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The map label for this gene is trxA [H]

Identifier: 116515297

GI number: 116515297

Start: 403700

End: 404035

Strand: Reverse

Name: trxA [H]

Synonym: BCc_386

Alternate gene names: 116515297

Gene position: 404035-403700 (Counterclockwise)

Preceding gene: 116515298

Following gene: 116515296

Centisome position: 97.04

GC content: 18.75

Gene sequence:

>336_bases
ATGAAGGTTACTAAAATTATTGAATTAACAGATCAAAATTTTGAAAAAAAAGTTTTTTTTTCTAAAAAATTTTTTTTGGT
TGATTTTTGGGCTGATTGGTGTGGTCCATGTAAAATTTTATCACCAATATTAGAAGAGATAGCACATGAATATTACAAAA
AAATTTTTATAGGAAAAATTAATATTGATATAAATAAAAATATACCTATTAAATTTTCTATTAAAGGTATTCCCGCATTA
TTGTTATTTAATAAAAAAAAAATTATAGGTACTAAAATAGGTTTAATTACAAAAGTAGAATTAAAAAATTTTTTAGATAA
AAAAATAGTTACTTAA

Upstream 100 bases:

>100_bases
TAGTAATTTAATTATTTTATATTATTAAAATAATGAAATAATATTTAAATGTATTAAATTTTTGATAATTTTATGATTAA
TATAATATATTAGGATATTT

Downstream 100 bases:

>100_bases
GAATATATTTTTATTTTTAAAATAATTTATTAATACAAAAATATATTTAATCAATTTTTTTTTTATATTTAAATTACTAA
TAATTTATTATTAATGATGA

Product: hypothetical protein

Products: NA

Alternate protein names: Trx [H]

Number of amino acids: Translated: 111; Mature: 111

Protein sequence:

>111_residues
MKVTKIIELTDQNFEKKVFFSKKFFLVDFWADWCGPCKILSPILEEIAHEYYKKIFIGKINIDINKNIPIKFSIKGIPAL
LLFNKKKIIGTKIGLITKVELKNFLDKKIVT

Sequences:

>Translated_111_residues
MKVTKIIELTDQNFEKKVFFSKKFFLVDFWADWCGPCKILSPILEEIAHEYYKKIFIGKINIDINKNIPIKFSIKGIPAL
LLFNKKKIIGTKIGLITKVELKNFLDKKIVT
>Mature_111_residues
MKVTKIIELTDQNFEKKVFFSKKFFLVDFWADWCGPCKILSPILEEIAHEYYKKIFIGKINIDINKNIPIKFSIKGIPAL
LLFNKKKIIGTKIGLITKVELKNFLDKKIVT

Specific function: Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions [H]

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI21361403, Length=97, Percent_Identity=31.9587628865979, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI87082331, Length=106, Percent_Identity=49.0566037735849, Blast_Score=118, Evalue=1e-28,
Organism=Escherichia coli, GI1788936, Length=84, Percent_Identity=29.7619047619048, Blast_Score=70, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17549970, Length=79, Percent_Identity=39.2405063291139, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI212646193, Length=96, Percent_Identity=33.3333333333333, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17507705, Length=87, Percent_Identity=29.8850574712644, Blast_Score=65, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17556044, Length=79, Percent_Identity=39.2405063291139, Blast_Score=64, Evalue=1e-11,
Organism=Drosophila melanogaster, GI28573567, Length=100, Percent_Identity=30, Blast_Score=77, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24639826, Length=80, Percent_Identity=30, Blast_Score=72, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24664269, Length=66, Percent_Identity=31.8181818181818, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00085 Thioredoxin [H]

EC number: NA

Molecular weight: Translated: 12949; Mature: 12949

Theoretical pI: Translated: 10.38; Mature: 10.38

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVTKIIELTDQNFEKKVFFSKKFFLVDFWADWCGPCKILSPILEEIAHEYYKKIFIGKI
CCCEEEEEECCCCCCEEEEECCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHEEEEE
NIDINKNIPIKFSIKGIPALLLFNKKKIIGTKIGLITKVELKNFLDKKIVT
EEEECCCCCEEEEECCCCEEEEECCCCCCEEECCEEEHHHHHHHHHHHCCC
>Mature Secondary Structure
MKVTKIIELTDQNFEKKVFFSKKFFLVDFWADWCGPCKILSPILEEIAHEYYKKIFIGKI
CCCEEEEEECCCCCCEEEEECCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHEEEEE
NIDINKNIPIKFSIKGIPALLLFNKKKIIGTKIGLITKVELKNFLDKKIVT
EEEECCCCCEEEEECCCCEEEEECCCCCCEEECCEEEHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Reduction reactions; participates in dithiol-disulfide exchange reactions [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10993077 [H]