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The map label for this gene is udk

Identifier: 116516339

GI number: 116516339

Start: 1092968

End: 1093606

Strand: Reverse

Name: udk

Synonym: SPD_1068

Alternate gene names: 116516339

Gene position: 1093606-1092968 (Counterclockwise)

Preceding gene: 116515672

Following gene: 116515460

Centisome position: 53.45

GC content: 43.97

Gene sequence:

>639_bases
ATGCAAAATAGACCAATCATTATTGGAGTGACAGGTGGTTCTGGTGGTGGTAAAACCAGTGTTTCAAGAGCCATTTTATC
GCATTTTCCTGATGAAAAGATTTCCATGATTGAGCATGATTCATACTACAAGGATCAGTCTCATTTGACCTTTGAAGAGC
GTGTCAAAACCAACTATGACCATCCTTTTGCCTTTGATACAGACTTGATGATCGAGCAGATTAAGGAATTGTTGGCAGGG
CGTCCGGTGGACATCCCGACCTACGACTATACAGAGCATACACGGAGTAGCAAGACCTATCGTCAGGAGCCTCAAGATGT
CTTTATCGTTGAGGGCATTTTGGTCTTGGAGGACAAGCGTCTGCGCGATTTGATGGATATCAAGATTTTTGTGGATACGG
ATGACGATGTGCGTATTATTCGTCGTATCAAGCGTGATATGGAGGAGCGTGGCCGTAGCCTTGATAGCGTTATTAACCAG
TACTTAGGTGTGGTCAAACCAATGTACCACCAGTTTATCGAGTCAACTAAGCGTTATGCTGATATCGTCATTCCTGAAGG
GGTTAGCAATACCGTGGCTATCGACCTGTTGACGACCAAGATTGCAAAGATTTTGGAAGAAGCTCGAAACAGCAAATAA

Upstream 100 bases:

>100_bases
GAACATCAGAGGGAAGACTCTGGTGTTTTTTGCTGATGAGACTATAAATTTTGTAAAAAATGTGATAGAATAGACGACGG
ATAAAATAACGGAGGATAGC

Downstream 100 bases:

>100_bases
TCACATGTGGAGGCCTTGCCTCCTTTTTCTATTTTTCCCTCATAATGGTACATAAATGGAGATTTTTAGGCATATTTTTG
GTATAATAATACCCATGAAA

Product: uridine kinase

Products: NA

Alternate protein names: Cytidine monophosphokinase; Uridine monophosphokinase

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYKDQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAG
RPVDIPTYDYTEHTRSSKTYRQEPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK

Sequences:

>Translated_212_residues
MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYKDQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAG
RPVDIPTYDYTEHTRSSKTYRQEPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK
>Mature_212_residues
MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYKDQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAG
RPVDIPTYDYTEHTRSSKTYRQEPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK

Specific function: Pyrimidine salvage pathway. [C]

COG id: COG0572

COG function: function code F; Uridine kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uridine kinase family

Homologues:

Organism=Homo sapiens, GI301129207, Length=202, Percent_Identity=44.5544554455446, Blast_Score=178, Evalue=3e-45,
Organism=Homo sapiens, GI57863312, Length=202, Percent_Identity=44.5544554455446, Blast_Score=178, Evalue=4e-45,
Organism=Homo sapiens, GI18699734, Length=213, Percent_Identity=40.3755868544601, Blast_Score=176, Evalue=2e-44,
Organism=Homo sapiens, GI13899253, Length=216, Percent_Identity=40.7407407407407, Blast_Score=170, Evalue=1e-42,
Organism=Homo sapiens, GI209863022, Length=155, Percent_Identity=38.7096774193548, Blast_Score=113, Evalue=1e-25,
Organism=Escherichia coli, GI87082034, Length=208, Percent_Identity=50.4807692307692, Blast_Score=219, Evalue=8e-59,
Organism=Caenorhabditis elegans, GI17539894, Length=208, Percent_Identity=40.8653846153846, Blast_Score=168, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI17539892, Length=208, Percent_Identity=40.8653846153846, Blast_Score=167, Evalue=3e-42,
Organism=Caenorhabditis elegans, GI71981181, Length=213, Percent_Identity=36.150234741784, Blast_Score=128, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6324339, Length=199, Percent_Identity=36.1809045226131, Blast_Score=115, Evalue=4e-27,
Organism=Saccharomyces cerevisiae, GI6320223, Length=213, Percent_Identity=24.8826291079812, Blast_Score=69, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24649624, Length=221, Percent_Identity=39.3665158371041, Blast_Score=169, Evalue=1e-42,
Organism=Drosophila melanogaster, GI221458995, Length=216, Percent_Identity=39.8148148148148, Blast_Score=166, Evalue=1e-41,
Organism=Drosophila melanogaster, GI28573516, Length=207, Percent_Identity=38.6473429951691, Blast_Score=165, Evalue=2e-41,
Organism=Drosophila melanogaster, GI28573514, Length=207, Percent_Identity=38.6473429951691, Blast_Score=165, Evalue=2e-41,
Organism=Drosophila melanogaster, GI28573512, Length=207, Percent_Identity=38.6473429951691, Blast_Score=165, Evalue=2e-41,
Organism=Drosophila melanogaster, GI45550449, Length=207, Percent_Identity=38.6473429951691, Blast_Score=165, Evalue=2e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): URK_STRP2 (Q04KA9)

Other databases:

- EMBL:   CP000410
- RefSeq:   YP_816539.1
- ProteinModelPortal:   Q04KA9
- SMR:   Q04KA9
- STRING:   Q04KA9
- EnsemblBacteria:   EBSTRT00000019223
- GeneID:   4442822
- GenomeReviews:   CP000410_GR
- KEGG:   spd:SPD_1068
- eggNOG:   COG0572
- GeneTree:   EBGT00050000027703
- HOGENOM:   HBG527126
- OMA:   NQFVEPT
- ProtClustDB:   PRK05480
- GO:   GO:0005737
- HAMAP:   MF_00551
- InterPro:   IPR006083
- InterPro:   IPR000764
- PANTHER:   PTHR10285:SF6
- PRINTS:   PR00988
- TIGRFAMs:   TIGR00235

Pfam domain/function: PF00485 PRK

EC number: =2.7.1.48

Molecular weight: Translated: 24466; Mature: 24466

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYKDQSHLTFEERVKTNYD
CCCCCEEEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCHHHHHHCCCC
HPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQEPQDVFIVEGILVLEDKR
CCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCHHHHCCCCCEEEECCEEEECCHH
LRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQYLGVVKPMYHQFIESTKRYA
HHHHHEEEEEEECCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DIVIPEGVSNTVAIDLLTTKIAKILEEARNSK
EEECCCCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYKDQSHLTFEERVKTNYD
CCCCCEEEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCHHHHHHCCCC
HPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQEPQDVFIVEGILVLEDKR
CCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCHHHHCCCCCEEEECCEEEECCHH
LRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQYLGVVKPMYHQFIESTKRYA
HHHHHEEEEEEECCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DIVIPEGVSNTVAIDLLTTKIAKILEEARNSK
EEECCCCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA