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The map label for this gene is pnuC [H]

Identifier: 116515309

GI number: 116515309

Start: 1653878

End: 1654684

Strand: Reverse

Name: pnuC [H]

Synonym: SPD_1640

Alternate gene names: 116515309

Gene position: 1654684-1653878 (Counterclockwise)

Preceding gene: 116516671

Following gene: 116516957

Centisome position: 80.87

GC content: 41.88

Gene sequence:

>807_bases
ATGCATACTTATTTGCAAAAGAAAATTGAAAATATCAAAACAACCCTAGGTGAAATGTCAGGTGGTTACCGTCGTATGGT
TGCGGCTATGGCTGATTTAGGATTTTCAGGAACTATGAAGGCTATCTGGGATGACCTCTTTGCCCATCGTAGTTTTGCCC
AGTGGATTTATTTGCTGGTTTTAGGAAGTTTTCCTCTCTGGCTGGAGTTGGTTTACGAACATCGTATTGTTGACTGGATT
GGGATGATTTGTAGCTTGACAGGGATTATCTGTGTAATCTTTGTATCGGAAGGTCGAGCAAGTAATTATCTTTTTGGCTT
GATTAACTCTGTTATTTACCTTATTTTGGCCCTACAGAAAGGCTTTTATGGTGAGGTGCTGACGACACTTTACTTCACAG
TCATGCAGCCAATTGGACTTCTAGTTTGGATTTATCAGGCACAGTTTAAGAAGGAAAAGCAGGAGTTTGTCGCGCGTAAA
CTGGACGGCAAGGGCTGGACAAAGTATCTTTCCATTAGTGTGCTTTGGTGGTTGGCCTTTGGCTTCATTTATCAGTCTAT
TGGTGCCAATCGTCCCTATCGTGATTCAATCACAGATGCAACCAATGGGGTAGGGCAAATCCTCATGACAGCTGTTTACC
GTGAACAGTGGATATTCTGGGCGGCTACCAATGTCTTTTCAATCTATCTCTGGTGGGGAGAAAGCCTGCAAATTCAAGGG
AAATATCTAATTTATCTCATTAACAGTCTAGTTGGTTGGTATCAATGGAGCAAGGCAGCTAAGCAGAATACTGATTTACT
TAACTAG

Upstream 100 bases:

>100_bases
TAAGGTTAGAAATCTTGTGTATAGGCAGTTCATTATCTAATAGAGCGTTGCGTCCGAAAGTCTATCCAGACACGGCTCTT
AAAAAACAAAAGGAGAAATG

Downstream 100 bases:

>100_bases
GAAAAGATGTTTGAAAGTGCTGTTTTGAGATTTCGATTAAAACAGATATAGTTGATAATCAAGGATTTATAGTATGAAAA
AGAGGATCGGCGGGTCCTCT

Product: nicotinamide mononucleotide transporter PnuC

Products: nicotinamide nucleotide [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWDDLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWI
GMICSLTGIICVIFVSEGRASNYLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWIFWAATNVFSIYLWWGESLQIQG
KYLIYLINSLVGWYQWSKAAKQNTDLLN

Sequences:

>Translated_268_residues
MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWDDLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWI
GMICSLTGIICVIFVSEGRASNYLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWIFWAATNVFSIYLWWGESLQIQG
KYLIYLINSLVGWYQWSKAAKQNTDLLN
>Mature_268_residues
MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWDDLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWI
GMICSLTGIICVIFVSEGRASNYLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWIFWAATNVFSIYLWWGESLQIQG
KYLIYLINSLVGWYQWSKAAKQNTDLLN

Specific function: Required for nicotinamide riboside transport across the inner membrane [H]

COG id: COG3201

COG function: function code H; Nicotinamide mononucleotide transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006419 [H]

Pfam domain/function: PF04973 NMN_transporter [H]

EC number: NA

Molecular weight: Translated: 31031; Mature: 31031

Theoretical pI: Translated: 9.25; Mature: 9.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWDDLFAHRSFAQWIYLLV
CCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASNYLFGLINSVIYLILALQK
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHC
GFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARKLDGKGWTKYLSISVLWWLAF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
GFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWIFWAATNVFSIYLWWGESLQIQG
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEHHHHEEEEEEECCCEEECC
KYLIYLINSLVGWYQWSKAAKQNTDLLN
HHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWDDLFAHRSFAQWIYLLV
CCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASNYLFGLINSVIYLILALQK
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHC
GFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARKLDGKGWTKYLSISVLWWLAF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
GFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWIFWAATNVFSIYLWWGESLQIQG
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEHHHHEEEEEEECCCEEECC
KYLIYLINSLVGWYQWSKAAKQNTDLLN
HHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: nicotinamide nucleotide [Periplasm] [C]

Specific reaction: nicotinamide nucleotide [Periplasm] = nicotinamide nucleotide [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12446641; 7542800 [H]