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The map label for this gene is udg [H]

Identifier: 116515340

GI number: 116515340

Start: 147932

End: 149104

Strand: Direct

Name: udg [H]

Synonym: SPD_0143

Alternate gene names: 116515340

Gene position: 147932-149104 (Clockwise)

Preceding gene: 116516472

Following gene: 116516617

Centisome position: 7.23

GC content: 29.16

Gene sequence:

>1173_bases
ATGAATATAGCAGTAATTGGTTTGGGGCATGTTGGGCTGGCCTACGCGTTACTATTTGCATCTAAATATAAAGTTGTTGC
ATATGATATAGATTCTGTAAAAATAAATAATTTAAAAAAGGGCATTCTTCCATCTAAAAATGAAGAGCTTATGAAGTTTT
TTTGCGAGAATAACTTAAATATTACTTTTTTTGATACATTTTCTGAAATTAAAAATAATATTGATTATTATATTATTGCG
CTTCCGACAGATTATGATGAGAAAATTGGTAGTTTTAATACATATGAAATCGAACAAACGGTATCGAAGATTCTGAGGGT
AAAACCTAATGGAAAGATTATTTTAAAGTCAACAGTTCCGATCGGCTTTTCAAACAAATTAAAAAGGCTGTTTGATACAA
AAAATATCATTTTTGTCCCTGAATTTTTGAGAGAAGGTTGTTCTATATATGATAATTTATATCCAAGTCGCATAGTTGTT
GGAGATGAGACAGTTGAAGGAAGAAAAATTGCAGAGTTGTTCCTTTCGATTAGTACTCATAGTACTGCCAATATTAAAAA
TGTTATGTTAGTTTCTCCTACTGAAGCAGAAGCAATTAAGCTTTTTTCTAACACATTCTTAGCTCTCCGTGTTGCTTTTT
TTAATGAACTAGATTCTTTTGCTGAGAGGAGAAGTTTAAATGCTGAAGTTGTAATAAAAGGTGTTTGTTTAGATCCAAGA
ATTGGAAATTTTTATAATAATCCTTCTTTTGGATTTGGAGGATATTGTCTTCCCAAAGATACTAAACAATTAAAAAAAGA
ATTTATAGAAATAAATGCCCCAGTGATAGAAGCGATTGATATTTCAAACACAAATAGAAAACAGTTCATAGTTAAACAAA
TATTGGAACGAAAGCCAAAGATAGTAGGAATATATAAATTGGGGATGAAATATAATTCAGATAATTACAAAGAGTCAGCT
ATTTTAAGTATAATTAATGAACTATTGATTGTCGGTATAAAAATTTTAGTATATGAACCAAATTTAAACGTTAGTATAGA
TAACGTAATTTTTGAAAAGAATTTTGAACTATTTACAAAACAAAGTGATCTAATTGTTGCAAATAGATGGGATAGGGGCC
TTGAAGCTTATAAAGATAAAGTTTACACAAGGGGGATCTGGATAAGAGATTAA

Upstream 100 bases:

>100_bases
ATCAGTTGAAAAACTTTTAAACAATATTAAAGAGTTGTATTTAAGGAATGGGGCAGCTTATTCTATTAGATTTTGGATTA
AGAAATAAGGAAGTAGTTTT

Downstream 100 bases:

>100_bases
CTATTGATATTAAAAAGGAAATAATTTATAAAATTTGTACAAAAAAATGTTAAATTTTCACATTTTCATAGTATACTGTT
TAATAGAAAGTAGGTTCTTT

Product: UDP-glucose 6-dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 390; Mature: 390

Protein sequence:

>390_residues
MNIAVIGLGHVGLAYALLFASKYKVVAYDIDSVKINNLKKGILPSKNEELMKFFCENNLNITFFDTFSEIKNNIDYYIIA
LPTDYDEKIGSFNTYEIEQTVSKILRVKPNGKIILKSTVPIGFSNKLKRLFDTKNIIFVPEFLREGCSIYDNLYPSRIVV
GDETVEGRKIAELFLSISTHSTANIKNVMLVSPTEAEAIKLFSNTFLALRVAFFNELDSFAERRSLNAEVVIKGVCLDPR
IGNFYNNPSFGFGGYCLPKDTKQLKKEFIEINAPVIEAIDISNTNRKQFIVKQILERKPKIVGIYKLGMKYNSDNYKESA
ILSIINELLIVGIKILVYEPNLNVSIDNVIFEKNFELFTKQSDLIVANRWDRGLEAYKDKVYTRGIWIRD

Sequences:

>Translated_390_residues
MNIAVIGLGHVGLAYALLFASKYKVVAYDIDSVKINNLKKGILPSKNEELMKFFCENNLNITFFDTFSEIKNNIDYYIIA
LPTDYDEKIGSFNTYEIEQTVSKILRVKPNGKIILKSTVPIGFSNKLKRLFDTKNIIFVPEFLREGCSIYDNLYPSRIVV
GDETVEGRKIAELFLSISTHSTANIKNVMLVSPTEAEAIKLFSNTFLALRVAFFNELDSFAERRSLNAEVVIKGVCLDPR
IGNFYNNPSFGFGGYCLPKDTKQLKKEFIEINAPVIEAIDISNTNRKQFIVKQILERKPKIVGIYKLGMKYNSDNYKESA
ILSIINELLIVGIKILVYEPNLNVSIDNVIFEKNFELFTKQSDLIVANRWDRGLEAYKDKVYTRGIWIRD
>Mature_390_residues
MNIAVIGLGHVGLAYALLFASKYKVVAYDIDSVKINNLKKGILPSKNEELMKFFCENNLNITFFDTFSEIKNNIDYYIIA
LPTDYDEKIGSFNTYEIEQTVSKILRVKPNGKIILKSTVPIGFSNKLKRLFDTKNIIFVPEFLREGCSIYDNLYPSRIVV
GDETVEGRKIAELFLSISTHSTANIKNVMLVSPTEAEAIKLFSNTFLALRVAFFNELDSFAERRSLNAEVVIKGVCLDPR
IGNFYNNPSFGFGGYCLPKDTKQLKKEFIEINAPVIEAIDISNTNRKQFIVKQILERKPKIVGIYKLGMKYNSDNYKESA
ILSIINELLIVGIKILVYEPNLNVSIDNVIFEKNFELFTKQSDLIVANRWDRGLEAYKDKVYTRGIWIRD

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=370, Percent_Identity=25.6756756756757, Blast_Score=108, Evalue=7e-24,
Organism=Homo sapiens, GI296040438, Length=267, Percent_Identity=27.7153558052434, Blast_Score=105, Evalue=7e-23,
Organism=Homo sapiens, GI296040443, Length=238, Percent_Identity=26.890756302521, Blast_Score=94, Evalue=2e-19,
Organism=Escherichia coli, GI1788340, Length=391, Percent_Identity=44.2455242966752, Blast_Score=339, Evalue=2e-94,
Organism=Escherichia coli, GI48994968, Length=373, Percent_Identity=25.7372654155496, Blast_Score=79, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17560350, Length=403, Percent_Identity=26.302729528536, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI17136908, Length=370, Percent_Identity=26.4864864864865, Blast_Score=102, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 44509; Mature: 44509

Theoretical pI: Translated: 8.90; Mature: 8.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIAVIGLGHVGLAYALLFASKYKVVAYDIDSVKINNLKKGILPSKNEELMKFFCENNLN
CEEEEEEECHHHHHHHHHHHCCCEEEEEECCCEEECCHHHCCCCCCCHHHHHHHHCCCCC
ITFFDTFSEIKNNIDYYIIALPTDYDEKIGSFNTYEIEQTVSKILRVKPNGKIILKSTVP
EEEEECHHHHHCCCCEEEEEECCCHHHHCCCCCEEEHHHHHHHHHEECCCCCEEEEEECC
IGFSNKLKRLFDTKNIIFVPEFLREGCSIYDNLYPSRIVVGDETVEGRKIAELFLSISTH
CCCHHHHHHHHCCCCEEEEHHHHHCHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHCCC
STANIKNVMLVSPTEAEAIKLFSNTFLALRVAFFNELDSFAERRSLNAEVVIKGVCLDPR
CCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCC
IGNFYNNPSFGFGGYCLPKDTKQLKKEFIEINAPVIEAIDISNTNRKQFIVKQILERKPK
CCCCCCCCCCCCCCEECCCHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCCC
IVGIYKLGMKYNSDNYKESAILSIINELLIVGIKILVYEPNLNVSIDNVIFEKNFELFTK
EEEEEEECEEECCCCCHHHHHHHHHHHHHHEEEEEEEECCCCCEEECCEEEECCCEEEEC
QSDLIVANRWDRGLEAYKDKVYTRGIWIRD
CCCEEEEECCCHHHHHHHHHHEECCEEEEC
>Mature Secondary Structure
MNIAVIGLGHVGLAYALLFASKYKVVAYDIDSVKINNLKKGILPSKNEELMKFFCENNLN
CEEEEEEECHHHHHHHHHHHCCCEEEEEECCCEEECCHHHCCCCCCCHHHHHHHHCCCCC
ITFFDTFSEIKNNIDYYIIALPTDYDEKIGSFNTYEIEQTVSKILRVKPNGKIILKSTVP
EEEEECHHHHHCCCCEEEEEECCCHHHHCCCCCEEEHHHHHHHHHEECCCCCEEEEEECC
IGFSNKLKRLFDTKNIIFVPEFLREGCSIYDNLYPSRIVVGDETVEGRKIAELFLSISTH
CCCHHHHHHHHCCCCEEEEHHHHHCHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHCCC
STANIKNVMLVSPTEAEAIKLFSNTFLALRVAFFNELDSFAERRSLNAEVVIKGVCLDPR
CCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCC
IGNFYNNPSFGFGGYCLPKDTKQLKKEFIEINAPVIEAIDISNTNRKQFIVKQILERKPK
CCCCCCCCCCCCCCEECCCHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCCC
IVGIYKLGMKYNSDNYKESAILSIINELLIVGIKILVYEPNLNVSIDNVIFEKNFELFTK
EEEEEEECEEECCCCCHHHHHHHHHHHHHHEEEEEEEECCCCCEEECCEEEECCCEEEEC
QSDLIVANRWDRGLEAYKDKVYTRGIWIRD
CCCEEEEECCCHHHHHHHHHHEECCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7682279; 11677609 [H]