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The map label for this gene is trpD

Identifier: 116516280

GI number: 116516280

Start: 1615393

End: 1616397

Strand: Reverse

Name: trpD

Synonym: SPD_1600

Alternate gene names: 116516280

Gene position: 1616397-1615393 (Counterclockwise)

Preceding gene: 116516075

Following gene: 116516838

Centisome position: 79.0

GC content: 43.98

Gene sequence:

>1005_bases
ATGAAAGAGATTATTGAAAAACTAGCAAAATTTGAAAATTTATCAGGTGTGGAAATGACGGATGTCATTGAGCGTATCGT
AACTGGGCGTGTAACTGAAGCGCAGATTGCTTCTCTCCTCTTAGCTCTTAAGATGAAGGGGGAAACACCTGAAGAACGCA
CAGCCATTGCCCAAGTCATGAGAGGACATGCCCAGCATATTCCAACTGAGATTCATGATGCCATGGACAACTGTGGTACA
GGTGGGGACAAGTCTTTCAGTTTTAATATTTCCACAACTGCAGCCTTTGTCTTGGCTGGTGGCGGTATTCACATGGCCAA
GCATGGTAACCGCTCGATTTCTTCTAAATCTGGTTCCGCAGATGTCCTCGAAGCCTTGGGAATCAATCTTGACCTCAAAC
CAGCTGAACTAGGTAAGGTCTTTGATAAAACTGGAATCGTCTTTCTCTTCGCTAAAAATATGCACCCAGCTATGAAATAC
ATCATGCCAGCTCGTTTGGAATTGGGAATTCCAACGATTATGAACTTGACTGGTCCACTGATTCATCCAATGGCTTTAGA
AACACAGCTTCTTGGAATTAGTCGTCCAGAACTCCTAGAAAGTACAGCTCAGGTTTTGAAAAATATGGGTCGCAAACGTG
CCATCGTGGTTGCTGGACCAGAAGGGTTGGATGAAGCTGGCTTGAACGGAACAACCAAGATTGCACTTCTTGAAAATGGC
GAAATCAGCTTGTCAAGCTTTACTCCAGAGGATTTGGGAATGGAAGGCTATGCTATGGAAGATATTCGTGGTGGGAATGC
TCAGGAAAATGCAGAAATTTTGCTTAGCGTTCTGAAAAACGAAGCAAGTCCATTCTTGGAAACGACAGTCTTGAATGCTG
GTCTTGGTTTCTATGCTAATGGTAAGATTGATAGCATCAAGGAAGGAGTTGCCTTGGCCCGTCAAGTGATTGCTAGAGGC
AAGGCCCTTGAAAAACTCAGACTGTTACAGGAGTACCAAAAATGA

Upstream 100 bases:

>100_bases
ATTTATGGCTTCCAGTACCATCCAGAGAGCATTGGAACGCCAGACGGCTTGTCTTCTATTCGGAATTTTATCGAGGAGGT
TGTAAAGTGAGGAAACTAGG

Downstream 100 bases:

>100_bases
GTCAGGAATTTTTAGCACGAATCTTAGAGCAGAAGGCGCGTGAGGTGGAGCAGATGAAGCTGGAGCAAATCCAGCCTCTG
CGCCAGACCTATCGCTTGGC

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALKMKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGT
GGDKSFSFNISTTAAFVLAGGGIHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVAGPEGLDEAGLNGTTKIALLENG
EISLSSFTPEDLGMEGYAMEDIRGGNAQENAEILLSVLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARG
KALEKLRLLQEYQK

Sequences:

>Translated_334_residues
MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALKMKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGT
GGDKSFSFNISTTAAFVLAGGGIHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVAGPEGLDEAGLNGTTKIALLENG
EISLSSFTPEDLGMEGYAMEDIRGGNAQENAEILLSVLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARG
KALEKLRLLQEYQK
>Mature_334_residues
MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALKMKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGT
GGDKSFSFNISTTAAFVLAGGGIHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVAGPEGLDEAGLNGTTKIALLENG
EISLSSFTPEDLGMEGYAMEDIRGGNAQENAEILLSVLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARG
KALEKLRLLQEYQK

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=279, Percent_Identity=39.7849462365591, Blast_Score=185, Evalue=3e-48,
Organism=Saccharomyces cerevisiae, GI6320561, Length=270, Percent_Identity=29.6296296296296, Blast_Score=109, Evalue=5e-25,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_STRP2 (Q04IY6)

Other databases:

- EMBL:   CP000410
- RefSeq:   YP_817052.1
- ProteinModelPortal:   Q04IY6
- SMR:   Q04IY6
- STRING:   Q04IY6
- EnsemblBacteria:   EBSTRT00000020617
- GeneID:   4442608
- GenomeReviews:   CP000410_GR
- KEGG:   spd:SPD_1600
- eggNOG:   COG0547
- GeneTree:   EBGT00050000029260
- HOGENOM:   HBG559996
- OMA:   LGVYSPE
- ProtClustDB:   PRK00188
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 35905; Mature: 35905

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALKMKGETPEERTAIAQVM
CHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHH
RGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGGIHMAKHGNRSISSKSGSA
HHHHHHCCHHHHHHHHHCCCCCCCEEEEEEHHHEEEEEECCCEEEECCCCCCCCCCCCCH
DVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKYIMPARLELGIPTIMNLTGPL
HHHHHHCCCCCCCHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHCCCCHHHHCCCCH
IHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVAGPEGLDEAGLNGTTKIALLENG
HCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCEEEEEEECC
EISLSSFTPEDLGMEGYAMEDIRGGNAQENAEILLSVLKNEASPFLETTVLNAGLGFYAN
CEEECCCCHHHCCCCCCCHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEC
GKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALKMKGETPEERTAIAQVM
CHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHH
RGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGGIHMAKHGNRSISSKSGSA
HHHHHHCCHHHHHHHHHCCCCCCCEEEEEEHHHEEEEEECCCEEEECCCCCCCCCCCCCH
DVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKYIMPARLELGIPTIMNLTGPL
HHHHHHCCCCCCCHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHCCCCHHHHCCCCH
IHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVAGPEGLDEAGLNGTTKIALLENG
HCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCEEEEEEECC
EISLSSFTPEDLGMEGYAMEDIRGGNAQENAEILLSVLKNEASPFLETTVLNAGLGFYAN
CEEECCCCHHHCCCCCCCHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEC
GKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA