name: nanM [H]

Synonym: SPD_1171

Alternate gene names: 116516633

Gene position: 1201002-1200079 (Counterclockwise)

Preceding gene: 116516481

Following gene: 116515339

Centisome position: 58.7

GC content: 32.47

Gene sequence:

>924_bases
ATGAAAATTGATGTTATAAATCATTTAGACTCACCAGGATTAGCTGGGATGATTTGTAGACGGATTAATAATAGAATTTT
AGTTTATGGAGGTAGTTATTTCCCAAATAACGATCCTTTAAAAAGTTCAAAAGTTCAATCAAATAAAATTAGAGTTTATG
ATGAGAAATTTAATCTTCTATATGAACAAGATGGAAAAATTTCTCCAGATAAAGGAATAACGATTGAAGTTGAAAATGAA
ATCTATTACATTCTAGGCTCGAGCATTTATCGTATTACGATTGGTGAAAGTGTAGAAGAAACCTGTATCGGGAATTTTGA
TTTCCAACTAGAGAGTGGTTATGGTTGTTATTTTGATGGCCACTTATTCTTTGGATTTCAGGAAAGTTATTTGTTCAATA
TTGAGACTCAAGAGCTTTTTAAAAAATCTGACTTCCCAGTTTCTGGTAGAGGCCAAGGTTTGTCAGTCAAATATCAAAAT
GAATTGTATTATTTAGGTGGAGCGAACAATGAAGCTTATTTAGATGGATACAAATATAGTTTAAAAAAAGATAAGTGGGA
AAAACTTGAGTTCGAATTACCAAGCTCAGTTCTAGGAGCATCAAGTATACAAATAAATGAAAGTGGTTTATTAATACTTG
GTGGCTTTAATGAAATTGTTTATAATAAAGCAGTTATTGATTTAGCAACCCCTGGCTATAGGGAAGAATATTTTTCTAAA
GGGAGAGATTTCTTTAATTGGAATCGTAGCATGCGAATACTAGATTTAGAGACAGGTAAGGTCAAGATTATTGCAAACGA
TGAGCGTTTTGCTCTTTGTGGGGCAGGATTTTTAAAAACTGATAATGGATATTACGTTGTTAGTGGGGAATGTAGCCCAG
GAAGACGTACTTCTGACATACTTTTGTTAGAGGAGGAAATGTAA

Upstream 100 bases:

>100_bases
TGCGAGGCATCGTTGTTGGTGGCGCTATTACTAGACCAAAAGAGATTACAGAACGTTTTGTAGCGGGATTAAAATAGCAT
GCCAGAGTAAGAGGTGTAAT

Downstream 100 bases:

>100_bases
CGAAGAGTTTAAATTTTTAATTACTGCAATACTTACTTAATCACATAAATAATTACTTAATACAAATAAAGGAGTATTAA
AATGAAAAAAATTGTTAAAT

Product: hypothetical protein

Products: NA

Alternate protein names: N-acetylneuraminate mutarotase; Neu5Ac mutarotase; Sialic acid epimerase [H]

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MKIDVINHLDSPGLAGMICRRINNRILVYGGSYFPNNDPLKSSKVQSNKIRVYDEKFNLLYEQDGKISPDKGITIEVENE
IYYILGSSIYRITIGESVEETCIGNFDFQLESGYGCYFDGHLFFGFQESYLFNIETQELFKKSDFPVSGRGQGLSVKYQN
ELYYLGGANNEAYLDGYKYSLKKDKWEKLEFELPSSVLGASSIQINESGLLILGGFNEIVYNKAVIDLATPGYREEYFSK
GRDFFNWNRSMRILDLETGKVKIIANDERFALCGAGFLKTDNGYYVVSGECSPGRRTSDILLLEEEM

Sequences:

>Translated_307_residues
MKIDVINHLDSPGLAGMICRRINNRILVYGGSYFPNNDPLKSSKVQSNKIRVYDEKFNLLYEQDGKISPDKGITIEVENE
IYYILGSSIYRITIGESVEETCIGNFDFQLESGYGCYFDGHLFFGFQESYLFNIETQELFKKSDFPVSGRGQGLSVKYQN
ELYYLGGANNEAYLDGYKYSLKKDKWEKLEFELPSSVLGASSIQINESGLLILGGFNEIVYNKAVIDLATPGYREEYFSK
GRDFFNWNRSMRILDLETGKVKIIANDERFALCGAGFLKTDNGYYVVSGECSPGRRTSDILLLEEEM
>Mature_307_residues
MKIDVINHLDSPGLAGMICRRINNRILVYGGSYFPNNDPLKSSKVQSNKIRVYDEKFNLLYEQDGKISPDKGITIEVENE
IYYILGSSIYRITIGESVEETCIGNFDFQLESGYGCYFDGHLFFGFQESYLFNIETQELFKKSDFPVSGRGQGLSVKYQN
ELYYLGGANNEAYLDGYKYSLKKDKWEKLEFELPSSVLGASSIQINESGLLILGGFNEIVYNKAVIDLATPGYREEYFSK
GRDFFNWNRSMRILDLETGKVKIIANDERFALCGAGFLKTDNGYYVVSGECSPGRRTSDILLLEEEM

Specific function: Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, whic

COG id: COG3055

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 7 Kelch repeats [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015915
- InterPro:   IPR006652
- InterPro:   IPR019936 [H]

Pfam domain/function: PF01344 Kelch_1 [H]

EC number: NA

Molecular weight: Translated: 34908; Mature: 34908

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIDVINHLDSPGLAGMICRRINNRILVYGGSYFPNNDPLKSSKVQSNKIRVYDEKFNLL
CEEEEECCCCCCCHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEECCEEEE
YEQDGKISPDKGITIEVENEIYYILGSSIYRITIGESVEETCIGNFDFQLESGYGCYFDG
EECCCCCCCCCCEEEEECCEEEEEECCEEEEEEECCCCHHHHCCCEEEEEECCEEEEECC
HLFFGFQESYLFNIETQELFKKSDFPVSGRGQGLSVKYQNELYYLGGANNEAYLDGYKYS
EEEEEECCEEEEECCHHHHHHHCCCCCCCCCCEEEEEECCEEEEEECCCCCEEECCEEEE
LKKDKWEKLEFELPSSVLGASSIQINESGLLILGGFNEIVYNKAVIDLATPGYREEYFSK
CCCCCCEEEEEECCHHHHCCCEEEECCCCEEEEECCHHHHEEEEEEEECCCCHHHHHHHC
GRDFFNWNRSMRILDLETGKVKIIANDERFALCGAGFLKTDNGYYVVSGECSPGRRTSDI
CCCEEECCCEEEEEEECCCEEEEEECCCEEEEEECCEEEECCCEEEEECCCCCCCCCCEE
LLLEEEM
EEEEECC
>Mature Secondary Structure
MKIDVINHLDSPGLAGMICRRINNRILVYGGSYFPNNDPLKSSKVQSNKIRVYDEKFNLL
CEEEEECCCCCCCHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEECCEEEE
YEQDGKISPDKGITIEVENEIYYILGSSIYRITIGESVEETCIGNFDFQLESGYGCYFDG
EECCCCCCCCCCEEEEECCEEEEEECCEEEEEEECCCCHHHHCCCEEEEEECCEEEEECC
HLFFGFQESYLFNIETQELFKKSDFPVSGRGQGLSVKYQNELYYLGGANNEAYLDGYKYS
EEEEEECCEEEEECCHHHHHHHCCCCCCCCCCEEEEEECCEEEEEECCCCCEEECCEEEE
LKKDKWEKLEFELPSSVLGASSIQINESGLLILGGFNEIVYNKAVIDLATPGYREEYFSK
CCCCCCEEEEEECCHHHHCCCEEEECCCCEEEEECCHHHHEEEEEEEECCCCHHHHHHHC
GRDFFNWNRSMRILDLETGKVKIIANDERFALCGAGFLKTDNGYYVVSGECSPGRRTSDI
CCCEEECCCEEEEEEECCCEEEEEECCCEEEEEECCEEEECCCEEEEECCCCCCCCCCEE
LLLEEEM
EEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA