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The map label for this gene is cdd-2 [H]

Identifier: 116516518

GI number: 116516518

Start: 1191839

End: 1192246

Strand: Reverse

Name: cdd-2 [H]

Synonym: SPD_1164

Alternate gene names: 116516518

Gene position: 1192246-1191839 (Counterclockwise)

Preceding gene: 116515484

Following gene: 116515419

Centisome position: 58.27

GC content: 33.82

Gene sequence:

>408_bases
ATGACAGTAATTAATAAATTTGTTTTAATGGAGCAAGCAAAAAAAGTTTTAAAAAATGCTTACTGTCCGTATTCCAAATT
TCCTGTAGGTGCAGCAATTTTATTTAAAGATGGTAAAGTAATTACAGGAGCAAATATAGAAAATGTATCGTTTGGTGTAA
CTAACTGTGCAGAACGTAGTGCTATTTTTTATGGGGCTTCTCAAGGATATAGAAAAGGAGATATTCTTGCGATTGCTGTT
GCAGGTGAAACTGAAGACTACTTACCACCATGCAACATTTGTCGTCAAGTTATGGTAGAATTTTGTGAGCCTGATACCTT
AGTCTTTCTATTAAATGGTAAGGGAAACATACTTGAATTGCGATTAGAGGAATTAGTCCCATATTCGTTCTCAAGTCTAG
AAATGTAA

Upstream 100 bases:

>100_bases
TTAGAAATCGATTTGACTGTCCTGATTGATTTGTACTGTTCTTATTTCATTTTACTATAATTTAGTGTGAGTAAAATATA
ATAATAAAGGAGTTAAAACA

Downstream 100 bases:

>100_bases
TTACGTAGTATGAAATAAGGAGAAAAAAACAATGTCAGATTTGAAAAAATACGAAGGTGTCATTCCAGCCTTCTACGCAT
GTTATGATGAGCAAGGAGAA

Product: cytidine deaminase

Products: NA

Alternate protein names: CDA; Cytidine aminohydrolase [H]

Number of amino acids: Translated: 135; Mature: 134

Protein sequence:

>135_residues
MTVINKFVLMEQAKKVLKNAYCPYSKFPVGAAILFKDGKVITGANIENVSFGVTNCAERSAIFYGASQGYRKGDILAIAV
AGETEDYLPPCNICRQVMVEFCEPDTLVFLLNGKGNILELRLEELVPYSFSSLEM

Sequences:

>Translated_135_residues
MTVINKFVLMEQAKKVLKNAYCPYSKFPVGAAILFKDGKVITGANIENVSFGVTNCAERSAIFYGASQGYRKGDILAIAV
AGETEDYLPPCNICRQVMVEFCEPDTLVFLLNGKGNILELRLEELVPYSFSSLEM
>Mature_134_residues
TVINKFVLMEQAKKVLKNAYCPYSKFPVGAAILFKDGKVITGANIENVSFGVTNCAERSAIFYGASQGYRKGDILAIAVA
GETEDYLPPCNICRQVMVEFCEPDTLVFLLNGKGNILELRLEELVPYSFSSLEM

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis [H]

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI11386157, Length=124, Percent_Identity=41.1290322580645, Blast_Score=102, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17540514, Length=128, Percent_Identity=43.75, Blast_Score=105, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17551074, Length=124, Percent_Identity=45.9677419354839, Blast_Score=103, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6323274, Length=124, Percent_Identity=37.0967741935484, Blast_Score=80, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24582744, Length=140, Percent_Identity=36.4285714285714, Blast_Score=86, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24582741, Length=125, Percent_Identity=38.4, Blast_Score=78, Evalue=2e-15,
Organism=Drosophila melanogaster, GI19920920, Length=104, Percent_Identity=43.2692307692308, Blast_Score=75, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR006262
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.5 [H]

Molecular weight: Translated: 14901; Mature: 14769

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
3.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVINKFVLMEQAKKVLKNAYCPYSKFPVGAAILFKDGKVITGANIENVSFGVTNCAERS
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCEEECCCCCCEEECCCCCCCCC
AIFYGASQGYRKGDILAIAVAGETEDYLPPCNICRQVMVEFCEPDTLVFLLNGKGNILEL
EEEEECCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCEEEE
RLEELVPYSFSSLEM
EHHHHCCCCCCCCCC
>Mature Secondary Structure 
TVINKFVLMEQAKKVLKNAYCPYSKFPVGAAILFKDGKVITGANIENVSFGVTNCAERS
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCEEECCCCCCEEECCCCCCCCC
AIFYGASQGYRKGDILAIAVAGETEDYLPPCNICRQVMVEFCEPDTLVFLLNGKGNILEL
EEEEECCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCEEEE
RLEELVPYSFSSLEM
EHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]