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The map label for this gene is comEB [H]

Identifier: 116515918

GI number: 116515918

Start: 667608

End: 668075

Strand: Direct

Name: comEB [H]

Synonym: SPD_0648

Alternate gene names: 116515918

Gene position: 667608-668075 (Clockwise)

Preceding gene: 116517044

Following gene: 116515358

Centisome position: 32.63

GC content: 44.87

Gene sequence:

>468_bases
ATGACTGAAAAAAGACTGGCCTGGGATGAGTATTTTGCAGCCCAAGCTCTACTAATTGCGAATCGTTCCACTTGTAAACG
TGCTAAAGTGGGCGCGATTCTGGTAAAAGATAATAAGGTTATTTCCACTGGTTACAATGGTTCGGTGTCAGGGACTGAGC
ATTGTATTGATCACGAATGTTTGGTCATTGAAGGCCACTGCGTTCGCACCCTTCACGCTGAGGTCAATGCTATCCTTCAA
GGTGCTGAGCGTGGTGTTCCCAAAGGCTTTACAGCCTATGTAACCCATTTTCCTTGTCTCAACTGTACAAAACAATTGCT
TCAGGTCGGCTGCAAGCGCGTGGTTTATATCAACCAGTACCGAATGGACGACTACGCCCAATACCTTTATCAAGAAAAAG
GGACAGAATTGACCCATTTACCACTTGAGACAGTACAGACAGCTCTTAAAGAGGCTGATCTAATGTAA

Upstream 100 bases:

>100_bases
CCTTCTAAAATGGATCAAGGATGGCATGAAGGTACCAGCTGAAAAGATTGCAGATTTAGGTTTACCATTTTTTAAAAAAT
AGAGAAAAAGGAGAAAAGAG

Downstream 100 bases:

>100_bases
AAATTATCAAAAATAAATGGTTTAGAAAGATTTTTAAACCGTTTTTTGGTATAATAAGAAGAATAAATTGAAAGAAGGAA
TTCCAAAAATGGGAAAAATT

Product: cytidine and deoxycytidylate deaminase family protein

Products: dUMP; NH3

Alternate protein names: NA

Number of amino acids: Translated: 155; Mature: 154

Protein sequence:

>155_residues
MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTGYNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQ
GAERGVPKGFTAYVTHFPCLNCTKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM

Sequences:

>Translated_155_residues
MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTGYNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQ
GAERGVPKGFTAYVTHFPCLNCTKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM
>Mature_154_residues
TEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTGYNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQG
AERGVPKGFTAYVTHFPCLNCTKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM

Specific function: Dispensable for transformability [H]

COG id: COG2131

COG function: function code F; Deoxycytidylate deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI61742819, Length=131, Percent_Identity=37.4045801526718, Blast_Score=69, Evalue=1e-12,
Organism=Homo sapiens, GI61742821, Length=127, Percent_Identity=36.2204724409449, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6321938, Length=136, Percent_Identity=35.2941176470588, Blast_Score=91, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24667298, Length=131, Percent_Identity=34.3511450381679, Blast_Score=70, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24667302, Length=131, Percent_Identity=34.3511450381679, Blast_Score=70, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR013404
- InterPro:   IPR015517
- InterPro:   IPR016193
- InterPro:   IPR016473 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: 3.5.4.12

Molecular weight: Translated: 17395; Mature: 17264

Theoretical pI: Translated: 7.43; Mature: 7.43

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
4.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTGYNGSVSGTEHCIDHEC
CCCCCCHHHHHHHHHHHEEECCCHHHHHHCCEEEEECCEEEECCCCCCCCCCHHHCCCCE
LVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNCTKQLLQVGCKRVVYINQY
EEEECCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHCCCEEEEEEEE
RMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM
CHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHCCC
>Mature Secondary Structure 
TEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTGYNGSVSGTEHCIDHEC
CCCCCHHHHHHHHHHHEEECCCHHHHHHCCEEEEECCEEEECCCCCCCCCCHHHCCCCE
LVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNCTKQLLQVGCKRVVYINQY
EEEECCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHCCCEEEEEEEE
RMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM
CHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: dCMP; H2O

Specific reaction: dCMP + H2O = dUMP + NH3

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7968523; 8969508; 9384377 [H]