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The map label for this gene is yicO [C]

Identifier: 116515488

GI number: 116515488

Start: 265768

End: 267186

Strand: Direct

Name: yicO [C]

Synonym: SPD_0267

Alternate gene names: 116515488

Gene position: 265768-267186 (Clockwise)

Preceding gene: 116516913

Following gene: 116516578

Centisome position: 12.99

GC content: 41.58

Gene sequence:

>1419_bases
ATGGACAAATTATTTAAACTAAAAGAGAACGGTACAGACGTTCGTACAGAGGTTCTCGCTGGTTTAACAACTTTCTTTGC
AATGAGCTATATTCTCTTTGTAAACCCACAAATACTTTCACAAACAGGAATGCCTGCTCAGGGTGTCTTCCTAGCGACGA
TTATTGGTGCAGTAGCGGGTACCTTGATGATGGCTTTTTATGCTAACTTACCTTATGCCCAAGCGCCAGGTATGGGACTC
AATGCCTTCTTTACCTTTACAGTTGTATTCGGGCTTGGTTATTCTTGGCAAGAAGCCCTAGCTATGGTCTTCATCTGTGG
GATTATTTCATTGATTATTACCTTGACAAATGTTCGTAAAATGATCATTGAATCGATTCCCAATGCTCTTCGCTCAGCTA
TTTCAGCTGGTATCGGTGTCTTCCTTGCCTATGTAGGGATTAAGAATGCTGGACTTTTGAAATTCACGATTGATCCAGGC
AACTATACTGTTGTAGGAGAAGGGGCTGACAAAGCTCAAGCAACGATTGCAGCAAACTCTTCAGCAGTTCCAGGATTGGT
CAGCTTTAATAATCCAGCTGTTTTAGTGGCTCTTGCAGGACTTGCCATTACTATCTTCTTTGTCATCAAAGGGATTAAAG
GGGGAATTATTCTCTCTATCTTGACAACAACTGTTCTTGCTATTGCAGTTGGTTTGGTTGATTTGTCTAGTATCGATTTT
GCTAATAACCATGTTGGTGCAGCTTTTGAAGATTTGAAGACAATCTTTGGTGCAGCTCTTGGTTCAGAAGGTTTGGGAGC
TTTGGTTTCAGATACAGCTCGCTTGCCTGAAACTCTGATGGCCATTCTTGCCTTCTCATTGACAGATATTTTTGACACAA
TTGGTACCTTGATCGGTACAGGTGAAAAAGTTGGTATCGTAGCGACAAATGGTGAAAATCACCAATCAGCCAAATTGGAT
AAGGCTCTTTACTCTGATTTGATTGGAACGACAGTCGGTGCCATTGCAGGTACTTCAAACGTAACGACTTATGTTGAGTC
TGCTGCTGGTATCGGTGCAGGTGGACGTACTGGTTTGACAGCCTTGGTTGTAGCTATCTGTTTTGCGATTTCAAGCTTCT
TTAGCCCACTTCTAGCGATCGTACCAACAGCGGCTACAGCTCCAATCTTGATTATCGTTGGGATTATGATGCTTGGTAGC
TTGAAAAATATCCATTGGGATGATATGTCTGAAGCAGTTCCTGCCTTCTTCACATCTATCTTTATGGGATTCAGCTACTC
TATCACTCAAGGGATTGCAGTTGGTTTCTTGACTTACACTTTGACTAAGCTTGTTAAAGGTCAAGTTAAAGATGTTCATG
TCATGATTTGGATTTTGGATGCCTTGTTTATCCTTAACTACATCAGCATGGCCTTATAA

Upstream 100 bases:

>100_bases
TGGATTAATTTCTTAAACAAATCAAACAAAGACATTGAAAAAGTGAATGATAAATGATATAATTCTATTATTGTTCGTAA
AAATTAAAAGGAGATTGATG

Downstream 100 bases:

>100_bases
TAGAATGACCCAGGGGGATTTCCCCCCTTTTTTAATACAAAAGGAGATAGGTGATGAAAGAGAAAAATATGTGGAAAGAA
TTGTTGAATCGTGCAGGCTG

Product: xanthine/uracil permease family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 472; Mature: 472

Protein sequence:

>472_residues
MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGMPAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGL
NAFFTFTVVFGLGYSWQEALAMVFICGIISLIITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIILSILTTTVLAIAVGLVDLSSIDF
ANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLPETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLD
KALYSDLIGTTVGAIAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILIIVGIMMLGS
LKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVKDVHVMIWILDALFILNYISMAL

Sequences:

>Translated_472_residues
MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGMPAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGL
NAFFTFTVVFGLGYSWQEALAMVFICGIISLIITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIILSILTTTVLAIAVGLVDLSSIDF
ANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLPETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLD
KALYSDLIGTTVGAIAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILIIVGIMMLGS
LKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVKDVHVMIWILDALFILNYISMAL
>Mature_472_residues
MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGMPAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGL
NAFFTFTVVFGLGYSWQEALAMVFICGIISLIITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIILSILTTTVLAIAVGLVDLSSIDF
ANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLPETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLD
KALYSDLIGTTVGAIAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILIIVGIMMLGS
LKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVKDVHVMIWILDALFILNYISMAL

Specific function: Unknown

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082309, Length=468, Percent_Identity=38.6752136752137, Blast_Score=302, Evalue=2e-83,
Organism=Escherichia coli, GI1790150, Length=470, Percent_Identity=38.2978723404255, Blast_Score=293, Evalue=2e-80,
Organism=Escherichia coli, GI1790499, Length=455, Percent_Identity=31.4285714285714, Blast_Score=202, Evalue=6e-53,
Organism=Escherichia coli, GI48994909, Length=475, Percent_Identity=30.9473684210526, Blast_Score=180, Evalue=2e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 49255; Mature: 49255

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGMPAQGVFLATIIGAVAG
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCHHHHHHHHHHHHH
TLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAMVFICGIISLIITLTNVRK
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
MIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPGNYTVVGEGADKAQATIAANS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEECCCCCHHEEEECCC
SAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIILSILTTTVLAIAVGLVDLSSIDF
CCCCCEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
ANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLPETLMAILAFSLTDIFDTIGTLIGT
CCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GEKVGIVATNGENHQSAKLDKALYSDLIGTTVGAIAGTSNVTTYVESAAGIGAGGRTGLT
CCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCHHHH
ALVVAICFAISSFFSPLLAIVPTAATAPILIIVGIMMLGSLKNIHWDDMSEAVPAFFTSI
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
FMGFSYSITQGIAVGFLTYTLTKLVKGQVKDVHVMIWILDALFILNYISMAL
HHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGMPAQGVFLATIIGAVAG
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCHHHHHHHHHHHHH
TLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAMVFICGIISLIITLTNVRK
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
MIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPGNYTVVGEGADKAQATIAANS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEECCCCCHHEEEECCC
SAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIILSILTTTVLAIAVGLVDLSSIDF
CCCCCEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
ANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLPETLMAILAFSLTDIFDTIGTLIGT
CCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GEKVGIVATNGENHQSAKLDKALYSDLIGTTVGAIAGTSNVTTYVESAAGIGAGGRTGLT
CCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCHHHH
ALVVAICFAISSFFSPLLAIVPTAATAPILIIVGIMMLGSLKNIHWDDMSEAVPAFFTSI
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
FMGFSYSITQGIAVGFLTYTLTKLVKGQVKDVHVMIWILDALFILNYISMAL
HHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]