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The map label for this gene is coaD

Identifier: 116515643

GI number: 116515643

Start: 1765068

End: 1765556

Strand: Reverse

Name: coaD

Synonym: SPD_1766

Alternate gene names: 116515643

Gene position: 1765556-1765068 (Counterclockwise)

Preceding gene: 116516705

Following gene: 116516010

Centisome position: 86.29

GC content: 39.47

Gene sequence:

>489_bases
ATGTCAGATAAGATTGGCTTATTCACAGGCTCATTTGATCCGATGACAAATGGGCATCTGGATATCATTGAACGGGCGAG
CAGACTTTTTGATAAGCTTTATGTGGGTATTTTTTTTAATCCCCACAAACAAGGATTTCTTCCTATCGAAAATCGTAAAC
GGGGGCTAGAAAAGGCTTTGGGACATCTGGAAAATGTTGAAGTCGTGGCTTCTCATGATGAATTGGTGGTCGATGTTGCA
AAAAGATTGGGTGCTACTTGTCTAGTGCGTGGTTTGAGGAATGCGTCGGATTTGCAATATGAAGCCAGTTTTGATTACTA
CAATCATCAGCTGTCTTCTGATATAGAGACTATTTATTTACATAGTCGACCTGAACATCTCTATATCAGTTCATCAGGCG
TTAGAGAGCTTTTGAAGTTTGGTCAGGATATTGCCTGCTATGTTCCCGAGAGTATTTTGGAGGAAATAAGAAATGAAAAA
AAAGATTAG

Upstream 100 bases:

>100_bases
GTTGTGTGCGAGACGGATAAGGCCGTTGAACTTCCAGAAGAGATTGCCTGTCTGGGTATCTGGAAGGAAAAGATTTATGG
AATTAGTAAGGTGACAGTCT

Downstream 100 bases:

>100_bases
ATGGCCCTTATACGTCATTGCGGCCTTGATTGTGACTTTCTTGGCATTTGTAGTGCCCTTGCCTTATTATATAGAGGTTC
CAGGTGGTTCGGAAGATATT

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 162; Mature: 161

Protein sequence:

>162_residues
MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLYVGIFFNPHKQGFLPIENRKRGLEKALGHLENVEVVASHDELVVDVA
KRLGATCLVRGLRNASDLQYEASFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACYVPESILEEIRNEK
KD

Sequences:

>Translated_162_residues
MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLYVGIFFNPHKQGFLPIENRKRGLEKALGHLENVEVVASHDELVVDVA
KRLGATCLVRGLRNASDLQYEASFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACYVPESILEEIRNEK
KD
>Mature_161_residues
SDKIGLFTGSFDPMTNGHLDIIERASRLFDKLYVGIFFNPHKQGFLPIENRKRGLEKALGHLENVEVVASHDELVVDVAK
RLGATCLVRGLRNASDLQYEASFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACYVPESILEEIRNEKK
D

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=150, Percent_Identity=36.6666666666667, Blast_Score=115, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_STRP2 (Q04IK0)

Other databases:

- EMBL:   CP000410
- RefSeq:   YP_817188.1
- ProteinModelPortal:   Q04IK0
- SMR:   Q04IK0
- STRING:   Q04IK0
- EnsemblBacteria:   EBSTRT00000020380
- GeneID:   4441323
- GenomeReviews:   CP000410_GR
- KEGG:   spd:SPD_1766
- eggNOG:   COG0669
- GeneTree:   EBGT00050000028176
- HOGENOM:   HBG288308
- OMA:   VRQIAAM
- ProtClustDB:   PRK00168
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 18471; Mature: 18340

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLYVGIFFNPHKQGFLPIENRKRGLEKAL
CCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHH
GHLENVEVVASHDELVVDVAKRLGATCLVRGLRNASDLQYEASFDYYNHQLSSDIETIYL
HHHCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHCCCEEEEE
HSRPEHLYISSSGVRELLKFGQDIACYVPESILEEIRNEKKD
ECCCCEEEEECHHHHHHHHCCCCEEEECCHHHHHHHHHCCCC
>Mature Secondary Structure 
SDKIGLFTGSFDPMTNGHLDIIERASRLFDKLYVGIFFNPHKQGFLPIENRKRGLEKAL
CCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHH
GHLENVEVVASHDELVVDVAKRLGATCLVRGLRNASDLQYEASFDYYNHQLSSDIETIYL
HHHCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHCCCEEEEE
HSRPEHLYISSSGVRELLKFGQDIACYVPESILEEIRNEKKD
ECCCCEEEEECHHHHHHHHCCCCEEEECCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA