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The map label for this gene is pyrK [H]

Identifier: 116515976

GI number: 116515976

Start: 864710

End: 865510

Strand: Direct

Name: pyrK [H]

Synonym: SPD_0851

Alternate gene names: 116515976

Gene position: 864710-865510 (Clockwise)

Preceding gene: 116515712

Following gene: 116517057

Centisome position: 42.26

GC content: 44.94

Gene sequence:

>801_bases
ATGAATCTCACATGTAAGAAGCGTTTGGGTGTCATTCGGTTGGAAACCATGAAGGTGGTTGCACAAGAGGAAATCGCGCC
AGCAATCTTTGAATTAGTCCTAGAAGGAGAAATGGTTGAAGCCATGCGAGCAGGCCAATTTCTTCATCTGCGTGTACCAG
ACGATGCCCATCTCTTACGTCGTCCTATTTCAATTTCGTCTATTGACAAGGCAAACAAGCAGTGTCACCTCATTTATCGG
ATTGAGGGAGCTGGGACTGCAATTTTTTCAACCTTAAGTCAGGGAGACACTCTTGATGTGATGGGGCCTCAGGGAAATGG
TTTTGACTTGTCTGACCTTGATGAGCAGAATCAGGTTCTCCTTGTTGGTGGTGGGATTGGTGTTCCACCCTTGCTTGAGG
TGGCCAAGGAATTGCATGAACGTGGAGTGAAAGTAGTGACAGTCCTCGGTTTTGCTAATAAGGATGCTGTTATTTTGAAA
ACGGAATTGGCTCAGTATGGTCAGGTCTTTGTAACGACAGATGATGGTTCTTATGGCATCAAGGGAAATGTTTCCGTTGT
TATCAATGATTTAGATAGTCAGTTTGATGCTGTTTACTCGTGTGGGGCTCCAGGAATGATGAAGTATATCAATCAAACCT
TTGATGATCACCCAAGAGCCTATTTATCTCTGGAATCTCGTATGGCTTGTGGGATGGGAGCTTGCTATGCCTGTGTTCTA
AAAGTACCAGAAAGCGAGACGGTCAGCCAACGCGTCTGTGAAGATGGTCCTGTTTTCCGCACAGGAACAGTTGTATTATA
A

Upstream 100 bases:

>100_bases
TTTGAGTGTGCTCTCTTGTGTTGTACGATTTTAACTGAGGCCTTGCACTAGCAAGGTCTTTTCTTTATCTGGTCCCCTTA
AAATTTAAGGAGGAAAAGTT

Downstream 100 bases:

>100_bases
GGAGAAAATTATGACTACAAATCGATTACAAGTGTCTCTACCTGGTTTGGATTTGAAAAATCCGATTATTCCAGCATCAG
GCTGTTTTGGCTTTGGACAA

Product: dihydroorotate dehydrogenase electron transfer subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MNLTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRAGQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYR
IEGAGTAIFSTLSQGDTLDVMGPQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHPRAYLSLESRMACGMGACYACVL
KVPESETVSQRVCEDGPVFRTGTVVL

Sequences:

>Translated_266_residues
MNLTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRAGQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYR
IEGAGTAIFSTLSQGDTLDVMGPQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHPRAYLSLESRMACGMGACYACVL
KVPESETVSQRVCEDGPVFRTGTVVL
>Mature_266_residues
MNLTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRAGQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYR
IEGAGTAIFSTLSQGDTLDVMGPQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHPRAYLSLESRMACGMGACYACVL
KVPESETVSQRVCEDGPVFRTGTVVL

Specific function: Is responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the pyrD subunit to the ultimate electron acceptor NAD(+) [H]

COG id: COG0543

COG function: function code HC; 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012165
- InterPro:   IPR019480
- InterPro:   IPR017927
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR000951
- InterPro:   IPR017938 [H]

Pfam domain/function: PF10418 DHODB_Fe-S_bind; PF00970 FAD_binding_6; PF00175 NAD_binding_1 [H]

EC number: NA

Molecular weight: Translated: 28884; Mature: 28884

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRAGQFLHLRVPDDAHLLR
CCCCHHHHCCEEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCEEEEECCCCHHHHH
RPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMGPQGNGFDLSDLDEQNQVL
CCCCCHHHHCCCCEEEEEEEECCCCHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCEE
LVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILKTELAQYGQVFVTTDDGSYGI
EEECCCCCCHHHHHHHHHHHCCCEEEEEEEECCCCEEEEEECHHHCCEEEEEECCCCCCC
KGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHPRAYLSLESRMACGMGACYACVL
CCCEEEEEECCCHHHHHHHCCCCCHHHHHHHHCCCCCCCEEEEEHHHHHCCCHHHEEEEE
KVPESETVSQRVCEDGPVFRTGTVVL
ECCCCHHHHHHHCCCCCEEECCCEEC
>Mature Secondary Structure
MNLTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRAGQFLHLRVPDDAHLLR
CCCCHHHHCCEEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCEEEEECCCCHHHHH
RPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMGPQGNGFDLSDLDEQNQVL
CCCCCHHHHCCCCEEEEEEEECCCCHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCEE
LVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILKTELAQYGQVFVTTDDGSYGI
EEECCCCCCHHHHHHHHHHHCCCEEEEEEEECCCCEEEEEECHHHCCEEEEEECCCCCCC
KGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHPRAYLSLESRMACGMGACYACVL
CCCEEEEEECCCHHHHHHHCCCCCHHHHHHHHCCCCCCCEEEEEHHHHHCCCHHHEEEEE
KVPESETVSQRVCEDGPVFRTGTVVL
ECCCCHHHHHHHCCCCCEEECCCEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11544234 [H]