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The map label for this gene is engD [H]

Identifier: 116516338

GI number: 116516338

Start: 3000

End: 4115

Strand: Direct

Name: engD [H]

Synonym: SPD_0004

Alternate gene names: 116516338

Gene position: 3000-4115 (Clockwise)

Preceding gene: 116515850

Following gene: 116515731

Centisome position: 0.15

GC content: 39.96

Gene sequence:

>1116_bases
ATGGCTTTGACAGCAGGTATCGTTGGTTTGCCAAACGTTGGTAAATCAACACTATTTAATGCAATTACAAAAGCAGGAGC
AGAGGCAGCAAACTACCCATTTGCGACTATTGATCCAAATGTTGGAATGGTGGAAGTTCCAGATGAACGCCTACAAAAAC
TAACTGAAATGATAACTCCTAAAAAGACAGTTCCCACAACATTTGAATTTACAGATATTGCAGGGATTGTAAAAGGAGCT
TCAAAAGGAGAAGGGCTAGGGAATAAATTCTTGGCCAATATTCGTGAAGTAGATGCGATTGTTCACGTAGTTCGTGCTTT
TGATGATGAAAATGTAATGCGCGAGCAAGGACGTGAAGACGCCTTTGTAGATCCACTTGCAGATATTGATACAATTAATC
TGGAATTAATTCTTGCTGACTTAGAATCAGTGAACAAACGATATGCGCGTGTAGAAAAGATGGCACGTACGCAAAAAGAT
AAAGAATCAGTAGCAGAATTCAATGTTCTTCAAAAGATTAAACCAGTCCTAGAAGACGGGAAATCAGCTCGTACCATTGA
ATTTACAGATGAGGAACAAAAGGTTGTCAAAGGTCTTTTCCTTTTGACGACTAAACCAGTTCTTTATGTAGCTAATGTGG
ACGAGGATGTGGTTTCAGAACCTGACTCTATCGACTATGTCAAACAAATTCGTGAATTTGCAGCGACAGAAAATGCTGAA
GTAGTCGTTATTTCTGCGCGTGCTGAGGAAGAAATTTCTGAATTGGATGATGAAGATAAAAAAGAGTTTCTTGAAGCCAT
TGGTTTGACAGAATCAGGTGTAGATAAGTTGACGCGTGCAGCTTACCACTTGCTTGGATTGGGAACTTACTTCACAGCTG
GTGAAAAAGAAGTTCGCGCTTGGACTTTCAAACGTGGTATGAAGGCTCCTCAAGCAGCTGGTATTATCCACTCAGACTTT
GAAAAAGGCTTTATTCGTGCAGTAACCATGTCATATGAAGATCTAGTGAAATACGGATCTGAAAAGGCCGTAAAAGAAGC
TGGACGCTTGCGTGAAGAAGGAAAAGAATATATCGTTCAAGATGGCGATATCATGGAATTCCGCTTTAATGTCTAA

Upstream 100 bases:

>100_bases
ATAAAATTATTGACTGAGAACCCTTAGTTAGAGGGTTAGCACTTTATCCCTTTTTGTGTTATAATATTAGGGATTGAAAT
GAAAACGGAGAATGAGAAAT

Downstream 100 bases:

>100_bases
AAATTAATAAATGGTGTCAATTAGGTTGGAAAAAAATTCCAACCCTTTTGGCTTTTGAAAGGAAAAATAAATGACCAAAT
TACTTGTAGGTTTGGGAAAT

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 371; Mature: 370

Protein sequence:

>371_residues
MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMVEVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGA
SKGEGLGNKFLANIREVDAIVHVVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVVSEPDSIDYVKQIREFAATENAE
VVVISARAEEEISELDDEDKKEFLEAIGLTESGVDKLTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDF
EKGFIRAVTMSYEDLVKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV

Sequences:

>Translated_371_residues
MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMVEVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGA
SKGEGLGNKFLANIREVDAIVHVVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVVSEPDSIDYVKQIREFAATENAE
VVVISARAEEEISELDDEDKKEFLEAIGLTESGVDKLTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDF
EKGFIRAVTMSYEDLVKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV
>Mature_370_residues
ALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMVEVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGAS
KGEGLGNKFLANIREVDAIVHVVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKDK
ESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVVSEPDSIDYVKQIREFAATENAEV
VVISARAEEEISELDDEDKKEFLEAIGLTESGVDKLTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFE
KGFIRAVTMSYEDLVKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=374, Percent_Identity=43.3155080213904, Blast_Score=298, Evalue=5e-81,
Organism=Homo sapiens, GI58761502, Length=226, Percent_Identity=40.7079646017699, Blast_Score=162, Evalue=6e-40,
Organism=Escherichia coli, GI1787454, Length=371, Percent_Identity=54.4474393530997, Blast_Score=411, Evalue=1e-116,
Organism=Escherichia coli, GI1789574, Length=145, Percent_Identity=27.5862068965517, Blast_Score=73, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17509631, Length=371, Percent_Identity=41.2398921832884, Blast_Score=291, Evalue=4e-79,
Organism=Saccharomyces cerevisiae, GI6319499, Length=377, Percent_Identity=42.1750663129974, Blast_Score=268, Evalue=1e-72,
Organism=Saccharomyces cerevisiae, GI6321773, Length=386, Percent_Identity=35.7512953367876, Blast_Score=207, Evalue=2e-54,
Organism=Saccharomyces cerevisiae, GI6321649, Length=248, Percent_Identity=31.0483870967742, Blast_Score=95, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24640873, Length=374, Percent_Identity=41.9786096256684, Blast_Score=279, Evalue=3e-75,
Organism=Drosophila melanogaster, GI24640877, Length=374, Percent_Identity=41.9786096256684, Blast_Score=279, Evalue=3e-75,
Organism=Drosophila melanogaster, GI24640875, Length=374, Percent_Identity=41.9786096256684, Blast_Score=279, Evalue=3e-75,
Organism=Drosophila melanogaster, GI24640879, Length=333, Percent_Identity=39.9399399399399, Blast_Score=227, Evalue=1e-59,
Organism=Drosophila melanogaster, GI24585318, Length=174, Percent_Identity=31.0344827586207, Blast_Score=79, Evalue=4e-15,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 41172; Mature: 41041

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMVEVPDERLQKLTEMITP
CCCCCCCCCCCCCCHHHHHHHHHHHCCHHCCCCCEEECCCCCEEECCHHHHHHHHHHHCC
KKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVHVVRAFDDENVMREQGRED
CCCCCCEEEHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCC
AFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKDKESVAEFNVLQKIKPVLEDG
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVVSEPDSIDYVKQIREFAATENAE
CCCEEEEECCHHHHHHHHHHHEECCCEEEEECCCHHHHCCCCCHHHHHHHHHHHCCCCCC
VVVISARAEEEISELDDEDKKEFLEAIGLTESGVDKLTRAAYHLLGLGTYFTAGEKEVRA
EEEEECCCHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
WTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYEDLVKYGSEKAVKEAGRLREEGKEYIVQ
HHHHHCCCCCHHCCCHHHHHHHHHHHHHHHCHHHHHHHCCHHHHHHHHHHHHHCHHHEEC
DGDIMEFRFNV
CCCEEEEEECC
>Mature Secondary Structure 
ALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMVEVPDERLQKLTEMITP
CCCCCCCCCCCCCHHHHHHHHHHHCCHHCCCCCEEECCCCCEEECCHHHHHHHHHHHCC
KKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVHVVRAFDDENVMREQGRED
CCCCCCEEEHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCC
AFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKDKESVAEFNVLQKIKPVLEDG
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVVSEPDSIDYVKQIREFAATENAE
CCCEEEEECCHHHHHHHHHHHEECCCEEEEECCCHHHHCCCCCHHHHHHHHHHHCCCCCC
VVVISARAEEEISELDDEDKKEFLEAIGLTESGVDKLTRAAYHLLGLGTYFTAGEKEVRA
EEEEECCCHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
WTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYEDLVKYGSEKAVKEAGRLREEGKEYIVQ
HHHHHCCCCCHHCCCHHHHHHHHHHHHHHHCHHHHHHHCCHHHHHHHHHHHHHCHHHEEC
DGDIMEFRFNV
CCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]