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The map label for this gene is rpiA

Identifier: 116516446

GI number: 116516446

Start: 738108

End: 738791

Strand: Direct

Name: rpiA

Synonym: SPD_0723

Alternate gene names: 116516446

Gene position: 738108-738791 (Clockwise)

Preceding gene: 116517034

Following gene: 116516348

Centisome position: 36.07

GC content: 44.01

Gene sequence:

>684_bases
GTGGAAAATCTGAAGAAAATGGCAGGTATCAAGGCTGCTGAGTTCGTGAGCGATGGAATGGTCGTTGGACTTGGAACAGG
CTCGACTGCCTATTATTTTGTCGAAGAAATCGGTCGTCGTATCAAGGAAGAAGGATTGCAGATTACAGCTGTAACAACTT
CTAGTGTGACCACTAAACAGGCAGAAGGCCTTAATATCCCGCTCAAGTCTATTGACCAAGTAGACTTTGTCGATGTGACG
GTTGATGGCGCGGATGAAGTGGATAGTCAGTTTAATGGAATCAAAGGCGGTGGTGGTGCCCTTCTCATGGAAAAGGTGGT
CGCAACACCATCAAAAGAATACATTTGGGTGGTGGATGAAAGCAAGCTGGTCGAAAAACTAGGTGCTTTTAAATTGCCAG
TAGAAGTGGTTCAGTATGGTGCAGAGCAGGTCTTTCGTCATTTTGAACGAGCTGGCTACAAACCAAGTTTCCGTGAAAAA
GACGGCCAACGTTTTGTGACGGATATGCAGAATTTTATCATTGACCTCGCCTTGGATGTCATTGAAAATCCAATTGCTTT
TGGACAAGAATTGGACCATGTCGTTGGTGTTGTGGAGCATGGTTTATTCAACCAAATGGTGGATAAGGTAATCGTTGCTG
GACGAGATGGAGTTCAGATTTCAACTTCAAAAAAAGGAAAATAG

Upstream 100 bases:

>100_bases
TTTAAAGAAAGATTGATGAAAAATGTAGATTTGATGTTTTTACTTGAATAAAAAGCGGTTTCATAGTAAAATAAGAACTG
AGAATGATGGAGGTAAATCG

Downstream 100 bases:

>100_bases
AAGGGGGCATAAGATGTCTAAATTTAATCGTATTCATTTGGTGGTACTGGATTCTGTAGGAATCGGTGCAGCACCAGATG
CTAATAACTTTGTCAATGCA

Product: ribose-5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEEGLQITAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVT
VDGADEVDSQFNGIKGGGGALLMEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREK
DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGVQISTSKKGK

Sequences:

>Translated_227_residues
MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEEGLQITAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVT
VDGADEVDSQFNGIKGGGGALLMEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREK
DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGVQISTSKKGK
>Mature_227_residues
MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEEGLQITAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVT
VDGADEVDSQFNGIKGGGGALLMEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREK
DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGVQISTSKKGK

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family

Homologues:

Organism=Homo sapiens, GI94536842, Length=224, Percent_Identity=33.9285714285714, Blast_Score=104, Evalue=6e-23,
Organism=Escherichia coli, GI1789280, Length=219, Percent_Identity=37.4429223744292, Blast_Score=136, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI17551758, Length=237, Percent_Identity=36.7088607594937, Blast_Score=115, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6324669, Length=235, Percent_Identity=33.1914893617021, Blast_Score=96, Evalue=6e-21,
Organism=Drosophila melanogaster, GI281364072, Length=207, Percent_Identity=35.2657004830918, Blast_Score=91, Evalue=4e-19,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): RPIA_STRP2 (Q04L82)

Other databases:

- EMBL:   CP000410
- RefSeq:   YP_816216.1
- ProteinModelPortal:   Q04L82
- SMR:   Q04L82
- STRING:   Q04L82
- EnsemblBacteria:   EBSTRT00000019800
- GeneID:   4442565
- GenomeReviews:   CP000410_GR
- KEGG:   spd:SPD_0723
- eggNOG:   COG0120
- GeneTree:   EBGT00050000027278
- HOGENOM:   HBG515603
- OMA:   MVVIADA
- ProtClustDB:   PRK00702
- HAMAP:   MF_00170
- InterPro:   IPR004788
- InterPro:   IPR020672
- PANTHER:   PTHR11934
- TIGRFAMs:   TIGR00021

Pfam domain/function: PF06026 Rib_5-P_isom_A

EC number: =5.3.1.6

Molecular weight: Translated: 24793; Mature: 24793

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEEGLQITAVTTSSVTTKQ
CCCHHHHHCCHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHC
AEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALLMEKVVATPSKEYIWVVDE
CCCCCCCHHHCCCCEEEEEEECCCHHHHHHHCCCCCCCHHHHHHHHHCCCCCCEEEEECH
SKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREKDGQRFVTDMQNFIIDLALDV
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
IENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGVQISTSKKGK
HHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCC
>Mature Secondary Structure
MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEEGLQITAVTTSSVTTKQ
CCCHHHHHCCHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHC
AEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALLMEKVVATPSKEYIWVVDE
CCCCCCCHHHCCCCEEEEEEECCCHHHHHHHCCCCCCCHHHHHHHHHCCCCCCEEEEECH
SKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREKDGQRFVTDMQNFIIDLALDV
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
IENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGVQISTSKKGK
HHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA