BacMap

Definition	Streptococcus pneumoniae D39, complete genome.
Accession	NC_008533
Length	2,046,115

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The map label for this gene is ftsH [H]

Identifier: 116515587

GI number: 116515587

Start: 12174

End: 14132

Strand: Direct

Name: ftsH [H]

Synonym: SPD_0013

Alternate gene names: 116515587

Gene position: 12174-14132 (Clockwise)

Preceding gene: 116516681

Following gene: 116515336

Centisome position: 0.59

GC content: 39.2

Gene sequence:

>1959_bases
ATGAAAAAACAAAATAATGGTTTAATTAAAAATCCTTTTCTATGGTTATTATTTATCTTTTTCCTTGTGACAGGATTCCA
GTATTTCTATTCTGGGAATAACTCAGGAGGAAGTCAGCAAATCAACTATACTGAGTTGGTACAAGAAATTACCGATGGTA
ATGTAAAAGAATTAACTTACCAACCAAATGGTAGTGTTATCGAAGTTTCTGGTGTCTATAAAAATCCTAAAACAAGTAAA
GAAGGAACAGGTATTCAGTTTTTCACGCCATCTGTTACTAAGGTAGAGAAATTTACCAGCACTATTCTTCCTGCAGATAC
TACCGTATCAGAATTGCAAAAACTTGCTACTGACCATAAAGCAGAAGTAACTGTTAAGCATGAAAGTTCAAGTGGTATAT
GGATTAATCTACTCGTATCCATTGTGCCATTTGGAATTCTATTCTTCTTCCTATTCTCTATGATGGGAAATATGGGAGGA
GGCAATGGCCGTAATCCAATGAGTTTTGGACGTAGTAAGGCTAAAGCAGCAAATAAAGAAGATATTAAAGTAAGATTTTC
AGATGTTGCTGGAGCTGAGGAAGAAAAACAAGAACTAGTTGAAGTTGTTGAGTTCTTAAAAGATCCAAAACGATTCACAA
AACTTGGAGCCCGTATTCCAGCAGGTGTTCTTTTGGAGGGACCTCCGGGGACAGGTAAGACTTTGCTTGCTAAGGCAGTC
GCTGGAGAAGCAGGTGTTCCATTCTTTAGTATCTCAGGTTCTGACTTTGTAGAAATGTTTGTCGGAGTTGGAGCTAGTCG
TGTTCGCTCTCTTTTTGAGGATGCCAAAAAAGCAGCACCAGCTATCATCTTTATCGATGAAATTGATGCTGTTGGACGTC
AACGTGGAGTCGGTCTCGGCGGAGGTAATGACGAACGTGAACAAACCTTGAACCAACTTTTGATTGAGATGGATGGTTTT
GAGGGAAATGAAGGGATTATCGTCATCGCTGCGACAAACCGTTCAGATGTACTTGATCCTGCCCTTTTGCGTCCAGGACG
TTTTGATAGAAAAGTATTGGTTGGCCGTCCTGATGTTAAAGGTCGTGAAGCAATCTTGAAAGTTCACGCTAAGAACAAGC
CTTTAGCAGAAGATGTTGATTTGAAATTAGTGGCTCAACAAACTCCAGGCTTTGTTGGTGCTGATTTAGAGAATGTCTTG
AATGAAGCAGCTTTAGTTGCTGCTCGTCGCAATAAATCGATAATTGATGCTTCAGATATTGATGAAGCAGAAGATAGAGT
TATTGCTGGACCTTCTAAGAAAGATAAGACAGTTTCACAAAAAGAACGAGAATTGGTTGCTTACCATGAGGCAGGACATA
CCATTGTTGGTCTAGTCTTGTCGAATGCTCGCGTTGTCCATAAGGTTACAATTGTACCACGCGGCCGTGCAGGCGGATAC
ATGATTGCACTTCCTAAAGAGGATCAAATGCTTCTATCTAAAGAAGATATGAAAGAGCAATTGGCTGGCTTAATGGGTGG
ACGTGTAGCTGAAGAAATTATCTTTAATGTCCAAACTACAGGAGCTTCAAACGACTTTGAACAAGCGACACAAATGGCAC
GTGCAATGGTTACAGAGTACGGTATGAGTGAAAAACTTGGCCCAGTACAATATGAAGGAAACCATGCTATGCTTGGTGCA
CAGAGTCCTCAAAAATCAATTTCAGAACAAACAGCTTATGAAATTGATGAAGAGGTTCGTTCATTATTAAATGAGGCACG
AAATAAAGCTGCTGAAATTATTCAGTCAAATCGTGAAACTCACAAGTTAATTGCAGAAGCATTATTGAAATACGAAACAT
TGGATAGTACACAAATTAAAGCTCTTTACGAAACAGGAAAGATGCCTGAAGCAGTAGAAGAGGAATCTCATGCACTATCC
TATGATGAAGTAAAGTCAAAAATGAATGACGAAAAATAA

Upstream 100 bases:

>100_bases
AGTAGGTTATGGTTTAGACTACAAAGAAAATTATCGTAATCTTCCTTATATTGGAGTATTGAAAGAGGAAGTGTATTCAA
ATTAGAAAGAATAATCTTTA

Downstream 100 bases:

>100_bases
CCCTGAGAGAGGCTGGAGCCTCTCTTTTTTGTGCAGTTTAGGAGCTAAAGGGAACAGAATGGAGAAAATGGAACAAATGT
GTTTTCTAATCTGTTAGACT

Product: cell division protein FtsH

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 652; Mature: 652

Protein sequence:

>652_residues
MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYTELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSK
EGTGIQFFTPSVTKVEKFTSTILPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGARIPAGVLLEGPPGTGKTLLAKAV
AGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAKKAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGF
EGNEGIIVIAATNRSDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFVGADLENVL
NEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHEAGHTIVGLVLSNARVVHKVTIVPRGRAGGY
MIALPKEDQMLLSKEDMKEQLAGLMGGRVAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMLGA
QSPQKSISEQTAYEIDEEVRSLLNEARNKAAEIIQSNRETHKLIAEALLKYETLDSTQIKALYETGKMPEAVEEESHALS
YDEVKSKMNDEK

Sequences:

>Translated_652_residues
MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYTELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSK
EGTGIQFFTPSVTKVEKFTSTILPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGARIPAGVLLEGPPGTGKTLLAKAV
AGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAKKAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGF
EGNEGIIVIAATNRSDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFVGADLENVL
NEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHEAGHTIVGLVLSNARVVHKVTIVPRGRAGGY
MIALPKEDQMLLSKEDMKEQLAGLMGGRVAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMLGA
QSPQKSISEQTAYEIDEEVRSLLNEARNKAAEIIQSNRETHKLIAEALLKYETLDSTQIKALYETGKMPEAVEEESHALS
YDEVKSKMNDEK
>Mature_652_residues
MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYTELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSK
EGTGIQFFTPSVTKVEKFTSTILPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGARIPAGVLLEGPPGTGKTLLAKAV
AGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAKKAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGF
EGNEGIIVIAATNRSDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFVGADLENVL
NEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHEAGHTIVGLVLSNARVVHKVTIVPRGRAGGY
MIALPKEDQMLLSKEDMKEQLAGLMGGRVAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMLGA
QSPQKSISEQTAYEIDEEVRSLLNEARNKAAEIIQSNRETHKLIAEALLKYETLDSTQIKALYETGKMPEAVEEESHALS
YDEVKSKMNDEK

Specific function: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins [H]

COG id: COG0465

COG function: function code O; ATP-dependent Zn proteases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein; Cytoplasmic side [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the peptidase M41 family [H]

Homologues:

Organism=Homo sapiens, GI300192933, Length=622, Percent_Identity=41.6398713826367, Blast_Score=443, Evalue=1e-124,
Organism=Homo sapiens, GI21327685, Length=447, Percent_Identity=47.8747203579418, Blast_Score=412, Evalue=1e-115,
Organism=Homo sapiens, GI7657689, Length=447, Percent_Identity=47.8747203579418, Blast_Score=411, Evalue=1e-114,
Organism=Homo sapiens, GI4507173, Length=607, Percent_Identity=38.3855024711697, Blast_Score=389, Evalue=1e-108,
Organism=Homo sapiens, GI4506209, Length=251, Percent_Identity=44.2231075697211, Blast_Score=207, Evalue=2e-53,
Organism=Homo sapiens, GI24497435, Length=256, Percent_Identity=42.1875, Blast_Score=205, Evalue=1e-52,
Organism=Homo sapiens, GI6005942, Length=238, Percent_Identity=46.6386554621849, Blast_Score=204, Evalue=3e-52,
Organism=Homo sapiens, GI21361144, Length=227, Percent_Identity=43.6123348017621, Blast_Score=196, Evalue=8e-50,
Organism=Homo sapiens, GI89064750, Length=254, Percent_Identity=42.1259842519685, Blast_Score=193, Evalue=4e-49,
Organism=Homo sapiens, GI5729991, Length=254, Percent_Identity=42.1259842519685, Blast_Score=193, Evalue=5e-49,
Organism=Homo sapiens, GI24430155, Length=254, Percent_Identity=42.1259842519685, Blast_Score=192, Evalue=9e-49,
Organism=Homo sapiens, GI45643123, Length=278, Percent_Identity=39.9280575539568, Blast_Score=192, Evalue=1e-48,
Organism=Homo sapiens, GI45643125, Length=278, Percent_Identity=39.9280575539568, Blast_Score=191, Evalue=2e-48,
Organism=Homo sapiens, GI24430151, Length=244, Percent_Identity=40.1639344262295, Blast_Score=191, Evalue=2e-48,
Organism=Homo sapiens, GI195539395, Length=264, Percent_Identity=39.3939393939394, Blast_Score=188, Evalue=1e-47,
Organism=Homo sapiens, GI157671927, Length=225, Percent_Identity=44, Blast_Score=187, Evalue=3e-47,
Organism=Homo sapiens, GI40806173, Length=300, Percent_Identity=40.3333333333333, Blast_Score=185, Evalue=1e-46,
Organism=Homo sapiens, GI4505725, Length=223, Percent_Identity=42.152466367713, Blast_Score=176, Evalue=5e-44,
Organism=Homo sapiens, GI229577436, Length=263, Percent_Identity=40.3041825095057, Blast_Score=171, Evalue=2e-42,
Organism=Homo sapiens, GI24497618, Length=301, Percent_Identity=37.5415282392027, Blast_Score=166, Evalue=5e-41,
Organism=Homo sapiens, GI153792536, Length=245, Percent_Identity=40.4081632653061, Blast_Score=166, Evalue=9e-41,
Organism=Homo sapiens, GI5901990, Length=235, Percent_Identity=40.8510638297872, Blast_Score=154, Evalue=3e-37,
Organism=Homo sapiens, GI194018488, Length=233, Percent_Identity=41.2017167381974, Blast_Score=149, Evalue=1e-35,
Organism=Homo sapiens, GI14149767, Length=239, Percent_Identity=39.7489539748954, Blast_Score=147, Evalue=4e-35,
Organism=Homo sapiens, GI62177112, Length=239, Percent_Identity=39.7489539748954, Blast_Score=147, Evalue=4e-35,
Organism=Homo sapiens, GI226371754, Length=250, Percent_Identity=37.6, Blast_Score=144, Evalue=3e-34,
Organism=Homo sapiens, GI156564401, Length=220, Percent_Identity=38.1818181818182, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI31377644, Length=251, Percent_Identity=37.0517928286853, Blast_Score=137, Evalue=4e-32,
Organism=Homo sapiens, GI11875211, Length=228, Percent_Identity=40.7894736842105, Blast_Score=136, Evalue=5e-32,
Organism=Homo sapiens, GI17865802, Length=263, Percent_Identity=37.6425855513308, Blast_Score=136, Evalue=6e-32,
Organism=Homo sapiens, GI40806170, Length=228, Percent_Identity=40.7894736842105, Blast_Score=136, Evalue=7e-32,
Organism=Homo sapiens, GI31742536, Length=250, Percent_Identity=34.8, Blast_Score=135, Evalue=1e-31,
Organism=Homo sapiens, GI112789543, Length=250, Percent_Identity=34.8, Blast_Score=135, Evalue=1e-31,
Organism=Homo sapiens, GI7019569, Length=269, Percent_Identity=34.2007434944238, Blast_Score=135, Evalue=1e-31,
Organism=Homo sapiens, GI310125282, Length=220, Percent_Identity=37.7272727272727, Blast_Score=133, Evalue=6e-31,
Organism=Homo sapiens, GI310125280, Length=220, Percent_Identity=37.7272727272727, Blast_Score=132, Evalue=8e-31,
Organism=Homo sapiens, GI64084766, Length=276, Percent_Identity=27.536231884058, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI4757852, Length=160, Percent_Identity=33.125, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI119964730, Length=160, Percent_Identity=33.125, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI116292174, Length=224, Percent_Identity=29.9107142857143, Blast_Score=72, Evalue=2e-12,
Organism=Escherichia coli, GI1789568, Length=623, Percent_Identity=49.1171749598716, Blast_Score=576, Evalue=1e-165,
Organism=Caenorhabditis elegans, GI71994521, Length=465, Percent_Identity=50.1075268817204, Blast_Score=422, Evalue=1e-118,
Organism=Caenorhabditis elegans, GI17554264, Length=453, Percent_Identity=47.4613686534216, Blast_Score=388, Evalue=1e-108,
Organism=Caenorhabditis elegans, GI115534323, Length=636, Percent_Identity=36.9496855345912, Blast_Score=375, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI17554786, Length=256, Percent_Identity=43.75, Blast_Score=214, Evalue=1e-55,
Organism=Caenorhabditis elegans, GI25144278, Length=256, Percent_Identity=43.359375, Blast_Score=209, Evalue=4e-54,
Organism=Caenorhabditis elegans, GI25144281, Length=256, Percent_Identity=43.359375, Blast_Score=209, Evalue=4e-54,
Organism=Caenorhabditis elegans, GI17563248, Length=251, Percent_Identity=44.6215139442231, Blast_Score=207, Evalue=1e-53,
Organism=Caenorhabditis elegans, GI17508701, Length=240, Percent_Identity=43.75, Blast_Score=202, Evalue=5e-52,
Organism=Caenorhabditis elegans, GI17531535, Length=235, Percent_Identity=45.531914893617, Blast_Score=195, Evalue=6e-50,
Organism=Caenorhabditis elegans, GI17532375, Length=225, Percent_Identity=40.4444444444444, Blast_Score=192, Evalue=5e-49,
Organism=Caenorhabditis elegans, GI17505546, Length=331, Percent_Identity=37.7643504531722, Blast_Score=189, Evalue=4e-48,
Organism=Caenorhabditis elegans, GI71987364, Length=264, Percent_Identity=39.7727272727273, Blast_Score=189, Evalue=5e-48,
Organism=Caenorhabditis elegans, GI71987372, Length=264, Percent_Identity=39.7727272727273, Blast_Score=189, Evalue=5e-48,
Organism=Caenorhabditis elegans, GI17563250, Length=244, Percent_Identity=40.1639344262295, Blast_Score=185, Evalue=6e-47,
Organism=Caenorhabditis elegans, GI17508053, Length=237, Percent_Identity=42.1940928270042, Blast_Score=175, Evalue=7e-44,
Organism=Caenorhabditis elegans, GI17554784, Length=253, Percent_Identity=39.5256916996047, Blast_Score=175, Evalue=8e-44,
Organism=Caenorhabditis elegans, GI17537217, Length=231, Percent_Identity=41.991341991342, Blast_Score=168, Evalue=8e-42,
Organism=Caenorhabditis elegans, GI25153574, Length=268, Percent_Identity=36.5671641791045, Blast_Score=164, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI133931034, Length=239, Percent_Identity=40.5857740585774, Blast_Score=161, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI193206116, Length=239, Percent_Identity=40.5857740585774, Blast_Score=161, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI193206114, Length=239, Percent_Identity=40.5857740585774, Blast_Score=161, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI193209502, Length=225, Percent_Identity=39.5555555555556, Blast_Score=159, Evalue=5e-39,
Organism=Caenorhabditis elegans, GI17562804, Length=232, Percent_Identity=38.3620689655172, Blast_Score=143, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI86561515, Length=264, Percent_Identity=35.6060606060606, Blast_Score=142, Evalue=6e-34,
Organism=Caenorhabditis elegans, GI17570397, Length=165, Percent_Identity=44.8484848484849, Blast_Score=141, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI32566590, Length=165, Percent_Identity=44.8484848484849, Blast_Score=141, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI25146157, Length=233, Percent_Identity=39.0557939914163, Blast_Score=134, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI133901658, Length=220, Percent_Identity=38.6363636363636, Blast_Score=132, Evalue=6e-31,
Organism=Caenorhabditis elegans, GI133901662, Length=220, Percent_Identity=38.6363636363636, Blast_Score=132, Evalue=8e-31,
Organism=Caenorhabditis elegans, GI32563584, Length=240, Percent_Identity=36.25, Blast_Score=120, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17508421, Length=240, Percent_Identity=36.25, Blast_Score=120, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17541226, Length=237, Percent_Identity=35.8649789029536, Blast_Score=120, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17541224, Length=237, Percent_Identity=35.8649789029536, Blast_Score=119, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI17560432, Length=241, Percent_Identity=34.0248962655602, Blast_Score=114, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6320854, Length=455, Percent_Identity=52.3076923076923, Blast_Score=450, Evalue=1e-127,
Organism=Saccharomyces cerevisiae, GI6323736, Length=576, Percent_Identity=43.2291666666667, Blast_Score=443, Evalue=1e-125,
Organism=Saccharomyces cerevisiae, GI6325281, Length=457, Percent_Identity=44.6389496717724, Blast_Score=386, Evalue=1e-108,
Organism=Saccharomyces cerevisiae, GI6322704, Length=251, Percent_Identity=43.8247011952191, Blast_Score=206, Evalue=9e-54,
Organism=Saccharomyces cerevisiae, GI6321390, Length=244, Percent_Identity=43.0327868852459, Blast_Score=204, Evalue=3e-53,
Organism=Saccharomyces cerevisiae, GI6320077, Length=247, Percent_Identity=44.9392712550607, Blast_Score=202, Evalue=1e-52,
Organism=Saccharomyces cerevisiae, GI6320197, Length=244, Percent_Identity=41.3934426229508, Blast_Score=197, Evalue=4e-51,
Organism=Saccharomyces cerevisiae, GI6324691, Length=255, Percent_Identity=41.1764705882353, Blast_Score=192, Evalue=2e-49,
Organism=Saccharomyces cerevisiae, GI6324833, Length=246, Percent_Identity=41.869918699187, Blast_Score=186, Evalue=9e-48,
Organism=Saccharomyces cerevisiae, GI6320602, Length=259, Percent_Identity=40.9266409266409, Blast_Score=183, Evalue=9e-47,
Organism=Saccharomyces cerevisiae, GI6323429, Length=227, Percent_Identity=43.1718061674009, Blast_Score=174, Evalue=6e-44,
Organism=Saccharomyces cerevisiae, GI6322651, Length=254, Percent_Identity=37.7952755905512, Blast_Score=173, Evalue=7e-44,
Organism=Saccharomyces cerevisiae, GI6322994, Length=255, Percent_Identity=37.2549019607843, Blast_Score=165, Evalue=2e-41,
Organism=Saccharomyces cerevisiae, GI6324000, Length=232, Percent_Identity=40.5172413793103, Blast_Score=164, Evalue=4e-41,
Organism=Saccharomyces cerevisiae, GI6321709, Length=265, Percent_Identity=39.2452830188679, Blast_Score=162, Evalue=2e-40,
Organism=Saccharomyces cerevisiae, GI6325431, Length=252, Percent_Identity=36.5079365079365, Blast_Score=140, Evalue=6e-34,
Organism=Saccharomyces cerevisiae, GI6321465, Length=250, Percent_Identity=38, Blast_Score=140, Evalue=6e-34,
Organism=Saccharomyces cerevisiae, GI6325183, Length=245, Percent_Identity=37.9591836734694, Blast_Score=134, Evalue=4e-32,
Organism=Saccharomyces cerevisiae, GI6319554, Length=263, Percent_Identity=33.8403041825095, Blast_Score=131, Evalue=4e-31,
Organism=Saccharomyces cerevisiae, GI6320887, Length=255, Percent_Identity=33.7254901960784, Blast_Score=114, Evalue=5e-26,
Organism=Saccharomyces cerevisiae, GI6320583, Length=159, Percent_Identity=31.4465408805031, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24665814, Length=610, Percent_Identity=42.4590163934426, Blast_Score=434, Evalue=1e-122,
Organism=Drosophila melanogaster, GI28574878, Length=610, Percent_Identity=42.4590163934426, Blast_Score=434, Evalue=1e-121,
Organism=Drosophila melanogaster, GI24658770, Length=447, Percent_Identity=46.0850111856823, Blast_Score=394, Evalue=1e-109,
Organism=Drosophila melanogaster, GI24639391, Length=648, Percent_Identity=37.8086419753086, Blast_Score=386, Evalue=1e-107,
Organism=Drosophila melanogaster, GI19920408, Length=256, Percent_Identity=42.1875, Blast_Score=206, Evalue=3e-53,
Organism=Drosophila melanogaster, GI17137738, Length=251, Percent_Identity=44.2231075697211, Blast_Score=205, Evalue=7e-53,
Organism=Drosophila melanogaster, GI24651451, Length=256, Percent_Identity=42.578125, Blast_Score=205, Evalue=1e-52,
Organism=Drosophila melanogaster, GI17137560, Length=226, Percent_Identity=42.4778761061947, Blast_Score=204, Evalue=2e-52,
Organism=Drosophila melanogaster, GI161076486, Length=226, Percent_Identity=42.4778761061947, Blast_Score=203, Evalue=2e-52,
Organism=Drosophila melanogaster, GI161076488, Length=226, Percent_Identity=42.4778761061947, Blast_Score=203, Evalue=3e-52,
Organism=Drosophila melanogaster, GI45554047, Length=345, Percent_Identity=37.6811594202899, Blast_Score=202, Evalue=5e-52,
Organism=Drosophila melanogaster, GI281365776, Length=230, Percent_Identity=44.7826086956522, Blast_Score=199, Evalue=4e-51,
Organism=Drosophila melanogaster, GI24660075, Length=230, Percent_Identity=44.7826086956522, Blast_Score=199, Evalue=4e-51,
Organism=Drosophila melanogaster, GI45552965, Length=230, Percent_Identity=44.7826086956522, Blast_Score=198, Evalue=8e-51,
Organism=Drosophila melanogaster, GI17738151, Length=240, Percent_Identity=42.5, Blast_Score=197, Evalue=2e-50,
Organism=Drosophila melanogaster, GI24649446, Length=244, Percent_Identity=40.9836065573771, Blast_Score=192, Evalue=7e-49,
Organism=Drosophila melanogaster, GI18860063, Length=240, Percent_Identity=42.0833333333333, Blast_Score=190, Evalue=3e-48,
Organism=Drosophila melanogaster, GI281361487, Length=240, Percent_Identity=41.25, Blast_Score=189, Evalue=4e-48,
Organism=Drosophila melanogaster, GI19921202, Length=227, Percent_Identity=42.2907488986784, Blast_Score=189, Evalue=4e-48,
Organism=Drosophila melanogaster, GI24652279, Length=189, Percent_Identity=44.4444444444444, Blast_Score=182, Evalue=6e-46,
Organism=Drosophila melanogaster, GI24640100, Length=245, Percent_Identity=40.8163265306122, Blast_Score=181, Evalue=1e-45,
Organism=Drosophila melanogaster, GI24663015, Length=241, Percent_Identity=40.2489626556017, Blast_Score=176, Evalue=4e-44,
Organism=Drosophila melanogaster, GI24656820, Length=254, Percent_Identity=39.7637795275591, Blast_Score=174, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24656825, Length=254, Percent_Identity=39.7637795275591, Blast_Score=174, Evalue=1e-43,
Organism=Drosophila melanogaster, GI281363136, Length=235, Percent_Identity=40.4255319148936, Blast_Score=157, Evalue=2e-38,
Organism=Drosophila melanogaster, GI78707192, Length=235, Percent_Identity=40.4255319148936, Blast_Score=157, Evalue=2e-38,
Organism=Drosophila melanogaster, GI24644145, Length=238, Percent_Identity=40.3361344537815, Blast_Score=154, Evalue=2e-37,
Organism=Drosophila melanogaster, GI21355121, Length=241, Percent_Identity=36.9294605809129, Blast_Score=152, Evalue=8e-37,
Organism=Drosophila melanogaster, GI18859657, Length=237, Percent_Identity=40.9282700421941, Blast_Score=146, Evalue=5e-35,
Organism=Drosophila melanogaster, GI281360136, Length=242, Percent_Identity=38.0165289256198, Blast_Score=144, Evalue=3e-34,
Organism=Drosophila melanogaster, GI24644411, Length=242, Percent_Identity=38.0165289256198, Blast_Score=144, Evalue=3e-34,
Organism=Drosophila melanogaster, GI281360144, Length=242, Percent_Identity=38.0165289256198, Blast_Score=143, Evalue=3e-34,
Organism=Drosophila melanogaster, GI281360140, Length=242, Percent_Identity=38.0165289256198, Blast_Score=143, Evalue=3e-34,
Organism=Drosophila melanogaster, GI281360142, Length=242, Percent_Identity=38.0165289256198, Blast_Score=143, Evalue=4e-34,
Organism=Drosophila melanogaster, GI21357333, Length=242, Percent_Identity=38.0165289256198, Blast_Score=143, Evalue=4e-34,
Organism=Drosophila melanogaster, GI281360146, Length=242, Percent_Identity=38.0165289256198, Blast_Score=142, Evalue=5e-34,
Organism=Drosophila melanogaster, GI281360138, Length=242, Percent_Identity=38.0165289256198, Blast_Score=142, Evalue=5e-34,
Organism=Drosophila melanogaster, GI28571849, Length=234, Percent_Identity=39.7435897435897, Blast_Score=137, Evalue=3e-32,
Organism=Drosophila melanogaster, GI28571847, Length=234, Percent_Identity=39.7435897435897, Blast_Score=137, Evalue=3e-32,
Organism=Drosophila melanogaster, GI20129529, Length=242, Percent_Identity=37.1900826446281, Blast_Score=137, Evalue=3e-32,
Organism=Drosophila melanogaster, GI24581396, Length=238, Percent_Identity=38.655462184874, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI20129423, Length=239, Percent_Identity=35.9832635983264, Blast_Score=132, Evalue=7e-31,
Organism=Drosophila melanogaster, GI17864540, Length=220, Percent_Identity=37.7272727272727, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI28573010, Length=220, Percent_Identity=37.2727272727273, Blast_Score=125, Evalue=6e-29,
Organism=Drosophila melanogaster, GI24639486, Length=252, Percent_Identity=33.3333333333333, Blast_Score=108, Evalue=8e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR003960
- InterPro:   IPR005936
- InterPro:   IPR011546
- InterPro:   IPR000642 [H]

Pfam domain/function: PF00004 AAA; PF06480 FtsH_ext; PF01434 Peptidase_M41 [H]

EC number: 3.4.24.-

Molecular weight: Translated: 71255; Mature: 71255

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS00674 AAA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYTELVQEITDGNVKELTY
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEE
QPNGSVIEVSGVYKNPKTSKEGTGIQFFTPSVTKVEKFTSTILPADTTVSELQKLATDHK
CCCCCEEEEECCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCC
AEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGGGNGRNPMSFGRSKAKAANKE
EEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCHHHHCCCCC
DIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGARIPAGVLLEGPPGTGKTLLAKAV
CEEEEECCCCCCHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHH
AGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAKKAAPAIIFIDEIDAVGRQRGVGLG
CCCCCCCEEECCCHHHHHHHHHCCHHHHHHHHHHHHHHCCEEEEEECHHHHHHHCCCCCC
GGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNRSDVLDPALLRPGRFDRKVLVGRPDVK
CCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCHHHCCCCCCCCEEEECCCCCC
GREAILKVHAKNKPLAEDVDLKLVAQQTPGFVGADLENVLNEAALVAARRNKSIIDASDI
CCCEEEEEECCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCC
DEAEDRVIAGPSKKDKTVSQKERELVAYHEAGHTIVGLVLSNARVVHKVTIVPRGRAGGY
CCCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCEEEEHHHCCCEEEEEEEEEECCCCCCE
MIALPKEDQMLLSKEDMKEQLAGLMGGRVAEEIIFNVQTTGASNDFEQATQMARAMVTEY
EEEECCCCCHHHHHHHHHHHHHHHHCCHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHC
GMSEKLGPVQYEGNHAMLGAQSPQKSISEQTAYEIDEEVRSLLNEARNKAAEIIQSNRET
CCCCCCCCEEECCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
HKLIAEALLKYETLDSTQIKALYETGKMPEAVEEESHALSYDEVKSKMNDEK
HHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHCCCCC
>Mature Secondary Structure
MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYTELVQEITDGNVKELTY
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEE
QPNGSVIEVSGVYKNPKTSKEGTGIQFFTPSVTKVEKFTSTILPADTTVSELQKLATDHK
CCCCCEEEEECCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCC
AEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGGGNGRNPMSFGRSKAKAANKE
EEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCHHHHCCCCC
DIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGARIPAGVLLEGPPGTGKTLLAKAV
CEEEEECCCCCCHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHH
AGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAKKAAPAIIFIDEIDAVGRQRGVGLG
CCCCCCCEEECCCHHHHHHHHHCCHHHHHHHHHHHHHHCCEEEEEECHHHHHHHCCCCCC
GGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNRSDVLDPALLRPGRFDRKVLVGRPDVK
CCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCHHHCCCCCCCCEEEECCCCCC
GREAILKVHAKNKPLAEDVDLKLVAQQTPGFVGADLENVLNEAALVAARRNKSIIDASDI
CCCEEEEEECCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCC
DEAEDRVIAGPSKKDKTVSQKERELVAYHEAGHTIVGLVLSNARVVHKVTIVPRGRAGGY
CCCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCEEEEHHHCCCEEEEEEEEEECCCCCCE
MIALPKEDQMLLSKEDMKEQLAGLMGGRVAEEIIFNVQTTGASNDFEQATQMARAMVTEY
EEEECCCCCHHHHHHHHHHHHHHHHCCHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHC
GMSEKLGPVQYEGNHAMLGAQSPQKSISEQTAYEIDEEVRSLLNEARNKAAEIIQSNRET
CCCCCCCCEEECCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
HKLIAEALLKYETLDSTQIKALYETGKMPEAVEEESHALSYDEVKSKMNDEK
HHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Metalloendopeptidases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11463916 [H]